메뉴 건너뛰기




Volumn 51, Issue 3, 2012, Pages 336-341

Extending platinum-free interval in partially platinum-sensitive recurrent ovarian cancer by a non-platinum regimen: Its possible clinical significance

Author keywords

Partially platinum sensitive; Platinum sensitivity; Progression free interval; Recurrent ovarian cancer

Indexed keywords

CARBOPLATIN; DOXORUBICIN; GEMCITABINE; PACLITAXEL; PLATINUM DERIVATIVE; TRABECTEDIN;

EID: 84867142221     PISSN: 10284559     EISSN: 18756263     Source Type: Journal    
DOI: 10.1016/j.tjog.2012.07.003     Document Type: Review
Times cited : (17)

References (49)
  • 1
    • 33751365495 scopus 로고    scopus 로고
    • Survival benefits with diverse chemotherapy regimens for ovarian cancer: meta-analysis of multiple treatments
    • Kyrgiou M., Salanti G., Pavlidis N., Paraskevaidis E., Ioannidis J.P. Survival benefits with diverse chemotherapy regimens for ovarian cancer: meta-analysis of multiple treatments. J Natl Cancer Inst 2006, 98:1655-1663.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 1655-1663
    • Kyrgiou, M.1    Salanti, G.2    Pavlidis, N.3    Paraskevaidis, E.4    Ioannidis, J.P.5
  • 2
    • 0024522049 scopus 로고
    • Response of patients in phase II studies of chemotherapy in ovarian cancer: implications for patient treatment and the design of phase II trials
    • Blackledge G., Lawton F., Redman C., Kelly K. Response of patients in phase II studies of chemotherapy in ovarian cancer: implications for patient treatment and the design of phase II trials. Br J Cancer 1989, 59:650-653.
    • (1989) Br J Cancer , vol.59 , pp. 650-653
    • Blackledge, G.1    Lawton, F.2    Redman, C.3    Kelly, K.4
  • 3
    • 0025103224 scopus 로고
    • Treatment of relapsed carcinoma of the ovary with cisplatin or carboplatin following initial treatment with these compounds
    • Gore M.E., Fryatt I., Wiltshaw E., Dawson T. Treatment of relapsed carcinoma of the ovary with cisplatin or carboplatin following initial treatment with these compounds. Gynecol Oncol 1990, 36:207-211.
    • (1990) Gynecol Oncol , vol.36 , pp. 207-211
    • Gore, M.E.1    Fryatt, I.2    Wiltshaw, E.3    Dawson, T.4
  • 4
    • 0026086870 scopus 로고
    • Second-line platinum therapy in patients with ovarian cancer previously treated with cisplatin
    • Markman M., Rothman R., Hakes T., Reichman B., Hoskins W., Rubin S., et al. Second-line platinum therapy in patients with ovarian cancer previously treated with cisplatin. J Clin Oncol 1991, 9:389-393.
    • (1991) J Clin Oncol , vol.9 , pp. 389-393
    • Markman, M.1    Rothman, R.2    Hakes, T.3    Reichman, B.4    Hoskins, W.5    Rubin, S.6
  • 6
    • 0032910470 scopus 로고    scopus 로고
    • Extending the platinum-free interval in recurrent ovarian cancer: the role of topotecan in second-line chemotherapy
    • Bookman M.A. Extending the platinum-free interval in recurrent ovarian cancer: the role of topotecan in second-line chemotherapy. Oncologist 1999, 4:87-94.
    • (1999) Oncologist , vol.4 , pp. 87-94
    • Bookman, M.A.1
  • 7
    • 0037033709 scopus 로고    scopus 로고
    • Weekly platinum chemotherapy for recurrent ovarian cancer
    • Clamp A., Jayson G.C. Weekly platinum chemotherapy for recurrent ovarian cancer. Br J Cancer 2002, 86:2-4.
    • (2002) Br J Cancer , vol.86 , pp. 2-4
    • Clamp, A.1    Jayson, G.C.2
  • 9
    • 79960055151 scopus 로고    scopus 로고
    • Introduction. Trabectedin treatment in GYN cancers
    • Poveda A. Introduction. Trabectedin treatment in GYN cancers. Int J Gynecol Cancer 2011, 21:S1-S2.
    • (2011) Int J Gynecol Cancer , vol.21
    • Poveda, A.1
  • 10
    • 84857594981 scopus 로고    scopus 로고
    • Trabectedin plus pegylated liposomal doxorubicin in the treatment of patients with partially platinum-sensitive ovarian cancer: current evidence and future perspectives
    • Sehouli J., Alfaro V., González-Martín A. Trabectedin plus pegylated liposomal doxorubicin in the treatment of patients with partially platinum-sensitive ovarian cancer: current evidence and future perspectives. Annals of Oncology 2012, 23:556-562.
    • (2012) Annals of Oncology , vol.23 , pp. 556-562
    • Sehouli, J.1    Alfaro, V.2    González-Martín, A.3
  • 11
    • 33846859308 scopus 로고    scopus 로고
    • Management strategies for partially platinum-sensitive ovarian cancer
    • Ledermann J.A., Raja F. Management strategies for partially platinum-sensitive ovarian cancer. Am J Cancer 2006, 5:341-354.
    • (2006) Am J Cancer , vol.5 , pp. 341-354
    • Ledermann, J.A.1    Raja, F.2
  • 12
    • 84857514950 scopus 로고    scopus 로고
    • Optimizing management of recurrent epithelial ovarian cancer with non-platinum-based chemotherapy
    • Pujade-Lauraine E., Vergote I., Pignata S., Kristensen G. Optimizing management of recurrent epithelial ovarian cancer with non-platinum-based chemotherapy. Clin Ovarian Cancer 2008, 1:139-140.
    • (2008) Clin Ovarian Cancer , vol.1 , pp. 139-140
    • Pujade-Lauraine, E.1    Vergote, I.2    Pignata, S.3    Kristensen, G.4
  • 13
    • 0037862963 scopus 로고    scopus 로고
    • Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer; the ICON4/AGO-OVAR-2.2 trial
    • Parmar M.K., Ledermann J.A., Colombo N., du Bois A., Delaloye J.F., Kristensen G.B., et al. Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer; the ICON4/AGO-OVAR-2.2 trial. Lancet 2003, 361:2099-2106.
    • (2003) Lancet , vol.361 , pp. 2099-2106
    • Parmar, M.K.1    Ledermann, J.A.2    Colombo, N.3    du Bois, A.4    Delaloye, J.F.5    Kristensen, G.B.6
  • 14
    • 40249100133 scopus 로고    scopus 로고
    • Management of partially platinum-sensitive relapsed ovarian cancer
    • Kaye S.B. Management of partially platinum-sensitive relapsed ovarian cancer. Eur J Cancer Suppl 2008, 6:16-21.
    • (2008) Eur J Cancer Suppl , vol.6 , pp. 16-21
    • Kaye, S.B.1
  • 15
    • 33646726747 scopus 로고    scopus 로고
    • Management of platinum-sensitive recurrent ovarian cancer
    • Pfisterer J., Ledermann J.A. Management of platinum-sensitive recurrent ovarian cancer. Semin Oncol 2006, 33:S12-S16.
    • (2006) Semin Oncol , vol.33
    • Pfisterer, J.1    Ledermann, J.A.2
  • 16
    • 78249288754 scopus 로고    scopus 로고
    • Platinum-sensitive relapsed epithelial ovarian cancer: not all the patients benefit from reinduction with carboplatin and paclitaxel
    • Milović-Kovačević M., Stamatovic L., Popov I., Radošević-Jelić L., Kezic I. Platinum-sensitive relapsed epithelial ovarian cancer: not all the patients benefit from reinduction with carboplatin and paclitaxel. Med Sci Monit 2010, 16:CR549-CR554.
    • (2010) Med Sci Monit , vol.16
    • Milović-Kovačević, M.1    Stamatovic, L.2    Popov, I.3    Radošević-Jelić, L.4    Kezic, I.5
  • 17
    • 33750588670 scopus 로고    scopus 로고
    • Gemcitabine plus carboplatin compared with carboplatin in patients with platinum-sensitive recurrent ovarian cancer: an Intergroup trial of the AGO-OVAR, and the NCIC CTG, and the EORTC GCG
    • Pfisterer J., Plante M., Vergote I., du Bois A., Hirte H., Lacave A.J., et al. Gemcitabine plus carboplatin compared with carboplatin in patients with platinum-sensitive recurrent ovarian cancer: an Intergroup trial of the AGO-OVAR, and the NCIC CTG, and the EORTC GCG. J Clin Oncol 2006, 24:4699-4707.
    • (2006) J Clin Oncol , vol.24 , pp. 4699-4707
    • Pfisterer, J.1    Plante, M.2    Vergote, I.3    du Bois, A.4    Hirte, H.5    Lacave, A.J.6
  • 18
    • 77954726606 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin and carboplatin compared with paclitaxel and carboplatin for patients with platinum-sensitive ovarian cancer in late relapse
    • Pujade-Lauraine E., Wagner U., Aavall-Lundqvist E., Gebski V., Heywood M., Vasey P.A., et al. Pegylated liposomal doxorubicin and carboplatin compared with paclitaxel and carboplatin for patients with platinum-sensitive ovarian cancer in late relapse. J Clin Oncol 2010, 28:3323-3329.
    • (2010) J Clin Oncol , vol.28 , pp. 3323-3329
    • Pujade-Lauraine, E.1    Wagner, U.2    Aavall-Lundqvist, E.3    Gebski, V.4    Heywood, M.5    Vasey, P.A.6
  • 19
    • 37349126263 scopus 로고    scopus 로고
    • Randomized trial of pegylated liposomal doxorubicin (PLD) plus carboplatin versus carboplatin in platinum-sensitive (PS) patients with recurrent epithelial ovarian or peritoneal carcinoma after failure of initial platinum-based chemotherapy (Southwest Oncology Group Protocol S0200)
    • Alberts D.S., Liu P.Y., Wilczynski S.P., Clouser M.C., Lopez A.M., Michelin D.P., et al. Randomized trial of pegylated liposomal doxorubicin (PLD) plus carboplatin versus carboplatin in platinum-sensitive (PS) patients with recurrent epithelial ovarian or peritoneal carcinoma after failure of initial platinum-based chemotherapy (Southwest Oncology Group Protocol S0200). Gynecol Oncol 2008, 108:90-94.
    • (2008) Gynecol Oncol , vol.108 , pp. 90-94
    • Alberts, D.S.1    Liu, P.Y.2    Wilczynski, S.P.3    Clouser, M.C.4    Lopez, A.M.5    Michelin, D.P.6
  • 20
    • 70349246454 scopus 로고    scopus 로고
    • Phase II study of pegylated liposomal doxorubicin and carboplatin in patients with platinum-sensitive and partially platinum-sensitive metastatic ovarian cancer
    • Rapoport B.L., Vorobiof D.A., Slabber C., Alberts A.S., Hlophe H.S., Mohammed C. Phase II study of pegylated liposomal doxorubicin and carboplatin in patients with platinum-sensitive and partially platinum-sensitive metastatic ovarian cancer. Int J Gynecol Cancer 2009, 19:1137-1141.
    • (2009) Int J Gynecol Cancer , vol.19 , pp. 1137-1141
    • Rapoport, B.L.1    Vorobiof, D.A.2    Slabber, C.3    Alberts, A.S.4    Hlophe, H.S.5    Mohammed, C.6
  • 21
    • 83055191407 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin combined with carboplatin: a rational treatment choice for advanced ovarian cancer
    • Pignata S., Lauraine E.P., du Bois A., Pisano C. Pegylated liposomal doxorubicin combined with carboplatin: a rational treatment choice for advanced ovarian cancer. Crit Rev Oncol Hematol 2010, 73:23-30.
    • (2010) Crit Rev Oncol Hematol , vol.73 , pp. 23-30
    • Pignata, S.1    Lauraine, E.P.2    du Bois, A.3    Pisano, C.4
  • 22
    • 33847304901 scopus 로고    scopus 로고
    • Second-line chemotherapy with pegylated liposomal doxorubicin and carboplatin is highly effective in patients with advanced ovarian cancer in late relapse: a GINECO phase II trial
    • Ferrero J.M., Weber B., Geay J.F., Lepille D., Orfeuvre H., Combe M., et al. Second-line chemotherapy with pegylated liposomal doxorubicin and carboplatin is highly effective in patients with advanced ovarian cancer in late relapse: a GINECO phase II trial. Ann Oncol 2007, 18(2):263-268.
    • (2007) Ann Oncol , vol.18 , Issue.2 , pp. 263-268
    • Ferrero, J.M.1    Weber, B.2    Geay, J.F.3    Lepille, D.4    Orfeuvre, H.5    Combe, M.6
  • 23
    • 78650392836 scopus 로고    scopus 로고
    • 18LBA. A GCIG randomized phase III study of carboplatin (C) & pegylated liposomal doxorubicin (PLD) (C-D) vs carboplatin (C) & paclitaxel (P) (C-P): CALYPSO results in partially platinum-sensitive ovarian cancer (OC) patients
    • Vasey P., Largillier R., Gropp M., Gebski V., Sandvei R., Elit L., et al. 18LBA. A GCIG randomized phase III study of carboplatin (C) & pegylated liposomal doxorubicin (PLD) (C-D) vs carboplatin (C) & paclitaxel (P) (C-P): CALYPSO results in partially platinum-sensitive ovarian cancer (OC) patients. Eur J Cancer Suppl 2009, 7:11.
    • (2009) Eur J Cancer Suppl , vol.7 , pp. 11
    • Vasey, P.1    Largillier, R.2    Gropp, M.3    Gebski, V.4    Sandvei, R.5    Elit, L.6
  • 24
    • 67651149486 scopus 로고    scopus 로고
    • Efficacy of pegylated liposomal doxorubicin (PLD) plus carboplatin in ovarian cancer patients who recur within six to twelve months: a phase II study
    • Power P., Stuart G., Oza A., Provencher D., Bentley J.R., Miller W.H., et al. Efficacy of pegylated liposomal doxorubicin (PLD) plus carboplatin in ovarian cancer patients who recur within six to twelve months: a phase II study. Gynecol Oncol 2009, 114:410-414.
    • (2009) Gynecol Oncol , vol.114 , pp. 410-414
    • Power, P.1    Stuart, G.2    Oza, A.3    Provencher, D.4    Bentley, J.R.5    Miller, W.H.6
  • 25
    • 84860470644 scopus 로고    scopus 로고
    • Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in partially platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial
    • Gladieff L., Ferrero A., De Rauglaudre G., Brown C., Vasey P., Reinthaller A., et al. Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in partially platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial. Annals of Oncology 2012, 23:1185-1189.
    • (2012) Annals of Oncology , vol.23 , pp. 1185-1189
    • Gladieff, L.1    Ferrero, A.2    De Rauglaudre, G.3    Brown, C.4    Vasey, P.5    Reinthaller, A.6
  • 26
    • 77950349922 scopus 로고    scopus 로고
    • Changing the paradigm in the treatment of platinum-sensitive recurrent ovarian cancer: from platinum doublets to nonplatinum doublets and adding antiangiogenesis compounds
    • Monk B.J., Coleman R.L. Changing the paradigm in the treatment of platinum-sensitive recurrent ovarian cancer: from platinum doublets to nonplatinum doublets and adding antiangiogenesis compounds. Int J Gynecol Cancer 2009, 19:S63-S67.
    • (2009) Int J Gynecol Cancer , vol.19
    • Monk, B.J.1    Coleman, R.L.2
  • 27
    • 0035879099 scopus 로고    scopus 로고
    • Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan
    • Gordon A.N., Fleagle J.T., Guthrie D., Parkin D.E., Gore M.E., Lacave A.J. Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan. J Clin Oncol 2001, 19:3312-3322.
    • (2001) J Clin Oncol , vol.19 , pp. 3312-3322
    • Gordon, A.N.1    Fleagle, J.T.2    Guthrie, D.3    Parkin, D.E.4    Gore, M.E.5    Lacave, A.J.6
  • 28
    • 4644225190 scopus 로고    scopus 로고
    • Long-term survival advantage for women treated with pegylated liposomal doxorubicin compared with topotecan in a phase 3 randomized study of recurrent and refractory epithelial ovarian cancer
    • Doxil Study 30-49 Investigators
    • Gordon A.N., Tonda M., Sun S., Rackoff W., Doxil Study 30-49 Investigators Long-term survival advantage for women treated with pegylated liposomal doxorubicin compared with topotecan in a phase 3 randomized study of recurrent and refractory epithelial ovarian cancer. Gynecol Oncol 2004, 95:1-8.
    • (2004) Gynecol Oncol , vol.95 , pp. 1-8
    • Gordon, A.N.1    Tonda, M.2    Sun, S.3    Rackoff, W.4
  • 29
    • 34848917530 scopus 로고    scopus 로고
    • Treatment of recurrent ovarian cancer relapsing 6-12 months post platinum-based chemotherapy
    • Colombo N., Gore M. Treatment of recurrent ovarian cancer relapsing 6-12 months post platinum-based chemotherapy. Crit Rev Oncol/Hematol 2007, 64:129-138.
    • (2007) Crit Rev Oncol/Hematol , vol.64 , pp. 129-138
    • Colombo, N.1    Gore, M.2
  • 30
    • 84891745161 scopus 로고    scopus 로고
    • National Institute for Health and Clinical Excellence (NICE) guidance. TA91 ovarian cancer (advanced) - paclitaxel
    • Available from: [accessed 02.01.12]
    • National Institute for Health and Clinical Excellence (NICE) guidance. TA91 ovarian cancer (advanced) - paclitaxel, pegylated liposomal doxorubicin hydrochloride and topotecan (review): Guidance. Available from: [accessed 02.01.12]. http://www.nice.org.uk/nicemedia/live/11554/33024/33024.pdf.
    • pegylated liposomal doxorubicin hydrochloride and topotecan (review): Guidance
  • 31
    • 84891739953 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network
    • Ovarian cancer Version 2.2012. Available from: [accessed 02.01.12]
    • National Comprehensive Cancer Network. (NCCN) clinical practice guidelines in oncology. Ovarian cancer Version 2.2012. Available from: [accessed 02.01.12]. http://www.nccn.org/professionals/physician_gls/PDF/ovarian.pdf.
    • (NCCN) clinical practice guidelines in oncology
  • 32
    • 3242686319 scopus 로고    scopus 로고
    • The role of topotecan for extending the platinum free interval in recurrent ovarian cancer: an in vitro model
    • Horowitz N.S., Hua J., Gibb R.K., Mutch D.G., Herzog T.J. The role of topotecan for extending the platinum free interval in recurrent ovarian cancer: an in vitro model. Gynecol Oncol 2004, 94:67-73.
    • (2004) Gynecol Oncol , vol.94 , pp. 67-73
    • Horowitz, N.S.1    Hua, J.2    Gibb, R.K.3    Mutch, D.G.4    Herzog, T.J.5
  • 33
    • 0029067168 scopus 로고
    • Carboplatin reinduction after taxane in patients with platinum-refractory epithelial ovarian cancer
    • Kavanagh J., Tresukosol D., Edwards C., Freedman R., Gonzalez de Leon C., Fishman A., et al. Carboplatin reinduction after taxane in patients with platinum-refractory epithelial ovarian cancer. J Clin Oncol 1995, 13:1584-1588.
    • (1995) J Clin Oncol , vol.13 , pp. 1584-1588
    • Kavanagh, J.1    Tresukosol, D.2    Edwards, C.3    Freedman, R.4    Gonzalez de Leon, C.5    Fishman, A.6
  • 34
    • 15444375395 scopus 로고    scopus 로고
    • Retrospective review: re-treatment of patients with ovarian cancer with carboplatin after platinum resistance
    • See H.T., Freedman R.S., Kudelka A.P., Burke T.W., Gershenson D.M., Tangjitgamol S., et al. Retrospective review: re-treatment of patients with ovarian cancer with carboplatin after platinum resistance. Int J Gynecol Cancer 2005, 15:209-216.
    • (2005) Int J Gynecol Cancer , vol.15 , pp. 209-216
    • See, H.T.1    Freedman, R.S.2    Kudelka, A.P.3    Burke, T.W.4    Gershenson, D.M.5    Tangjitgamol, S.6
  • 35
    • 35348841132 scopus 로고    scopus 로고
    • Extending the platinum-free interval with a non-platinum therapy in platinum-sensitive recurrent ovarian cancer
    • Pignata S., Ferrandina G., Scarfone G., Scollo P., Odicino F., Selvaggi L., et al. Extending the platinum-free interval with a non-platinum therapy in platinum-sensitive recurrent ovarian cancer. Oncology 2006, 71:320-326.
    • (2006) Oncology , vol.71 , pp. 320-326
    • Pignata, S.1    Ferrandina, G.2    Scarfone, G.3    Scollo, P.4    Odicino, F.5    Selvaggi, L.6
  • 36
    • 84891738037 scopus 로고    scopus 로고
    • MITO-8: ClinicalTrials.gov Identifier
    • NCT00657878 ClinicalTrials.gov website
    • MITO-8: ClinicalTrials.gov Identifier: NCT00657878 ClinicalTrials.gov website. http://clinicaltrials.gov/ct2/results?term=NCT00657878.
  • 38
    • 24944460785 scopus 로고    scopus 로고
    • Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study
    • Garcia-Carbonero R., Supko J.G., Maki R.G., Manola J., Ryan D.P., Harmon D., et al. Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study. Clin Oncol 2005, 23:5484-5492.
    • (2005) Clin Oncol , vol.23 , pp. 5484-5492
    • Garcia-Carbonero, R.1    Supko, J.G.2    Maki, R.G.3    Manola, J.4    Ryan, D.P.5    Harmon, D.6
  • 39
    • 35048860778 scopus 로고    scopus 로고
    • Trabectedin: a review of its use in the management of soft tissue sarcoma and ovarian cancer
    • Carter N.J., Keam S.J. Trabectedin: a review of its use in the management of soft tissue sarcoma and ovarian cancer. Drugs 2007, 67:2257-2276.
    • (2007) Drugs , vol.67 , pp. 2257-2276
    • Carter, N.J.1    Keam, S.J.2
  • 41
    • 72949084796 scopus 로고    scopus 로고
    • Trabectedin: an anticancer drug from the sea
    • Ganjoo K.N., Patel S.R. Trabectedin: an anticancer drug from the sea. Expert Opin Pharmacother 2009, 10:2735-2743.
    • (2009) Expert Opin Pharmacother , vol.10 , pp. 2735-2743
    • Ganjoo, K.N.1    Patel, S.R.2
  • 42
    • 20144377216 scopus 로고    scopus 로고
    • Trabectedin for women with ovarian carcinoma after treatment with platinum and taxanes fails
    • Sessa C., De Braud F., Perotti A., Bauer J., Curigliano G., Noberasco C., et al. Trabectedin for women with ovarian carcinoma after treatment with platinum and taxanes fails. J Clin Oncol 2005, 23:1867-1874.
    • (2005) J Clin Oncol , vol.23 , pp. 1867-1874
    • Sessa, C.1    De Braud, F.2    Perotti, A.3    Bauer, J.4    Curigliano, G.5    Noberasco, C.6
  • 43
    • 37049038819 scopus 로고    scopus 로고
    • A phase II study of trabectedin single agent in patients with recurrent ovarian cancer previously treated with platinum based regimens
    • Krasner C.N., McMeekin D.S., Chan S., Braly P.S., Renshaw F.G., Kaye S., et al. A phase II study of trabectedin single agent in patients with recurrent ovarian cancer previously treated with platinum based regimens. Br J Cancer 2007, 97:1618-1624.
    • (2007) Br J Cancer , vol.97 , pp. 1618-1624
    • Krasner, C.N.1    McMeekin, D.S.2    Chan, S.3    Braly, P.S.4    Renshaw, F.G.5    Kaye, S.6
  • 46
    • 79960073564 scopus 로고    scopus 로고
    • Efficacy of trabectedin in platinum-sensitive relapsed ovarian cancer-new data from the randomized OVA-301 Study
    • Colombo N. Efficacy of trabectedin in platinum-sensitive relapsed ovarian cancer-new data from the randomized OVA-301 Study. Int J Gynecol Cancer 2011, 21:S12-S16.
    • (2011) Int J Gynecol Cancer , vol.21
    • Colombo, N.1
  • 47
    • 78650325827 scopus 로고    scopus 로고
    • Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer: outcomes in the partially platinum-sensitive (platinum-free interval 6-12 months) subpopulation of OVA-301 phase III randomized trial
    • Poveda A., Vergote I., Tjulandin S., Kong B., Roy M., Chan S., et al. Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer: outcomes in the partially platinum-sensitive (platinum-free interval 6-12 months) subpopulation of OVA-301 phase III randomized trial. Ann Oncol 2011, 22:39-48.
    • (2011) Ann Oncol , vol.22 , pp. 39-48
    • Poveda, A.1    Vergote, I.2    Tjulandin, S.3    Kong, B.4    Roy, M.5    Chan, S.6
  • 48
    • 78650312260 scopus 로고    scopus 로고
    • Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer delays third-line chemotherapy and prolongs the platinum-free interval
    • Kaye S.B., Colombo N., Monk B.J., Tjulandin S., Kong B., Roy M., et al. Trabectedin plus pegylated liposomal doxorubicin in relapsed ovarian cancer delays third-line chemotherapy and prolongs the platinum-free interval. Ann Oncol 2011, 22:49-58.
    • (2011) Ann Oncol , vol.22 , pp. 49-58
    • Kaye, S.B.1    Colombo, N.2    Monk, B.J.3    Tjulandin, S.4    Kong, B.5    Roy, M.6
  • 49
    • 84891743745 scopus 로고    scopus 로고
    • INOVATYON STUDY: ClinicalTrials
    • NCT01379989. ClinicalTrials.gov website
    • INOVATYON STUDY: ClinicalTrials.gov Identifier: NCT01379989. ClinicalTrials.gov website. http://clinicaltrials.gov/ct2/results?term=NCT01379989.
    • Gov Identifier


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.