Immunophenotyping in post-giardiasis functional gastrointestinal disease and chronic fatigue syndrome

BMC Infectious Diseases

Volumn 12, Issue , 2012, Pages

  Hanevik, Kurt ^a,b   Kristoffersen, Einar K ^a,b   Sørnes, Steinar ^a   Mørch, Kristine ^b   Næss, Halvor ^b   Rivenes, Ann C ^b   Bødtker, Jørn E ^b   Hausken, Trygve ^a   Langeland, Nina ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

CD8 T cells; Chronic fatigue syndrome; Functional gastrointestinal disorder; Giardia lamblia; Irritable bowel syndrome; NK cells

Indexed keywords

DIPEPTIDYL PEPTIDASE IV;

ABDOMINAL DISEASE; ADULT; AGED; ARTICLE; CD8+ T LYMPHOCYTE; CHRONIC FATIGUE SYNDROME; CONTROLLED STUDY; DIGESTIVE SYSTEM FUNCTION DISORDER; DISEASE SEVERITY; EPIDEMIC; FEMALE; FLOW CYTOMETRY; GIARDIASIS; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; INFECTION COMPLICATION; MAJOR CLINICAL STUDY; MALE; NATURAL KILLER CELL; PERIPHERAL LYMPHOCYTE; PROTEIN EXPRESSION; QUESTIONNAIRE;

ADULT; AGED; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FATIGUE SYNDROME, CHRONIC; FEMALE; GASTROINTESTINAL DISEASES; GIARDIASIS; HUMANS; IMMUNOPHENOTYPING; MALE; MIDDLE AGED;

EID: 84867314134     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-12-258     Document Type: Article

References (48)

1. Okhuysen PC. Traveler's diarrhea due to intestinal protozoa. Clin Infect Dis 2001, 33:110-114. 10.1086/320894, 11389503.
2. Hanevik K, Dizdar V, Langeland N, Hausken T. Development of functional gastrointestinal disorders after giardia lamblia infection. BMC Gastroenterol 2009, 9:27. 10.1186/1471-230X-9-27, 2676300, 19383162.
3. Wensaas KA, Langeland N, Hanevik K, Morch K, Eide GE, Rortveit G. Irritable bowel syndrome and chronic fatigue 3 years after acute giardiasis: historic cohort study. Gut 2012, 61:214-219. 10.1136/gutjnl-2011-300220, 21911849.
4. Nygard K, Schimmer B, Sobstad O, Walde AK, Tveit I, Langeland N, et al. A large community outbreak of waterborne giardiasis- delayed detection in a non-endemic urban area. BMC Public Health 2006, 6:141. 10.1186/1471-2458-6-141, 1524744, 16725025.
5. Thompson WG, Longstreth GF, Drossman DA, Heaton KW, Irvine EJ, Muller-Lissner SA. Functional bowel disorders and functional abdominal pain. Gut 1999, 45(Suppl 2):II43-II47. 1766683, 10457044.
6. Simren M, Svedlund J, Posserud I, Bjornsson ES, Abrahamsson H. Predictors of subjective fatigue in chronic gastrointestinal disease. Aliment Pharmacol Ther 2008, 28:638-647. 10.1111/j.1365-2036.2008.03770.x, 18564325.
7. Whitehead WE, Palsson O, Jones KR. Systematic review of the comorbidity of irritable bowel syndrome with other disorders: what are the causes and implications?. Gastroenterology 2002, 122:1140-1156. 10.1053/gast.2002.32392, 11910364.
8. Devanur LD, Kerr JR. Chronic fatigue syndrome. J Clin Virol 2006, 37:139-150. 10.1016/j.jcv.2006.08.013, 16978917.
9. Spiller R, Garsed K. Postinfectious irritable bowel syndrome. Gastroenterology 2009, 136:1979-1988. 10.1053/j.gastro.2009.02.074, 19457422.
10. Hickie I, Davenport T, Wakefield D, Vollmer-Conna U, Cameron B, Vernon SD, et al. Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study. BMJ 2006, 333:575. 10.1136/bmj.38933.585764.AE, 1569956, 16950834.
11. Natelson BH, Haghighi MH, Ponzio NM. Evidence for the presence of immune dysfunction in chronic fatigue syndrome. Clin Diagn Lab Immunol 2002, 9:747-752. 120010, 12093668.
12. Brenu EW, van Driel ML, Staines DR, Ashton KJ, Ramos SB, Keane J, et al. Immunological abnormalities as potential biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis. J Transl Med 2011, 9:81. 10.1186/1479-5876-9-81, 3120691, 21619669.
13. Fletcher MA, Zeng XR, Maher K, Levis S, Hurwitz B, Antoni M, et al. Biomarkers in chronic fatigue syndrome: evaluation of natural killer cell function and dipeptidyl peptidase IV/CD26. PLoS One 2010, 5:e10817. 10.1371/journal.pone.0010817, 2876037, 20520837.
14. Holmen N, Isaksson S, Simren M, Sjovall H, Ohman L. CD4+CD25+ regulatory T cells in irritable bowel syndrome patients. Neurogastroenterol Motil 2007, 19:119-125. 10.1111/j.1365-2982.2006.00878.x, 17244166.
15. Ohman L, Isaksson S, Lindmark AC, Posserud I, Stotzer PO, Strid H, et al. T-cell activation in patients with irritable bowel syndrome. Am J Gastroenterol 2009, 104:1205-1212. 10.1038/ajg.2009.116, 19367268.
16. Kindt S, Van OL, Broekaert D, Kasran A, Ceuppens JL, Bossuyt X, et al. Immune dysfunction in patients with functional gastrointestinal disorders. Neurogastroenterol Motil 2009, 21:389-398. 10.1111/j.1365-2982.2008.01220.x, 19126184.
17. Ohman L, Lindmark AC, Isaksson S, Posserud I, Strid H, Sjovall H, et al. B-cell activation in patients with irritable bowel syndrome (IBS). Neurogastroenterol Motil 2009, 21:644-650. e27, 10.1111/j.1365-2982.2009.01272.x, 19222763.
18. Gow JW, Hagan S, Herzyk P, Cannon C, Behan PO, Chaudhuri A. A gene signature for post-infectious chronic fatigue syndrome. BMC Med Genomics 2009, 2:38. 10.1186/1755-8794-2-38, 2716361, 19555476.
19. Masuda A, Munemoto T, Yamanaka T, Takei M, Tei C. Psychosocial characteristics and immunological functions in patients with postinfectious chronic fatigue syndrome and noninfectious chronic fatigue syndrome. J Behav Med 2002, 25:477-485. 10.1023/A:1020423124675, 12442562.
20. Mearin F. Postinfectious functional gastrointestinal disorders. J Clin Gastroenterol 2011, 45:S102-S105. Proceedings from the Pan-European Conference on Irritable Bowel Syndrome December 10, 2010 Vienna, Austria.
21. Thabane M, Kottachchi DT, Marshall JK. Systematic review and meta-analysis: the incidence and prognosis of post-infectious irritable bowel syndrome. Aliment Pharmacol Ther 2007, 26:535-544. 10.1111/j.1365-2036.2007.03399.x, 17661757.
22. Faubert G. Immune response to giardia duodenalis. Clin Microbiol Rev 2000, 13:35-54. 10.1128/CMR.13.1.35-54.2000, 88932, 10627490.
23. Li E, Zhou P, Petrin Z, Singer SM. Mast cell-dependent control of giardia lamblia infections in mice. Infect Immun 2004, 72:6642-6649. 10.1128/IAI.72.11.6642-6649.2004, 523017, 15501797.
24. Langford TD, Housley MP, Boes M, Chen JZ, Kagnoff MF, Gillin FD, et al. Central importance of immunoglobulin a in host defense against giardia spp. Infect Immun 2002, 70:11-18. 10.1128/IAI.70.1.11-18.2002, 127595, 11748158.
25. Palm JE, Weiland ME, Griffiths WJ, Ljungstrom I, Svard SG. Identification of immunoreactive proteins during acute human giardiasis. J Infect Dis 2003, 187:1849-1859. 10.1086/375356, 12792861.
26. Singer SM, Nash TE. T-cell-dependent control of acute giardia lamblia infections in mice. Infect Immun 2000, 68:170-175. 10.1128/IAI.68.1.170-175.2000, 97117, 10603384.
27. Heyworth MF, Carlson JR, Ermak TH. Clearance of giardia muris infection requires helper/inducer T lymphocytes. J Exp Med 1987, 165:1743-1748. 10.1084/jem.165.6.1743, 2188375, 2953846.
28. Scott KG, Yu LC, Buret AG. Role of CD8+ and CD4+ T lymphocytes in jejunal mucosal injury during murine giardiasis. Infect Immun 2004, 72:3536-3542. 10.1128/IAI.72.6.3536-3542.2004, 415705, 15155662.
29. Heyworth MF, Kung JE, Eriksson EC. Clearance of Giardia muris infection in mice deficient in natural killer cells. Infect Immun 1986, 54:903-904. 260258, 3781631.
30. Chalder T, Berelowitz G, Pawlikowska T, Watts L, Wessely S, Wright D, et al. Development of a fatigue scale. J Psychosom Res 1993, 37:147-153. 10.1016/0022-3999(93)90081-P, 8463991.
31. Longstreth GF, Thompson WG, Chey WD, Houghton LA, Mearin F, Spiller RC. Functional bowel disorders. Gastroenterology 2006, 130:1480-1491. 10.1053/j.gastro.2005.11.061, 16678561.
32. Verweij JJ, Schinkel J, Laeijendecker D, Van Rooyen MA, Van LL, Polderman AM. Real-time PCR for the detection of giardia lamblia. Mol Cell Probes 2003, 17:223-225. 10.1016/S0890-8508(03)00057-4, 14580396.
33. Kane SV, Sandborn WJ, Rufo PA, Zholudev A, Boone J, Lyerly D, et al. Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation. Am J Gastroenterol 2003, 98:1309-1314. 10.1111/j.1572-0241.2003.07458.x, 12818275.
34. Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. International chronic fatigue syndrome study group. Ann Intern Med 1994, 121:953-959.
35. Borrego F, Alonso MC, Galiani MD, Carracedo J, Ramirez R, Ostos B, et al. NK phenotypic markers and IL2 response in NK cells from elderly people. Exp Gerontol 1999, 34:253-265. 10.1016/S0531-5565(98)00076-X, 10363791.
36. Giglio T, Imro MA, Filaci G, Scudeletti M, Puppo F, De CL, et al. Immune cell circulating subsets are affected by gonadal function. Life Sci 1994, 54:1305-1312. 10.1016/0024-3205(94)00508-7, 8190002.
37. Linghu EQ, Yang YS. Analysis of peripheral blood lymphocytes subgroup in irritable bowel syndrome. Chin J Dig 2002, 22:423-425.
38. Jin HB, Gu ZY, Zhao HW, Wang QY, Wu W, Li YM. T lymphocyte subgroups and serum levels of trace elements in patients with diarrhea type of irritable bowel syndrome. Zhejiang Da Xue Xue Bao Yi Xue Ban 2008, 37:634-637.
39. Laurence J. T-cell subsets in health, infectious disease, and idiopathic CD4+ T lymphocytopenia. Ann Intern Med 1993, 119:55-62.
40. Liu CC, Huang KJ, Lin YS, Yeh TM, Liu HS, Lei HY. Transient CD4/CD8 ratio inversion and aberrant immune activation during dengue virus infection. J Med Virol 2002, 68:241-252. 10.1002/jmv.10198, 12210415.
41. Ablashi DV. Viral studies of chronic fatigue syndrome. Clin Infect Dis 1994, 18(Suppl 1):S130-S133.
42. Motzer SA, Jarrett M, Heitkemper MM, Tsuji J. Natural killer cell function and psychological distress in women with and without irritable bowel syndrome. Biol Res Nurs 2002, 4:31-42. 10.1177/1099800402004001005, 12363280.
43. Elsenbruch S, Holtmann G, Oezcan D, Lysson A, Janssen O, Goebel MU, et al. Are there alterations of neuroendocrine and cellular immune responses to nutrients in women with irritable bowel syndrome?. Am J Gastroenterol 2004, 99:703-710. 10.1111/j.1572-0241.2004.04138.x, 15089905.
44. Racciatti D, Dalessandro M, Delle DL, Falasca K, Zingariello P, Paganelli R, et al. Study of immune alterations in patients with chronic fatigue syndrome with different etiologies. Int J Immunopathol Pharmacol 2004, 17:57-62.
45. Masuda A, Nakayama T, Yamanaka T, Koga Y, Tei C. The prognosis after multidisciplinary treatment for patients with postinfectious chronic fatigue syndrome and noninfectious chronic fatigue syndrome. J Behav Med 2002, 25:487-497. 10.1023/A:1020475108745, 12442563.
46. Irwin M, Lacher U, Caldwell C. Depression and reduced natural killer cytotoxicity: a longitudinal study of depressed patients and control subjects. Psychol Med 1992, 22:1045-1050. 10.1017/S0033291700038617, 1488477.
47. Gleeson M, Bishop NC. The T cell and NK cell immune response to exercise. Ann Transplant 2005, 10:43-48.
48. Cohen F, Kemeny ME, Zegans LS, Johnson P, Kearney KA, Stites DP. Immune function declines with unemployment and recovers after stressor termination. Psychosom Med 2007, 69:225-234. 10.1097/PSY.0b013e31803139a6, 17401058.