A virus-like particle vaccine for coxsackievirus A16 potently elicits neutralizing antibodies that protect mice against lethal challenge

Vaccine

Volumn 30, Issue 47, 2012, Pages 6642-6648

  Liu, Qingwei ^a   Yan, Kexia ^a   Feng, Yanfang ^a   Huang, Xulin ^a   Ku, Zhiqiang ^a   Cai, Yicun ^a   Liu, Fei ^a   Shi, Jinping ^a   Huang, Zhong ^a  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

Author keywords

Coxsackievirus A16; Neutralization; Passive immunization; Virus like particle

Indexed keywords

ANTIBODY; BACULOVIRUS VECTOR; NEUTRALIZING ANTIBODY; VIRUS VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BIOPHYSICS; CONTROLLED STUDY; COXSACKIE VIRUS A; ELECTRON MICROSCOPY; ENZYME LINKED IMMUNOSPOT ASSAY; FEMALE; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; LETHALITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; VIRUS PARTICLE; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CERCOPITHECUS AETHIOPS; ENTEROVIRUS; FEMALE; HAND, FOOT AND MOUTH DISEASE; IMMUNIZATION, PASSIVE; MICE; MICE, INBRED ICR; NEUTRALIZATION TESTS; SF9 CELLS; VACCINES, VIRUS-LIKE PARTICLE; VERO CELLS; VIRAL VACCINES;

EID: 84867482187     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.08.071     Document Type: Article

References (24)

1. Wong S.S., Yip C.C., Lau S.K., Yuen K.Y. Human enterovirus 71 and hand, foot and mouth disease. Epidemiol Infect 2010, 138(August (8)):1071-1089.
2. Chatproedprai S., Theanboonlers A., Korkong S., Thongmee C., Wananukul S., Poovorawan Y. Clinical and molecular characterization of hand-foot-and-mouth disease in Thailand, 2008-2009. Jpn J Infect Dis 2010, 63(July (4)):229-233.
3. Tu P.V., Thao N.T., Perera D., Huu T.K., Tien N.T., Thuong T.C., et al. Epidemiologic and virologic investigation of hand, foot, and mouth disease, southern Vietnam, 2005. Emerg Infect Dis 2007, 13(November (11)):1733-1741.
4. Ang L.W., Koh B.K., Chan K.P., Chua L.T., James L., Goh K.T. Epidemiology and control of hand, foot and mouth disease in Singapore, 2001-2007. Ann Acad Med Singapore 2009, 38(February (2)):106-112.
5. Li L., He Y., Yang H., Zhu J., Xu X., Dong J., et al. Genetic characteristics of human enterovirus 71 and coxsackievirus A16 circulating from 1999 to 2004 in Shenzhen, People's Republic of China. J Clin Microbiol 2005, 43(August (8)):3835-3839.
6. Hosoya M., Kawasaki Y., Sato M., Honzumi K., Hayashi A., Hiroshima T., et al. Genetic diversity of coxsackievirus A16 associated with hand, foot, and mouth disease epidemics in Japan from 1983 to 2003. J Clin Microbiol 2007, 45(January (1)):112-120.
7. Zhang Y., Tan X.J., Wang H.Y., Yan D.M., Zhu S.L., Wang D.Y., et al. An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China. J Clin Virol 2009, 44(April (4)):262-267.
8. McMinn P.C. An overview of the evolution of enterovirus 71 and its clinical and public health significance. FEMS Microbiol Rev 2002, 26(March (1)):91-107.
9. Yang F., Zhang T., Hu Y., Wang X., Du J., Li Y., et al. Survey of enterovirus infections from hand, foot and mouth disease outbreak in China, 2009. Virol J 2011, 8:508.
10. Solomon T., Lewthwaite P., Perera D., Cardosa M.J., McMinn P., Ooi M.H. Virology, epidemiology, pathogenesis, and control of enterovirus 71. Lancet Infect Dis 2010, 10(November (11)):778-790.
11. Xu J., Qian Y., Wang S., Serrano J.M., Li W., Huang Z., et al. EV71: an emerging infectious disease vaccine target in the Far East?. Vaccine 2010, 28(April (20)):3516-3521.
12. Lee M.S., Chang L.Y. Development of enterovirus 71 vaccines. Expert Rev Vaccines 2010, 9(February (2)):149-156.
13. Wang C.Y., Li Lu F., Wu M.H., Lee C.Y., Huang L.M. Fatal coxsackievirus A16 infection. Pediatr Infect Dis J 2004, 23(March (3)):275-276.
14. Wright H.T., Landing B.H., Lennette E.H., Mc A.R. Fatal infection in an infant associated with Coxsackie virus group A, type 16. N Engl J Med 1963, 268(May):1041-1044.
15. Goldberg M.F., McAdams A.J. Myocarditis possibly due to Coxsackie group A, type 16, virus. J Pediatr 1963, 62(May):762-765.
16. Xu W., Liu C.F., Yan L., Li J.J., Wang L.J., Qi Y., et al. Distribution of enteroviruses in hospitalized children with hand, foot and mouth disease and relationship between pathogens and nervous system complications. Virol J 2012, 9(1):8.
17. Noad R., Roy P. Virus-like particles as immunogens. Trends Microbiol 2003, 11(September (9)):438-444.
18. Chackerian B. Virus-like particles: flexible platforms for vaccine development. Expert Rev Vaccines 2007, 6(June (3)):381-390.
19. Chung Y.C., Ho M.S., Wu J.C., Chen W.J., Huang J.H., Chou S.T., et al. Immunization with virus-like particles of enterovirus 71 elicits potent immune responses and protects mice against lethal challenge. Vaccine 2008, 26(March (15)):1855-1862.
20. Wu Z., Gao Y., Sun L., Tien P., Jin Q. Quick identification of effective small interfering RNAs that inhibit the replication of coxsackievirus A16. Antiviral Res 2008, 80(December (3)):295-301.
21. Yang F., Jin Q., He Y., Li L., Hou Y. The complete genome of Enterovirus 71 China strain. Sci China C Life Sci 2001, 44(April (2)):178-183.
22. Reed L.J.M.H. A simple method of estimating 50 percent endpoints. Am J Hyg 1938, 27:493-499.
23. Liu Q., Ku Z., Cai Y., Sun B., Leng Q., Huang Z. Detection, characterization and quantitation of coxsackievirus A16 using polyclonal antibodies against recombinant capsid subunit proteins. J Virol Methods 2011, 173(April (1)):115-120.
24. Chung C.Y., Chen C.Y., Lin S.Y., Chung Y.C., Chiu H.Y., Chi W.K., et al. Enterovirus 71 virus-like particle vaccine: improved production conditions for enhanced yield. Vaccine 2010, 28(October (43)):6951-6957.