-
1
-
-
34248223285
-
Biology of Incretins: GLP-1 and GIP
-
DOI 10.1053/j.gastro.2007.03.054, PII S001650850700580X
-
Baggio LL, Drucker DJ 2007 Biology of incretins: GLP-1 and GIP. Gastroenterology 132:2131-2157 (Pubitemid 46711096)
-
(2007)
Gastroenterology
, vol.132
, Issue.6
, pp. 2131-2157
-
-
Baggio, L.L.1
Drucker, D.J.2
-
2
-
-
58149090676
-
The role of incretins in glucose homeostasis and diabetes treatment
-
Kim W, Egan JM 2008 The role of incretins in glucose homeostasis and diabetes treatment. Pharmacol Rev 60:470-512
-
(2008)
Pharmacol Rev
, vol.60
, pp. 470-512
-
-
Kim, W.1
Egan, J.M.2
-
3
-
-
67649518005
-
Unraveling the science of incretin biology
-
Nauck MA 2009 Unraveling the science of incretin biology. Eur J Intern Med 20(Suppl 2):S303-S308
-
(2009)
Eur J Intern Med
, vol.20
, Issue.SUPPL. 2
-
-
Nauck, M.A.1
-
4
-
-
24944577486
-
Alpha cell function in health and disease: Influence of glucagon-like peptide-1
-
DOI 10.1007/s00125-005-1878-0
-
Dunning BE, Foley JE, Ahrén B 2005 α-Cell function in health and disease: influence of glucagon-like peptide-1. Diabetologia 48: 1700-1713 (Pubitemid 41317822)
-
(2005)
Diabetologia
, vol.48
, Issue.9
, pp. 1700-1713
-
-
Dunning, B.E.1
Foley, J.E.2
Ahren, B.3
-
5
-
-
82255185915
-
Glucose-dependent inulinotropic polypeptide: A bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans
-
Christensen M, Vedtofte L, Holst JJ, Vilsbøll T, Knop FK 2011 Glucose-dependent inulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans. Diabetes 60:3103-3109
-
(2011)
Diabetes
, vol.60
, pp. 3103-3109
-
-
Christensen, M.1
Vedtofte, L.2
Holst, J.J.3
Vilsbøll, T.4
Knop, F.K.5
-
6
-
-
23844463766
-
Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed β-cell function in patients with type 2 diabetes
-
DOI 10.1210/jc.2004-2460
-
Mari A, Sallas WM, He YL, Watson C, Ligueros-Saylan M, Dunning BE, Deacon CF, Holst JJ, Foley JE 2005 Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed β-cell function in patients with type 2 diabetes. J Clin Endocrinol Metab 90:4888-4894 (Pubitemid 41159387)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.8
, pp. 4888-4894
-
-
Mari, A.1
Sallas, W.M.2
He, Y.L.3
Watson, C.4
Ligueros-Saylan, M.5
Dunning, B.E.6
Deacon, C.F.7
Holst, J.J.8
Foley, J.E.9
-
7
-
-
79960831855
-
Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans
-
Ahrén B, Schweizer A, Dejager S, Villhauer EB, Dunning BE, Foley JE 2011 Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans. Diabetes Obes Metab 13:775-783
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 775-783
-
-
Ahrén, B.1
Schweizer, A.2
Dejager, S.3
Villhauer, E.B.4
Dunning, B.E.5
Foley, J.E.6
-
8
-
-
34548118796
-
1c over 1 year in drug-naive patients with Type 2 diabetes
-
DOI 10.1111/j.1464-5491.2007.02191.x
-
Schweizer A, Couturier A, Foley JE, Dejager S 2007 Comparison between vildagliptin and metformin to sustain reductions in HbA1c over one year in drug-naive patients with type 2 diabetes. Diabet Med 24:955-961 (Pubitemid 47301637)
-
(2007)
Diabetic Medicine
, vol.24
, Issue.9
, pp. 955-961
-
-
Schweizer, A.1
Couturier, A.2
Foley, J.E.3
Dejager, S.4
-
9
-
-
44949170696
-
Efficacy and tolerability of vildagliptin in drug-naive patients with type 2 diabetes and mild hyperglycaemia
-
DOI 10.1111/j.1463-1326.2008.00850.x
-
Scherbaum WA, Schweizer A, Mari A, Nilsson PM, Lalanne G, Jauffret S, Foley JE 2008 Efficacy and tolerability of vildagliptin in drug-naive patients with type 2 diabetes and mild hyperglycemia. Diabetes Obes Metab 10:675-682 (Pubitemid 352044298)
-
(2008)
Diabetes, Obesity and Metabolism
, vol.10
, Issue.8
, pp. 675-682
-
-
Scherbaum, W.A.1
Schweizer, A.2
Mari, A.3
Nilsson, P.M.4
Lalanne, G.5
Jauffret, S.6
Foley, J.7
-
10
-
-
34147093268
-
Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin
-
DOI 10.2337/dc06-1732
-
Bosi E, Camisasca RP, Collober C, Rochotte E, Garber AJ 2007 Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin. Diabetes Care 30:890-895 (Pubitemid 46556583)
-
(2007)
Diabetes Care
, vol.30
, Issue.4
, pp. 890-895
-
-
Bosi, E.1
Camisasca, R.P.2
Collober, C.3
Rochotte, E.4
Garber, A.J.5
-
11
-
-
58149330590
-
Fifty-two-week efficacy and safety of vildagliptin vs. glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy
-
Ferrannini E, Fonseca V, Zinman B, Matthews D, Ahrén B, Byiers S, Shao Q, Dejager S 2009 Fifty-two-week efficacy and safety of vildagliptin vs. glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy. Diabetes Obes Metab 11:157-166
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 157-166
-
-
Ferrannini, E.1
Fonseca, V.2
Zinman, B.3
Matthews, D.4
Ahrén, B.5
Byiers, S.6
Shao, Q.7
Dejager, S.8
-
12
-
-
33846828660
-
Vildagliptin in combination with pioglitazone improves glycaemic control in patients with type 2 diabetes failing thiazolidinedione monotherapy: A randomized, placebo-controlled study
-
DOI 10.1111/j.1463-1326.2006.00684.x, Future Treatments: A Focus on Dipeptidyl Peptidase-IV Inhibitors
-
Garber AJ, Schweizer A, Baron MA, Rochotte E, Dejager S 2007 Vildagliptin in combination with pioglitazone improves glycaemic control in patients with type 2 diabetes failing thiazolidinedione monotherapy: a randomized, placebo controlled study. Diabetes Obes Metab 9:166-174 (Pubitemid 46206560)
-
(2007)
Diabetes, Obesity and Metabolism
, vol.9
, Issue.2
, pp. 166-174
-
-
Garber, A.J.1
Schweizer, A.2
Baron, M.A.3
Rochotte, E.4
Dejager, S.5
-
13
-
-
33846827085
-
Efficacy and tolerability of initial combination therapy with vildagliptin and pioglitazone compared with component monotherapy in patients with type 2 diabetes
-
DOI 10.1111/j.1463-1326.2006.00698.x, Future Treatments: A Focus on Dipeptidyl Peptidase-IV Inhibitors
-
Rosenstock J, Kim SW, Baron MA, Camisasca RP, Cressier F, Couturier A, Dejager S 2007 Efficacy and tolerability of initial combination therapy with vildagliptin and pioglitazone compared to component monotherapy in patients with type 2 diabetes. Diabetes Obes Metab 9:175-185 (Pubitemid 46206561)
-
(2007)
Diabetes, Obesity and Metabolism
, vol.9
, Issue.2
, pp. 175-185
-
-
Rosenstock, J.1
Baron, M.A.2
Camisasca, R.-P.3
Cressier, F.4
Couturier, A.5
Dejager, S.6
-
14
-
-
54249106294
-
Effects of vildagliptin on glucose control in patients with type 2 diabetes inadequately controlled with a sulphonylurea
-
Garber AJ, Foley JE, Banerji MA, Ebeling P, Gudbjörnsdottir S, Camisasca RP, Couturier A, Baron MA 2008 Effects of vildagliptin on glucose control in patients with type 2 diabetes inadequately controlled with a sulphonylurea. Diabetes Obes Metab 10:1047-1056
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 1047-1056
-
-
Garber, A.J.1
Foley, J.E.2
Banerji, M.A.3
Ebeling, P.4
Gudbjörnsdottir, S.5
Camisasca, R.P.6
Couturier, A.7
Baron, M.A.8
-
15
-
-
34247874561
-
Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes
-
DOI 10.1007/s00125-007-0633-0
-
Fonseca V, Schweizer A, Albrecht D, Baron MA, Chang I, Dejager S 2007 Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes. Diabetologia 50:1148-1155 (Pubitemid 46701545)
-
(2007)
Diabetologia
, vol.50
, Issue.6
, pp. 1148-1155
-
-
Fonseca, V.1
Schweizer, A.2
Albrecht, D.3
Baron, M.A.4
Chang, I.5
Dejager, S.6
-
16
-
-
78851471216
-
Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin
-
Ahrén B, Foley JE, Bosi E 2011 Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin. Diabetes Obes Metab 13:193-203
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 193-203
-
-
Ahrén, B.1
Foley, J.E.2
Bosi, E.3
-
17
-
-
77958540127
-
Vildagliptin: A review of its use in type 2 diabetes mellitus
-
Keating GM 2010 Vildagliptin: a review of its use in type 2 diabetes mellitus. Drugs 70:2089-2112
-
(2010)
Drugs
, vol.70
, pp. 2089-2112
-
-
Keating, G.M.1
-
18
-
-
65249095686
-
Vildagliptin enhances islet responsiveness to both hyper- And hypoglycemia in patients with type 2 diabetes
-
Ahrén B, Schweizer A, Dejager S, Dunning BE, Nilsson PM, Persson M, Foley JE 2009 Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes. J Clin Endocrinol Metab 94:1236-1243
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1236-1243
-
-
Ahrén, B.1
Schweizer, A.2
Dejager, S.3
Dunning, B.E.4
Nilsson, P.M.5
Persson, M.6
Foley, J.E.7
-
20
-
-
84857401843
-
Minireview: Glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes
-
Cryer PE 2012 Minireview: glucagon in the pathogenesis of hypoglycemia and hyperglycemia in diabetes. Endocrinology 153:1039-1048
-
(2012)
Endocrinology
, vol.153
, pp. 1039-1048
-
-
Cryer, P.E.1
-
21
-
-
0016846068
-
Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon
-
Gerich JE, Lorenzi M, Bier DM, Schneider V, Tsalikian E, Karam JH, Forsham PH 1975 Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon. N Engl J Med 292:985-989
-
(1975)
N Engl J Med
, vol.292
, pp. 985-989
-
-
Gerich, J.E.1
Lorenzi, M.2
Bier, D.M.3
Schneider, V.4
Tsalikian, E.5
Karam, J.H.6
Forsham, P.H.7
-
22
-
-
54049099230
-
Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes
-
Foley JE, Ligueros-Saylan M, He YL, Holst JJ, Deacon CF, Dunning BE, Leone-Jones A, Yu T, Kelley DE 2008 Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes. Horm Metab Res 40:727-730
-
(2008)
Horm Metab Res
, vol.40
, pp. 727-730
-
-
Foley, J.E.1
Ligueros-Saylan, M.2
He, Y.L.3
Holst, J.J.4
Deacon, C.F.5
Dunning, B.E.6
Leone-Jones, A.7
Yu, T.8
Kelley, D.E.9
-
23
-
-
79961175481
-
The future of incretin-based therapy-novel avenues - novel targets
-
Ahrén B 2011 The future of incretin-based therapy-novel avenues - novel targets. Diabetes Obes Metab 13(Suppl 1):158-166
-
(2011)
Diabetes Obes Metab
, vol.13
, Issue.SUPPL. 1
, pp. 158-166
-
-
Ahrén, B.1
-
24
-
-
79959392262
-
Liraglutide as additional treatment for type 1 diabetes
-
Varanasi A, Bellini N, Rawal D, Vora M, Makdissi A, Dhindsa S, Chaudhuri A, Dandona P 2011 Liraglutide as additional treatment for type 1 diabetes. Eur J Endocrinol 165:77-84
-
(2011)
Eur J Endocrinol
, vol.165
, pp. 77-84
-
-
Varanasi, A.1
Bellini, N.2
Rawal, D.3
Vora, M.4
Makdissi, A.5
Dhindsa, S.6
Chaudhuri, A.7
Dandona, P.8
-
25
-
-
0036020278
-
Hypoglycaemia: The limiting factor in the glycaemic management of Type I and Type II diabetes
-
DOI 10.1007/s00125-002-0822-9
-
Cryer PE 2002 Hypoglycaemia: the limiting factor in the glycaemic management of type I and type II diabetes. Diabetologia 45:937-948 (Pubitemid 34762188)
-
(2002)
Diabetologia
, vol.45
, Issue.7
, pp. 937-948
-
-
Cryer, P.E.1
-
26
-
-
79961191559
-
Regulation of glucagon secretion by incretins
-
Holst JJ, Christensen M, Lund A, de Heer J, Svendsen B, Kielgast U, Knop FK 2011 Regulation of glucagon secretion by incretins. Diabet Obes Metab 13(Suppl 1):89-94
-
(2011)
Diabet Obes Metab
, vol.13
, Issue.SUPPL. 1
, pp. 89-94
-
-
Holst, J.J.1
Christensen, M.2
Lund, A.3
De Heer, J.4
Svendsen, B.5
Kielgast, U.6
Knop, F.K.7
-
27
-
-
55649108863
-
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
-
de Heer J, Rasmussen C, Coy DH, Holst JJ 2008 Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas. Diabetologia 51:2263-2270
-
(2008)
Diabetologia
, vol.51
, pp. 2263-2270
-
-
De Heer, J.1
Rasmussen, C.2
Coy, D.H.3
Holst, J.J.4
-
28
-
-
56049086867
-
Insulin as a physiological modulator of glucagon secretion
-
Bansal P, Wang Q 2008 Insulin as a physiological modulator of glucagon secretion. Am J Physiol 295:E751-E761
-
(2008)
Am J Physiol
, vol.295
-
-
Bansal, P.1
Wang, Q.2
-
29
-
-
0030936890
-
Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycemia in women
-
Havel PJ, Ahrén B 1997 Activation of eutonomic nervous and the adrenal medula contributes to increased glucagon secretion during moderate insulin-induced hypoglycemia in women. Diabetes 46: 801-807 (Pubitemid 27188257)
-
(1997)
Diabetes
, vol.46
, Issue.5
, pp. 801-807
-
-
Havel, P.J.1
Ahren, B.2
-
30
-
-
84857401071
-
Minireview: The role of the autonomic nervous system in mediating the glucagon response to hypoglycemia
-
Taborsky Jr GJ, Mundinger TO 2012 Minireview: the role of the autonomic nervous system in mediating the glucagon response to hypoglycemia. Endocrinology 153:1055-1062
-
(2012)
Endocrinology
, vol.153
, pp. 1055-1062
-
-
Taborsky Jr., G.J.1
Mundinger, T.O.2
-
31
-
-
0017948650
-
Vagal, cholinergic regulation of pancreatic polypeptide secretion
-
Schwartz TW, Holst JJ, Fahrenkrug J, Jensen SL, Nielsen OV, Rehfeld JF, de Muckadell OB, Stadil F 1978 Vagal, cholinergic regulation of pancreatic polypeptide secretion. J Clin Invest 61:781-789
-
(1978)
J Clin Invest
, vol.61
, pp. 781-789
-
-
Schwartz, T.W.1
Holst, J.J.2
Fahrenkrug, J.3
Jensen, S.L.4
Nielsen, O.V.5
Rehfeld, J.F.6
De Muckadell, O.B.7
Stadil, F.8
-
32
-
-
0024157069
-
Glucose counterregulation and its impact on diabetes mellitus
-
Gerich JE 1988 Glucose counterregulation and its impact on diabetes mellitus. Diabetes 37:1608-1617 (Pubitemid 19004942)
-
(1988)
Diabetes
, vol.37
, Issue.12
, pp. 1608-1617
-
-
Gerich, J.E.1
-
33
-
-
2642593026
-
Autonomic mediation of glucagon secretion during hypoglycemia. Implications for impaired α-cell responses in type 1 diabetes
-
Taborsky Jr GJ, Ahrén B, Havel PJ 1988 Autonomic mediation of glucagon secretion during hypoglycemia. Implications for impaired α-cell responses in type 1 diabetes. Diabetes 47:995-1005
-
(1988)
Diabetes
, vol.47
, pp. 995-1005
-
-
Taborsky Jr., G.J.1
Ahrén, B.2
Havel, P.J.3
-
34
-
-
2442482515
-
Inhibition of Dipeptidyl Peptidase-4 Reduces Glycemia, Sustains Insulin Levels, and Reduces Glucagon Levels in Type 2 Diabetes
-
DOI 10.1210/jc.2003-031907
-
Ahrén B, Landin-Olsson M, Jansson PA, Svensson M, Holmes D, Schweizer A 2004 Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels and reduces glucagon levels in type 2 diabetes. J Clin Endocrinol Metab 89:2078-2084 (Pubitemid 38619835)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.5
, pp. 2078-2084
-
-
Ahren, B.1
Landin-Olsson, M.2
Jansson, P.-A.3
Svensson, M.4
Holmes, D.5
Schweizer, A.6
-
35
-
-
84985957320
-
Efficacy of vildagliptin therapy in combination with insulin in patients with type 2 diabetes and severe renal renal impairment
-
Lukashevich V, Schweizer A, Foley J, Shao Q, Groop PH, Kothny W 2011 Efficacy of vildagliptin therapy in combination with insulin in patients with type 2 diabetes and severe renal renal impairment. Diabetologia 54(Suppl 1):S332-S333
-
(2011)
Diabetologia
, vol.54
, Issue.SUPPL. 1
-
-
Lukashevich, V.1
Schweizer, A.2
Foley, J.3
Shao, Q.4
Groop, P.H.5
Kothny, W.6
|