Optimization of sample preparation and a quadrupole ICP-MS measurement protocol for the determination of elemental impurities in pharmaceutical substances in compliance with USP guidelines

Journal of Analytical Atomic Spectrometry

Volumn 27, Issue 11, 2012, Pages 1909-1919

  Vanhaecke, F ^a   Van Hoecke, K ^a   Catry, C ^b  

^a GHENT UNIVERSITY   (Belgium)

^b JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTE CONCENTRATION; ANALYTICAL PROCEDURE; AQUA REGIA; AQUEOUS DISSOLUTION; AQUEOUS MEDIUM; BROAD SPECTRUM; COLLISION-REACTION CELL; ELEMENTAL IMPURITIES; HEXAPOLE; IMPURITY CONCENTRATION; LIMITS OF DETECTION; MEASUREMENT PROTOCOL; MICROWAVE-ASSISTED ACID DIGESTION; PARENTERAL ADMINISTRATION; PHARMACEUTICAL EXCIPIENT; POLYATOMIC INTERFERENCES; QUADRUPOLES; RELATIVE STANDARD DEVIATIONS; SAMPLE PREPARATION; SAMPLE PREPARATION PROCEDURE; SPIKE RECOVERY; STANDARD ADDITION; UNITED STATES PHARMACOPEIAS;

DISSOLUTION; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; MANGANESE; MASS SPECTROMETERS; NITRIC ACID; OPTIMIZATION; OSMIUM;

IMPURITIES;

EID: 84867380969     PISSN: 02679477     EISSN: 13645544     Source Type: Journal    
DOI: 10.1039/c2ja30128h     Document Type: Article

References (15)

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