N-cadherin expression in malignant germ cell tumours of the testis

BMC Clinical Pathology

Volumn 12, Issue , 2012, Pages

  Bremmer, Felix ^a   Hemmerlein, Bernhard ^a   Strauss, Arne ^a   Burfeind, Peter ^a   Thelen, Paul ^a   Radzun, Heinz Joachim ^a   Behnes, Carl Ludwig ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

Embryonal carcinoma; Immunohistochemistry; N cadherin; Seminoma; TGCT cell lines

Indexed keywords

MONOCLONAL ANTIBODY; NERVE CELL ADHESION MOLECULE;

ADULT; ARTICLE; CANCER SURGERY; CHORIONIC CARCINOMA; CYTOPLASM; EMBRYONAL CARCINOMA; GERM CELL TUMOR; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; ORCHIECTOMY; PROTEIN EXPRESSION; SEMINOMA; TERATOMA; YOLK SAC TUMOR;

EID: 84867370669     PISSN: None     EISSN: 14726890     Source Type: Journal    
DOI: 10.1186/1472-6890-12-19     Document Type: Article

References (36)

1. Global trends in testicular cancer incidence and mortality. Rosen A, Jayram G, Drazer M, Eggener SE, Eur Urol 2011 60 2 374 379 Epub 2011/05/27 10.1016/j.eururo.2011.05.004 21612857
2. Testicular germ-cell cancer. Horwich A, Shipley J, Huddart R, Lancet 2006 367 9512 754 765 Epub 2006/03/07 10.1016/S0140-6736(06)68305-0 16517276 (Pubitemid 43326294)
3. Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors. Hoei-Hansen CE, Nielsen JE, Almstrup K, Sonne SB, Graem N, Skakkebaek NE, et al. Clinical cancer research: an official journal of the American Association for Cancer Research 2004 10 24 8521 8530 Epub 2004/12/30 10.1158/1078-0432.CCR-04-1285 (Pubitemid 40053419)
4. The cadherin superfamily: diversity in form and function. Angst BD, Marcozzi C, Magee AI, J Cell Sci 2001 114 Pt 4 629 641 Epub 2001/02/15 11171368 (Pubitemid 32237135)
5. The cadherin-catenin system: implications for growth and differentiation of endocrine tissues. Potter E, Bergwitz C, Brabant G, Endocr Rev 1999 20 2 207 239 Epub 1999/04/16 10.1210/er.20.2.207 10204118 (Pubitemid 29339591)
6. Cadherins in development and cancer. Stemmler MP, Mol Biosyst 2008 4 8 835 850 Epub 2008/07/18 10.1039/b719215k 18633485 (Pubitemid 352009212)
7. Regulation of cadherin-mediated adhesion in morphogenesis. Gumbiner BM, Nat Rev Mol Cell Biol 2005 6 8 622 634 Epub 2005/07/19 16025097 (Pubitemid 41081266)
8. Beyond the epithelium: cadherin function in fibrous connective tissues. El Sayegh TY, Kapus A, McCulloch CA, FEBS Lett 2007 581 2 167 174 Epub 2007/01/16 10.1016/j.febslet.2006.12.029 17217950 (Pubitemid 46099007)
9. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Takeichi M, Development 1988 102 4 639 655 Epub 1988/04/01 3048970
10. The nonreceptor protein tyrosine phosphatase PTP1B binds to the cytoplasmic domain of N-cadherin and regulates the cadherin-actin linkage. Balsamo J, Arregui C, Leung T, Lilien J, J Cell Biol 1998 143 2 523 532 Epub 1998/10/24 10.1083/jcb.143.2.523 9786960 (Pubitemid 28487868)
11. N-cadherin is developmentally regulated and functionally involved in early hematopoietic cell differentiation. Puch S, Armeanu S, Kibler C, Johnson KR, Muller CA, Wheelock MJ, et al. J Cell Sci 2001 114 Pt 8 1567 1577 Epub 2001/04/03 11282032 (Pubitemid 32427842)
12. Immunohistochemistry in the distinction between malignant mesothelioma and pulmonary adenocarcinoma: a critical evaluation of new antibodies. Abutaily AS, Addis BJ, Roche WR, J Clin Pathol 2002 55 9 662 668 Epub 2002/08/27 10.1136/jcp.55.9.662 12194995 (Pubitemid 34970087)
13. Immunoreactivity for cadherins, HGF/SF, met, and erbB-2 in pleural malignant mesotheliomas. Thirkettle I, Harvey P, Hasleton PS, Ball RY, Warn RM, Histopathology 2000 36 6 522 528 Epub 2000/06/10 10.1046/j.1365-2559.2000.00888. x 10849094 (Pubitemid 30348777)
14. Differential expression of N-cadherin in pleural mesotheliomas and E-cadherin in lung adenocarcinomas in formalin-fixed, paraffin-embedded tissues. Han AC, Peralta-Soler A, Knudsen KA, Wheelock MJ, Johnson KR, Salazar H, Hum Pathol 1997 28 6 641 645 Epub 1997/06/01 10.1016/S0046-8177(97)90171-4 9190996 (Pubitemid 27258415)
15. Epithelial-type and neural-type cadherin expression in malignant noncarcinomatous neoplasms with epithelioid features that involve the soft tissues. Laskin WB, Miettinen M, Arch Pathol Lab Med 2002 126 4 425 431 Epub 2002/03/20 11900566 (Pubitemid 34286806)
16. Expression of E-cadherin and N-cadherin in surface epithelial-stromal tumors of the ovary distinguishes mucinous from serous and endometrioid tumors. Peralta Soler A, Knudsen KA, Tecson-Miguel A, McBrearty FX, Han AC, Salazar H, Hum Pathol 1997 28 6 734 739 Epub 1997/06/01 10.1016/S0046-8177(97)90184-2 9191009 (Pubitemid 27258428)
17. Cadherins and integrins in renal cell carcinoma: an immunohistochemical study. Markovic-Lipkovski J, Brasanac D, Muller GA, Muller CA, Tumori 2001 87 3 173 178 Epub 2001/08/16 11504373 (Pubitemid 32655965)
18. International Agency for Research on Cancer. Pathology and genetics of tumours of the urinary system and male genital organs. Eble JN, Lyon: IARC-Press 2004 359 p S p
19. Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryos. Hatta K, Takagi S, Fujisawa H, Takeichi M, Dev Biol 1987 120 1 215 227 Epub 1987/03/01 10.1016/0012-1606(87)90119-9 3817290 (Pubitemid 17027111)
20. Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA, J Cell Biol 2000 148 4 779 790 Epub 2000/02/23 10.1083/jcb.148.4. 779 10684258
21. EMT: when epithelial cells decide to become mesenchymal-like cells. Kalluri R, J Clin Invest 2009 119 6 1417 1419 Epub 2009/06/03 10.1172/JCI39675 19487817
22. Expression of epithelial-mesenchymal transition markers in renal cell carcinoma: impact on prognostic outcomes in patients undergoing radical nephrectomy. Harada KI, Miyake H, Kusuda Y, Fujisawa M, BJU Int 2012 Epub 2012/06/21
23. N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression. Nieman MT, Prudoff RS, Johnson KR, Wheelock MJ, J Cell Biol 1999 147 3 631 644 Epub 1999/11/05 10.1083/jcb.147.3.631 10545506 (Pubitemid 29523468)
24. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Polyak K, Weinberg RA, Nat Rev Cancer 2009 9 4 265 273 Epub 2009/03/06 10.1038/nrc2620 19262571
25. Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition. Thomson S, Buck E, Petti F, Griffin G, Brown E, Ramnarine N, et al. Cancer Res 2005 65 20 9455 9462 Epub 2005/10/19 10.1158/0008-5472.CAN-05-1058 16230409 (Pubitemid 41508014)
26. Distinct cadherin profiles in special variant carcinomas and other tumors of the breast. Han AC, Soler AP, Knudsen KA, Salazar H, Hum Pathol 1999 30 9 1035 1039 Epub 1999/09/24 10.1016/S0046-8177(99)90220-4 10492037 (Pubitemid 29427159)
27. Cadherin switching. Wheelock MJ, Shintani Y, Maeda M, Fukumoto Y, Johnson KR, J Cell Sci 2008 121 Pt 6 727 735 Epub 2008/03/07 18322269 (Pubitemid 351578108)
28. Involvement of E-cadherin and beta-catenin in germ cell tumours and in normal male fetal germ cell development. Honecker F, Kersemaekers AM, Molier M, Van Weeren PC, Stoop H, De Krijger RR, et al. J Pathol 2004 204 2 167 174 Epub 2004/09/21 10.1002/path.1614 15378486 (Pubitemid 39335290)
29. Expression of E-cadherin and catenins on testis tumor. Saito T, Katagiri A, Watanabe R, Tanikawa T, Kawasaki T, Tomita Y, et al. Urol Int 2000 65 3 140 143 Epub 2000/10/29 10.1159/000064859 11054031
30. The pluripotency homeobox gene NANOG is expressed in human germ cell tumors. Hart AH, Hartley L, Parker K, Ibrahim M, Looijenga LH, Pauchnik M, et al. Cancer 2005 104 10 2092 2098 Epub 2005/10/06 10.1002/cncr.21435 16206293 (Pubitemid 41579954)
31. Immunohistochemistry of germ cell and trophoblastic neoplasms. Niehans GA, Manivel JC, Copland GT, Scheithauer BW, Wick MR, Cancer 1988 62 6 1113 1123 Epub 1988/09/15 10.1002/1097-0142(19880915)62:6<1113::AID- CNCR2820620614>3.0.CO;2-0 2457424
32. A comparative morphological and immunohistochemical study of testicular seminomas and intracranial germinomas. Bentley AJ, Parkinson MC, Harding BN, Bains RM, Lantos PL, Histopathology 1990 17 5 443 449 Epub 1990/11/01 10.1111/j.1365-2559.1990.tb00766.x 2076869
33. CD30 and CD117 (c-kit) used in combination are useful for distinguishing embryonal carcinoma from seminoma. Leroy X, Augusto D, Leteurtre E, Gosselin B, The journal of histochemistry and cytochemistry: official journal of the Histochemistry Society 2002 50 2 283 285 Epub 2002/01/19 10.1177/ 002215540205000216 (Pubitemid 34106767)
34. OCT4 staining in testicular tumors: a sensitive and specific marker for seminoma and embryonal carcinoma. Jones TD, Ulbright TM, Eble JN, Baldridge LA, Cheng L, Am J Surg Pathol 2004 28 7 935 940 Epub 2004/06/30 10.1097/00000478- 200407000-00014 15223965 (Pubitemid 38856851)
35. The differential diagnosis of yolk sac tumor and seminoma. Usefulness of cytokeratin, alpha-fetoprotein, and alpha-1-antitrypsin immunoperoxidase reactions. Eglen DE, Ulbright TM, Am J Clin Pathol 1987 88 3 328 332 Epub 1987/09/01 2443003 (Pubitemid 17145598)
36. Germ cell tumors of the mediastinum and testis: a comparative immunohistochemical study of 120 cases. Suster S, Moran CA, Dominguez-Malagon H, Quevedo-Blanco P, Hum Pathol 1998 29 7 737 742 Epub 1998/07/22 10.1016/S0046-8177(98)90284-2 9670832 (Pubitemid 28322060)