Reproducibility and robustness of metabolome analysis in rat plasma of 28-day repeated dose toxicity studies

Toxicology Letters

Volumn 215, Issue 2, 2012, Pages 143-149

  Kamp, H ^a   Strauss, V ^a   Wiemer, J ^b   Leibold, E ^a   Walk, T ^b   Mellert, W ^a   Looser, R ^b   Prokoudine, A ^b   Fabian, E ^a   Krennrich, G ^a   Herold, M ^b   van Ravenzwaay, B ^a  

^a BASF SE   (Germany)

^b Metanomics GmbH   (Germany)

Author keywords

Metabolite profiling; Metabolomics; Mode of action; Rat; Reproducibility; Validation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; METABOLOME; METABOLOMICS; NONHUMAN; PLASMA; PRIORITY JOURNAL; RAT; TOXICOLOGY;

ANIMALS; BLOOD CHEMICAL ANALYSIS; FEMALE; MALE; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; RATS; RATS, INBRED WF; STATISTICS, NONPARAMETRIC; TOXICITY TESTS;

RATTUS;

EID: 84867384668     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.09.015     Document Type: Article

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