QT interval prolongation by acute gastrointestinal bleeding in patients with cirrhosis

Liver International

Volumn 32, Issue 10, 2012, Pages 1510-1515

  Trevisani, Franco ^a   Di Micoli, Antonio ^a   Zambruni, Andrea ^b   Biselli, Maurizio ^a   Santi, Valentina ^a   Erroi, Virginia ^a   Lenzi, Barbara ^a   Caraceni, Paolo ^a   Domenicali, Marco ^a   Cavazza, Mario ^b   Bernardi, Mauro ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

6 week mortality; Acute gastrointestinal bleeding; Cirrhosis; Cirrhotic cardiomyopathy; MELD; Prognosis; QT interval

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DECISION MAKING; FEMALE; GASTROINTESTINAL HEMORRHAGE; HEART RATE; HIGH RISK PATIENT; HUMAN; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MODEL OF END STAGE LIVER DISEASE SCORE; MORTALITY; PROGNOSIS; QT PROLONGATION; RISK FACTOR; SCORING SYSTEM; SURVIVOR;

ANALYSIS OF VARIANCE; ELECTROCARDIOGRAPHY; GASTROINTESTINAL HEMORRHAGE; HEART RATE; HUMANS; LIVER CIRRHOSIS; LONG QT SYNDROME; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84867102018     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2012.02847.x     Document Type: Article

References (21)

1. Alqahtani SA, Fouad TR, Lee SS Cirrhotic cardiomyopathy. Semin Liver Dis 2008; 28: 59-69.
2. Zambruni A, Trevisani F, Caraceni P, Bernardi M Cardiac electrophysiological abnormalities in patients with cirrhosis. J Hepatol 2006; 44: 994-1002.
3. Bernardi M, Calandra S, Colantoni A, et al. Q-T interval prolongation in cirrhosis: prevalence, relationship with severity and etiology of the disease, and possible pathogenetic factors. Hepatology 1998; 27: 28-34.
4. + channels. Physiol Rev 2005; 85: 33-47.
5. Henriksen JH, Bendtsen F, Hansen EF, et al. Acute non-selective β-adrenergic blockade reduces prolonged frequency-adjusted Q-T interval in patients with cirrhosis. J Hepatol 2004; 40: 239-46.
6. Zambruni A, Trevisani F, Di Micoli A, et al. Effect of chronic beta-blockade on QT interval in patients with liver cirrhosis. J Hepatol 2008; 48: 415-21.
7. Jiménez-Candil J, Diego M, Cruz González I, et al. Relationship between the QTc interval at hospital admission and the severity of the underlying ischaemia in low and intermediate risk people studied for acute chest pain. Int J Cardiol 2008; 126: 84-91.
8. Day PC, James FWO, Butler JT, Campbell RWF Q-T prolongation and sudden cardiac death in patients with alcoholic liver disease. Lancet 1993; 341: 1423-8.
9. Ruiz-del-Arbol L, Monescillo A, Arocena C, et al. Circulatory function and hepatorenal syndrome in cirrhosis. Hepatology 2005; 42: 439-47.
10. Zambruni A, Di Micoli A, Lubisco A, et al. QT interval correction in patients with cirrhosis. J Cardiovasc Electrophysiol 2007; 18: 77-82.
11. Fridericia LS Die Systolendauer im Elekrokardiogramm bei normalen Menshenund bei Herzkranken. Acta Med Scand 1920; 53: 469-86.
12. Mangoni AA, Kinirons MT, Swift CG, Jackson SH Impact of age on QT interval and QT dispersion in healthy subjects: a regression analysis. Age Ageing 2003; 32: 326-31.
13. Hansen S, Møller S, Bendtsen F, et al. Diurnal variation and dispersion in QT interval in cirrhosis: relation to haemodynamic changes. J Hepatol 2007; 47: 373-80.
14. Henriksen J H, Gulberg V, Fuglsang S, et al. Q-T interval (QTc) in patients with cirrhosis. Relation to vasoactive peptides and heart rate. Scand J Clin Lab Invest 2007; 67: 643-53.
15. D'Amico G, De Franchis R; Cooperative Study Group. Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators. Hepatology 2003; 38: 599-612.
16. Roumen RM, Hendriks T, van der Ven-Jongekrijg J, et al. Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure. Ann Surg 1993; 218: 769-76.
17. Zingarelli B, Squadrito F, Altavilla D, et al. Evidence for a role of nitric oxide in hypovolemic hemorrhagic shock. J Cardiovasc Pharmacol 1992; 19: 982-6.
18. Bambha K, Kim WR, Pedersen R, et al. Predictors of early re-bleeding and mortality after acute variceal haemorrhage in patients with cirrhosis. Gut 2008; 57: 814-20.
19. Amitrano L, Guardascione MA, Bennato R, Manguso F, Balzano A MELD score and hepatocellular carcinoma identify patients at different risk of short-term mortality among cirrhotics bleeding from esophageal varices. J Hepatol 2005; 42: 820-5.
20. Chalasani N, Kahi C, Francois F, et al. Model for end-stage liver disease (MELD) for predicting mortality in patients with acute variceal bleeding. Hepatology 2002; 35: 1282-4.
21. Faigel DO, Metz DC, Kochman ML Torsade de pointes complicating the treatment of bleeding esophageal varices: association with neuroleptics, vasopressin and electrolyte imbalance. Am J Gastroenterol 1995; 90: 822-4.