Strategic assay deployment as a method for countering analytical bottlenecks in high throughput process development: Case studies in ion exchange chromatography

Biotechnology Progress

Volumn 28, Issue 5, 2012, Pages 1292-1302

  Konstantinidis, Spyridon ^a   Heldin, Eva ^b   Chhatre, Sunil ^a   Velayudhan, Ajoy ^a   Titchener Hooker, Nigel ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GE Healthcare Life Sciences   (Sweden)

Author keywords

Analytical bottleneck; Anion exchange chromatography; High throughput process development; Method comparison; Multicriteria decision making

Indexed keywords

ANALYTICAL BOTTLENECK; ANION EXCHANGE CHROMATOGRAPHY; METHOD COMPARISON; MULTI CRITERIA DECISION MAKING; PROCESS DEVELOPMENT;

CHROMATOGRAPHIC ANALYSIS; ESCHERICHIA COLI; LIQUID CHROMATOGRAPHY; PH EFFECTS;

THROUGHPUT;

ANION EXCHANGE RESIN; GREEN FLUORESCENT PROTEIN;

ADSORPTION; ARTICLE; BIOTECHNOLOGY; CHEMICAL ANALYSIS; CHEMISTRY; ESCHERICHIA COLI; EVALUATION; GENETICS; INSTRUMENTATION; ION EXCHANGE CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; PH;

ADSORPTION; ANION EXCHANGE RESINS; BIOTECHNOLOGY; CHEMISTRY TECHNIQUES, ANALYTICAL; CHROMATOGRAPHY, ION EXCHANGE; ESCHERICHIA COLI; GREEN FLUORESCENT PROTEINS; HYDROGEN-ION CONCENTRATION;

ESCHERICHIA COLI;

EID: 84867400118     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1591     Document Type: Article

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