Structure-activity relationship for the development of a self-adjuvanting mucosally active lipopeptide vaccine against Streptococcus pyogenes

Journal of Medicinal Chemistry

Volumn 55, Issue 19, 2012, Pages 8515-8523

  Zaman, Mehfuz ^a   Abdel Aal, Abu Baker M ^a   Fujita, Yoshio ^a   Ziora, Zyta M ^a   Batzloff, Michael R ^b   Good, Michael F ^b   Toth, Istvan ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b GRIFFITH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT; EPITOPE; IMMUNOGLOBULIN A; LIPOPEPTIDE; M PROTEIN; M PROTEIN J14; PEPTIDE VACCINE; TOLL LIKE RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; CONTROLLED STUDY; FEMALE; GROUP A STREPTOCOCCAL INFECTION; HELPER CELL; IMMUNIZATION; IMMUNOGENICITY; MOUSE; MUCOSAL IMMUNITY; NONHUMAN; PEPTIDE SYNTHESIS; STREPTOCOCCUS PYOGENES; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIGENS, BACTERIAL; B-LYMPHOCYTES; BACTERIAL OUTER MEMBRANE PROTEINS; CARRIER PROTEINS; EPITOPES; FEMALE; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; LIPOPEPTIDES; MICE; SPECIES SPECIFICITY; STREPTOCOCCAL INFECTIONS; STREPTOCOCCAL VACCINES; STREPTOCOCCUS PYOGENES; STRUCTURE-ACTIVITY RELATIONSHIP; T-LYMPHOCYTES, HELPER-INDUCER; VACCINES, SUBUNIT;

EID: 84867357747     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301074n     Document Type: Article

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