Neurovirulence of H5N1 Infection in Ferrets Is Mediated by Multifocal Replication in Distinct Permissive Neuronal Cell Regions

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Plourde, Jennifer R ^a,b   Pyles, John A ^a   Layton, R Colby ^a,c   Vaughan, Sarah E ^a,b   Tipper, Jennifer L ^a   Harrod, Kevin S ^a,b  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c MRIGlobal   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVIAN INFLUENZA VIRUS; BRAIN; BRAIN CORTEX; BRAIN INFECTION; BRAIN STEM; CELL DIFFERENTIATION; CEREBELLUM; CONTROLLED STUDY; DISEASE SEVERITY; FERRET; FRONTAL CORTEX; INFLUENZA A (H5N1); INFLUENZA VIRUS A; INFLUENZA VIRUS A HK483; INFLUENZA VIRUS A VN1203; LETHALITY; LUNG DISEASE; MALE; MIXED INFECTION; NEUROLOGIC DISEASE; NEUROTROPISM; NONHUMAN; NOSE MUCOSA; OLFACTORY BULB; OLFACTORY NERVE; PARESIS; PURKINJE CELL; SEIZURE; TORTICOLLIS; TURBINATE; VIRUS IDENTIFICATION; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; CENTRAL NERVOUS SYSTEM; FERRETS; IMMUNOHISTOCHEMISTRY; INFLUENZA A VIRUS, H5N1 SUBTYPE; MALE; ORTHOMYXOVIRIDAE INFECTIONS; REAL-TIME POLYMERASE CHAIN REACTION; VIRULENCE; VIRUS REPLICATION;

EID: 84867305656     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046605     Document Type: Article

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