Cochleates Derived from Vibrio cholerae O1 Proteoliposomes: The Impact of Structure Transformation on Mucosal Immunisation

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Acevedo, Reinaldo ^a   Pérez, Oliver ^a   Zayas, Caridad ^a   Pérez, José L ^a   Callicó, Adriana ^a   Cedré, Bárbara ^a   García, Luis ^a   Mckee, David ^b   Mullen, Alexander B ^b   Ferro, Valerie A ^b  

^a FINLAY INSTITUTE   (Cuba)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT FINLAY COCHLEATE 2; ANTIGEN; CALCIUM CHELATING AGENT; EDETIC ACID; OVALBUMIN; PHOSPHOLIPID DERIVATIVE; PROTEOLIPOSOME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG PENETRATION; EPIFLUORESCENCE MICROSCOPY; FEMALE; FREEZE FRACTURE; FREEZE FRACTURE ELECTRON MICROSCOPY; IMMUNIZATION; IN VITRO STUDY; IN VIVO STUDY; MICROSCOPY; MOUSE; NONHUMAN; PROTEIN UNFOLDING; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; VIBRIO CHOLERAE;

ANIMALS; CALCIUM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FREEZE FRACTURING; IMMUNITY, MUCOSAL; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; PHOSPHOLIPIDS; PROTEOLIPIDS; VIBRIO CHOLERAE;

EID: 84867418343     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046461     Document Type: Article

References (23)

1. Papahadjopoulos D, Vail WJ, Jacobson K, Poste G, (1975) Cochleate lipid cylinders: Formation of unilamellar lipid vesicles. Biochim Biophys Acta 394: 438-491.
2. Gould-Fogerite S, Kheiri MT, Zhang F, Wang Z, Scolpino AJ, et al. (1998) Targenting immune response induction with cochleate and liposome based vaccines. Advanced Drug Delivery Reviews 32: 273-287.
3. Zarif L, (2002) Elongated supramolecular assemblies in drug delivery. Journal of Controlled Release 81: 7-23.
4. Pérez O, Bracho G, Lastre M, Sierra G, Campa C, et al. (2008) Method of obtaining cochlear structures, vaccine compositions, adjuvants and intermediates thereof. WIPO, WO/2004/047805. Granted by Cuban Office for Intellectual Property OCPI23313.
5. Pérez O, Lastre M, Cabrera O, del Campo J, Bracho G, et al. (2007) New vaccines require potent adjuvants like AFPL1 and AFCo1. Scandinavian Journal of Immunology 66: 271-277.
6. Acevedo R, Callicó A, del Campo J, González E, Cedré B, et al. (2009) Intranasal administration of proteoliposome-derived cochleates from Vibrio cholerae O1 induce mucosal and systemic immune responses in mice. Methods 49: 309-315.
7. Qu X, Wei W, Gray AI, Tetley L, Uchegbu IF, (2004) Self-assembly of cetyl linear polyethylenimine to give micelles, vesicles, and dense nanoparticles. Macromolecules 37: 9114-9122.
8. Yuki Y, Kiyono H, (2009) Mucosal vaccines: novel advances in technology and delivery. Expert Rev. Vaccines 8: 1083-1097.
9. Alcon V, Baca-Estrada M, Vega-Lopez M, Wilson P, Babiuk LA, et al. (2005) Mucosal delivery of bacterial antigens and CpG oligonucleotides formulated in biphasic lipid vesicles in pigs. AAPS Journal 7: E566-E571.
10. Ryan EJ, Daly LM, Mills KHG, (2001) Immunomodulators and delivery systems for vaccination by mucosal routes. Trends in Biotechnology 19: 293-304.
11. Saptarshi P, Chaudhuria K, Chatterjee AN, Das J, (1992) Presence of exposed phospholipids in the outer membrane of Vibrio cholerae. Journal of General Microbiology 138: 755-61.
12. Giles DK, Hankins JV, Guan Z, Trent MS, (2011) Remodelling of the Vibrio cholerae membrane by incorporation of exogenous fatty acids from host and aquatic environments. Mol Microbiol 79: 716-28.
13. Meyer HW, Semmler K, Rettig W, Pohle W, Ulrich AS, et al. (2000) Hydration of DMPC and DPPC produces a novel subgel phase with convex-concave bilayer curvatures. Chem Phys Lipids 105: 149-166.
14. Garidel P, Richter W, Rapp G, Blume A, (2001) Structural and morphological investigations of the formation of quasi-crystalline phases of 1,2-dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG). Phys Chem Chem Phys 3: 1504-1513.
15. Marone PA, Elsmore SK, Sandulow J, Mannino RJ, (2005) Structural determinants of divalent cation-induced phosphatidylserine cochleate crystallization. Microsc Microanal 11: 1244-1245.
16. Leng J, Egelhaaf SU, Cates ME, (2003) Kinetics of the micelle-to-vesicle transition: Aqueous lecithin-bile salt mixtures. Biophysical Journal 85: 1624-1646.
17. Davis SS, Illum L, (2003) Absorption enhancers for nasal drug delivery. Clin Pharmacokinet 42: 1107-1128.
18. Lewis D (2008) Mucosal Adjuvants. UK: St George's Vaccine Institute. Available: www.who.int/vaccineresearch/about/gvrf/Lewis.pdf.
19. Rimoldi M, Rescigno M, (2005) Uptake and presentation of orally administered antigens. Vaccine 23: 1793-1796.
20. Borges O, Lebre F, Bento D, Borchard G, Junginger HE, (2010) Mucosal Vaccines: Recent Progress in Understanding the Natural Barriers. Pharmaceutical Research 27: 211-23.
21. Mann JFS, Acevedo R, del Campo J, Perez O, Ferro VA, (2009) Delivery systems: a vaccine strategy for overcoming mucosal tolerance? Expert Rev Vaccines 8: 103-112.
22. Brewer JM, Pollock KGJ, Tetley L, Russell DG, (2004) Vesicle size influences the trafficking, processing, and presentation of antigens in lipid vesicles. Journal of Immunology 173: 6143-50.
23. Pérez JL, González Y, Año G, Cedré B, Valmaseda T, et al. (2006) Obtaining Vibrio cholerae 01 outer membrane extracts with different detergents. VacciMonitor 15: 1-7.