Determinants of lymph node count in endometrial cancer surgical staging

International Journal of Gynecological Cancer

Volumn 22, Issue 8, 2012, Pages 1361-1366

  Cormier, Beatrice ^a   Sauthier, Philippe ^a   Lussier, Christian ^b   Zang, Geng ^c   Mayrand, Marie Helene ^c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b HÔPITAL DU SACRÉ COEUR DE MONTRÉAL   (Canada)

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Endometrial cancer; Lymph node count; Lymphadenectomy

Indexed keywords

ACCURACY; ADULT; ARTICLE; BODY MASS; CANCER STAGING; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; ENDOMETRIUM CANCER; FEMALE; HUMAN; LYMPH NODE COUNT; LYMPH NODE DISSECTION; LYMPHATIC SYSTEM EXAMINATION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

ADENOCARCINOMA; AGED; CARCINOSARCOMA; ENDOMETRIAL NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 84867248767     PISSN: 1048891X     EISSN: 15251438     Source Type: Journal    
DOI: 10.1097/IGC.0b013e318269e29d     Document Type: Article

References (25)

1. Morrow CP, Bundy BN, Kurman RJ, et al. Relationship between surgical-pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: a Gynecologic Oncology Group study. Gynecol Oncol. 1991;40:55-65.
2. Herr HW, Bochner BH, Dalbagni G, et al. Impact of the number of lymph nodes retrieved on outcome in patients with muscle invasive bladder cancer. J Urol. 2002;167: 1295-1298.
3. Le Voyer TE, Sigurdson ER, Hanlon AL, et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol. 2003;21:2912-2919.
4. Mersin H, Yildirim E, Bulut H, et al. The prognostic significance of total lymph node number in patients with axillary lymph node-negative breast cancer. Eur J Surg Oncol. 2003;29:132-138.
5. Tepper JE, O'Connell MJ, Niedzwiecki D, et al. Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol. 2001;19:157-163.
6. Weir L, Speers C, D'Yachkova Y, et al. Prognostic significance of the number of axillary lymph nodes removed in patients with node-negative breast cancer. J Clin Oncol. 2002;20:1793-1799.
7. Benson AB, 3rd, Schrag D, Somerfield MR, et al. American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer. J Clin Oncol. 2004;22:3408-3419.
8. Nelson H, Petrelli N, Carlin A, et al. Guidelines 2000 for colon and rectal cancer surgery. J Natl Cancer Inst. 2001;93:583-596.
9. Abu-Rustum NR, Iasonos A, Zhou Q, et al. Is there a therapeutic impact to regional lymphadenectomy in the surgical treatment of endometrial carcinoma? Am J Obstet Gynecol. 2008;198:457.e1-457.e5 discussion 457.e5-457.e6.
10. Lutman CV, Havrilesky LJ, Cragun JM, et al. Pelvic lymph node count is an important prognostic variable for FIGO stage I and II endometrial carcinoma with high-risk histology. Gynecol Oncol. 2006;102:92-97.
11. Chan JK, Urban R, Cheung MK, et al. Lymphadenectomy in endometrioid uterine cancer staging: how many lymph nodes are enough? A study of 11,443 patients. Cancer. 2007; 109:2454-2460.
12. Cragun JM, Havrilesky LJ, Calingaert B, et al. Retrospective analysis of selective lymphadenectomy in apparent early-stage endometrial cancer. J Clin Oncol. 2005;23:3668-3675.
13. Smith DC, Macdonald OK, Lee CM, et al. Survival impact of lymph node dissection in endometrial adenocarcinoma: a surveillance, epidemiology, and end results analysis. Int J Gynecol Cancer. 2008;18:255-261.
14. Chan JK, Cheung MK, Huh WK, et al. Therapeutic role of lymph node resection in endometrioid corpus cancer: a study of 12,333 patients. Cancer. 2006;107:1823-1830.
15. Kitchener H, Swart AM, Qian Q, et al. Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study. Lancet. 2009;373:125-136.
16. Benedetti Panici P, Basile S, Maneschi F, et al. Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial. J Natl Cancer Inst. 2008;100:1707-1716.
17. Havrilesky LJ, Cragun JM, Calingaert B, et al. Resection of lymph node metastases influences survival in stage IIIC endometrial cancer. Gynecol Oncol. 2005;99:689-695.
18. Kehoe SM, Miller DS. The role of lymphadenectomy in endometrial cancer. Clin Obstet Gynecol. 2011;54:235-244.
19. Euscher ED, Bassett R, Malpica A. Lymph node counts in endometrial cancer: expectations versus reality. Am J Surg Pathol. 2011;35:913-918.
20. Lanowska M, Vasiljeva J, Chiantera V, et al. Implication of the examining pathologist to meet the oncologic standard of lymph node count after laparoscopic lymphadenectomy. Oncology. 2010;79:161-167.
21. Forde GK, Carlson JW, Downey GO, et al. A quality process study of lymph node evaluation in endometrial cancer. Int J Gynecol Pathol. 2011;30:335-339.
22. Mhawech-Fauceglia P, Herrmann FR, Wagner H, et al. Submission of the entire lymph node dissection for histologic examination in gynecologic-oncologic specimens. Clinical and pathologic relevance. Gynecol Oncol. 2009;115:354-356.
23. Santoso JT, Azadi A,Wan J, et al. Lymph node counts in uterine cancer: a randomized double blind trial. Gynecol Oncol. 2009;113:159-162.
24. Panici PB, Scambia G, Baiocchi G, et al. Anatomical study of para-aortic and pelvic lymph nodes in gynecologic malignancies. Obstet Gynecol. 1992;79: 498-502.
25. Plentl AA, Friedman EA. Lymphatic system of the female genitalia. The morphologic basis of oncologic diagnosis and therapy. Major Probl Obstet Gynecol. 1971;2: 1-223.