Salicylanilide inhibitors of Toxoplasma gondii

Journal of Medicinal Chemistry

Volumn 55, Issue 19, 2012, Pages 8375-8391

  Fomovska, Alina ^a   Wood, Richard D ^b   Mui, Ernest ^a   Dubey, Jitenter P ^c   Ferreira, Leandra R ^c   Hickman, Mark R ^d   Lee, Patricia J ^d   Leed, Susan E ^d   Auschwitz, Jennifer M ^d   Welsh, William J ^b,e   Sommerville, Caroline ^f   Woods, Stuart ^f   Roberts, Craig ^f   McLeod, Rima ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b Snowdon Inc   (United States)

^c AGRICULTURAL RESEARCH SERVICE   (United States)

^d WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^e RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[2,4 BIS( TRIFLUOROMETHYL)PHENYL]CARBAMOYL] 4 CHLOROPHENYL(2HYDRAZINYL 2 OXOETHYL)](METHYL)AMINO]ACETIC ACID; 2 [[[2 [[2,4 BIS( TRIFLUOROMETHYL)PHENYL]CARBAMOYL] 4 CHLOROPHENOXY)CARBONYL](METHYL)AMINO]ACETIC ACID; 4 CHLORO 2 [(2 CHLORO 4 NITROPHENYL)CARBAMOYL]PHENYL BENZOATE; 5 CHLORO 2 HYDROXY N (3,4,5 TRIMETHOXYPHENYL)BENZAMIDE; 5 CHLORO N (2 CHLORO 5 CYANOPHENYL) 2 HYDROXYBENZAMIDE; 5 CHLORO N (3 CYANO 4 FLUOROPHENYL) 2 HYDROXYBENZAMIDE; 5 CHLORO N (3 ETHOXYPHENYL) 2 HYDROXYBENZAMIDE; 5 CHLORO N (3,5 DIMETHYLPHENYL) 2 HYDROXYBENZAMIDE; 5 CHLORO N (4 CHLORO 2 FLUOROPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; ANILIDE; CHLOROQUINE; N (2 CHLORO 4 NITROPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (2 CHLORO 5 NITROPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (2,4 DICHLOROPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (2,4 DIFLUOROPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 BENZYL PHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 BROMOPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 CYANOPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 ETHYLPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 ETHYNYLPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 FLUOROPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 METHYLPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 TERT BUTYLPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3 VINYLPHENYL) 5 CHLORO 2 HYDROXYBENZAMIDE; N (3,5 BIS(TRIFLOUROMETHYL)PHENYL 5 CHLORO 2 HYDROXYBENZAMIDE; N [3 (TRIFLUOROMETHYL)PHENYL] 5 CHLORO 2 HYDROXYBENZAMIDE; NICLOSAMIDE; PYRIMETHAMINE; SULFADIAZINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN CELL; IC 50; MOUSE; NONHUMAN; OOCYST; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ANIMALS; ANTIMALARIALS; ANTIPARASITIC AGENTS; CELLS, CULTURED; DRUG RESISTANCE; FEMALE; FIBROBLASTS; HUMANS; MICE; MICE, TRANSGENIC; PLASMODIUM FALCIPARUM; SALICYLANILIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TOXOPLASMA; TOXOPLASMOSIS;

EID: 84867347218     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3007596     Document Type: Article

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