Assessment of specific immunotherapy efficacy using a novel placebo score-based method

Annals of Allergy, Asthma and Immunology

Volumn 109, Issue 5, 2012, Pages

  Frew, Anthony J ^a   Dubuske, Lawrence ^b   Keith, Paul K ^c   Corrigan, Christopher J ^d   Aberer, Werner ^e   Fischer Von Weikersthal Drachenberg, Karl J ^f,g  

^a ROYAL SUSSEX COUNTY HOSPITAL   (United Kingdom)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^c Immunology Research Institute of New England   (United States)

^d MCMASTER UNIVERSITY   (Canada)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f MEDICAL UNIVERSITY OF GRAZ   (Austria)

^g Allergy Therapeutics   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; POLLEN ANTIGEN;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DRUG DOSE ESCALATION; DRUG EFFICACY; GRASS POLLEN; HUMAN; IMMUNOTHERAPY; MULTICENTER STUDY (TOPIC); PATIENT ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RETROSPECTIVE STUDY; RISK BENEFIT ANALYSIS; SCORING SYSTEM; SYMPTOMATOLOGY; TREATMENT DURATION; TREATMENT OUTCOME;

EID: 84867509332     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/j.anai.2012.08.013     Document Type: Article

References (17)

1. M. Benninger, J.R. Ferrar, M. Blaiss Evaluating approved medications to treat allergic rhinitis in the United States: an evidence-based review of efficacy for nasal symptoms by class Ann Allergy Asthma Immunol 104 2010 13 29
2. M.S. Blaiss Cognitive, social and economic costs of allergic rhinitis Allergy Asthma Proc 21 2000 7 13
3. R. Dahl, P.S. Anderson, T. Chivato, E. Valovirta, J. de Monchy National prevalence of respiratory allergic disorders Respir Med 98 2004 398 403
4. J. Bousquet, N. Khaltaev, A.A. Cruz Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen) Allergy 63 2008 8 160
5. I. Finegold, R.J. Dockhorn, D. Ein Immunotherapy throughout the decades: from Noon to now Ann Allergy Asthma Immunol 105 2010 328 337
6. L. Cox, R.E. Esch, M. Corbett Allergen immunotherapy practice in the United States: guidelines, measures and outcomes Ann Allergy Asthma Immunol 107 2011 289 300
7. Committee for Medicinal Products for Human Use (CHMP) Guideline on the clinical development of products for specific immunotherapy for the treatment of allergic disease European Medical Agency 2007 doc CHMP/EWP/18504/2006
8. D. Dalan, K. Brohaugh Relationships between ragweed (RW) sensitive patients' rhinitis outcomes questionnaire, residence and RW pollen counts J Allergy Clin Immunol 121 suppl 1 2008 S22
9. E. Fenstad, D. Dalan Distance relationships between the Fargo NAB counting station grass pollen counts and grass allergic patient symptom scores Poster presented at AAAAI 2008
10. A. Didier, H.-J. Malling, M. Worm Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5-grass pollen tablet for seasonal allergic rhinitis J Allergy Clin Immunol 120 2007 1338 1345
11. O. Pfaar, D.S. Robinson, A. Sager, R. Emuzyte Immunotherapy with depigmented-polymerized mixed tree pollen extract: a clinical trial and responder analysis Allergy 65 2010 1614 1621
12. L. DuBuske, A.J. Frew, F. Horak Ultra-short specific immunotherapy successfully treats seasonal allergic rhinoconjunctivitis to grass pollen Allergy Asthma Proc 32 2011 239 247
13. J. Kuehr, J. Brauburger, S. Zielen Efficacy of combination treatment with anti-IgE plus specific immunotherapy in polysensitized children and adolescents with seasonal allergic rhinitis J Allergy Clin Immunol 109 2002 274 280
14. M.H. Shamji, S.R. Durham Mechanisms of immunotherapy to aeroallergens Clin Exp Allergy 41 2011 1235 1246
15. R. Dahl, A. Kapp, G. Colombo Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allergic rhinoconjunctivitis J Allergy Clin Immunol 118 2006 434 440
16. P.E. Taylor, H. Jonsson Thunderstorm asthma Curr Allergy Asthma Rep 4 2004 409 413
17. J.T.M. Buters, I. Weichenmeier, S. Ochs The allergen Bet v 1 in fractions of ambient air deviates from birch pollen counts Allergy 65 2010 850 858