Cardiovascular and metabolic problems in Turner's syndrome patients

Archives of Perinatal Medicine

Volumn 18, Issue 1, 2012, Pages 47-52

  Czyzyk, Adam ^a   Mȩczekalski, Błazej ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Cardiovascular diseases; Diabetes; Heart defects; Turner syndrome

Indexed keywords

EID: 84867374213     PISSN: 15050580     EISSN: 15084868     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Turner H.H. (1938) A syndrome of infantilism, congenital webbed neck and cubitus valgus. Endocrinology 23: 566-74.
2. Bondy C.A. (2007) Care of girls and women with Turner syndrome: A Guideline of the Turner Syndrome Study Group. J. Clin. Endocrinol. Metab. 92: 10-25.
3. Gravholt C.H. (2004) Epidemiological, endocrine and metabolic features in Turner syndrome. Eur. J. Endocrinol. 151: 657-87.
4. Mazzanti L., Prandstraller D., Tassinari D. et al. (1998) Heart diseases in Turner's syndrome. Helv. Paediatr. Acta. 43: 25-31.
5. Elsheikh M., Dunger D.B., Conway G.S. et al. (2002) Turner's syndrome in adulthood. Endocr. Rev. 23: 120-40.
6. Lacro R.V., Jones K.L., Benirschke K. (1988) Coarctation of the aorta in Turner syndrome: a pathologic study of fetuses with nuchal cystic hygromas, hydrops fetalis, and female genitalia. Pediatrics 81: 445-451.
7. Surerus E., Huggon I.C., Allan L.D. (2003) Turner's syndrome in fetal life. Ultrasound. Obstet. Gynecol. 22: 264-7
8. Clark E.B. (1984) Neck web and congenital heart defects: a pathogenic association in 45 X-O Turner syndrome. Teratology 29: 355-361.
9. Sybert V. (1998) Cardiovascular malformations and complications in Turner syndrome. Pediatrics 101: 1-7.
10. Völkl T.M., Degenhardt K., Koch A. et al. (2005) Cardiovascular anomalies in children and young adults with Ulrich? Turner syndrome the Erlangen experience. Clin. Cardiol. 28: 88-92.
11. Poprawski K, Michalski M, Ławniczak M et al. (2009) Cardiovascular abnormalities in patients with Turner syndrome according to karyotype: own experience and literature review. Pol. Arch. Med. Wewn. 119(7-8): 453-60.
12. Loscalzo M.L., Van P.L., Ho V.B. et al. (2005) Association between fetal lymphedema and congenital cardiovascular defects in Turner syndrome. Pediatrics 115: 732-5.
13. Ho V.B., Bakalov V.K., Cooley M. et al. (2004) Major vascular anomalies in Turner syndrome. Circulation 110: 1694-700.
14. Douchin S., Rossignol A.M., Klein S.K. et al. (2000) Heart malformations and vascular complications associated with Turner's syndrome. Prospective study of 26 patients. Arch. Mal. Coeur. Vaiss. 93: 565-70.
15. Robbins C.L., Dietz P.M., Bombard J. et al. (2011). Lifestyle interventions for hypertension and dyslipidemia among women of reproductive age. Prev. Chronic. Dis., 8(6): A123.
16. Nofer J.R. (2012) Estrogens and atherosclerosis: insights from animal models and cell systems. J. Mol. Endocrinol. 48(2): R13-29.
17. Gravholt C.H., Naeraa R.W., Nyholm B. et al. (1998) Glucose metabolism, lipid metabolism and cardiovascular risk factors in adult Turner's syndrome: the impact of sex hormone replacement. Diabetes. Care. 21: 1062-70.
18. Nathwani N.C., Unwin R., Brook C.G. (2002) Blood pressure and Turner syndrome. Clin. Endo. 52: 363-70.
19. Elsheikh M., Bird R., Casadei B. et al. (2000) The effect of hormone replacement therapy on cardiovascular hemodynamics in women with Turner's syndrome. J. Clin. Endocrinol. Metab. 85: 614-8.
20. Giordano R., Forno D., Lanfranco F. et al. (2011) Metabolic and cardiovascular outcomes in a group of adult patients with Turner's syndrome under hormonal replacement therapy. Eur. J. Endocrinol. 164(5): 819-26.
21. Laurent S., Boutouyrie P., Asmar R. et al. (2001) Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension 37: 1236-41.
22. Mortensen K.H., Hansen K.W., Erlandsen M. et al. (2009) Ambulatory arterial stiffness index in Turner syndrome: the impact of sex hormone replacement therapy. Horm. Res. 72: 184-9.
23. Ostberg J.E., Donald A.E., Halcox J.P. et al. (2005) Vasculopathy in Turner syndrome: arterial dilatation and intimal thickening without endothelial dysfunction. J. Clin. Endocrinol. Metab. 90(9): 5161-6
24. Cheng K.S., Mikhailidis D.A., Hamilton G. et al. (2002). A review of carotid and femoral intima-media thickness as an indicator of the presence of vascular disease and cardiovascular risk factors. Cardiovasc. Res. 54: 528-38.
25. Price W.H., Clayton J.F., Collyer S. et al. (1986) Mortality ratios, life expectancy, and causes of death in patients with Turner'syndrome. J. Epidemiol. Comm. Health 40: 97-102.
26. A.E. Lin, B. Lippe, R.G. Rosenfeld (1998) Further delineation of aortic dilation, dissection, and rupture in patients with Turner syndrome. Pediatrics. 102: E12.
27. Matura L.A., Ho V.B., Rosing D.R. et al. (2007) Aortic dilatation and dissection in Turner syndrome. Circulation, 116: 1663-70.
28. Practice Committee of American Society For Reproductive Medicine (2012) Increased maternal cardiovascular mortality associated with pregnancy in women with Turner syndrome. Fertil. Steril. 97(2): 282-4.
29. Van P.L., Bakalov V.K., Bondy C.A. (2006) Monosomy for the X-chromosome is associated with an atherogenic lipid profile. J. Clin. Endocrinol. Metab. 91: 2867-70.
30. Cooley M., Bakalov V., Bondy C.A. (2003) Lipid profiles in women with 45,X vs 46,XX primary ovarian failure. JAMA. 290: 2127-8.
31. Mauras N., Shulman D., Hsiang H.Y. et al. (2007) Metabolic effects of oral versus transdermal estrogen in growth hormone-treated girls with Turner syndrome. J. Clin. Endocrinol. Metab. 92(11): 4154-60.
32. Van Pareren Y.K., Muinck Keizer-Schrama S.M.P.F., Stijnen T. et al. (2002) Effect of discontinuation of longterm growth hormone treatment on carbohydrate metabolism and risk factors for cardiovascular disease in girls with Turner syndrome. J. Clin. Endocrinol. Metab. 87: 5442-8.
33. Bannink E.M.N., Van der Palen R.L.F., Mulder P.G.H. et al. (2009) Long-term follow-up of GH-treated girls with Turner syndrome: metabolic consequences. Horm. Res. 71: 343-9.
34. Avruskin T.W., Crigler J.F. Jr., Soeldner J.S. (1979) Turner's syndrome and carbohydrate metabolism. I. Impaired insulin secretion after tolbutamide and glucagon stimulation tests: evidence of insulin deficiency. Am. J. Med. Sci. 77: 145-52.
35. Caprio S., Boulware S., Diamond M. et al. (1991) Insulin resistance: an early metabolic defect of Turner's syndrome. J. Clin. Endocrinol. Metab. 72: 832-36.
36. Bakalov V.K., Cooley M.M., Quon M.J. et al. (2004): Impaired insulin secretion in the Turner metabolic syndrome. J. Clin. Endocrinol. Metab. 89: 3516-20.
37. Gravholt C.H., Naeraa R.W., Brixen K. et al. (2002) Shortterm growth hormone treatment in girls with Turner syndrome decreases fat mass and insulin sensitivity: a randomized, doubleblind, placebo-controlled, crossover study. Pediatrics 110: 889-96.
38. Neufeld N.D., Lippe B., Sperling M.A. (1980) Carbohydrate intolerance in gonadal dysgenesis: a new model of insulin resistance. Diabetes 25(suppl): 379.
39. Gravholt C.H., Nyholm B., Saltin B. et al. (2001) Muscle fiber composition and capillary density in Turner syndrome: evidence of increased muscle fi ber size related to insulin resistance. Diab. Care. 24: 1668-73.
40. Landin-Wilhelmsen K., Bryman I., Wilhelmsen L. (2001) Cardiac malformations and hypertension, but not metabolic risk factors, are common in Turner syndrome. J. Clin. Endocrinol. Metab. 86: 4166-70.
41. Godsland I.F. (2005) Oestrogens and insulin secretion. Diabetologia 48: 2213-20.