Predictive factors for diabetic foot ulceration: A systematic review

Diabetes/Metabolism Research and Reviews

Volumn 28, Issue 7, 2012, Pages 574-600

  Monteiro Soares, M ^a,b   Boyko, E J ^c   Ribeiro, J ^b   Ribeiro, I ^d   Dinis Ribeiro, M ^b  

^a CENTRO HOSPITALAR DE VILA NOVA DE GAIA ESPINHO   (Portugal)

^b University of Porto   (Portugal)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Matosinhos Local Health Unity Atlântida Extension ^*  (Portugal)

Author keywords

Diabetic foot; Prediction; Risk variables; Systematic review

Indexed keywords

DIABETIC FOOT; DISEASE ASSOCIATION; EVALUATION; HUMAN; PREDICTION; PREDICTOR VARIABLE; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; STUDY DESIGN; SYSTEMATIC REVIEW;

DIABETIC FOOT; EVIDENCE-BASED MEDICINE; HUMANS; PREVALENCE; PROGNOSIS; RISK FACTORS;

EID: 84867077775     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.2319     Document Type: Review

References (85)

1. Boulton AJ, Vileikyte L, Ragnarson-Tennvall G, Apelqvist J. The global burden of diabetic foot disease. Lancet 2005; 366: 1719-1724.
2. Gonzalez JS, Vileikyte L, Ulbrecht JS, et al. Depression predicts first but not recurrent diabetic foot ulcers. Diabetologia 2010; 53: 2241-2248.
3. Ghanassia E, Villon L, Thuan dit Dieudonne J, Boegner C, Avignon A, Sultan A. Diabetic patients hospitalized for diabetic foot ulcers: a 6.5 years follow-up study. Diabetes Care 2008; 31: 1288-1292.
4. Boyko EJ, Ahroni JH, Smith DG, Davignon D. Increased mortality rate associated with diabetic foot ulcer. Diabet Med 1996; 13: 967-972.
5. Boulton AJ, Armstrong DG, Albert SF, et al. Comprehensive foot examination and risk assessment. Endocr Pract 2008; 14(5): 576-583.
6. Boyko EJ, Ahroni JH, Cohen V, et al. Prediction of diabetic foot ulcer occurrence using commonly available clinical information: the Seattle Diabetic Foot Study. Diabetes Care 2006; 29(6): 1202-1207.
7. Monteiro-Soares M, Boyko EJ, Ribeiro J, Ribeiro I, Dinis-Ribeiro M. Risk stratification systems for diabetic foot ulcers: a systematic review. Diabetologia 2011; 54(5): 1190-1199.
8. von Elm E, Altman DG, Egger M, et al. STROBE initiative. The Strengthening of the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. PLoS Med 2007; 4(10): e296.
9. Altman DG, Schulz KF, Moher D, et al. The Revised CONSORT Statement for Reporting Randomized Trials: explanation and elaboration. Ann Inter Med 2001; 134: 663-694.
10. Armstrong DG, Holtz-Neiderer K, Wendel C, Mohler MJ, Kimbriel HR, Lavery LA. Skin temperature monitoring reduces the risk for diabetic foot ulceration in high-risk patients. Am J Med 2007; 120: 1042-1046.
11. Lavery LA, Higgins KR, Lanctot DR, et al. Home monitoring of foot skin temperatures to prevent ulceration. Diabetes Care 2004; 27(11): 2642-2647.
12. Armstrong DG, Holtz K, Wu S. Can the use of a topical antifungal nail lacquer reduce risk for diabetic foot ulceration? Results from a randomized controlled pilot study. Int Wound J 2005; 2: 166-170.
13. Boyko EJ, Ahroni JH, Stensel V, et al. A prospective study of risk factors for diabetic foot ulcer. The Seattle Diabetic Foot Study. Diabetes Care 1999; 22(7): 1036-1042.
14. Abbott CA, Carrington AL, Ashe H, et al. The North-West Diabetes Foot Care study: incidence of, and risk factors for, new diabetic foot ulceration in a community-based patient cohort. Diabet Med 2002; 19(5): 377-384.
15. Williams LH, Rutter CM, Katon WJ, et al. Depression and incident diabetic foot ulcers: a prospective cohort study. Am J Med 2010; 123: 748-754.
16. Monteiro-Soares M, Dinis-Ribeiro M. External validation and optimisation of a model predicting foot ulcers in patients with diabetes. Diabetologia 2010; 53: 1525-1533.
17. Kästenbauer T, Sauseng S, Sokol G, Auinger M, Irsigler K. A prospective study of predictors for foot ulceration in type 2 diabetes. J Am Podriatr Med Assoc 2001; 91(7): 343-350.
18. Ledoux WR, Shofer JB, Smith DG, et al. Relationship between foot type, foot deformity, and ulcer occurrence in the high-risk diabetic foot. J Rehab Res & Dev 2005; 42(5): 665-672.
19. Suico JG, Marriott DJ, Vinicor F, Litzelman DK. Behaviors predicting foot lesions in patients with non-insulin-dependent diabetes mellitus. J Gen Int Med 1998; 13(7): 482-484.
20. Pham H, Armstrong DG, Harvey C, et al. Screening techniques to identify people at high risk for diabetic foot ulceration. Diabetes Care 2000; 23: 606-611.
21. Armstrong DG, Lavery LA, Holtz-Neiderer K, et al. Variability in activity may precede diabetic foot ulceration. Diabetes Care 2004; 27: 1980-1984.
22. Abbott CA, Vileikyte L, Williamson S, Carrington AL, Boulton AJ. Multicenter study of the incidence of and predictive risk factors for diabetic neuropathic ulceration. Diabetes Care 1998; 21(7): 1071-1075.
23. Lavery LA, Armstrong DG, Wunderlich RP, Tredwell J, Boulton AJ. Predictive value of foot pressure assessment as part of a population-based diabetes disease management program. Diabetes Care 2003; 26(4): 1069-1073.
24. Caselli A, Pham H, Giurini JM, Armstrong DG, Veves A. The forefoot-to-rearfoot plantar pressure ratio is increased in severe diabetic neuropathy and can predict foot ulceration. Diabetes Care 2002; 25(6): 1066-1071.
25. Monami M, Vivarelli M, Desideri CM, et al. Pulse pressure and prediction of incident foot ulcers in type 2 diabetes. Diabetes Care 2009; 32: 897-899.
26. Armstrong DG, Lavery LA, Wunderlich RP, Boulton AJ. Skin temperature as a one-time screening tool do not predict future diabetic foot complications. J Am Podiatr Med Assoc 2003; 93(6): 443-447.
27. Murray HJ, Young MJ, Hollis S, Boulton AJ. The association between callus formation, high pressures and neuropathy in diabetic foot ulceration. Diabet Med 1996; 13: 979-982.
28. Chantelau E, Kushner T, Spraul M. How effective is cushioned therapeutic footwear in protecting diabetic feet? A clinical study. Diabet Med 1990; 7: 355-359.
29. Margolis DJ, Hofstad O, Feldman HI. Association between renal failure and foot ulcer or lower extremity amputation in patients with diabetes. Diabetes Care 2008; 31(7): 1331-1336.
30. Carrington AL, Shaw JE, Van Schie CH, et al. Can motor nerve conduction velocity predict foot problems in diabetic subjects over a 6-year outcome period? Diabetes Care 2002; 25(11): 2010-2015.
31. Calle-Pascual AL, Durán A, Benedí A, et al. Reduction in foot ulcer incidence: relation to compliance with a prophylactic foot care program. Diabetes Care 2001; 24(2): 405-407.
32. McGill M, Molyneaux L, Yue DK. Which diabetic patients should receive podiatry care? An objective analysis. Inter Med J 2005; 35: 451-456.
33. Lincoln NB, Radford KA, Game FL, Jeffcoate WJ. Education for secondary prevention of foot ulcers in people with diabetes: a randomised controlled trial. Diabetologia 2008; 51(11): 1954-1961.
34. Lavery LA, Higgins KR, Lanctot DR, et al. Preventing diabetic foot ulcer recurrence in high-risk patients. Diabetes Care 2007; 30: 14-20.
35. Reiber GE, Smith DG, Wallace C, et al. Effect of therapeutic footwear on foot reulceration in patients with diabetes: a randomized controlled trial. JAMA 2002; 287: 2552-2558.
36. Plank J, Haas W, Rakovac I, et al. Evaluation of the impact of chiropodist care in the secondary prevention of foot ulcerations in diabetic subjects. Diabetes Care 2003; 26(6): 1691-1695.
37. Uccioli L, Faglia E, Monticone G, et al. Manufactured shoes in the prevention of diabetic foot ulcers. Diabetes Care 1995; 10: 1376-1378.
38. Lemaster JW, Reiber GE, Smith DG, Heagerty PJ, Wallace C. Daily weight-bearing activity does not increase the risk of diabetic foot ulcers. Med Sci Sports Exerc 2003; 35(7): 1093-1099.
39. Dargis V, Pantelejeva O, Jonushaite A, Vileikyte L, Boulton AJ. Benefits of a multidisciplinary approach in the management of recurrent diabetic foot ulceration in Lithuania. Diabetes Care 1999; 22: 1428-1431.
40. Kloos C, Hagen F, Lindloh C, Braun A, et al. Cognitive function is not associated with recurrent foot ulcers in patients with diabetes and neuropathy. Diabetes Care 2010; 32: 894-896.
41. Busch K, Chantelau E. Effectiveness of a new brand of stock "diabetic" shoes to protect against diabetic foot ulcer relapse: a prospective cohort study. Diabet Med 2003; 20: 665-669.
42. Faglia E, Favales F, Morabito A. New ulceration, new major amputation, and survival rates in diabetic subjects hospitalized for foot ulceration from 1990 to 1993. Diabetes Care 2001; 24: 78-83.
43. Peters EJ, Armstrong DG, Lavery LA. Risk factors for recurrent diabetic foot ulcers. Diabetes Care 2007; 30(8): 2077-2079.
44. Diouri A, Slaoui Z, Chadli A, et al. Étude de la fréquence et des facteurs favorisant les récidives des ulcères de pied chez les patients diabétiques. Ann Endocrinol 2002; 63(6): 491-496.
45. Chantelau E, Haage P. An audit of cushioned diabetic footwear: relation to patient compliance. Diabet Med 1994; 11: 114-116.
46. Litzelman DK, Marriott DJ, Vinicor F. The role of footwear in the prevention of foot lesions in patients with NIDDM. Conventional wisdom or evidence-based practice? Diabetes Care 1997a; 20(2): 156-162.
47. Litzelman DK, Marriott DJ, Vinicor F. Independent physiological predictors of foot lesions in patients with NIDDM. Diabetes Care 1997b; 20(8): 1273-1278.
48. Olmos PR, Cataland S, O'Dorisio TM, et al. The Semmes-Weinstein monofilament as a potential predictor of foot ulceration in patients with noninsulin-dependent diabetes. Am J Med Sci 1995; 309(2): 76-82.
49. Sriussadaporn S, Mekanandha P, Vannasaeng S, et al. Factors associated with diabetic foot ulceration in Thailand: a case-control study. Diabet Med 1997; 14(1): 50-56.
50. Armstrong DG, Peters EJ, Athanasiou KA, Lavery LA. Is there a critical level of plantar foot pressure to identify patients at risk for neuropathic foot ulceration? J Foot Ankle Surg 1998a; 37(4): 303-307.
51. Lavery LA, Armsrong DG, Vela SA, Quebedeaux TL, Fleischli JG. Practical criteria for screening patients at high risk for diabetic foot ulceration. Arch Intern Med 1998; 158: 157-162.
52. Armstrong DG, Lavery LA, Vela SA, Quebedeaux TL, Fleischli JG. Choosing a practical screening instrument to identify patients at risk for diabetic foot ulceration. Arch Inter Med 1998b; 158: 289-292.
53. Sauseng S, Kästenbauer T, Sokol G, Irsigler K. Estimation of risk for plantar foot ulceration in diabetic patients with neuropathy. Diab Nutr Metab 1999; 12: 189-193.
54. Ndip A, Rutter M, Vileikyte L, et al. Dialysis treatment is an independent risk factor for foot ulceration in patients with diabetes and stage 4 and 5 chronic kidney disease. Diabetes Care 2010; 33: 1811-1816.
55. Ndip A, Lavery LA, LaFontaine J, et al. High levels of foot ulceration and amputation risk in a multirracial cohort of diabetic patients on dialysis therapy. Diabetes Care 2010; 33: 878-880.
56. Porciúncula MV, Rolim LC, Garofolo L, Ferreira SR. Análise de fatores associados à ulceração de extremidades em indivíduos diabéticos com neuropatia periférica. Arq Bras Endocrinol Metab 2007; 51(7): 1134-1142.
57. González R, Pedro T, Real JT, et al. Plasma homocysteine levels are associated with ulceration of the foot in patients with type 2 diabetes mellitus. Diabetes Metab Res Rev 2010; 26: 115-120.
58. Armstrong DG, Lavery LA, Liswood PJ, Todd WF, Tredwell JA. Infrared dermal thermometry for the high-risk diabetic foot. Phys Ther 1997; 77(2): 169-177.
59. Tentolouris N, Voulgari C, Liatis S, et al. Moisture status of the skin of the feet assessed by the visual test neuropad correlates with foot ulceration in diabetes. Diabetes Care 2010; 33: 1112-1114.
60. Tentolouris N, Marinou K, Kokotis P, Karanti A, Diakoumopoulou E, Katsilambros N. Sudomotor dysfunction is associated with foot ulceration in diabetes. Diabet Med 2009; 26: 302-305.
61. Frykberg RG, Lavery LA, Pham H, et al. Role of neuropathy and high foot pressures in diabetic foot ulceration. Diabetes Care 1998; 21: 1714-1719.
62. Bresäter LE, Welin L, Romanus B. Foot pathology and risk factors for diabetic foot disease in elderly men. Diab Res & Clin Pract 1996; 32: 103-109.
63. de Sonnaville JJ, Colly LP, Wijkel D, Heine RJ. The prevalence and determinants of foot ulceration in type II diabetic patients in a primary health care setting. Diab Res & Clin Pract 1997; 35: 149-156.
64. Jirkovská A, Boucek P, Wosková V, Bartos V, Skibová J, et al. Identification of patients at risk for diabetic foot: a comparison of standardized noninvasive testing with routine practice at community diabetes clinics. J Diab Compl 2001; 15: 63-68.
65. Guerrero-Romero F, Rodríguez-Morán M. Relationship of microalbuminuria with the diabetic foot ulcers in type II diabetes. J Diab Compl 1998; 12(4): 193-196.
66. Abbott CA, Garrott AP, Carrington AL, et al. Foot ulcer risk is lower in South-Asian and African-Caribbean compared with European diabetic patients in the UK. Diabetes Care 2005; 28: 1869-1875.
67. Miranda-Palma B, Sosenko JM, Bowker JH, Mizel MS, Boulton AJ. A comparison of the monofilament with other testing modalities for foot ulcer susceptibility. Diab Res Clin Pract 2005; 70: 8-12.
68. Saltzman CL, Rashid R, Hayes A, et al. 4.5-gram monofilament sensation beneath both first metatarsal heads indicates protective foot sensation in diabetic patients. J Bone & Joint Surg 2004; 86(4): 717-723.
69. Bennett PJ, Stocks AE, Whittam DJ. Analysis of risk factors for neuropathic foot ulceration in diabetes mellitus. J Am Podiatr Med Assoc 1996; 86(3): 112-116.
70. McNeely MJ, Boyko EJ, Ahroni JH, et al. The independent contributions of diabetic neuropathy and vasculopathy in foot ulceration: how great are the risks? Diabetes Care 1995; 18(2): 216-219.
71. Gulliford MC, Mahabir D. Diabetic foot disease and foot care in a Caribbean community. Diab Res Clin Pract 2002; 56: 35-40.
72. Boulton AJ, Kubrusly DB, Bowker JH, et al. Impaired vibratory perception and diabetic foot ulceration. Diabet Med 1986; 3: 335-337.
73. Iversen MM, Mifdtjell K, Ostbye T, et al. History of and factors associated with diabetic foot ulcers in Norway: the Nord-Trondelag Health Study. Scand J Public Health 2008; 36(1): 62-68.
74. Control Disease Center (CDC). History of foot ulcer among persons with diabetes - United States 2000-2002. MMWR 2003; 52(45): 1098-1102.
75. Lott DJ, Zou D, Mueller MJ. Pressure gradient and subsurface shear stress on the neuropathic forefoot. Clin Biomech 2008; 23: 342-348.
76. Jayasinghe SA, Atukorala I, Gunethilleke B, et al. Is walking barefoot a risk factor for diabetic foot disease in developing countries? Rural Remote Health 2007; 7: 692-698.
77. Maluf KS, Mueller MJ. Comparison of physical activity and cumulative plantar tissue stress among subjects with and without diabetes mellitus and a history of recurrent plantar ulcers. Clin Biomech 2003; 18: 567-575.
78. Papanas N, Gries A, Maltezos E, Zick R. The steel ball-bearing test: a new test for evaluating protective sensation in the diabetic foot. Diabetologia 2006; 49: 739-743.
79. Boulton AJ, Meneses P, Ennis WJ. Diabetic foot ulcers: a framework for prevention and care. Wound Rep Reg 1999; 7: 7-16.
80. Morbach S. Diagnosis, Treatment and Prevention of the Diabetic Foot Syndrome. Paul Hartmann AG: Germany, 2003. ISBN 3-929870-29-0.
81. Callaghan BC, Feldman E, Liu J, Kerber K, Pop-Busui R, Moffet H, Karter AJ. Triglycerides and amputation risk in patients with diabetes: ten-year follow-up in the DISTANCE study. Diabetes Care 2011; 34(3): 635-640.
82. Rajamani K, Colman PG, Li LP, Best JD, et al. Effect of fenofibrate on amputation events in people with type 2 diabetes mellitus (FIELD study): a prespecified analysis of a randomised controlled trial. Lancet 2009; 373(9677): 1780-1788.
83. Dros J, Wewerinke A, Bindels PK, van Weert HC. Accuracy of monofilament testing to diagnose peripheral neuropathy: a systematic review. Ann Fam Med 2009; 7(6): 555-558.
84. Feng Y, Schlösser FJ, Sumpio BE. The Semmes Weinstein monofilament examination as a screening tool for diabetic peripheral neuropathy. J Vasc Surg 2009; 50(3): 675-682.
85. Crawford F, Inkster M, Kleijnen J, Fahey T. Predicting foot ulcers in patients with diabetes: a systematic review and meta-analysis. Q J Med 2007; 100: 65-68.