Effect of ginseng polysaccharide on the urinary excretion of type 2 diabetic rats studied by liquid chromatography-mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 907, Issue , 2012, Pages 7-12

  Niu, Jun ^a,b   Pi, Zifeng ^a   Yue, Hao ^c   Wang, Yang ^c   Yu, Qing ^a,b   Liu, Shuying ^a,c  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c CHANGCHUN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Metabolomics; RRLC MS; Type 2 diabetes; Water soluble ginseng polysaccharide

Indexed keywords

DIABETIC RATS; DNA METABOLISM; EFFECT MECHANISM; ENERGY METABOLISM; FATTY ACID METABOLISM; IN-VIVO; INOSINE; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; MECHANISM OF ACTION; METABOLOMICS; RRLC/MS; STEROID HORMONE; TETRAHYDROCORTISOL; TYPE-2 DIABETES; URINARY EXCRETION;

AMINO ACIDS; CHROMATOGRAPHY; FATTY ACIDS; PATTERN RECOGNITION; PHYSIOLOGY; PRINCIPAL COMPONENT ANALYSIS; RATS;

METABOLISM;

1 METHYLADENINE; CARBOXYLIC ACID; GINSENG POLYSACCHARIDE; GLUCONIC ACID; GLUCOSE; GLYCINE DERIVATIVE; INOSINE; SEBACIC ACID; SEROTONIN; TETRAHYDROCORTISOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA METABOLISM; DRUG EFFECT; ENERGY METABOLISM; FATTY ACID METABOLISM; GINSENG; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; LIPID METABOLISM; MALE; MASS SPECTROMETRY; METABOLISM; METABOLOMICS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEIC ACID METABOLISM; PATTERN RECOGNITION; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PURINE METABOLISM; RAT; STEROID METABOLISM; STREPTOZOCIN DIABETES; TRYPTOPHAN METABOLISM; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; URINARY EXCRETION;

ANIMALS; CHROMATOGRAPHY, REVERSE-PHASE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; MALE; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; PANAX; PLANT EXTRACTS; PLANT ROOTS; POLYSACCHARIDES; RATS; RATS, WISTAR; URINE;

PANAX GINSENG; RATTUS;

EID: 84867400861     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.08.012     Document Type: Article

References (25)

1. World Health Organization Prevention of diabetes mellitus, Technical Report Series no. 844, World Health Organization, Geneva, 1994.
2. International Diabetes Federation, Diabetes Atlas 2006, International Diabetes Federation, Brussels, Belgium. 3rd ed.
3. Hui H.X., Tang G., Go V.L.W. Chin. Med. 2009, 4:11.
4. Gupta R.K., Kesari A.N., Murthy P.S., Chandra R., Tandon V., Watal G. J. Ethnopharmacol. 2005, 99:75.
5. Xie J.T., Wu J.A., Mehendale S., Aung H.H., Yuan C.S. Phytomedicine 2004, 11:182.
6. Kwak Y.S., Kyung J.S., Kim J.S., Cho J.Y., Rhee M.H. Biol. Pharm. Bull. 2010, 33:468.
7. Yang M., Wang B.X., Jin Y.L., Wang Y., Cui Z.Y. Acta Pharmacol. Sin. 1990, 11:520.
8. Yang M., Wang B.X. Acta Pharmacol. Sin. 1991, 12:272.
9. Nicholson J.K., Lindon J.C., Holmes E. Xenobiotica 1999, 29:1181.
10. Gu Y., Zhang Y., Shi X., Li X., Hong J., Chen J., Gu W., Lu X., Xu G., Ning G. Talanta 2010, 81:766.
11. Cai S., Huo T.G., Xu J.H., Lu X.M., Zheng S.N., Li F.M. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2009, 877:3619.
12. Zhao X.J., Zhang Y., Meng X.L., Yin P.Y., Deng C., Chen J., Wang Z., Xu G.W. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2008, 873:151.
13. Tuitoek P.J., Ziari S., Tsin A., Rajotte R.V., Suh M.Y., Basu T.K. Br. J. Nutr. 1996, 75:615.
14. Wood R.D., Mitchell M., Sgouros J., Lindahl T. Science 2001, 291:1284.
15. Falnes P.O. Nucleic Acids Res. 2004, 32:6260.
16. Kassel D.B., Martin M., Schall W., Sweeley C.C. Biomed. Environ. Mass Spectrom. 1986, 13:535.
17. Bultitude F.W., Newham S.J. Clin. Chem. 1975, 21:1329.
18. Niwa T., Maeda K., Ohki T., Saito A., Tsuchida I. J. Chromatogr. 1981, 225:1.
19. Greco A.V., Mingrone G., Capristo E., Benedetti G., De Gaetano A., Gasbarrini G. Nutrition. 1998, 14:351.
20. Mabley J.G., Rabinovitch A., Suarez-Pinzon W., Hasko G., Pacher P., Power R., Southan G., Salzman A., Szabo C. Mol. Med. 2003, 9:96.
21. Trulson M.E., Himmel C.D. J. Neurochem. 1985, 44:1873.
22. Zhen Y., Krausz K.W., Chen C., Idle J.R., Gonzalez F.J. Mol. Endocrinol. 2007, 21:2136.
23. Kota B.P., Huang T.H., Roufogalis B.D. Pharmacol. Res. 2005, 51:85.
24. Peters J.M., Cheung C., Gonzalez F.J. J. Mol. Med. (Berl.) 2005, 83:774.
25. Chiodini I., Adda G., Scillitani A., Coletti F., Morelli V., Di Lembo S., Epaminonda P., Masserini B., Beck-Peccoz P., Orsi E., Ambrosi B., Arosio M. Diabetes Care 2007, 30:83.