Genetic testing in brugada syndrome

Journal of the American College of Cardiology

Volumn 60, Issue 15, 2012, Pages 1419-1420

  Kaufman, Elizabeth S ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Brugada syndrome; cardiac arrest; genetic testing; ST segment elevation; ventricular arrhythmias

Indexed keywords

AGE DISTRIBUTION; ALLELE; BRS1 GENE; BRS12 GENE; BRUGADA SYNDROME; GENE; GENE MUTATION; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; NOTE; PREVALENCE; PRIORITY JOURNAL; QT INTERVAL; SCN5A GENE; SEX DIFFERENCE;

EID: 84867066965     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2012.05.011     Document Type: Editorial

References (11)

1. P. Brugada, J. Brugada Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome A multicenter report J Am Coll Cardiol 20 1992 1391 1396
2. I. Gussak, C. Antzelevitch, P. Bjerregaard, J.A. Towbin, B.R. Chaitman The Brugada syndrome: clinical, electrophysiologic and genetic aspects J Am Coll Cardiol 33 1999 5 15
3. C. Antzelevitch Brugada syndrome Pacing Clin Electrophysiol 29 2006 1130 1159
4. C. Antzelevitch, P. Brugada, M. Borggrefe Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association Circulation 111 2005 659 670
5. S.G. Priori, C. Napolitano, M. Gasparini Natural history of Brugada syndrome - insights for risk stratification and management Circulation 105 2002 1342 1347
6. E. Schulze-Bahr, L. Eckardt, G. Breithardt Sodium channel gene (SCN5A) mutations in 44 index patients with Brugada syndrome: different incidences in familial and sporadic disease Hum Mutat 21 2003 651 652
7. S.G. Priori, C. Napolitano, M. Gasparini Clinical and genetic heterogeneity of right bundle branch block and ST-segment elevation syndrome: a prospective evaluation of 52 families Circulation 21 2000 651 652
8. L. Crotti, C.A. Marcou, D.J. Tester Spectrum and prevalence of mutations involving BrS1- through BrS12-susceptibility genes in a cohort of unrelated patients referred for Brugada syndrome genetic testing: implications for genetic testing J Am Coll Cardiol 60 2012 1410 1418
9. M.H. Gollob, L. Blier, R. Brugada Recommendations for the use of genetic testing in the clinical evaluation of inherited cardiac arrhythmias associated with sudden cardiac death: Canadian Cardiovascular Society/Canadian Heart Rhythm Society joint position paper Can J Cardiol 27 2011 232 245
10. M.J. Ackerman, S.G. Priori, S. Willems HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA) Heart Rhythm 8 2011 1308 1339
11. C. Antzelevitch, G.D. Pollevick, J.M. Cordeiro Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death Circulation 115 2007 442 449