Two immunogenic passenger dendritic cell subsets in the rat liver have distinct trafficking patterns and radiosensitivities

Hepatology

Volumn 56, Issue 4, 2012, Pages 1532-1545

  Yu, Bin ^a,b   Ueta, Hisashi ^a   Kitazawa, Yusuke ^a   Tanaka, Toshiya ^c   Adachi, Kensuke ^d   Kimura, Hiromitsu ^e   Morita, Miwa ^f   Sawanobori, Yasushi ^a   Qian, Hai Xin ^b   Kodama, Tatsuhiko ^c   Matsuno, Kenjiro ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c UNIVERSITY OF TOKYO   (Japan)

^d TOKYO METROPOLITAN TAMA MEDICAL CENTER   (Japan)

^e NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^f LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; CD11B ANTIGEN; CD86 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TRANSCRIPTION FACTOR FOXP3;

ACUTE GRAFT REJECTION; ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELL SUBPOPULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; IMMUNOGENICITY; LEUKOCYTE MIGRATION; LIVER CELL; LIVER GRAFT REJECTION; LIVER TRANSPLANTATION; LYMPHOID ORGAN; NONHUMAN; PARAAORTIC LYMPH NODE; PERITONEAL CAVITY; PRIORITY JOURNAL; RADIOSENSITIVITY; RAT; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; UPREGULATION;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; GRAFT REJECTION; IMMUNOHISTOCHEMISTRY; LIVER; LIVER TRANSPLANTATION; LYMPH NODES; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RADIATION TOLERANCE; RANDOM ALLOCATION; RATS; RATS, INBRED LEW; SENSITIVITY AND SPECIFICITY;

EID: 84867182447     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25795     Document Type: Article

References (30)

1. Heath WR, Carbone FR. Dendritic cell subsets in primary and secondary T cell responses at body surfaces. Nat Immunol 2009; 10: 1237-1244.
2. Matsuno K, Ezaki T, Kudo S, Uehara Y. A life stage of particle-laden rat dendritic cells in vivo: their terminal division, active phagocytosis, and translocation from the liver to the draining lymph. J Exp Med 1996; 183: 1865-1878.
3. Turnbull EL, Yrlid U, Jenkins CD, Macpherson GG. Intestinal dendritic cell subsets: differential effects of systemic TLR4 stimulation on migratory fate and activation in vivo. J Immunol 2005; 174: 1374-1384.
4. Kumamoto Y, Denda-Nagai K, Aida S, Higashi N, Irimura T. MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo. PLoS One 2009; 4: e5619.
5. Ginhoux F, Liu K, Helft J, Bogunovic M, Greter M, Hashimoto D, et al. The origin and development of nonlymphoid tissue CD103+ DCs. J Exp Med 2009; 206: 3115-3130.
6. Ueta H, Shi C, Miyanari N, Xu XD, Zhou S, Yamashita M, et al. Systemic transmigration of allosensitizing donor dendritic cells to host secondary lymphoid organs after rat liver transplantation. HEPATOLOGY 2008; 47: 1352-1362.
7. Lechler R, Ng WF, Steinman RM. Dendritic cells in transplantation-friend or foe? Immunity 2001; 14: 357-368.
8. Kudo S, Matsuno K, Ezaki T, Ogawa M. A novel migration pathway for rat dendritic cells from the blood: hepatic sinusoids-lymph translocation. J Exp Med 1997; 185: 777-784.
9. Matsuno K, Ezaki T. Dendritic cell dynamics in the liver and hepatic lymph. Int Rev Cytol 2000; 197: 83-136.
10. Matsuno K, Kudo S, Ezaki T, Miyakawa K. Isolation of dendritic cells in the rat liver lymph. Transplantation 1995; 60: 765-768.
11. Xu XD, Ueta H, Zhou S, Shi C, Koga D, Ushiki T, et al. Trafficking of recirculating lymphocytes in the rat liver: rapid transmigration into the portal area and then to the hepatic lymph. Liver Int 2008; 28: 319-330.
12. Yrlid U, Cerovic V, Milling S, Jenkins CD, Klavinskis LS, MacPherson GG. A distinct subset of intestinal dendritic cells responds selectively to oral TLR7/8 stimulation. Eur J Immunol 2006; 36: 2639-2648.
13. Tilney NL. Patterns of lymphatic drainage in the adult laboratory rat. J Anat 1971; 109: 369-383.
14. Abu-Hijleh MF, Habbal OA, Moqattash ST. The role of the diaphragm in lymphatic absorption from the peritoneal cavity. J Anat 1995; 186: 453-467.
15. Ezaki T, Kuwahara K, Morikawa S, Matsuno K, Sakaguchi N. Characterization of adjuvant-induced rat lymphangiomas as a model to study the lymph drainage from abdominal cavity. Jpn J Lymphol 2004; 27: 1-10.
16. Steer HW, Foot RA. Changes in the medulla of the parathymic lymph nodes of the rat during acute gastro-intestinal inflammation. J Anat 1987; 152: 23-36.
17. Sun J, McCaughan GW, Gallagher ND, Sheil AG, Bishop GA. Deletion of spontaneous rat liver allograft acceptance by donor irradiation. Transplantation 1995; 60: 233-236.
18. Zhou S, Ueta H, Xu XD, Shi C, Matsuno K. Predominant donor CD103+CD8+ T cell infiltration into the gut epithelium during acute GvHD: a role of gut lymph nodes. Int Immunol 2008; 20: 385-394.
19. Smilek DE, Boyd HC, Wilson DB, Zmijewski CM, Fitch FW, McKearn TJ. Monoclonal rat anti-major histocompatibility complex antibodies display specificity for rat, mouse, and human target cells. J Exp Med 1980; 151: 1139-1150.
20. Matsuno K, Ueta H, Shu Z, Xue-Dong X, Sawanobori Y, Kitazawa Y, et al. The microstructure of secondary lymphoid organs that support immune cell trafficking. Arch Histol Cytol 2010; 73: 1-21.
21. Ohtani O, Ohtani Y. Structure and function of rat lymph nodes. Arch Histol Cytol 2008; 71: 69-76.
22. Johnson D, Shah P, Collins P, Wigley C. Chest wall. In: Standring S, ed. Gray's Anatomy, 39th ed. New York: Elsevier; 2005: 964-966.
23. Fukao T, Koyasu S. Expression of functional IL-2 receptors on mature splenic dendritic cells. Eur J Immunol 2000; 30: 1453-1457.
24. Adachi K. A study for acquired transplantation tolerance using experimental rat liver transplantation model (PhD Thesis in Japanese). Ohmiya, Japan: Jichi Medical University; 2002.
25. Li Y, Zhao X, Cheng D, Haga H, Tsuruyama T, Wood K, et al. The presence of Foxp3 expressing T cells within grafts of tolerant human liver transplant recipients. Transplantation 2008; 86: 1837-1843.
26. Bishop GA, Wang C, Sharland AF, McCaughan G. Spontaneous acceptance of liver transplants in rodents: evidence that liver leucocytes induce recipient T-cell death by neglect. Immunol Cell Biol 2002; 80: 93-100.
27. Bowen DG, Zen M, Holz L, Davis T, McCaughan GW, Bertolino P. The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity. J Clin Invest 2004; 114: 701-712.
28. Morita M, Fujino M, Jiang G, Kitazawa Y, Xie L, Azuma M, et al. PD-1/B7-H1 interaction contribute to the spontaneous acceptance of mouse liver allograft. Am J Transplant 2010; 10: 40-46.
29. Ezzelarab M, Thomson AW. Tolerogenic dendritic cells and their role in transplantation. Semin Immunol 2011; 23: 252-263.
30. Sharland A, Yan Y, Wang C, Bowen DG, Sun J, Sheil AG, et al. Evidence that apoptosis of activated T cells occurs in spontaneous tolerance of liver allografts and is blocked by manipulations which break tolerance. Transplantation 1999; 68: 1736-1745.