Long-term outcomes of IgA nephropathy presenting with minimal or no proteinuria

Journal of the American Society of Nephrology

Volumn 23, Issue 10, 2012, Pages 1753-1760

  Gutieŕrez, Eduardo ^a   Zamora, Isabel ^b   Ballarín, JoséAntonio ^c   Arce, Yolanda ^c   Jimeńez, Sara ^d   Quereda, Carlos ^d   Olea, Teresa ^e   Martínez Ara, Jorge ^e   Segarra, Alfons ^f   Bernis, Carmen ^g   García, Asuncioń ^g   Goicoechea, Marian ^h   Garciá De Vinuesa, Soledad ^h   Rojas Rivera, Jorge ^a   Praga, Manuel ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

^c FUNDACIÓ PUIGVERT   (Spain)

^d HOSPITAL RAMÓN Y CAJAL   (Spain)

^e HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^f HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^g HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^h HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; CORTICOSTEROID; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IMMUNOSUPPRESSIVE AGENT;

ADOLESCENT; ADULT; AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; BLOOD SAMPLING; CAUCASIAN; CLINICAL FEATURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; FEMALE; FOCAL GLOMERULOSCLEROSIS; FOLLOW UP; HEMATURIA; HUMAN; HYPERTENSION; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOSUPPRESSIVE TREATMENT; INTERSTITIAL NEPHRITIS; KIDNEY BIOPSY; KIDNEY FAILURE; KIDNEY FUNCTION; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MICROSCOPY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; PROLIFERATIVE GLOMERULONEPHRITIS; PROPORTIONAL HAZARDS MODEL; PROTEINURIA; REMISSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RISK FACTOR; SENSITIVITY AND SPECIFICITY;

EID: 84867164317     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2012010063     Document Type: Article

References (30)

1. D'Amico G: Natural history of idiopathic IgA nephropathy: Role of clinical and histological prognostic factors. Am J Kidney Dis 36: 227-237, 2000
2. Alamartine E, Sabatier JC, Guerin C, Berliet JM, Berthoux F: Prognostic factors in mesangial IgA glomerulonephritis: An extensive study with univariate and multivariate analyses. Am J Kidney Dis 18: 12-19, 1991
3. Berthoux F, Mohey H, Laurent B, Mariat C, Afiani A, Thibaudin L: Predicting the risk for dialysis or death in IgA nephropathy. J Am Soc Nephrol 22: 752-761, 2011
4. Bartosik LP, Lajoie G, Sugar L, Cattran DC: Predicting progression in IgA nephropathy. Am J Kidney Dis 38: 728-735, 2001
5. Reich HN, Troyanov S, Scholey JW, Cattran DC; Toronto Glomerulonephritis Registry: Remission of proteinuria improves prognosis in IgA nephropathy. J Am Soc Nephrol 18: 3177-3183, 2007 (Pubitemid 350223978)
6. Barratt J, Feehally J: IgA nephropathy. J Am Soc Nephrol 16: 2088-2097, 2005 (Pubitemid 41716440)
7. Donadio JV, Bergstralh EJ, Grande JP, Rademcher DM: Proteinuria patterns and their association with subsequent end-stage renal disease in IgA nephropathy. Nephrol Dial Transplant 17: 1197-1203, 2002 (Pubitemid 34812063)
8. Coppo R, D'Amico G: Factors predicting progression of IgA nephropathies. J Nephrol 18: 503-512, 2005 (Pubitemid 41824469)
9. Roberts IS, Cook HT, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, Cattran DC, Coppo R, D'Agati V, D'Amico G, Emancipator S, Emma F, Feehally J, Ferrario F, Fervenza FC, Florquin S, Fogo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PK, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H; Working Group of the International IgA Nephropathy Network and the Renal Pathology Society: The Oxford classification of IgA nephropathy: Pathology definitions, correlations, and reproducibility. Kidney Int 76: 546-556, 2009
10. Working Group of the International IgA Nephropathy Network and the Renal Pathology SocietyCattran DC, Coppo R, Cook HT, Feehally J, Roberts IS, Troyanov S, Alpers CE, Amore A, Barrat J, Berthoux F, Bonsib S, Brujin JA, D'Agati V, D'Amico G, Emancipator S, Emma F, Ferrario F, Fervenza FC, Florquin S, Foggo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Leung CB, Li LS, Li PK, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H: The Oxford Classification of IgA nephropathy: Rationale, clinicopathological correlations, and clasification. Kidney Int 76: 534-545, 2009
11. Working Group of the International IgA Nephropathy Network and the Renal Pathology SocietyCoppo R, Troyanov S, Camilla R, Hogg RJ, Cattran DC, Cook HT, Feehally J, Roberts IS, Amore A, Alpers CE, Barrat J, Berthoux F, Bonsib S, Brujin JA, D'Agati V, D'Amico G, Emancipator SN, Emma F, Ferrario F, Fervenza FC, Florquin S, Fogo AB, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PK, Liu ZH, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H: The Oxford IgA nephropahty clinicopathological classi fi cation is valid for children as well as adults. Kidney Int 77: 921-927, 2010
12. Lai FM, Szeto CC, Choi PC, Li PK, Chan AW, Tang NL, Lui SF, Wang AY, To KF: Characterization of early IgA nephropathy. Am J Kidney Dis 36: 703-708, 2000
13. Szeto CC, Lai FM, To KF, Wong TY, Chow KM, Choi PC, Lui SF, Li PK: The natural history of immunoglobulin a nephropathy among patients with hematuria and minimal proteinuria. Am J Med 110: 434-437, 2001
14. Li PK, Ho KK, Szeto CC, Yu L, Lai FM: Prognostic indicators of IgA nephropathy in the Chinese-clinical and pathological perspectives. Nephrol Dial Transplant 17: 64-69, 2002 (Pubitemid 34093011)
15. Shen P, He L, Huang D: Clinical course and prognostic factors of clinical early IgA nephropathy. Neth J Med 66: 242-247, 2008 (Pubitemid 351935809)
16. Koyama A, Igarashi M, Kobayashi M; Research Group on Progressive Renal Diseases: Natural history and risk factors for immunoglobulin A nephropathy in Japan. Am J Kidney Dis 29: 526-532, 1997 (Pubitemid 27155272)
17. Costa RS, Droz D, Noel LH: Long-standing spontaneous clinical remission and glomerular improvement in primary IgA nephropathy (Berger's disease). Am J Nephrol 7: 440-444, 1987 (Pubitemid 18025637)
18. Alamartine E, Sabatier JC, Berthoux FC: Comparison of pathological lesions on repeated renal biopsies in 73 patients with primary IgA glomerulonephritis: Value of quantitative scoring and approach to final prognosis. Clin Nephrol 34: 45-51, 1990 (Pubitemid 20257883)
19. Praga M, Gutiérrez E, González E, Morales E, Hernández E: Treatment of IgA nephropathy with ACE inhibitors: A randomized and controlled trial. J Am Soc Nephrol 14: 1578-1583, 2003 (Pubitemid 36687059)
20. Praga M, Hernández E, Montoyo C, Andrés A, Ruilope LM, Rodicio JL: Long-term bene ficial effects of angiotensin-converting enzyme inhibition in patients with nephrotic proteinuria. Am J Kidney Dis 20: 240-248, 1992
21. Cattran DC, Greenwood C, Ritchie S: Long-term benefits of angiotensin-converting enzyme inhibitor therapy in patients with severe immunoglobulin a nephropathy: A comparison to patients receiving treatment with other antihypertensive agents and to patients receiving no therapy. Am J Kidney Dis 23: 247-254, 1994 (Pubitemid 24075319)
22. Coppo R, Peruzzi L, Amore A, Piccoli A, Cochat P, Stone R, Kirschstein M, Linné T: IgACE: A placebo-controlled, randomized trial of angiotensin-converting enzyme inhibitors in children and young people with IgA nephropathy and moderate proteinuria. J Am Soc Nephrol 18: 1880-1888, 2007 (Pubitemid 46870324)
23. Bonnet F, Deprele C, Sassolas A, Moulin P, Alamartine E, Berthezène F, Berthoux F: Excessive body weight as a new independent risk factor for clinical and pathological progression in primary IgA nephritis. Am J Kidney Dis 37: 720-727, 2001 (Pubitemid 32268032)
24. Tanaka M, Tsujii T, Komiya T, Iwasaki Y, Sugishita T, Yonemoto S, Tsukamoto T, Fukui S, Takasu A, Muso E: Clinicopathological influence of obesity in IgA nephropathy: Comparative study of 74 patients. Contrib Nephrol 157: 90-93, 2007
25. Appel GB, Waldman M: The IgA nephropathy treatment dilemma. Kidney Int 69: 1939-1944, 2006 (Pubitemid 43924256)
26. Eitner F, Ackermann D, Hilgers RD, Floege J: Supportive Versus Immunosuppressive Therapy of Progressive IgA nephropathy (STOP) IgAN trial: Rationale and study protocol. J Nephrol 21: 284-289, 2008
27. Floege J, Eitner F: Current therapy for IgA nephropathy. J Am Soc Nephrol 22: 1785-1794, 2011
28. Feehally J, Farrall M, Boland A, Gale DP, Gut I, Heath S, Kumar A, Peden JF, Maxwell PH, Morris DL, Padmanabhan S, Vyse TJ, Zawadzka A, Rees AJ, Lathrop M, Ratcliffe PJ: HLA has strongest association with IgA nephropathy in genome-wide analysis. J Am Soc Nephrol 21: 1791-1797, 2010
29. Gharavi AG, Kiryluk K, Choi M, Li Y, Hou P, Xie J, Sanna-Cherchi S, Men CJ, Julian BA, Wyatt RJ, Novak J, He JC, Wang H, Lv J, Zhu L, Wang W, Wang Z, Yasuno K, Gunel M, Mane S, Umlauf S, Tikhonova I, Beerman I, Savoldi S, Magistroni R, Ghiggeri GM, Bodria M, Lugani F, Ravani P, Ponticelli C, Allegri L, Boscutti G, Frasca G, Amore A, Peruzzi L, Coppo R, Izzi C, Viola BF, Prati E, Salvadori M, Mignani R, Gesualdo L, Bertinetto F, Mesiano P, Amoroso A, Scolari F, Chen N, Zhang H, Lifton RP: Genome-wide association study identifies susceptibility loci for IgA nephropathy. Nat Genet 43: 321-327, 2011
30. Praga M: New insights into familial microhematuria. Curr Opin Nephrol Hypertens 8: 173-177, 1999