Increased Oxidative Damage in Carriers of the Germline TP53 p.R337H Mutation

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Macedo, Gabriel S ^a,b   Lisbôa da Motta, Leonardo ^a,c,d   Giacomazzi, Juliana ^a,b   Netto, Cristina B O ^b   Manfredini, Vanusa ^e   S Vanzin, Camila ^a,b   Vargas, Carmen Regla ^a,b   Hainaut, Pierre ^f   Klamt, Fábio ^a,c,d   Ashton Prolla, Patricia ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^c Instituto Nacional de Ciência e Tecnologia Translacional em Medicina INCT TM   (Brazil)

^d Rede Gaúcha de Estresse Oxidativo e Sinalização Celular FAPERGS   (Brazil)

^e UNIVERSIDADE FEDERAL DO PAMPA   (Brazil)

^f INTERNATIONAL PREVENTION RESEARCH INSTITUTE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; CARBONYL DERIVATIVE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PROTEIN P53;

ADOLESCENT; ADULT; ARTICLE; BIOENERGY; BLOOD SAMPLING; CARCINOGENESIS; CELL STRESS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BLOOD LEVEL; FEMALE; GENE; GENE MUTATION; HETEROZYGOTE; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MALE; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRESCHOOL CHILD; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; PROTEIN FUNCTION; REGULATORY MECHANISM; SCHOOL CHILD; TP53 GENE; VITAMIN BLOOD LEVEL;

ADOLESCENT; ADULT; ANTIOXIDANTS; CHILD; CHILD, PRESCHOOL; CODON; FEMALE; GERM-LINE MUTATION; HETEROZYGOTE; HUMANS; INFANT; MALE; MALONDIALDEHYDE; MIDDLE AGED; OXIDATIVE STRESS; TUMOR SUPPRESSOR PROTEIN P53; YOUNG ADULT;

EID: 84867283938     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047010     Document Type: Article

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