Internal anal sphincter relaxation associated with bisacodyl-induced colonic high amplitude propagating contractions in children with constipation: A colo-anal reflex?

Neurogastroenterology and Motility

Volumn 24, Issue 11, 2012, Pages

  Rodriguez, L ^a   Siddiqui, A ^a   Nurko, S ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Anal sphincter relaxation; Children; Colo anal reflex; Colonic high amplitude propagating contractions; Constipation

Indexed keywords

BISACODYL;

ANORECTAL PRESSURE; ANUS SPHINCTER; ARTICLE; CHILD; COLON MOTILITY; CONSTIPATION; FEMALE; HIGH AMPLITUDE PERISTALTIC CONTRACTION; HUMAN; INTESTINE CONTRACTION; MAJOR CLINICAL STUDY; MALE; MUSCLE RELAXATION; PERISTALSIS; PRIORITY JOURNAL; REFLEX; RETROSPECTIVE STUDY; SIGMOID;

ANAL CANAL; BISACODYL; CATHARTICS; CHILD; COLON; CONSTIPATION; FEMALE; HUMANS; MALE; MANOMETRY; MUSCLE RELAXATION; MYOELECTRIC COMPLEX, MIGRATING; PERISTALSIS; REFLEX; RETROSPECTIVE STUDIES;

EID: 84867549652     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2012.01965.x     Document Type: Article

References (23)

1. Kamm MA, van der Sijp JR, Lennard-Jones JE. Observations on the characteristics of stimulated defaecation in severe idiopathic constipation. Int J Colorectal Dis 1992; 7: 197-201.
2. Malcolm A, Camilleri M. Coloanal motor coordination in association with high-amplitude colonic contractions after pharmacological stimulation. Am J Gastroenterol 2000; 95: 715-9.
3. Kamm MA, van der Sijp JR, Lennard-Jones JE. Colorectal and anal motility during defaecation. Lancet 1992; 339: 820.
4. Di Lorenzo C, Flores AF, Reddy SN et al. Use of colonic manometry to differentiate causes of intractable constipation in children. J Pediatr 1992; 120: 690-5.
5. Narducci F, Bassotti G, Gaburri M et al. Twenty four hour manometric recording of colonic motor activity in healthy man. Gut 1987; 28: 17-25.
6. Bassotti G, Gaburri M. Manometric investigation of high-amplitude propagated contractile activity of the human colon. Am J Physiol 1988; 255: G660-4.
7. Bassotti G, Clementi M, Antonelli E et al. Low-amplitude propagated contractile waves: a relevant propulsive mechanism of human colon. Dig Liver Dis 2001; 33: 36-40.
8. Bassotti G, Chistolini F, Nzepa FS et al. Colonic propulsive impairment in intractable slow-transit constipation. Arch Surg 2003; 138: 1302-4.
9. Bassotti G, Chistolini F, Marinozzi G et al. Abnormal colonic propagated activity in patients with slow transit constipation and constipation-predominant irritable bowel syndrome. Digestion 2003; 68: 178-83.
10. Chumpitazi BP, Fishman SJ, Nurko S. Long-term clinical outcome after botulinum toxin injection in children with nonrelaxing internal anal sphincter. Am J Gastroenterol 2009; 104: 976-83.
11. Liem O, Burgers RE, Connor FL et al. Solid-state vs water-perfused catheters to measure colonic high-amplitude propagating contractions. Neurogastroenterol Motil 2012; 24: 345-e167.
12. Arkwright JW, Underhill ID, Maunder SA et al. Design of a high-sensor count fibre optic manometry catheter for in-vivo colonic diagnostics. Opt Express 2009; 17: 22423-31.
13. Davidson JB, O'Grady G, Arkwright JW et al. Anatomical registration and three-dimensional visualization of low and high-resolution pan-colonic manometry recordings. Neurogastroenterol Motil 2011; 23: 387-90, e171.
14. Bampton PA, Dinning PG, Kennedy ML et al. Spatial and temporal organization of pressure patterns throughout the unprepared colon during spontaneous defecation. Am J Gastroenterol 2000; 95: 1027-35.
15. Musial F, Enck P, Kalveram KT et al. The effect of loperamide on anorectal function in normal healthy men. J Clin Gastroenterol 1992; 15: 321-4.
16. Radomirov R, Ivancheva C, Itzev D et al. Locality-dependent descending reflex motor activity in the anal canal--cholinergic and nitrergic contributions in the rat model. Acta Pharmacol Sin 2009; 30: 1276-82.
17. Hamid SA, Di Lorenzo C, Reddy SN et al. Bisacodyl and high-amplitude-propagating colonic contractions in children. J Pediatr Gastroenterol Nutr 1998; 27: 398-402.
18. Schang JC, Hemond M, Hebert M et al. Changes in colonic myoelectric spiking activity during stimulation by bisacodyl. Can J Physiol Pharmacol 1986; 64: 39-43.
19. Manabe N, Cremonini F, Camilleri M et al. Effects of bisacodyl on ascending colon emptying and overall colonic transit in healthy volunteers. Aliment Pharmacol Ther 2009; 30: 930-6.
20. Gosselink MJ, Hop WC, Schouten WR. Rectal tone in response to bisacodyl in women with obstructed defecation. Int J Colorectal Dis 2000; 15: 297-302.
21. Ikarashi N, Baba K, Ushiki T et al. The laxative effect of bisacodyl is attributable to decreased aquaporin-3 expression in the colon induced by increased PGE2 secretion from macrophages. Am J Physiol Gastrointest Liver Physiol 2011; 301: G887-95.
22. Karmeli F, Stalnikowicz R, Rachmilewitz D. Effect of colchicine and bisacodyl on rat intestinal transit and nitric oxide synthase activity. Scand J Gastroenterol 1997; 32: 791-6.
23. Gaginella TS, Mascolo N, Izzo AA et al. Nitric oxide as a mediator of bisacodyl and phenolphthalein laxative action: induction of nitric oxide synthase. J Pharmacol Exp Ther 1994; 270: 1239-45.