Adverse health effects of child labor: High exposure to chromium and oxidative DNA damage in children manufacturing surgical instruments

Environmental Health Perspectives

Volumn 120, Issue 10, 2012, Pages 1469-1474

  Sughis, Muhammad ^a,b,c   Nawrot, Tim S ^a,d   Haufroid, Vincent ^e   Nemery, Benoit ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Centre of Research for Public Health   (Pakistan)

^c Lahore College of Pharmaceutical Sciences   (Pakistan)

^d HASSELT UNIVERSITY   (Belgium)

^e UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Metal exposure; Nickel; Oxidative DNA damage; Pakistan; Sialkot; Surgical instruments

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ALUMINUM; ANTIMONY; ARSENIC; BARIUM; CADMIUM; CHROMIUM; COPPER; CREATININE; LEAD; MANGANESE; MOLYBDENUM; NICKEL; SELENIUM; URANIUM; VANADIUM; ZINC;

ADOLESCENT; ANTHROPOMETRIC PARAMETERS; ARTICLE; ASTHMA; BIOLOGICAL MONITORING; BLOOD PRESSURE; CHILD; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; PAKISTAN; PRIORITY JOURNAL; QUESTIONNAIRE; SCHOOL CHILD; SPIROMETRY; SURGICAL INSTRUMENT; WORK ENVIRONMENT;

ADOLESCENT; AIR POLLUTANTS, OCCUPATIONAL; BIOLOGICAL MARKERS; BLOOD PRESSURE; CARCINOGENS; CHILD; CHROMIUM; CROSS-SECTIONAL STUDIES; DEOXYGUANOSINE; DNA DAMAGE; ENVIRONMENTAL MONITORING; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INDUSTRY; MALE; MASS SPECTROMETRY; NICKEL; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; PAKISTAN; QUESTIONNAIRES; RESPIRATORY FUNCTION TESTS; RESPIRATORY TRACT DISEASES; SEASONS; SPIROMETRY; SURGICAL INSTRUMENTS;

EID: 84867161125     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1104678     Document Type: Article

References (36)

1. American Conference of Governmental Industrial Hygienists. 2006. TLVs and BEIs: Based on the Documentation of the Threshold Limit Values for Chemical Substances and Physical Agents & Biological Exposure Indices. Cincinnati, OH: American Conference of Governmental Industrial Hygienists.
2. Arets HGM, Brackel HJL, van der Ent CK. 2001. Forced expiratory manoeuvres in children: do they meet ATS and ERS criteria for spirometry? Eur Respir J 18:655-660.
3. Banza CLN, Nawrot TS, Haufroid V, Decrée S, De Putter T, Smolders E, et al. 2009. High human exposure to cobalt and other metals in Katanga, a mining area of the Democratic Republic of Congo. Environ Res 109:745-752.
4. Bhutta MF. 2006. Fair trade for surgical instruments. BMJ 333:297-299.
5. Bhutta MF. 2008. Fair and ethical trade in health procurement. Lancet 372:1935-1937.
6. Boskabady MH, Tashakory A, Mazloom R, Ghamami G. 2004. Prediction equations for pulmonary function values in healthy young Iranians aged 8-18 years. Respirology 9:535-542.
7. Centers for Disease Control and Prevention. 2009. Fourth National Report on Human Exposure to Environmental Chemicals. Available: http://www.cdc.gov/ExposureReport/pdf/FourthReport.pdf [accessed 29 October 2011].
8. Centre for the Improvement of Working Conditions and Environment. 2003. Annual Report of Activities, 2003. Available: http://www.ciwce.org.pk/Publications/Annual_Reports/Annual_Report_2003.pdf [accessed 23 January 2012].
9. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, et al. 2003. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure-the JNC 7 report. JAMA 289:2560-2572.
10. Cocker J, Mason HJ, Warren ND, Cotton RJ. 2011. Creatinine adjustment of biological monitoring results. Occup Med 61:349-353.
11. Federal Bureau of Statistics. 1996. Summary results of child labour survey in Pakistan. Islamabad:Ministry of Labour, Manpower and Overseas Pakistanis. Availbale: http://www.ilo.org/legacy/english/regions/asro/newdelhi/ipec/download/resources/pakistan/pakpubl96eng7.pdf [accessed 13 February 2011].
12. Gulson BL, Cameron MA, Smith AJ, Mizon KJ, Korsch MJ, Vimpani G, et al. 1998. Blood lead-urine lead relationships in adults and children. Environ Res 78:152-160.
13. ILO (International Labor Organization). 2004. Baseline Survey Report on Child Labour in Surgical Instruments Manufacturing Industry Sialkot. 2004. A report submitted by AKIDA Management Consultants, Lahore, Pakistan. Available: www.ilo.org/ipecinfo/product/download.do?type=document&id=5228 [accessed 23 January 2012].
14. ILO (International Labor Organization). 2011. Children in Hazardous Work: What We Know, What We Need to Do. Available: http://www.ilo.org/wcmsp5/groups/public/@dgreports/@dcomm/@publ/documents/publication/wcms_155428.pdf [accessed 23 August 2011].
15. International Agency for Research on Cancer. 1990. Chromium, nickel and welding. IARC Monogr Eval Carcinog Risks Hum 49. Available: http://monographs.iarc.fr/ENG/Monographs/vol49/mono49.pdf [accessed 14 October 2011].
16. ISAAC (International Study of Asthma and Allergies in Childhood). 2004. Phase Three Manual. ISAAC International Data Centre, Auckland, New Zealand. Available: http://isaac.auckland.ac.nz/phases/phasethree/phasethreemanual.pdf [accessed 16 March 2011].
17. Klein C, Costa M. 2007. Nickel. In: Handbook on the Toxicology of Metals. 3rd ed. (Nordberg GF, Fowler BA, Nordberg M, Friberg LT, eds). San Diego:Academic Press, 743-758.
18. Landrigan PJ, Goldman LR. 2011. Children's vulnerability to toxic chemicals: a challenge and opportunity to strengthen health and environmental policy. Health Aff 30:842-850.
19. Langård S, Costa M. 2007. Chromium. In: Handbook on the Toxicology of Metals. 3rd ed. (Nordberg GF, Fowler BA, Nordberg M, Friberg LT, eds). San Diego:Academic Press, 487-510.
20. Lauwerys RL, Hoet P. 1993. Industrial Chemical Exposure: Guidelines for Biological Monitoring. 2nd ed. Boca Raton, FL:Lewis Publishers.
21. Malik RN, Jadoon WA, Husain SZ. 2010. Metal contamination of surface soils of industrial city Sialkot, Pakistan: a multivariate and GIS approach. Environ Geochem Health 32:179-191.
22. Marnett LJ. 2000. Oxyradicals and DNA damage. Carcinogenesis 21:361-370.
23. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, et al. 2005. Standardisation of spirometry. Eur Respir J 26:319-338.
24. Nawrot TS, Thijs L, Den Hond EM, Roels HA, Staessen JA. 2002. An epidemiological re-appraisal of the association between blood pressure and blood lead: a meta-analysis. J Hum Hypertens 16:123-131.
25. Nemery B, Casier P, Roosels D, Lahaye D, Demedts M. 1992. Survey of cobalt exposure and respiratory health in diamond polishers. Am Rev Respir Dis 145:610-616.
26. Ng'Ang'a LW, Ernst P, Jaakkola MS, Gerardi G, Hanley JH, Becklake MR. 1992. Spirometric lung function. Distribution and determinants of test failure in a young adult population. Am Rev Respir Dis 145:48-52.
27. O'Brien E, Asmar R, Beilin L, Imai Y, Mallion JM, Mancia G, et al. 2003. European Society of hypertension recommendations for conventional, ambulatory and home blood pressure measurement. J Hypertens 21:821-848.
28. Paschal DC, Ting BG, Morrow JC, Pirkle JL, Jackson RJ, Sampson EJ, et al. 1998. Trace metals in urine of United States residents: reference range concentrations. Environ Res 76:53-59.
29. Pearce N, Checkoway H, Kriebel D. 2007. Bias in occupational epidemiology studies. Occup Environ Med 64:562-568.
30. Staessen JA, Nawrot T, Den Hond E, Thijs L, Fagard R, Hoppenbrouwers K, et al. 2001. Renal function, cytogenetic measurements, and sexual development in adolescents in relation to environmental pollutants: a feasibility study of biomarkers. Lancet 357:1660-1669.
31. Tsuzuki T, Nakatsu Y, Nakabeppu Y. 2007. Significance of erroravoiding mechanisms for oxidative DNA damage in carcinogenesis. Cancer Sci 98:465-470.
32. Valavanidis A, Vlachogianni T, Fiotakis C. 2009. 8-hydroxy-2 ́-deoxyguanosine (8-OHdG): a critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 27:120-139.
33. Wong RH, Kuo CY, Hsu ML, Wang TY, Chang PI, Wu TH, et al. 2005. Increased levels of 8-hydroxy-2'-deoxyguanosine attributable to carcinogenic metal exposure among schoolchildren. Environ Health Perspect 113:1386-1390.
34. World Medical Association. 2008. Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects. Available: http://www.wma.net/en/30publications/10policies/b3/index.html [accessed 21 August 2012].
35. Zanconato S. 2005. Office spirometry in primary care pediatrics: a pilot study. Pediatrics 116:e792-e797.
36. Zapletal A, Paul T, Samánek M. 1977. Significance of contemporary methods of lung function testing for the detection of airway obstruction in children and adolescents. Z Erkr Atmungsorgane 149:343-371.