Implementation of Xpert MTB/RIF for routine point-of-care diagnosis of tuberculosis at the primary care level

South African Medical Journal

Volumn 102, Issue 10, 2012, Pages 805-807

  Clouse, Kate ^a,b   Page Shipp, Liesl ^c   Dansey, Heather ^d   Moatlhodi, Bridgette ^c   Scott, Lesley ^e,f   Bassett, Jean ^d   Stevens, Wendy ^e,f   Sanne, Ian ^a,c   Van Rie, Annelies ^b  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b IL   (United States)

^c RIGHT TO CARE   (South Africa)

^d Witkoppen Health and Welfare Centre   (South Africa)

^e NATIONAL HEALTH LABORATORY SERVICE   (South Africa)

^f UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

RIFAMPICIN;

ANTIBIOTIC RESISTANCE; ARTICLE; DIAGNOSTIC TEST; EARLY DIAGNOSIS; HEALTH CARE MANAGEMENT; HOSPITAL SERVICE; HUMAN; LABORATORY DEVICE; MEDICAL DOCUMENTATION; POINT OF CARE TESTING; PRIMARY HEALTH CARE; QUALITY CONTROL; RESOURCE MANAGEMENT; TUBERCULOSIS; WORK ENVIRONMENT; XPERT TEST;

HIV INFECTIONS; HUMANS; MYCOBACTERIUM TUBERCULOSIS; NUCLEIC ACID AMPLIFICATION TECHNIQUES; OUTPATIENT CLINICS, HOSPITAL; POINT-OF-CARE SYSTEMS; PRIMARY HEALTH CARE; SOUTH AFRICA; TUBERCULOSIS, MULTIDRUG-RESISTANT; TUBERCULOSIS, PULMONARY;

EID: 84867463864     PISSN: 02569574     EISSN: None     Source Type: Journal    
DOI: 10.7196/SAMJ.5851     Document Type: Article

References (9)

1. World Health Organization. Roadmap for rolling out Xpert MTB/RIF for rapid diagnosis of TB and MDR-TB. Geneva: 8 Dec 2010. http://www.who.int/tb/laboratory/roadmap_xpert_mtb-rif.pdf (accessed 22 March 2012).
2. Meyer-Rath G, Bistline K, Long L, et al. The incremental cost of introducing Xpert MTB/RIF into the South African national tuberculosis programme: Results of the National TB Cost Model 2011/12-2016/17. Health Economics and Epidemiology Research Office. July 2011. http://www.bu.edu/cghd/ files/2011/07/HERO_Policy_Brief_No_1-National_TB_Cost_Model_South_Africa_July_20111.pdf (accessed 22 March 2012).
3. Van Rie A, Page-Shipp L, Scott L, Sanne I, Stevens W. Xpert MTB/RIF for point-of-care diagnosis of TB in high-HIV burden, resource-limited countries: hype or hope? Expert Rev Mol Diagn 2010;10(7):937-946.
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6. Cepheid. Xpert MTB/RIF brochure (CGXMTB/RIF-10; 300-7810 Rev A). (Apr 2009). http:// tbevidence.org/documents/rescentre/sop/XpertMTB_Broch_R9_EU.pdf (accessed 22 March 2012).
7. World Health Organization. Rapid implementation of the Xpert MTB/RIF diagnostic test. 2011. http:// whqlibdoc.who.int/publications/2011/9789241501569_eng.pdf (accessed 22 March 2012).
8. Boehme CC, Nicol MP, Nabeta P, et al. Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study. Lancet 2011;377(9776):1495-1505.
9. Scott LE, McCarthy K, Gous N, et al. Comparison of Xpert MTB/RIF with other nucleic acid technologies for diagnosing pulmonary tuberculosis in a high HIV prevalence setting: a prospective study. PLoS Med 2011;8(7):e1001061. [http://dx.doi.org/10.1371/journal.pmed.1001061]