MR liver imaging with Gd-EOB-DTPA: A delay time of 10 minutes is sufficient for lesion characterisation

European Radiology

Volumn 22, Issue 10, 2012, Pages 2153-2160

  Van Kessel, C S ^a   Veldhuis, W B ^a   Van Den Bosch, M A A J ^a   Van Leeuwen, M S ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Dynamic contrast enhanced MRI; Examination time; Gd EOB DTPA; Hepatobiliary imaging; Lesion characterisation

Indexed keywords

GADOXETIC ACID;

ADULT; AGED; ARTICLE; BILE DUCT; CLINICAL ASSESSMENT; COLORECTAL CARCINOMA; CONTRAST ENHANCEMENT; CONTRAST NOISE RATIO; FEMALE; HEPATOBILIARY DISEASE; HEPATOBILIARY SYSTEM; HUMAN; LIVER CELL CARCINOMA; LIVER DISEASE; LIVER FUNCTION; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL PARAMETERS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SIGNAL NOISE RATIO;

ADULT; AGED; CONTRAST MEDIA; FEMALE; GADOLINIUM DTPA; HUMANS; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 84867266275     PISSN: 09387994     EISSN: 14321084     Source Type: Journal    
DOI: 10.1007/s00330-012-2486-2     Document Type: Article

References (20)

1. Schima W, Saini S, Petersein J et al (1999) MR imaging of the liver with Gd-BOPTA: Quantitative analysis of T1-weighted images at two different doses. J Magn Reson Imaging 10:80-83
2. Vogl TJ, Pegios W, McMahon C et al (1992) Gadobenate dimeglumine-A new contrast agent for MR imaging: Preliminary evaluation in healthy volunteers. AJR Am J Roentgenol 158:887-892
3. Reimer P, Rummeny EJ, Shamsi K et al (1996) Phase II clinical evaluation of Gd-EOB-DTPA: Dose, safety aspects, and pulse sequence. Radiology 199:177-183
4. Reimer P, Vosshenrich R (2010) Detection and characterization of liver lesions using gadoxetic acid as a tissue-specific contrast agent. Biologics 4:199-212
5. Hammerstingl R, Huppertz A, Breuer J et al (2008) Diagnostic efficacy of gadoxetic acid (Primovist)-enhanced MRI and spiral CT for a therapeutic strategy: Comparison with intraoperative and histopathologic findings in focal liver lesions. Eur Radiol 18:457-467
6. Huppertz A, Balzer T, Blakeborough A et al (2004) Improved detection of focal liver lesions at MR imaging: Multicenter comparison of gadoxetic acid-enhanced MR images with intraoperative findings. Radiology 230:266-275
7. Raman SS, Leary C, Bluemke DA et al (2010) Improved characterization of focal liver lesions with liver-specific gadoxetic acid disodium-enhanced magnetic resonance imaging: A multicenter phase 3 clinical trial. J Comput Assist Tomogr 34:163-172
8. Tanimoto A, Lee JM, Murakami T, Huppertz A, Kudo M, Grazioli L (2009) Consensus report of the 2nd international forum for liver MRI. Eur Radiol 19(Suppl 5):S975-S989
9. Lowenthal D, Zeile M, Lim WY et al (2010) Detection and characterisation of focal liver lesions in colorectal carcinoma patients: Comparison of diffusion-weighted and Gd-EOB-DTPA enhanced MR imaging. Eur Radiol 21:832-840
10. Zech CJ, Grazioli L, Breuer J, Reiser MF, Schoenberg SO (2008) Diagnostic performance and description of morphological features of focal nodular hyperplasia in Gd-EOB-DTPA-enhanced liver magnetic resonance imaging: Results of a multicenter trial. Invest Radiol 43:504-511
11. Takao H, Akai H, Tajima T et al (2009) MR imaging of the biliary tract with Gd-EOB-DTPA: Effect of liver function on signal intensity. Eur J Radiol 77:325-329
12. Motosugi U, Ichikawa T, Tominaga L et al (2009) Delay before the hepatocyte phase of Gd-EOB-DTPA-enhanced MR imaging: Is it possible to shorten the examination time? Eur Radiol 19:2623-2629
13. Tschirch FT, Struwe A, Petrowsky H, Kakales I, Marincek B, Weishaupt D (2008) Contrast-enhanced MR cholangiography with Gd-EOB-DTPA in patients with liver cirrhosis: Visualization of the biliary ducts in comparison with patients with normal liver parenchyma. Eur Radiol 18:1577-1586
14. Kim KA, Kim MJ, Park MS et al (2010) Optimal T2-weighted MR cholangiopancreatographic images can be obtained after administration of gadoxetic acid. Radiology 256:475-484
15. Ringe KI, Gupta RT, Brady CM et al (2010) Respiratory-Triggered three-dimensional T2-weighted MR cholangiography after injection of gadoxetate disodium: Is it still reliable? Radiology 255:451-458
16. Kim YK, Kwak HS, Kim CS, Han YM (2009) Detection and characterization of focal hepatic tumors: A comparison of T2-weighted MR images before and after the administration of gadoxetic acid. J Magn Reson Imaging 30:437-443
17. Choi SA, Lee SS, Jung IH, Kim HA, Byun JH, Lee MG (2012) The effect of gadoxetic acid enhancement on lesion detection and characterisation using T2 weighted imaging and diffusion weighted imaging of the liver. Br J Radiol 85:29-36
18. Chiu FY, Jao JC, Chen CY et al (2005) Effect of intravenous gadolinium-DTPA on diffusion-weighted magnetic resonance images for evaluation of focal hepatic lesions. J Comput Assist Tomogr 29:176-180
19. Choi JS, Kim MJ, Choi JY, Park MS, Lim JS, Kim KW (2010) Diffusion-weighted MR imaging of liver on 3.0-Tesla system: Effect of intravenous administration of gadoxetic acid disodium. Eur Radiol 20:1052-1060
20. Motosugi U, Ichikawa T, Sou H et al (2009) Dilution method of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI). J Magn Reson Imaging 30:849-854