Once-daily fluticasone furoate is efficacious in patients with symptomatic asthma on low-dose inhaled corticosteroids

Annals of Allergy, Asthma and Immunology

Volumn 109, Issue 5, 2012, Pages

  Bleecker, Eugene R ^a   Bateman, Eric D ^b   Busse, William W ^c   Woodcock, Ashley ^d   Frith, Lucy ^e   House, Karen W ^f   Jacques, Loretta ^e   Davis, Angela M ^f   Haumann, Brett ^e,g   Lötvall, Jan ^h  

^a WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e GLAXOSMITHKLINE   (United Kingdom)

^f GLAXOSMITHKLINE   (United States)

^g CIRCASSIA LTD   (United Kingdom)

^h UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; FLUTICASONE FUROATE; FLUTICASONE PROPIONATE; HYDROCORTISONE; PLACEBO;

AGED; ARTICLE; ASTHMA; BEDTIME DOSAGE; CHILD; COLITIS; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; FORCED EXPIRATORY VOLUME; HEADACHE; HEART INFARCTION; HUMAN; HYDROCORTISONE URINE LEVEL; KNEE INJURY; LONG TERM CARE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OROPHARYNX CANDIDIASIS; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHINOPHARYNGITIS; SCHOOL CHILD; THROAT IRRITATION; URINARY EXCRETION;

EID: 84867529948     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/j.anai.2012.08.017     Document Type: Article

References (51)

1. Global Initiative for Asthma (GINA) Global Strategy for Asthma Management and Prevention 2011 www.ginasthma.org Accessed May 28, 2012
2. National Institutes of Health (NIH) Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma Full Report 2007 NIH Publication No. 08-4051 http://www.nhlbi.nih.gov/guidelines/asthma/asthgdln.htm Accessed May 28, 2012
3. British Thoracic Society (BTS) British Guideline on the Management of Asthma www.brit-thoracic.org.uk 2011 Accessed May 28, 2012
4. T. Haahtela, M. Jävinen, T. Kava et al. Effects of reducing or discontinuing inhaled budesonide in patients with mild asthma N Engl J Med 331 1994 700 705
5. R.A. Pauwels, S. Pedersen, W.W. Busse Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial Lancet 361 2003 1071 1076
6. S. Pedersen, P. O'Byrne A comparison of efficacy and safety of inhaled corticosteroids in asthma Allergy 52 1997 1 34
7. J.M. FitzGerald, P.G. Gibson Asthma exacerbations. 4: Prevention Thorax 61 2006 992 999
8. S. Suissa, P. Ernst, S. Benayoun, M. Baltzan, B. Cai Low-dose inhaled corticosteroids and the prevention of death from asthma N Engl J Med 343 2000 332 336
9. M. Mintz, A.W. Gilsenan, C.L. Bui Assessment of asthma control in primary care Curr Med Res Opin 25 2009 2523 2531
10. C. Jones, N.C. Santanello, S.J. Boccuzzi, J. Wogen, P. Strub, L.M. Nelsen Adherence to prescribed treatment for asthma: evidence from pharmacy benefits data J Asthma 40 2003 93 101
11. R.H. Stanford, A.W. Gilsenan, R. Ziemiecki, X. Zhou, W.R. Lincourt, H. Ortega Predictors of uncontrolled asthma in adult and pediatric patients: analysis of the Asthma Control Characteristics and Prevalence Survey Studies (ACCESS) J Asthma 47 2010 257 262
12. G.M. Cochrane, R. Horne, P. Chanez Compliance in asthma Respir Med 93 1999 763 769
13. D. Price, A. Robertson, K. Bullen, C. Rand, R. Horne, H. Staudinger Improved adherence with once-daily versus twice-daily dosing of mometasone furoate administered via a dry powder inhaler: a randomized open-label study BMC Pulm Med 10 2010 1
14. J.F. Guest, A.M. Davie, F.J. Ruiz, M.J. Greener Switching asthma patients to a once-daily inhaled steroid improves compliance and reduces healthcare costs Prim Care Respir J 14 2005 88 98
15. E.R. Sutherland Nocturnal asthma: underlying mechanisms and treatment Curr Allergy Asthma Rep 5 2005 161 167
16. R.J. Martin Nocturnal asthma: circadian rhythms and therapeutic interventions Am Rev Respir Dis 147 1993 S25 S28
17. H. Greenberg, R.I. Cohen Nocturnal asthma Curr Opin Pulm Med 18 2012 57 62
18. A.H. Jones, C.G. Langdon, P.S. Lee, S.A. Lingham, J.P. Nankani, R.M. Follows, U. Tollemar, P.D. Richardson Pulmicort Turbohaler once daily as initial prophylactic therapy for asthma Respir Med 88 1994 293 299
19. M. Noonan, J.P. Karpel, G.W. Bensch, J.W. Ramsdell, D.R. Webb, K.B. Nolop, B.N. Lutsky Comparison of once-daily to twice-daily treatment with mometasone furoate dry powder inhaler Ann Allergy Asthma Immunol 86 2001 36 43
20. D.S. Postma, C. Sevette, Y. Martinat, N. Schlösser, J. Aumann, H. Kafé Treatment of asthma by the inhaled corticosteroid ciclesonide given either in the morning or evening Eur Respir J 17 2001 1083 1088
21. M. van den Berge, B. Luijk, P. Bareille, N. Dallow, D.S. Postma, J.-W.J. Lammers Prolonged protection of the new inhaled corticosteroid fluticasone furoate against AMP hyperresponsiveness in patients with asthma Allergy 65 2010 1531 1535
22. K. Biggadike, R.K. Bledsoe, A.M. Hassell X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain J Med Chem 51 2008 3349 3352
23. M. Salter, K. Biggadike, J.L. Matthews Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease Am J Physiol Lung Cell Mol Physiol 293 2007 L660 L667
24. E.R. Bleecker, E.D. Bateman, W. Busse Fluticasone furoate (FF), an inhaled corticosteroid (ICS), is efficacious in asthma patients symptomatic on low doses of ICS therapy Eur Respir J 36 Suppl.54 2010 204s
25. J.L. Hankinson, J.R. Odencrantz, K.B. Fedan Spirometric reference values from a sample of the general U.S. population Am J Respir Crit Care Med 159 1999 179 187
26. W.C. Moore, E.R. Bleecker, D. Curran-Everett Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program J Allergy Clin Immunol 119 2007 405 413
27. W.C. Moore, D.A. Meyers, S.E. Wenzel Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program Am J Respir Crit Care Med 181 2010 315 323
28. A. Miller Lung function testing: selection of reference values and interpretative strategies Am Rev Respir Dis 146 1992 1368 1369
29. D.H. Arnold, T. Gebretsadik, P.A. Minton, S. Higgins, T.V. Hartert Clinical measures associated with FEV1 in persons with asthma requiring hospital admission Am J Emerg Med 25 2007 425 429
30. E.F. Juniper, J. Bousquet, L. Abetz, E.D. Bateman Identifying 'well-controlled' and 'not well-controlled' asthma using the Asthma Control Questionnaire Respir Med 100 2006 616 621
31. H.K. Reddel, D.R. Taylor, E.D. Bateman ATS/ERS Task Force on Asthma Control and Exacerbations An official ATS/ERS statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice Am J Respir Crit Care Med 180 2009 59 99
32. J.D. Wolfe, J.C. Selner, L.M. Mendelson, F. Hampel Jr, A. Schaberg Effectiveness of fluticasone propionate in patients with moderate asthma: a dose-ranging study Clin Ther 18 1996 635 646
33. S.I. Wasserman, G.N. Gross, W.F. Schoenwetter A 12-week dose-ranging study of fluticasone propionate powder in the treatment of asthma J Asthma 33 1996 265 274
34. N.P. Adams, P.W. Jones The dose-response characteristics of inhaled corticosteroids when used to treat asthma: an overview of Cochrane systematic reviews Respir Med 100 2006 1297 1306
35. M. Masoli, M. Weatherall, S. Holt, R. Beasley Clinical dose-response relationship of fluticasone propionate in adults with asthma Thorax 59 2004 16 20
36. E.D. Bateman, E.R. Bleecker, J. Lötvall Dose effect of once-daily fluticasone furoate in persistent asthma: a randomized trial Respir Med 106 2012 642 650
37. W. Busse, E.R. Bleecker, E.D. Bateman Fluticasone furoate demonstrates efficacy in asthma patients symptomatic on medium doses of inhaled corticosteroid therapy: a randomised, placebo-controlled trial Thorax 67 2012 35 41
38. H.W. Kelly Inhaled corticosteroid dosing: double for nothing? J Allergy Clin Immunol 128 2011 278 281
39. A.P. Greening, P.W. Ind, M. Northfield, G. Shaw Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid Allen & Hanburys Limited UK Study Group Lancet 344 1994 219 224
40. R.A. Pauwels, C.G. Löfdahl, D.S. Postma Effect of inhaled formoterol and budesonide on exacerbations of asthma Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group N Engl J Med 337 1997 1405 1411
41. J. Matz, A. Emmett, K. Rickard, C. Kalberg Addition of salmeterol to low-dose fluticasone versus higher-dose fluticasone: an analysis of asthma exacerbations J Allergy Clin Immunol 107 2001 783 789
42. E. Bateman, H. Nelson, J. Bousquet Meta-analysis: effects of adding salmeterol to inhaled corticosteroids on serious asthma-related events Ann Intern Med 149 2008 33 42
43. S.P. Peters, S.J. Kunselman, N. Icitovic Tiotropium bromide step-up therapy for adults with uncontrolled asthma N Engl J Med 363 2010 1715 1726
44. S.E. Erickson, C. Iribarren, I.V. Tolstykh, P.D. Blanc, M.D. Eisner Effect of race on asthma management and outcomes in a large, integrated managed care organization Arch Intern Med 167 2007 1846 1852
45. W.C. Tan, C.J. Lamm, Y.Z. Chen Effectiveness of early budesonide intervention in Caucasian versus Asian patients with asthma: 3-year results of the START study Respirology 11 2006 767 775
46. M. Kawai, R. Kempsford, T. Pullerits Comparison of the efficacy of salmeterol/fluticasone propionate combination in Japanese and Caucasian asthmatics Respir Med 101 2007 2488 2494
47. J. Lötvall, L. Ekerljung, B. Lundbäck Multi-symptom asthma is closely related to nasal blockage, rhinorrhea and symptoms of chronic rhinosinusitis: evidence from the West Sweden Asthma Study Respir Res 11 2010 163
48. K.F. Rabe, M. Adachi, C.K.W. Lai Worldwide severity and control of asthma in children and adults: The global asthma insights and reality surveys J Allergy Clin Immunol 114 2004 40 47
49. M. Cazzola, M.G. Matera Novel long-acting bronchodilators for COPD and asthma Br J Pharmacol 155 2008 291 299
50. S.W. Stoloff, D.A. Stempel, J. Meyer, R.H. Stanford, J.R. Carranza Rosenzweig Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies J Allergy Clin Immunol 113 2004 245 251
51. M.P. Sovani, C.I. Whale, J. Oborne Poor adherence with inhaled corticosteroids for asthma: can using a single inhaler containing budesonide and formoterol help? Br J Gen Pract 58 2008 37 43