Iron chelation inhibits the development of pulmonary vascular remodeling

Free Radical Biology and Medicine

Volumn 53, Issue 9, 2012, Pages 1738-1747

  Wong, Chi Ming ^a   Preston, Ioana R ^b   Hill, Nicholas S ^b   Suzuki, Yuichiro J ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

Carbonylation; Free radicals; Iron; Pulmonary hypertension; Reactive oxygen species

Indexed keywords

CARBONYL DERIVATIVE; DEFEROXAMINE MESYLATE; ENDOTHELIN 1; GUANOSINE DIPHOSPHATE; IRON; PLATELET DERIVED GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DISEASE MODEL; HUMAN; HUMAN CELL; HYPOXIA; IRON CHELATION; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEOMICS; PULMONARY ARTERY; PULMONARY HYPERTENSION; PULMONARY VASCULAR REMODELING; RAT; SMOOTH MUSCLE FIBER;

ANIMALS; BLOOD PROTEINS; CASE-CONTROL STUDIES; CELL PROLIFERATION; CELLS, CULTURED; DEFEROXAMINE; FEMALE; HUMANS; HYDRALAZINE; HYPERTENSION, PULMONARY; IRON CHELATING AGENTS; MALE; MIDDLE AGED; MYOCARDIAL CONTRACTION; MYOCYTES, SMOOTH MUSCLE; OXIDATION-REDUCTION; PROTEIN CARBONYLATION; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR ALPHA; VASODILATOR AGENTS;

EID: 84867355830     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.08.576     Document Type: Article

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