Pseudohalide anions reveal a novel extracellular site for potentiators to increase CFTR function

British Journal of Pharmacology

Volumn 167, Issue 5, 2012, Pages 1062-1075

  Li, Man Song ^a   Cowley, Elizabeth A ^a   Linsdell, Paul ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

anion binding site; chloride channel; cystic fibrosis; cystic fibrosis transmembrane conductance regulator; patch clamp; potentiator

Indexed keywords

ANION; COBALT; IRIDIUM; IRON; MUTANT PROTEIN; PSEUDOHALIDE ANION; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL INTERACTION; CELLULAR SECRETION; CHEMICAL INTERACTION; CONTROLLED STUDY; CYTOPLASM; ELECTRIC CURRENT; EPITHELIUM CELL; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; ION CONDUCTANCE; MICROSCOPY; MOLECULAR MECHANICS; MUTAGENESIS; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; RESPIRATORY EPITHELIUM;

ANIMALS; CELL LINE; COBALT; CRICETINAE; CYANIDES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HUMANS; IRIDIUM; MUTATION; PLATINUM COMPOUNDS;

EID: 84867292821     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02041.x     Document Type: Article

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