Increased cellular and circulating biomarkers of oxidative stress in nascent metabolic syndrome

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 10, 2012, Pages

  Jialal, Ishwarlal ^a,b   Devaraj, Sridevi ^c   Adams Huet, Beverley ^d   Chen, Xinpu ^c   Kaur, Harmeet ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; BIOLOGICAL MARKER; CELL MARKER; NUCLEAR FACTOR ERYTHROID 2 RELATED FACTOR; OXIDIZED LOW DENSITY LIPOPROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE P22 PHOX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE P47 PHOX; SUPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIET RESTRICTION; FEMALE; HUMAN; MALE; METABOLIC SYNDROME X; MONOCYTE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION;

ADULT; BIOLOGICAL MARKERS; BODY MASS INDEX; CARDIOVASCULAR DISEASES; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; LIPOPROTEINS, LDL; MALE; METABOLIC SYNDROME X; MIDDLE AGED; MONOCYTES; NADPH OXIDASE; NF-E2 TRANSCRIPTION FACTOR; OXIDATIVE STRESS; PREVALENCE; RISK FACTORS; SUPEROXIDES; TYROSINE;

EID: 84867271268     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-2498     Document Type: Article

References (40)

1. Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith Jr SC; International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity 2009 Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity. Circulation 120:1640-1645
2. Eckel RH, Grundy SM, Zimmet PZ 2005 The metabolic syndrome. Lancet 365:1415-1428 (Pubitemid 40523737)
3. Bremer AA, Devaraj S, Afify A, Jialal I 2011 Adipose tissue dysregulation in patients with metabolic syndrome. J Clin Endocrinol Metab 96:E1782-E1788
4. Jialal I, Huet BA, Kaur H, Chien A, Devaraj S 2012 Increased toll-like receptor activity in patients with metabolic syndrome. Diabetes Care 35:900-904
5. Whaley-Connell A, McCullough PA, Sowers JR 2011 The role of oxidative stress in the metabolic syndrome. Rev Cardiovasc Med 12:21-29
6. Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I 2004 Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 114:1752-1761 (Pubitemid 40385531)
7. Jialal I, Devaraj S, Singh U, Huet BA 2010 Decreased number and impaired functionality of endothelial progenitor in subjects with metabolic syndrome: implications for increased cardiovascular risk. Atherosclerosis 211:297-302
8. Devaraj S, Chan E, Jialal I 2006 Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome. J Clin Endocrinol Metab 91:4489-4496 (Pubitemid 44833428)
9. Dasu MR, Devaraj S, Zhao L, Hwang DH, Jialal I 2008 High glucose induces toll-like receptor expression in human monocytes: mechanism of activation. Diabetes 57:3090-3098
10. Dandona P, Aljada A, Chaudhuri A, Mohanty P, Garg R 2005 Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 111:1448-1454 (Pubitemid 40396812)
11. Dikalov S 2011 Cross talk between mitochondria and NADPH oxidases. Free Radic Biol Med 51:1289-1301
12. Fortuño A, San José G, Moreno MU, Beloqui O, Díez J, Zalba G 2006 Phagocytic NADPH oxidase overactivity underlines oxidative stress in metabolic syndrome. Diabetes 55:209-215 (Pubitemid 43343317)
13. Heiss EH, Schachner D, Werner ER, Dirsch VM 2009 Active NF-E2- related factor (Nrf2) contributes to keep endothelial NO synthase (eNOS) in the coupled state role of reactive oxygen species (ROS), eNOS, and heme oxygenase (HO-1) levels. J Biol Chem 284:31579-31586
14. Kang KW, Lee SJ, Kim SG 2005 Molecular mechanism of nrf2 activation by oxidative stress. Antioxid Redox Signal 7:1664-1673 (Pubitemid 41768000)
15. Ceriello A, Motz E 2004 Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited. Arterioscler Thromb Vasc Biol 24:816-823 (Pubitemid 38620857)
16. Giacco F, Brownlee M 2010 Oxidative stress and diabetic complications. Circ Res 107:1058-1070
17. Devaraj S, Jialal I 2000 Low-density lipoprotein postsecretory modification monocyte function, and circulating adhesion molecules in type 2 diabetic patients with and without macrovascular complications: the effect of α-tocopherol supplementation. Circulation 102:191-196 (Pubitemid 30451776)
18. Bokoch GM, Knaus UG 2003 NADPH oxidases: not just for leukocytes anymore! Trends Biochem Sci 28:502-508 (Pubitemid 38340415)
19. Esposito K, Ciotola M, Schisano B, Misso L, Giannetti G, Ceriello A, Giugliano D 2006 Oxidative stress in the metabolic syndrome. J Endocrinol Invest 29:791-795 (Pubitemid 44869423)
20. Delbosc S, Paizanis E, Magous R, Araiz C, Dimo T, Cristol JP, Cros G, Azay J 2005 Involvement of oxidative stress and NADPH oxidase activation in the development of cardiovascular complications in a model of insulin resistance, the fructose-fed rat. Atherosclerosis 179:43-49 (Pubitemid 40249784)
21. Shishehbor MH, Aviles RJ, Brennan ML, Fu X, Goormastic M, Pearce GL, Gokce N, Keaney Jr JF Penn MS, Sprecher DL, Vita JA, Hazen SL 2003 Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy. JAMA 289:1675-1680 (Pubitemid 37430273)
22. Zalba G, Beloqui O, San José G, Moreno MU, Fortuño A, Díez J 2005 NADPH oxidase-dependent superoxide production is associated with carotid intima-media thickness in subjects of clinical atherosclerotic disease. Arterioscler Thromb Vasc Biol 25:1452-1457 (Pubitemid 40923367)
23. Venugopal SK, Devaraj S, Yang T, Jialal I 2002 α-Tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-α. Diabetes 51:3049-3054
24. phox and inducible hemeoxygenase-1 gene expressions are increased in type II diabetic patients: relationship with oxidative stress. J Clin Endocrinol Metab 88:1753-1759
25. Dandona P, Thusu K, Cook S, Snyder B, Makowski J, Armstrong D, Nicotera T 1996 Oxidative damage to DNA in diabetes mellitus. Lancet 347:444-445 (Pubitemid 26054071)
26. Holvoet P, Lee DH, Steffes M, Gross M, Jacobs DR Jr 2008 Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome. JAMA 299:2287-2293 (Pubitemid 351724395)
27. Holvoet P, De Keyzer D, Jacobs Jr DR 2008 Oxidized LDL and the metabolic syndrome. Future Lipidol 3:637-649
28. Meisinger C, Baumert J, Khuseyinova N, Loewel H, Koenig W 2005 Plasma oxidized low-density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle-aged men from the general population. Circulation 112:651-657 (Pubitemid 41099043)
29. Huang PL 2005 Unraveling the links between diabetes, obesity, and cardiovascular disease. Circ Res 96:1129-1131 (Pubitemid 40827686)
30. Sjogren P, Basu S, Rosell M, Silveira A, de Faire U, Vessby B, Hamsten A, Hellenius ML, Fisher RM 2005 Measures of oxidized lowdensity lipoprotein and oxidative stress are not related and not elevated in otherwise healthy men with the metabolic syndrome. Arterioscler Thromb Vasc Biol 25:2580-2586 (Pubitemid 43732282)
31. Ceriello A, Mercuri F, Quagliaro L, Assaloni R, Motz E, Tonutti L, Taboga C 2001 Detection of nitrotyrosine in the diabetic plasma: evidence of oxidative stress. Diabetologia 44:834-838 (Pubitemid 32642455)
32. Yamaguchi Y, Yoshikawa N, Kagota S, Nakamura K, Haginaka J, Kunitomo M 2006 Elevated circulating levels of markers of oxida-tive- nitrative stress and inflammation in a genetic rat model of metabolic syndrome. Nitric Oxide 15:380-386 (Pubitemid 44647897)
33. Cheng X, Sow RC, Mann GE 2011 Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-e2-related factor 2-kelch-like ech-associated protein 1 defense pathway. Antioxid Redox Signal 14:469-487
34. Xue Q, Qian Q, Adaikalakoteswari A, Rabbani N, Babaei-Jadidi R, Thornalley PJ 2008 Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes 57:2809-2817
35. Pi J, Zhang Q, Fu J, Woods CG, Hou Y, Corkey BE, Collins S, Andersen ME 2010 ROS signaling, oxidative stress and Nrf2 in pancreatic β-cell function. Toxicol Appl Pharmacol 244:77-83
36. Tan Y, Ichikawa T, Li J, Si Q, Yang H, Chen X, Goldblatt CS, Meyer CJ, Li X, Cai L, Cui T 2011 Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo. Diabetes 60:625-633
37. Ghanim H, Sia CL, Korzeniewski K, Lohano T, Abuaysheh S, Marumganti A, Chaudhuri A, Dandona P 2011 A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal. J Clin Endocrinol Metab 96:1409-1414
38. Singh U, Devaraj S, Jialal I, Siegel D 2008 Comparison effect of atorvastatin (10 versus 80 mg) on biomarkers of inflammation and oxidative stress in subjects with metabolic syndrome. Am J Cardiol 102:321-325
39. Devaraj S, Valleggi S, Siegel D, Jialal I 2010 Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome. Curr Atheroscler Res 12:110-118
40. Weseler AR, Bast A 2010 Oxidative stress and vascular function: implications for pharmacologic treatments. Curr Hypertens Rep 12:154-161