Antenatal dexamethasone has no adverse effects on child physical and cognitive development: A long-term cohort follow-up investigation

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 25, Issue 11, 2012, Pages 2369-2371

  Liu, Jing ^a   Feng, Zhi Chun ^a   Li, Jian ^b   Wang, Qi ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Antenatal dexamethasone; Cognitive development; Long term follow up; Physical development

Indexed keywords

DEXAMETHASONE;

ARTICLE; BIRTH WEIGHT; BODY HEIGHT; BODY WEIGHT; CHILD; CHILD DEVELOPMENT; COGNITIVE DEVELOPMENT; COHORT ANALYSIS; CONTROLLED STUDY; DEVELOPMENTAL, AGE AND GROWTH PARAMETERS; DRUG SAFETY; FOLLOW UP; GESTATIONAL AGE; HEAD CIRCUMFERENCE; HUMAN; INFANT; LONG TERM CARE; MENTAL DEVELOPMENT INDEX; NERVOUS SYSTEM PARAMETERS; NEWBORN DISEASE; PERFORMANCE INTELLIGENCE QUOTIENT; PERINATAL DEVELOPMENT; PHYSICAL DEVELOPMENT; PRENATAL DRUG EXPOSURE; PRESCHOOL CHILD; PRIORITY JOURNAL; PSYCHOMOTOR DEVELOPMENT INDEX; RETROSPECTIVE STUDY; SIDE EFFECT; VERBAL INTELLIGENCE QUOTIENT;

ADULT; ANTI-INFLAMMATORY AGENTS; CHILD DEVELOPMENT; CHILD, PRESCHOOL; COGNITION; COHORT STUDIES; DEXAMETHASONE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; INFANT, NEWBORN; MALE; MOTOR ACTIVITY; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 84867558086     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2012.696162     Document Type: Article

References (26)

1. Roberts D, Dalziel S. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev 2006;3:CD004454.
2. Canterino JC, Verma U, Visintainer PF, Elimian A, Klein SA, Tejani N. Antenatal steroids and neonatal periventricular leukomalacia. Obstet Gynecol 2001;97:135-139. (Pubitemid 32057171)
3. Liu J, Wang Q, Zhao JH, Chen YH, Qin GL. The combined antenatal corticosteroids and vitamin K therapy for preventing periventricular- intraventricular hemorrhage in premature newborns less than 35 weeks gestation. J Trop Pediatr 2006;52:355-359. (Pubitemid 44542355)
4. Sweet DG, Carnielli V, Greisen G, Hallman M, Ozek E, Plavka R, Saugstad OD, et al.; European Association of Perinatal Medicine. European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2010 update. Neonatology 2010;97:402-417.
5. Banks BA, Cnaan A, Morgan MA, Parer JT, Merrill JD, Ballard PL, Ballard RA. Multiple courses of antenatal corticosteroids and outcome of premature neonates. North American Thyrotropin-Releasing Hormone Study Group. Am J Obstet Gynecol 1999;181:709-717. (Pubitemid 29453537)
6. Stewart JD, Gonzalez CL, Christensen HD, Rayburn WF. Impact of multiple antenatal doses of betamethasone on growth and development of mice offspring. Am J Obstet Gynecol 1997;177:1138-1144. (Pubitemid 27525372)
7. Pratt L, Magness RR, Phernetton T, Hendricks SK, Abbott DH, Bird IM. Repeated use of betamethasone in rabbits: effects of treatment variation on adrenal suppression, pulmonary maturation, and pregnancy outcome. Am J Obstet Gynecol 1999;180:995-1005. (Pubitemid 29200567)
8. Sun B, Jobe A, Rider E, Ikegami M. Single dose versus two doses of betamethasone for lung maturation in preterm rabbits. Pediatr Res 1993;33:256-260. (Pubitemid 23101838)
9. Ikegami M, Jobe AH, Newnham J, Polk DH, Willet KE, Sly P. Repetitive prenatal glucocorticoids improve lung function and decrease growth in preterm lambs. Am J Respir Crit Care Med 1997;156:178-184. (Pubitemid 27293185)
10. Kumar P, Seshadri R. Neonatal morbidity and growth in very low birth-weight infants after multiple courses of antenatal steroids. J Perinatol 2005;25:698-702. (Pubitemid 41655643)
11. Koenen S V, Mulder EJ, Wijnberger LD, Visser GH. Transient loss of the diurnal rhythms of fetal movements, heart rate, and its variation after maternal betamethasone administration. Pediatr Res 2005;57:662-666. (Pubitemid 40578035)
12. Mulder EJ, de Heus R, Visser GH. Antenatal corticosteroid therapy: short-term effects on fetal behaviour and haemodynamics. Semin Fetal Neonatal Med 2009;14:151-156.
13. Bayley N. Bayley scales of infant development. 2nd ed. San Antonio, TX: The Psychological Corporation; 1993.
14. Wechsler D. WPPSI-R, manual: Wechsler Preschool and Primary Scale of intelligence-revised. San Antonio, TX: Psychological Corporation; 1989.
15. Crowley P, Chalmers I, Keirse MJ. The effects of corticosteroid administration before preterm delivery: an overview of the evidence from controlled trials. Br J Obstet Gynaecol 1990;97:11-25. (Pubitemid 20136124)
16. Jobe AH, Mitchell BR, Gunkel JH. Beneficial effects of the combined use of prenatal corticosteroids and postnatal surfactant on preterm infants. Am J Obstet Gynecol 1993;168:508-513. (Pubitemid 23069102)
17. Lee BH, Stoll BJ, McDonald SA, Higgins RD; National Institute of Child Health and Human Development Neonatal Research Network. Neurodevelopmental outcomes of extremely low birth weight infants exposed prenatally to dexamethasone versus betamethasone. Pediatrics 2008;121:289-296. (Pubitemid 351198451)
18. US Antenatal Steroid Trial, Collaborative Group on Antenatal Steroid Therapy. Effects of antenatal dexamethasone administration in the infant: long-term follow-up. J Pediatr 1984;10:259-267.
19. O'Shea TM, Kothadia JM, Klinepeter KL, Goldstein DJ, Jackson BG, Weaver RG 3rd, Dillard RG. Randomized placebo-controlled trial of a 42-day tapering course of dexamethasone to reduce the duration of ventilator dependency in very low birth weight infants: outcome of study participants at 1-year adjusted age. Pediatrics 1999;104:15-21. (Pubitemid 29315841)
20. Shinwell ES, Karplus M, Reich D, Weintraub Z, Blazer S, Bader D, Yurman S, et al. Early postnatal dexamethasone treatment and increased incidence of cerebral palsy. Arch Dis Child Fetal Neonatal Ed 2000;83:F177-F181.
21. Yeh TF, Lin YJ, Lin HC, Huang CC, Hsieh WS, Lin CH, Tsai CH. Outcomes at school age after postnatal dexamethasone therapy for lung disease of prematurity. N Engl J Med 2004;350:1304-1313. (Pubitemid 38375365)
22. Barrington KJ. The adverse neuro-developmental effects of postnatal steroids in the preterm infant: a systematic review of RCTs. BMC Pediatr 2001;1:1.
23. Halliday HL, Ehrenkranz RA, Doyle LW. Early postnatal (<96 hours) corticosteroids for preventing chronic lung disease in preterm infants. Cochrane Database Syst Rev 2003;1:CD001146.
24. LeFlore JL, Salhab WA, Broyles RS, Engle WD. Association of antenatal and postnatal dexamethasone exposure with outcomes in extremely low birth weight neonates. Pediatrics 2002;110:275-279. (Pubitemid 34833010)
25. Wilson-Costello D, Walsh MC, Langer JC, Guillet R, Laptook AR, Stoll BJ, Shankaran S, et al.; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Impact of postnatal corticosteroid use on neurodevelopment at 18 to 22 months' adjusted age: effects of dose, timing, and risk of bronchopulmonary dysplasia in extremely low birth weight infants. Pediatrics 2009;123:e430-e437.
26. Roberge S, Lacasse Yve, Tapp S, Tremblay Y, Kari A, Liu J, Fekih M, Qublan HS, Amorim MM, Bujold E. Role of fetal sex in the outcome of antenatal glucocorticoid treatment to prevent respiratory distress syndrome: systematic review and Meta-analysis. J Obstet Gynaecol Can 2011;33:216-226.