Identification of a macro-alkaline phosphatase complex in a patient with inflammatory bowel disease

Annals of Clinical Biochemistry

Volumn 49, Issue 4, 2012, Pages 405-407

  McTaggart, Malcolm P ^a   Rawson, Catherine ^a   Lawrence, David ^a   Raney, Barbara S ^a   Jaundrill, Linnet ^a   Miller, Lorna A ^a   Murtinho Braga, Joseph ^b   Kearney, Edward M ^a  

^a EAST KENT HOSPITALS UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^b Northdown Surgery   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; MACRO ALKALINE PHOSPHATASE; MACROGOL; MESALAZINE; UNCLASSIFIED DRUG;

ADULT; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CASE REPORT; CENTRIFUGATION; CLINICAL FEATURE; DEFECATION HABIT; DIARRHEA; ENZYME ACTIVITY; ENZYME ELECTROPHORESIS; HUMAN; HUMAN TISSUE; MALE; OCCULT BLOOD; PRECIPITATION; PRIORITY JOURNAL; RECTUM BIOPSY; SIGMOIDOSCOPY; TREATMENT OUTCOME; ULCERATIVE COLITIS;

ADULT; ALKALINE PHOSPHATASE; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE;

EID: 84867121873     PISSN: 00045632     EISSN: 17581001     Source Type: Journal    
DOI: 10.1258/acb.2011.011224     Document Type: Article

References (12)

1. Rhone DP, White FM, Gidaspow H. Isoenzymes of liver alkaline phosphatase in serum of patients with hepatobiliary disorders. Clin Chem 1973;19:1142-7
2. McLachlan R, Coakley J, Murton L, Campbell N. Plasma intestinal alkaline phosphatase isoenzymes in neonates with bowel necrosis. J Clin Pathol 1993;46:654-9
3. Tsumura M, Ueno Y, Kinouchi T, Koyama I, Komoda T. Atypical alkaline phosphatase isoenzymes in serum and urine of patients with renal failure. Clin Chim Acta 2001;312:169-78
4. Buttery JE, Milner CR, Nenadovic P, Pannall PR. Detection of alkaline phosphatase/immunoglobulin complexes. Clin Chem 1980;26:1620-1
5. Crofton PM, Kilpatrick DC, Leitch AG. Complexes in serum between alkaline phosphatase and immunoglobulin G: immunological and clinical aspects. Clin Chim Acta 1981;111:257-65
6. Wenham PR, Chapman B, Smith AF. Two macromolecular complexes between alkaline phosphatase and immunoglobulin A in a patient's serum. Clin Chem 1983;29:1845-9
7. Maekawa M, Sudo K, Kanno T. Characteristics of the complex between alkaline phosphatase and immunoglobulin A in human serum. Clin Chem Acta 1985;30:185-95
8. Owen MC, Pike LS, George PM, Barclay ML, Florkowski CM. Macro-alkaline phosphatase due to IgG k complex: demonstration with polyethylene glycol precipitation and immunofixation. Ann Clin Biochem 2002;39:523-5
9. Watanabe M, Kitahora T, Aiso S, et al. A case of ulcerative colitis associated with alkaline phosphatase (ALP)-and lactate dehydrogenase (LDH)-binding immunoglobulins. Nippon Shokakibyo Zasshi 1984;81:1468-73
10. Horie Y, Chiba M, Lizuka M, Watanabe H, Masamune O, Kakizaki Y. A case of ulcerative colitis with positive alkaline phosphatase-linked immunoglobulin. Nippon Shokakibyo Gakkai Zasshi 1989;86:1326-30
11. Carter MJ, Lobo AJ, Travis SPL. Guidelines for the management of inflammatory bowel disease in adults. Gut 2004;53(Suppl V):v1-v16
12. Davidson DF, Watson DJM. Macroenzyme detection by polyethylene glycol precipitation. Ann Clin Biochem 2003;40:514-20