-
1
-
-
0032984793
-
Tetraethylammonium block of the BNC1 channel
-
Adams CM, Price MP, Snyder PM, Welsh MJ. Tetraethylammonium block of the BNC1 channel. Biophys J 76: 1377-1383, 1999.
-
(1999)
Biophys J
, vol.76
, pp. 1377-1383
-
-
Adams, C.M.1
Price, M.P.2
Snyder, P.M.3
Welsh, M.J.4
-
2
-
-
0032515176
-
+ channel 1 by inducing a conformational change that exposes a residue associated with neurodegeneration
-
+ channel 1 by inducing a conformational change that exposes a residue associated with neurodegeneration. J Biol Chem 273: 30204-30207, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 30204-30207
-
-
Adams, C.M.1
Snyder, P.M.2
Price, M.P.3
Welsh, M.J.4
-
3
-
-
0032986088
-
Paradoxical stimulation of a DEG/ENaC channel by amiloride
-
Adams CM, Snyder PM, Welsh MJ. Paradoxical stimulation of a DEG/ENaC channel by amiloride. J Biol Chem 274: 15500-15504, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 15500-15504
-
-
Adams, C.M.1
Snyder, P.M.2
Welsh, M.J.3
-
4
-
-
0034647808
-
A new member of the acid-sensing ion channel family
-
Akopian AN, Chen CC, Ding Y, Cesare P, Wood JN. A new member of the acid-sensing ion channel family. Neuroreport 11: 2217-2222, 2000.
-
(2000)
Neuroreport
, vol.11
, pp. 2217-2222
-
-
Akopian, A.N.1
Chen, C.C.2
Ding, Y.3
Cesare, P.4
Wood, J.N.5
-
5
-
-
23444434692
-
Acid sensing ionic channels: Modulation by redox reagents
-
Andrey F, Tsintsadze T, Volkova T, Lozovaya N, Krishtal O. Acid sensing ionic channels: modulation by redox reagents. Biochim Biophys Ada 1745: 1-6, 2005.
-
(2005)
Biochim Biophys Ada
, vol.1745
, pp. 1-6
-
-
Andrey, F.1
Tsintsadze, T.2
Volkova, T.3
Lozovaya, N.4
Krishtal, O.5
-
6
-
-
0035932944
-
DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature
-
Askwith CC, Benson CJ, Welsh MJ, Snyder PM. DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature. Proc NatlAcad Sci USA 98: 6459-6463, 2001.
-
(2001)
Proc NatlAcad Sci USA
, vol.98
, pp. 6459-6463
-
-
Askwith, C.C.1
Benson, C.J.2
Welsh, M.J.3
Snyder, P.M.4
-
7
-
-
0033695107
-
Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels
-
Askwith CC, Cheng C, Ikuma M, Benson C, Price MP, Welsh MJ. Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels. Neuron 26: 133-141, 2000.
-
(2000)
Neuron
, vol.26
, pp. 133-141
-
-
Askwith, C.C.1
Cheng, C.2
Ikuma, M.3
Benson, C.4
Price, M.P.5
Welsh, M.J.6
-
9
-
-
0036828828
-
Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1)
-
Babini E, Paukert M, Geisler HS, Grander S. Alternative splicing and interaction with di- and polyvalent cations control the dynamic range of acid-sensing ion channel 1 (ASIC1). J Biol Chem 111: 41597-41603, 2002.
-
(2002)
J Biol Chem
, vol.111
, pp. 41597-41603
-
-
Babini, E.1
Paukert, M.2
Geisler, H.S.3
Grander, S.4
-
11
-
-
0032900533
-
Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties
-
Babinski K, Le KT, Seguela P. Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties. J Neurochem 72: 51-57, 1999.
-
(1999)
J Neurochem
, vol.72
, pp. 51-57
-
-
Babinski, K.1
Le, K.T.2
Seguela, P.3
-
12
-
-
77951523610
-
The contact region between three domains of the extracellular loop of ASICla is critical for channel function
-
Bargeton B, Kellenberger S. The contact region between three domains of the extracellular loop of ASICla is critical for channel function. J Biol Chem 285: 13816-13826, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 13816-13826
-
-
Bargeton, B.1
Kellenberger, S.2
-
14
-
-
60849122232
-
Two PKC consensus sites on human acid-sensing ion channel lb differentially regulate its function
-
Bashari E, Qadri YJ, Zhou ZH, Kapoor N, Anderson SJ, Meltzer RH, Fuller CM, Benos DJ. Two PKC consensus sites on human acid-sensing ion channel lb differentially regulate its function. Am J Physiol Cell Physiol 296: C372-C384, 2009.
-
(2009)
Am J Physiol Cell Physiol
, vol.296
-
-
Bashari, E.1
Qadri, Y.J.2
Zhou, Z.H.3
Kapoor, N.4
Anderson, S.J.5
Meltzer, R.H.6
Fuller, C.M.7
Benos, D.J.8
-
16
-
-
0035823511
-
Molecular and functional characterization of acid-sensing ion channel (ASIC) lb
-
Bassler EL, Ngo-Anh TJ, Geisler HS, Ruppersberg JP, Grunder S. Molecular and functional characterization of acid-sensing ion channel (ASIC) lb. J Biol Chem 276: 33782-33787, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 33782-33787
-
-
Bassler, E.L.1
Ngo-Anh, T.J.2
Geisler, H.S.3
Ruppersberg, J.P.4
Grunder, S.5
-
17
-
-
0033231432
-
Functional domains within the degenerin/ epithelial sodium channel (Deg/ENaC) superfamily of ion channels
-
Benos DJ, Stanton BA. Functional domains within the degenerin/ epithelial sodium channel (Deg/ENaC) superfamily of ion channels. J Physiol 520: 631-644, 1999.
-
(1999)
J Physiol
, vol.520
, pp. 631-644
-
-
Benos, D.J.1
Stanton, B.A.2
-
18
-
-
0037133199
-
+-gated channels in mouse sensory neurons
-
+-gated channels in mouse sensory neurons. Proc Natl Acad Sci USA 99: 2338-2343, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2338-2343
-
-
Benson, C.J.1
Xie, J.2
Wemmie, J.A.3
Price, M.P.4
Henss, J.M.5
Welsh, M.J.6
Snyder, P.M.7
-
19
-
-
0035914378
-
+ ion channel, in planar lipid bilayers
-
+ ion channel, in planar lipid bilayers. J Biol Chem 276: 38755-38761, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 38755-38761
-
-
Berdiev, B.K.1
Mapstone, T.B.2
Markert, J.M.3
Gillespie, G.Y.4
Lockhart, J.5
Fuller, C.M.6
Benos, D.J.7
-
20
-
-
81555227923
-
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
-
410-411
-
Bohlen CJ, Chesler AT, Sharif-Naeini R, Medzihradszky KF, Zhou S, King D, Sanchez EE, Burlingame AL, Basbaum AI, Julius D. A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain. Nature 479: 410-114, 2011.
-
(2011)
Nature
, vol.479
-
-
Bohlen, C.J.1
Chesler, A.T.2
Sharif-Naeini, R.3
Medzihradszky, K.F.4
Zhou, S.5
King, D.6
Sanchez, E.E.7
Burlingame, A.L.8
Basbaum, A.I.9
Julius, D.10
-
21
-
-
0034813981
-
Selective modulation of heteromeric ASIC proton-gated channels by neuropeptide FF
-
Catarsi S, Babinski K, Seguela P. Selective modulation of heteromeric ASIC proton-gated channels by neuropeptide FF. Neuropharmacology 41: 592-600, 2001.
-
(2001)
Neuropharmacology
, vol.41
, pp. 592-600
-
-
Catarsi, S.1
Babinski, K.2
Seguela, P.3
-
22
-
-
0025328345
-
The identification and suppression of inherited neurodegeneration in Caenorhabditis elegans
-
Chalfie M, Wolinsky E. The identification and suppression of inherited neurodegeneration in Caenorhabditis elegans. Nature 345: 410-416, 1990.
-
(1990)
Nature
, vol.345
, pp. 410-416
-
-
Chalfie, M.1
Wolinsky, E.2
-
24
-
-
0032544025
-
A sensory neuron-specific, proton-gated ion channel
-
Chen CC, England S, Akopian AN, Wood JN. A sensory neuron-specific, proton-gated ion channel. Proc Natl Acad Sci USA 95: 10240-10245, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 10240-10245
-
-
Chen, C.C.1
England, S.2
Akopian, A.N.3
Wood, J.N.4
-
25
-
-
0037173123
-
A role for ASIC3 in the modulation of high-intensity pain stimuli
-
Chen CC, Zimmer A, Sun WH, Hall J, Brownstein MJ. A role for ASIC3 in the modulation of high-intensity pain stimuli. Proc Natl Acad Sci USA 99: 8992-8997, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8992-8997
-
-
Chen, C.C.1
Zimmer, A.2
Sun, W.H.3
Hall, J.4
Brownstein, M.J.5
-
26
-
-
65249129029
-
Acid-sensing ion channels in neurones of the rat suprachiasmatic nucleus
-
Chen CH, Hsu YT, Chen CC, Huang RC. Acid-sensing ion channels in neurones of the rat suprachiasmatic nucleus. J Physiol 587: 1727-1737, 2009.
-
(2009)
J Physiol
, vol.587
, pp. 1727-1737
-
-
Chen, C.H.1
Hsu, Y.T.2
Chen, C.C.3
Huang, R.C.4
-
27
-
-
33947104112
-
Permeating protons contribute to tachyphylaxis of the acid-sensing ion channel (ASIC) la
-
Chen X, Grunder S. Permeating protons contribute to tachyphylaxis of the acid-sensing ion channel (ASIC) la. J Physiol 579: 657-670, 2007.
-
(2007)
J Physiol
, vol.579
, pp. 657-670
-
-
Chen, X.1
Grunder, S.2
-
28
-
-
33644596215
-
Interaction of acid-sensing ion channel (ASIC) 1 with the tarantula toxin psalmotoxin 1 is state dependent
-
Chen X, Kalbacher H, Grunder S. Interaction of acid-sensing ion channel (ASIC) 1 with the tarantula toxin psalmotoxin 1 is state dependent. J Gen Physiol 127: 267-276, 2006.
-
(2006)
J Gen Physiol
, vol.127
, pp. 267-276
-
-
Chen, X.1
Kalbacher, H.2
Grunder, S.3
-
29
-
-
22244439888
-
The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) la by increasing its apparent H+ affinity
-
Chen X, Kalbacher H, Grunder S. The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) la by increasing its apparent H+ affinity. J Gen Physiol 126: 71-79, 2005.
-
(2005)
J Gen Physiol
, vol.126
, pp. 71-79
-
-
Chen, X.1
Kalbacher, H.2
Grunder, S.3
-
30
-
-
33646922620
-
Strong modulation by RFamide neuropeptides of the ASIClb/3 heteromer in competition with extracellular calcium
-
Chen X, Paukert M, Kadurin I, Pusch M, Grunder S. Strong modulation by RFamide neuropeptides of the ASIClb/3 heteromer in competition with extracellular calcium. Neuropharmacology 50: 964-974. 2006.
-
(2006)
Neuropharmacology
, vol.50
, pp. 964-974
-
-
Chen, X.1
Paukert, M.2
Kadurin, I.3
Pusch, M.4
Grunder, S.5
-
31
-
-
0026705552
-
Modulation of pH by neuronal activity
-
Chesler M, Kaila K. Modulation of pH by neuronal activity. Trends Neurosci 15: 396-402, 1992.
-
(1992)
Trends Neurosci
, vol.15
, pp. 396-402
-
-
Chesler, M.1
Kaila, K.2
-
32
-
-
34447507908
-
Potentiation of acid-sensing ion channels by sulfhydryl compounds
-
Cho JH, Askwith C. Potentiation of acid-sensing ion channels by sulfhydryl compounds. Am J Physiol Cell Physiol 292: C2161-C2174. 2007.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Cho, J.H.1
Askwith, C.2
-
33
-
-
33744981629
-
ASICla-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents
-
Chu XP, Close N, Saugstad JA, Xiong ZG. ASICla-specific modulation of acid-sensing ion channels in mouse cortical neurons by redox reagents. J Neurosci 26: 5329-5339, 2006.
-
(2006)
J Neurosci
, vol.26
, pp. 5329-5339
-
-
Chu, X.P.1
Close, N.2
Saugstad, J.A.3
Xiong, Z.G.4
-
34
-
-
83455219290
-
Modulation of acid-sensing ion channels: Molecular mechanisms and therapeutic potential
-
Chu XP, Papasian CJ, Wang JQ, Xiong ZG. Modulation of acid-sensing ion channels: molecular mechanisms and therapeutic potential. Int J Physiol Pathophysiol Pharmacol 3: 288-309, 2011.
-
(2011)
Int J Physiol Pathophysiol Pharmacol
, vol.3
, pp. 288-309
-
-
Chu, X.P.1
Papasian, C.J.2
Wang, J.Q.3
Xiong, Z.G.4
-
35
-
-
5444232528
-
Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels
-
Chu XP, Wemmie JA, Wang WZ, Zhu XM, Saugstad JA, Price MP, Simon RP, Xiong ZG. Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels. J Neurosci 24: 8678-8689, 2004.
-
(2004)
J Neurosci
, vol.24
, pp. 8678-8689
-
-
Chu, X.P.1
Wemmie, J.A.2
Wang, W.Z.3
Zhu, X.M.4
Saugstad, J.A.5
Price, M.P.6
Simon, R.P.7
Xiong, Z.G.8
-
36
-
-
77951493120
-
Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cells
-
Chung WS, Farley JM, Swenson A, Barnard JM, Hamilton G, Chiposi R, Drummond HA. Extracellular acidosis activates ASIC-like channels in freshly isolated cerebral artery smooth muscle cells. Am J Physiol Cell Physiol 298: C1198-C1208, 2010.
-
(2010)
Am J Physiol Cell Physiol
, vol.298
-
-
Chung, W.S.1
Farley, J.M.2
Swenson, A.3
Barnard, J.M.4
Hamilton, G.5
Chiposi, R.6
Drummond, H.A.7
-
37
-
-
77956255078
-
Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptase
-
Clark EB, Jovov B, Rooj AK, Fuller CM, Benos DJ. Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptase. J Biol Chem 285: 27130-27143, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 27130-27143
-
-
Clark, E.B.1
Jovov, B.2
Rooj, A.K.3
Fuller, C.M.4
Benos, D.J.5
-
38
-
-
0242496525
-
The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1
-
Cork T, Zhang P, Todorovic N, Canessa CM. The extracellular domain determines the kinetics of desensitization in acid-sensitive ion channel 1. J Biol Chem 278: 45240-45247, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 45240-45247
-
-
Cork, T.1
Zhang, P.2
Todorovic, N.3
Canessa, C.M.4
-
39
-
-
27844521392
-
Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel
-
Cork T, Zheng D, Gerstein M, Canessa CM. Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel. J Physiol 568: 725-735, 2005.
-
(2005)
J Physiol
, vol.568
, pp. 725-735
-
-
Cork, T.1
Zheng, D.2
Gerstein, M.3
Canessa, C.M.4
-
40
-
-
65649108552
-
Acid-sensing ion channel-la in the amygdala, a novel therapeutic target in depression-related behavior
-
Coryell MW, Wunsch AM, Haenfler JM, Allen JE, Schnizler M, Ziemann AE, Cook MN, Dunning JP, Price MP, Rainier JD, Liu Z, Light AR, Langbehn DR, Wemmie JA. Acid-sensing ion channel-la in the amygdala, a novel therapeutic target in depression-related behavior. J Neurosci 29: 5381-5388, 2009.
-
(2009)
J Neurosci
, vol.29
, pp. 5381-5388
-
-
Coryell, M.W.1
Wunsch, A.M.2
Haenfler, J.M.3
Allen, J.E.4
Schnizler, M.5
Ziemann, A.E.6
Cook, M.N.7
Dunning, J.P.8
Price, M.P.9
Rainier, J.D.10
Liu, Z.11
Light, A.R.12
Langbehn, D.R.13
Wemmie, J.A.14
-
41
-
-
35648992042
-
Targeting ASIC la reduces innate fear and alters neuronal activity in the fear circuit
-
Coryell MW, Ziemann AE, Westmoreland PJ, Haenfler JM, Kurja-kovic Z, Zha XM, Price M, Schnizler MK, Wemmie JA. Targeting ASIC la reduces innate fear and alters neuronal activity in the fear circuit. Biol Psychiatry 62: 1140-1148, 2007.
-
(2007)
Biol Psychiatry
, vol.62
, pp. 1140-1148
-
-
Coryell, M.W.1
Ziemann, A.E.2
Westmoreland, P.J.3
Haenfler, J.M.4
Kurja-Kovic, Z.5
Zha, X.M.6
Price, M.7
Schnizler, M.K.8
Wemmie, J.A.9
-
42
-
-
0033537829
-
The pre-transmembrane 1 domain of acid-sensing ion channels participates in the ion pore
-
Coscoy S, de Weille JR, Lingueglia E, Lazdunski M. The pre-transmembrane 1 domain of acid-sensing ion channels participates in the ion pore. J Biol Chem 274: 10129-10132, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 10129-10132
-
-
Coscoy, S.1
de Weille, J.R.2
Lingueglia, E.3
Lazdunski, M.4
-
43
-
-
33947715893
-
A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3
-
Cushman KA, Marsh-Haffner J, Adelman JP, McCleskey EW. A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3. J Gen Physiol 129: 345-350, 2007.
-
(2007)
J Gen Physiol
, vol.129
, pp. 345-350
-
-
Cushman, K.A.1
Marsh-Haffner, J.2
Adelman, J.P.3
McCleskey, E.W.4
-
44
-
-
84864861302
-
Structure of the acid-sensing ion channel 1 in complex with the gating modifier psalmotoxin 1
-
Dawson RJ, Benz J, Stohler P, Tetaz T, Joseph C, Huber S, Schmid G, Hugin D, Pflimlin P, Trube G, Rudolph MG, Hennig M, Ruf A. Structure of the acid-sensing ion channel 1 in complex with the gating modifier psalmotoxin 1. Nat Commun 3: 936, 2012.
-
(2012)
Nat Commun
, vol.3
, pp. 936
-
-
Dawson, R.J.1
Benz, J.2
Stohler, P.3
Tetaz, T.4
Joseph, C.5
Huber, S.6
Schmid, G.7
Hugin, D.8
Pflimlin, P.9
Trube, G.10
Rudolph, M.G.11
Hennig, M.12
Ruf, A.13
-
46
-
-
0032555350
-
Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel
-
De Weille JR, Bassilana F, Lazdunski M, Waldmann R. Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel. FEBS Lett 433: 257-260, 1998.
-
(1998)
FEBS Lett
, vol.433
, pp. 257-260
-
-
de Weille, J.R.1
Bassilana, F.2
Lazdunski, M.3
Waldmann, R.4
-
47
-
-
0037379464
-
Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability
-
Deval E, Baron A, Lingueglia E, Mazarguil H, Zajac JM, Lazdunski M. Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability. Neuropharmacology 44: 662-671, 2003.
-
(2003)
Neuropharmacology
, vol.44
, pp. 662-671
-
-
Deval, E.1
Baron, A.2
Lingueglia, E.3
Mazarguil, H.4
Zajac, J.M.5
Lazdunski, M.6
-
48
-
-
78049273246
-
Acid-sensing ion channels (ASICs): Pharmacology and implication in pain
-
Deval E, Gasull X, Noel J, Salinas M, Baron A, Diochot S, Lingueglia E. Acid-sensing ion channels (ASICs): pharmacology and implication in pain. Pharmacol Ther 128: 549-558, 2010.
-
(2010)
Pharmacol Ther
, vol.128
, pp. 549-558
-
-
Deval, E.1
Gasull, X.2
Noel, J.3
Salinas, M.4
Baron, A.5
Diochot, S.6
Lingueglia, E.7
-
49
-
-
79955787546
-
Acid-sensing ion channels in postoperative pain
-
Deval E, Noel J, Gasull X, Delaunay A, Alloui A, Friend V, Eschalier A, Lazdunski M, Lingueglia E. Acid-sensing ion channels in postoperative pain. J Neurosci 31: 6059-6066, 2011.
-
(2011)
J Neurosci
, vol.31
, pp. 6059-6066
-
-
Deval, E.1
Noel, J.2
Gasull, X.3
Delaunay, A.4
Alloui, A.5
Friend, V.6
Eschalier, A.7
Lazdunski, M.8
Lingueglia, E.9
-
50
-
-
79951542315
-
Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASICla channels to extracellular acidosis
-
Duan B, Wang YZ, Yang T, Chu XP, Yu Y, Huang Y, Cao H, Hansen J, Simon RP, Zhu MX, Xiong ZG, Xu TL. Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASICla channels to extracellular acidosis. J Neurosci 31: 2101-2112, 2011.
-
(2011)
J Neurosci
, vol.31
, pp. 2101-2112
-
-
Duan, B.1
Wang, Y.Z.2
Yang, T.3
Chu, X.P.4
Yu, Y.5
Huang, Y.6
Cao, H.7
Hansen, J.8
Simon, R.P.9
Zhu, M.X.10
Xiong, Z.G.11
Xu, T.L.12
-
51
-
-
67650627679
-
Acid sensing ion channels and acid nociception
-
Dube GR, Elagoz A, Mangat H. Acid sensing ion channels and acid nociception. Curr Pharm Des 15: 1750-1766, 2009.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 1750-1766
-
-
Dube, G.R.1
Elagoz, A.2
Mangat, H.3
-
52
-
-
0037634059
-
Recombinant production and solution structure of PcTxl, the specific peptide inhibitor of ASICla proton-gated cation channels
-
Escoubas P, Bernard C, Lambeau G, Lazdunski M, Darbon H. Recombinant production and solution structure of PcTxl, the specific peptide inhibitor of ASICla proton-gated cation channels. Protein Sci 12: 1332-1343, 2003.
-
(2003)
Protein Sci
, vol.12
, pp. 1332-1343
-
-
Escoubas, P.1
Bernard, C.2
Lambeau, G.3
Lazdunski, M.4
Darbon, H.5
-
53
-
-
0034682749
-
+ channels
-
+ channels. J Biol Chem 275: 25116-25121, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 25116-25121
-
-
Escoubas, P.1
de Weille, J.R.2
Lecoq, A.3
Diochot, S.4
Waldmann, R.5
Champigny, G.6
Moinier, D.7
Menez, A.8
Lazdunski, M.9
-
54
-
-
33744988614
-
Silencing acid-sensing ion channel la alters cone-mediated retinal function
-
Ettaiche M, Deval E, Cougnon M, Lazdunski M, Voilley N. Silencing acid-sensing ion channel la alters cone-mediated retinal function. J Neurosci 26: 5800-5809, 2006.
-
(2006)
J Neurosci
, vol.26
, pp. 5800-5809
-
-
Ettaiche, M.1
Deval, E.2
Cougnon, M.3
Lazdunski, M.4
Voilley, N.5
-
55
-
-
65549122579
-
Acid-sensing ion channel 3 in retinal function and survival
-
Ettaiche M, Deval E, Pagnotta S, Lazdunski M, Lingueglia E. Acid-sensing ion channel 3 in retinal function and survival. Invest Ophthalmol Vis Sci 50: 2417-2426, 2009.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 2417-2426
-
-
Ettaiche, M.1
Deval, E.2
Pagnotta, S.3
Lazdunski, M.4
Lingueglia, E.5
-
56
-
-
0842347349
-
Acid-sensing ion channel 2 is important for retinal function and protects against light-induced retinal degeneration
-
Ettaiche M, Guy N, Hofman P, Lazdunski M, Waldmann R. Acid-sensing ion channel 2 is important for retinal function and protects against light-induced retinal degeneration. J Neurosci 24: 1005-1012, 2004.
-
(2004)
J Neurosci
, vol.24
, pp. 1005-1012
-
-
Ettaiche, M.1
Guy, N.2
Hofman, P.3
Lazdunski, M.4
Waldmann, R.5
-
57
-
-
36849009834
-
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system
-
Friese MA, Craner MJ, Etzensperger R, Vergo S, Wemmie JA, Welsh MJ, Vincent A, Fugger L. Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system. Nat Med 13: 1483-1489, 2007.
-
(2007)
Nat Med
, vol.13
, pp. 1483-1489
-
-
Friese, M.A.1
Craner, M.J.2
Etzensperger, R.3
Vergo, S.4
Wemmie, J.A.5
Welsh, M.J.6
Vincent, A.7
Fugger, L.8
-
58
-
-
0031029967
-
BNaCl and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels
-
Garcia-Anoveros J, Derfler B, Neville-Golden J, Hyman BT, Corey DP. BNaCl and BNaC2 constitute a new family of human neuronal sodium channels related to degenerins and epithelial sodium channels. Proc Natl Acad Sci USA 94: 1459-1464, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1459-1464
-
-
Garcia-Anoveros, J.1
Derfler, B.2
Neville-Golden, J.3
Hyman, B.T.4
Corey, D.P.5
-
59
-
-
67949092829
-
Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
-
Gonzales EB, Kawate T, Gouaux E. Pore architecture and ion sites in acid-sensing ion channels and P2X receptors. Nature 460: 599-604, 2009.
-
(2009)
Nature
, vol.460
, pp. 599-604
-
-
Gonzales, E.B.1
Kawate, T.2
Gouaux, E.3
-
60
-
-
77954727554
-
Structure, function, and pharmacology of acid-sensing ion channels (ASICs): Focus on ASICla
-
Grunder S, Chen X. Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASICla. Int J Physiol Pathophysiol Pharmacol 2: 73-94, 2010.
-
(2010)
Int J Physiol Pathophysiol Pharmacol
, vol.2
, pp. 73-94
-
-
Grunder, S.1
Chen, X.2
-
61
-
-
0344743590
-
A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel
-
Grunder S, Firsov D, Chang SS, Jaeger NF, Gautschi I, Schild L, Lifton RP, Rossier BC. A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel. EMBO J 16: 899-907, 1997.
-
(1997)
EMBO J
, vol.16
, pp. 899-907
-
-
Grunder, S.1
Firsov, D.2
Chang, S.S.3
Jaeger, N.F.4
Gautschi, I.5
Schild, L.6
Lifton, R.P.7
Rossier, B.C.8
-
62
-
-
0034608606
-
A new member of acid-sensing ion channels from pituitary gland
-
Grunder S, Geissler HS, Bassler EL, Ruppersberg JP. A new member of acid-sensing ion channels from pituitary gland. Neuroreport 11: 1607-1611, 2000.
-
(2000)
Neuroreport
, vol.11
, pp. 1607-1611
-
-
Grunder, S.1
Geissler, H.S.2
Bassler, E.L.3
Ruppersberg, J.P.4
-
63
-
-
1642524428
-
pH Dependency and desensitization kinetics of heterologously expressed combinations of acid-sensing ion channel subunits
-
Hesselager M, Timmermann DB, Ahring PK. pH Dependency and desensitization kinetics of heterologously expressed combinations of acid-sensing ion channel subunits. J Biol Chem 279: 11006-11015, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 11006-11015
-
-
Hesselager, M.1
Timmermann, D.B.2
Ahring, P.K.3
-
64
-
-
78650633367
-
Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant
-
Hoagland EN, Sherwood TW, Lee KG, Walker CJ, Askwith CC. Identification of a calcium permeable human acid-sensing ion channel 1 transcript variant. J Biol Chem 285: 41852-41862, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 41852-41862
-
-
Hoagland, E.N.1
Sherwood, T.W.2
Lee, K.G.3
Walker, C.J.4
Askwith, C.C.5
-
65
-
-
70349916098
-
Acid-sensitive ion channels and receptors
-
Holzer P. Acid-sensitive ion channels and receptors. Handb Exp Pharmacol 194: 283-332, 2009.
-
(2009)
Handb Exp Pharmacol
, vol.194
, pp. 283-332
-
-
Holzer, P.1
-
66
-
-
77956595453
-
Existence and distinction of acid-evoked currents in rat astrocytes
-
Huang C, Hu ZL, Wu WN, Yu DF, Xiong QJ, Song JR, Shu Q, Fu H, Wang F, Chen JG. Existence and distinction of acid-evoked currents in rat astrocytes. Glia 58: 1415-1424, 2010.
-
(2010)
Glia
, vol.58
, pp. 1415-1424
-
-
Huang, C.1
Hu, Z.L.2
Wu, W.N.3
Yu, D.F.4
Xiong, Q.J.5
Song, J.R.6
Shu, Q.7
Fu, H.8
Wang, F.9
Chen, J.G.10
-
68
-
-
0032540129
-
Molecular cloning of a DEG/ENaC sodium channel cDNA from human testis
-
Ishibashi K, Marumo F. Molecular cloning of a DEG/ENaC sodium channel cDNA from human testis. Biochem Biophys Res Commun 245: 589-593, 1998.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 589-593
-
-
Ishibashi, K.1
Marumo, F.2
-
69
-
-
79951867457
-
Proton-binding sites of acid-sensing ion channel 1
-
Ishikita H. Proton-binding sites of acid-sensing ion channel 1. PLos One 6: el6920, 2011.
-
(2011)
PLos One
, vol.6
-
-
Ishikita, H.1
-
70
-
-
25844502468
-
Identification of acid-sensing ion channels in bone
-
Jahr H, van Driel M, van Osch GJ, Weinans H, van Leeuwen JP. Identification of acid-sensing ion channels in bone. Biochem Biophys Res Commun 337: 349-354, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 349-354
-
-
Jahr, H.1
van Driel, M.2
van Osch, G.J.3
Weinans, H.4
van Leeuwen, J.P.5
-
71
-
-
34548813656
-
Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH
-
Jasti J, Furukawa H, Gonzales EB, Gouaux E. Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH. Nature 449: 316-323, 2007.
-
(2007)
Nature
, vol.449
, pp. 316-323
-
-
Jasti, J.1
Furukawa, H.2
Gonzales, E.B.3
Gouaux, E.4
-
72
-
-
80052476803
-
Cysteine 149 in the extracellular finger domain of acid-sensing ion channel lb subunit is critical for zinc-mediated inhibition
-
Jiang Q, Inoue K, Wu X, Papasian CJ, Wang JQ, Xiong ZG, Chu XP. Cysteine 149 in the extracellular finger domain of acid-sensing ion channel lb subunit is critical for zinc-mediated inhibition. Neuroscience 193: 89-99, 2011.
-
(2011)
Neuroscience
, vol.193
, pp. 89-99
-
-
Jiang, Q.1
Inoue, K.2
Wu, X.3
Papasian, C.J.4
Wang, J.Q.5
Xiong, Z.G.6
Chu, X.P.7
-
73
-
-
84863338636
-
W-glycosylation of acid-sensing ion channel la regulates its trafficking and acidosis-induced spine remodeling
-
Jing L, Chu XP, Jiang YQ, Collier DM, Wang B, Jiang Q, Snyder PM, Zha XM. W-glycosylation of acid-sensing ion channel la regulates its trafficking and acidosis-induced spine remodeling. J Neurosci 32: 4080-4091, 2012.
-
(2012)
J Neurosci
, vol.32
, pp. 4080-4091
-
-
Jing, L.1
Chu, X.P.2
Jiang, Y.Q.3
Collier, D.M.4
Wang, B.5
Jiang, Q.6
Snyder, P.M.7
Zha, X.M.8
-
75
-
-
45349085032
-
Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) la and ASIC lb
-
Kadurin I, Golubovic A, Leisle L, Schindelin H, Grander S. Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) la and ASIC lb. Biochem J 412: 469-475, 2008.
-
(2008)
Biochem J
, vol.412
, pp. 469-475
-
-
Kadurin, I.1
Golubovic, A.2
Leisle, L.3
Schindelin, H.4
Grander, S.5
-
76
-
-
0028123661
-
Acidosis induced by hypercapnia exaggerates ischemic brain damage
-
Katsura K, Kristian T, Smith ML, Siesjo BK. Acidosis induced by hypercapnia exaggerates ischemic brain damage. J Cereb Blood Flow Metab 14: 243-250, 1994.
-
(1994)
J Cereb Blood Flow Metab
, vol.14
, pp. 243-250
-
-
Katsura, K.1
Kristian, T.2
Smith, M.L.3
Siesjo, B.K.4
-
77
-
-
0036307827
-
Epithelial sodium channel/degenerin family of ion channels: A variety of functions for a shared structure
-
Kellenberger S, Schild L. Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure. Physiol Rev 82: 735-767, 2002.
-
(2002)
Physiol Rev
, vol.82
, pp. 735-767
-
-
Kellenberger, S.1
Schild, L.2
-
78
-
-
0019185036
-
A receptor for protons in the nerve cell membrane
-
Krishtal OA, Pidoplichko VI. A receptor for protons in the nerve cell membrane. Neuroscience 5: 2325-2327, 1980.
-
(1980)
Neuroscience
, vol.5
, pp. 2325-2327
-
-
Krishtal, O.A.1
Pidoplichko, V.I.2
-
79
-
-
77952943039
-
Extracellular chloride modulates the desensitization kinetics of acid-sensing ion channel la (ASICla)
-
Kusama N, Harding AM, Benson CJ. Extracellular chloride modulates the desensitization kinetics of acid-sensing ion channel la (ASICla). J Biol Chem 285: 17425-17431, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 17425-17431
-
-
Kusama, N.1
Harding, A.M.2
Benson, C.J.3
-
80
-
-
48149111510
-
Gating the pore of P2X receptor channels
-
Li M, Chang TH, Silberberg SD, Swartz KJ. Gating the pore of P2X receptor channels. Nat Neurosci 11: 883-887, 2008.
-
(2008)
Nat Neurosci
, vol.11
, pp. 883-887
-
-
Li, M.1
Chang, T.H.2
Silberberg, S.D.3
Swartz, K.J.4
-
81
-
-
84880308941
-
Pore-opening mechanism in trimeric P2X receptor channels
-
Li M, Kawate T, Silberberg SD, Swartz KJ. Pore-opening mechanism in trimeric P2X receptor channels. Nat Commun 1: 44, 2010.
-
(2010)
Nat Commun
, vol.1
, pp. 44
-
-
Li, M.1
Kawate, T.2
Silberberg, S.D.3
Swartz, K.J.4
-
82
-
-
77957797513
-
Asn415 in the betall-betal2 linker decreases proton-dependent desensitization of ASICl
-
Li T, Yang Y, Canessa CM. Asn415 in the betall-betal2 linker decreases proton-dependent desensitization of ASICl. J Biol Chem 285: 31285-31291, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 31285-31291
-
-
Li, T.1
Yang, Y.2
Canessa, C.M.3
-
84
-
-
63249117189
-
Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels
-
Li T, Yang Y, Canessa CM. Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels. J Biol Chem 284: 4689-4694, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 4689-4694
-
-
Li, T.1
Yang, Y.2
Canessa, C.M.3
-
85
-
-
77954611622
-
Leu85 in the betal-beta2 linker of ASICl slows activation and decreases the apparent proton affinity by stabilizing a closed conformation
-
Li T, Yang Y, Canessa CM. Leu85 in the betal-beta2 linker of ASICl slows activation and decreases the apparent proton affinity by stabilizing a closed conformation. J Biol Chem 285: 22706-22712, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 22706-22712
-
-
Li, T.1
Yang, Y.2
Canessa, C.M.3
-
86
-
-
79960585260
-
Outlines of the pore in open and closed conformations describe the gating mechanism of ASICl
-
Li T, Yang Y, Canessa CM. Outlines of the pore in open and closed conformations describe the gating mechanism of ASICl. Nat Commun 2: 399, 2011.
-
(2011)
Nat Commun
, vol.2
, pp. 399
-
-
Li, T.1
Yang, Y.2
Canessa, C.M.3
-
87
-
-
77953754779
-
Two residues in the extracellular domain convert a nonfunctional ASICl into a proton-activated channel
-
Li T, Yang Y, Canessa CM. Two residues in the extracellular domain convert a nonfunctional ASICl into a proton-activated channel. Am J Physiol Cell Physiol 299: C66-C73, 2010.
-
(2010)
Am J Physiol Cell Physiol
, vol.299
-
-
Li, T.1
Yang, Y.2
Canessa, C.M.3
-
88
-
-
82755176257
-
Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride
-
Li WG, Yu Y, Huang C, Cao H, Xu TL. Nonproton ligand sensing domain is required for paradoxical stimulation of acid-sensing ion channel 3 (ASIC3) channels by amiloride. J Biol Chem 286: 42635-42646, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 42635-42646
-
-
Li, W.G.1
Yu, Y.2
Huang, C.3
Cao, H.4
Xu, T.L.5
-
89
-
-
78649785634
-
ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain
-
Li WG, Yu Y, Zhang ZD, Cao H, Xu TL. ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain. Mol Pain 6: 88, 2011.
-
(2011)
Mol Pain
, vol.6
, pp. 88
-
-
Li, W.G.1
Yu, Y.2
Zhang, Z.D.3
Cao, H.4
Xu, T.L.5
-
90
-
-
77952365948
-
A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASICla
-
Liechti LA, Berneche S, Bargeton B, Iwaszkiewicz J, Roy S, Michie-lin O, Kellenberger S. A combined computational and functional approach identifies new residues involved in pH-dependent gating of ASICla. J Biol Chem 285: 16315-16329, 2008.
-
(2008)
J Biol Chem
, vol.285
, pp. 16315-16329
-
-
Liechti, L.A.1
Berneche, S.2
Bargeton, B.3
Iwaszkiewicz, J.4
Roy, S.5
Michie-Lin, O.6
Kellenberger, S.7
-
92
-
-
0030709246
-
A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells
-
Lingueglia E, de Weille JR, Bassilana F, Heurteaux C, Sakai H, Waldmann R, Lazdunski M. A modulatory subunit of acid sensing ion channels in brain and dorsal root ganglion cells. J Biol Chem 272: 29778-29783, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 29778-29783
-
-
Lingueglia, E.1
de Weille, J.R.2
Bassilana, F.3
Heurteaux, C.4
Sakai, H.5
Waldmann, R.6
Lazdunski, M.7
-
93
-
-
4744355819
-
Modulatory action of RFamide-related peptides on acid-sensing ionic channels is pH dependent: The role of arginine
-
Ostrovskaya O, Moroz L, Krishtal O. Modulatory action of RFamide-related peptides on acid-sensing ionic channels is pH dependent: the role of arginine. J Neurochem 91: 252-255, 2004.
-
(2004)
J Neurochem
, vol.91
, pp. 252-255
-
-
Ostrovskaya, O.1
Moroz, L.2
Krishtal, O.3
-
94
-
-
25444506199
-
Different contributions of ASIC channels la, 2, and 3 in gastrointestinal mechanosensory function
-
Page AJ, Brierley SM, Martin CM, Price MP, Symonds E, Butler R, Wemmie JA, Blackshaw LA. Different contributions of ASIC channels la, 2, and 3 in gastrointestinal mechanosensory function. Gut 54: 1408-1415, 2005.
-
(2005)
Gut
, vol.54
, pp. 1408-1415
-
-
Page, A.J.1
Brierley, S.M.2
Martin, C.M.3
Price, M.P.4
Symonds, E.5
Butler, R.6
Wemmie, J.A.7
Blackshaw, L.A.8
-
95
-
-
73649085483
-
Conformational changes associated with proton-dependent gating of ASICla
-
Passero CJ, Okumura S, Carattino MD. Conformational changes associated with proton-dependent gating of ASICla. J Biol Chem 284: 36473-36481, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 36473-36481
-
-
Passero, C.J.1
Okumura, S.2
Carattino, M.D.3
-
96
-
-
5144227428
-
2+ blocking site of acid-sensing ion channel (ASIC) 1: Implications for channel gating
-
2+ blocking site of acid-sensing ion channel (ASIC) 1: implications for channel gating. J Gen Physiol 124: 383-394, 2004.
-
(2004)
J Gen Physiol
, vol.124
, pp. 383-394
-
-
Paukert, M.1
Babini, E.2
Pusch, M.3
Grander, S.4
-
98
-
-
4444221565
-
UCSF Chimera-a visualization system for exploratory research and analysis
-
Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE. UCSF Chimera-a visualization system for exploratory research and analysis. J Comput Chem 25: 1605-1612, 2004.
-
(2004)
J Comput Chem
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
Goddard, T.D.2
Huang, C.C.3
Couch, G.S.4
Greenblatt, D.M.5
Meng, E.C.6
Ferrin, T.E.7
-
99
-
-
33744959734
-
A gating mutation in the internal pore of ASIC la
-
Pfister Y, Gautschi I, Takeda AN, van Bemmelen M, Kellenberger S, Schild L. A gating mutation in the internal pore of ASIC la. Biol Chem 281: 11787-11791, 2006.
-
(2006)
Biol Chem
, vol.281
, pp. 11787-11791
-
-
Pfister, Y.1
Gautschi, I.2
Takeda, A.N.3
van Bemmelen, M.4
Kellenberger, S.5
Schild, L.6
-
100
-
-
79955921972
-
On the putative binding site of RFamide-family neuropeptides from the western Atlantic clam Sunray Venus and cephalopods on acid-sensing ion channels. An automated docking and molecular-dynamics study with hASICla homology model
-
Pietra F. On the putative binding site of RFamide-family neuropeptides from the western Atlantic clam Sunray Venus and cephalopods on acid-sensing ion channels. An automated docking and molecular-dynamics study with hASICla homology model. Chem Biodivers 8: 816-826, 2011.
-
(2011)
Chem Biodivers
, vol.8
, pp. 816-826
-
-
Pietra, F.1
-
101
-
-
33845897638
-
Prolonged activation of ASICla and the time window for neuroprotection in cerebral ischaemia
-
Pignataro G, Simon RP, Xiong ZG. Prolonged activation of ASICla and the time window for neuroprotection in cerebral ischaemia. Brain 130: 151-158, 2007.
-
(2007)
Brain
, vol.130
, pp. 151-158
-
-
Pignataro, G.1
Simon, R.P.2
Xiong, Z.G.3
-
102
-
-
4644243948
-
Selective regulation of acid-sensing ion channel 1 by serine proteases
-
Poirot O, Vukicevic M, Boesch A, Kellenberger S. Selective regulation of acid-sensing ion channel 1 by serine proteases. J Biol Chem 279: 38448-38457, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 38448-38457
-
-
Poirot, O.1
Vukicevic, M.2
Boesch, A.3
Kellenberger, S.4
-
103
-
-
0029922113
-
Cloning and expression of a novel human brain Na+ channel
-
Price MP, Snyder PM, Welsh MJ. Cloning and expression of a novel human brain Na+ channel. J Biol Chem 111: 7879-7882, 1996.
-
(1996)
J Biol Chem
, vol.111
, pp. 7879-7882
-
-
Price, M.P.1
Snyder, P.M.2
Welsh, M.J.3
-
104
-
-
67650543860
-
Psalmotoxin-1 docking to human acid-sensing ion channel-1
-
Qadri YJ, Berdiev BK, Song Y, Lippton HL, Fuller CM, Benos DJ. Psalmotoxin-1 docking to human acid-sensing ion channel-1. J Biol Chem 284: 17625-17633, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 17625-17633
-
-
Qadri, Y.J.1
Berdiev, B.K.2
Song, Y.3
Lippton, H.L.4
Fuller, C.M.5
Benos, D.J.6
-
105
-
-
77951223851
-
Amiloride docking to acid-sensing ion channel-1
-
Qadri YJ, Song Y, Fuller CM, Benos DJ. Amiloride docking to acid-sensing ion channel-1. J Biol Chem 285: 9627-9635, 2012.
-
(2012)
J Biol Chem
, vol.285
, pp. 9627-9635
-
-
Qadri, Y.J.1
Song, Y.2
Fuller, C.M.3
Benos, D.J.4
-
106
-
-
80054777668
-
A dynamic pharmaco-phore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel la
-
Saez NJ, Mobli M, Bieri M, Chassagnon IR, Malde AK, Gamsjaeger R, Mark AE, Gooley PR, Rash LD, King GF. A dynamic pharmaco-phore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel la. Mol Pharmacol 80: 796-808, 2011.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 796-808
-
-
Saez, N.J.1
Mobli, M.2
Bieri, M.3
Chassagnon, I.R.4
Malde, A.K.5
Gamsjaeger, R.6
Mark, A.E.7
Gooley, P.R.8
Rash, L.D.9
King, G.F.10
-
107
-
-
70450273065
-
Structural elements for the generation of sustained currents by the acid pain sensor ASIC3
-
Salinas M, Lazdunski M, Lingueglia E. Structural elements for the generation of sustained currents by the acid pain sensor ASIC3. J Biol Chem 284: 31851-31859, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 31851-31859
-
-
Salinas, M.1
Lazdunski, M.2
Lingueglia, E.3
-
108
-
-
33644610311
-
The receptor site of the spider toxin PcTxl on the proton-gated cation channel ASICla
-
Salinas M, Rash LD, Baron A, Lambeau G, Escoubas P, Lazdunski M. The receptor site of the spider toxin PcTxl on the proton-gated cation channel ASICla. J Physiol 570: 339-354, 2006.
-
(2006)
J Physiol
, vol.570
, pp. 339-354
-
-
Salinas, M.1
Rash, L.D.2
Baron, A.3
Lambeau, G.4
Escoubas, P.5
Lazdunski, M.6
-
109
-
-
11244269414
-
Analysis of the membrane topology of the acid-sensing ion channel 2a
-
Saugstad JA, Roberts JA, Dong J, Zeitouni S, Evans RJ. Analysis of the membrane topology of the acid-sensing ion channel 2a. J Biol Chem 279: 55514-55519, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 55514-55519
-
-
Saugstad, J.A.1
Roberts, J.A.2
Dong, J.3
Zeitouni, S.4
Evans, R.J.5
-
110
-
-
0031017054
-
Identification of amino acid residues in the alpha, beta, and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation
-
Schild L, Schneeberger E, Gautschi I, Firsov D. Identification of amino acid residues in the alpha, beta, and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation. J Gen Physiol 109: 15-26, 1997.
-
(1997)
J Gen Physiol
, vol.109
, pp. 15-26
-
-
Schild, L.1
Schneeberger, E.2
Gautschi, I.3
Firsov, D.4
-
111
-
-
58149332703
-
+ binding sites in acid sensing ion channel-1
-
+ binding sites in acid sensing ion channel-1. Biophys J 95: 5153-5164, 2008.
-
(2008)
Biophys J
, vol.95
, pp. 5153-5164
-
-
Shaikh, S.A.1
Tajkhorshid, E.2
-
112
-
-
70350441287
-
Identification of protein domains that control proton and calcium sensitivity of ASICla
-
Sherwood T, Franke R, Conneely S, Joyner J, Arumugan P, Askwith C. Identification of protein domains that control proton and calcium sensitivity of ASICla. J Biol Chem 284: 27899-27907, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 27899-27907
-
-
Sherwood, T.1
Franke, R.2
Conneely, S.3
Joyner, J.4
Arumugan, P.5
Askwith, C.6
-
113
-
-
70449623627
-
Dynorphin opioid peptides enhance acid-sensing ion channel la activity and acidosis-induced neuronal death
-
Sherwood TW, Askwith CC. Dynorphin opioid peptides enhance acid-sensing ion channel la activity and acidosis-induced neuronal death. J Neurosci 29: 14371-14380, 2009.
-
(2009)
J Neurosci
, vol.29
, pp. 14371-14380
-
-
Sherwood, T.W.1
Askwith, C.C.2
-
114
-
-
38349137692
-
Endogenous arginine-phenylalanine-amide-related peptides alter steady-state desensitization of ASICla
-
Sherwood TW, Askwith CC. Endogenous arginine-phenylalanine-amide-related peptides alter steady-state desensitization of ASICla. J Biol Chem 283: 1818-1830, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 1818-1830
-
-
Sherwood, T.W.1
Askwith, C.C.2
-
115
-
-
79960024474
-
Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASICla display novel channel properties and contribute to acidosis-induced neuronal death
-
Sherwood TW, Lee KG, Gormley MG, Askwith CC. Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASICla display novel channel properties and contribute to acidosis-induced neuronal death. J Neurosci 31: 9723-9734, 2011.
-
(2011)
J Neurosci
, vol.31
, pp. 9723-9734
-
-
Sherwood, T.W.1
Lee, K.G.2
Gormley, M.G.3
Askwith, C.C.4
-
116
-
-
0024153902
-
Acidosis and ischemic brain damage
-
Siesjo BK. Acidosis and ischemic brain damage. Neurochem Pathol 9: 31-88, 1988.
-
(1988)
Neurochem Pathol
, vol.9
, pp. 31-88
-
-
Siesjo, B.K.1
-
117
-
-
0029691053
-
Molecular mechanisms of acidosis-mediated damage
-
Siesjo BK, Katsura KI, Kristian T, Li PA, Siesjo P. Molecular mechanisms of acidosis-mediated damage. Ada Neurochir Suppl (Wien) 66: 8-14, 1996.
-
(1996)
Ada Neurochir Suppl (Wien)
, vol.66
, pp. 8-14
-
-
Siesjo, B.K.1
Katsura, K.I.2
Kristian, T.3
Li, P.A.4
Siesjo, P.5
-
118
-
-
0344305593
-
Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1
-
Sluka KA, Price MP, Breese NM, Stucky CL, Wemmie JA, Welsh MJ. Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1. Pain 106: 229-239, 2003.
-
(2003)
Pain
, vol.106
, pp. 229-239
-
-
Sluka, K.A.1
Price, M.P.2
Breese, N.M.3
Stucky, C.L.4
Wemmie, J.A.5
Welsh, M.J.6
-
120
-
-
34548831941
-
Proton binding sites involved in the activation of acid-sensing ion channel ASIC2a
-
Smith ES, Zhang X, Cadiou H, McNaughton PA. Proton binding sites involved in the activation of acid-sensing ion channel ASIC2a. Neurosci Lett 426: 12-17, 2007.
-
(2007)
Neurosci Lett
, vol.426
, pp. 12-17
-
-
Smith, E.S.1
Zhang, X.2
Cadiou, H.3
McNaughton, P.A.4
-
121
-
-
79959888193
-
The interaction between two extracellular linker regions controls sustained opening of acid-sensing ion channel 1
-
Springauf A, Bresenitz P, Grander S. The interaction between two extracellular linker regions controls sustained opening of acid-sensing ion channel 1. J Biol Chem 286: 24374-24384, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 24374-24384
-
-
Springauf, A.1
Bresenitz, P.2
Grander, S.3
-
122
-
-
25144484824
-
Effects of extracellular calcium on fASICl currents
-
Todorovic N, Cork T, Zhang P, Canessa C. Effects of extracellular calcium on fASICl currents. Ann NY Acad Sci 1048: 331-336, 2005.
-
(2005)
Ann NY Acad Sci
, vol.1048
, pp. 331-336
-
-
Todorovic, N.1
Cork, T.2
Zhang, P.3
Canessa, C.4
-
123
-
-
79955546832
-
Insights into the mechanism of pore opening of acid-sensing ion channel la
-
Tolino LA, Okumura S, Kashlan OB, Carattino MD. Insights into the mechanism of pore opening of acid-sensing ion channel la. Biol Chem 286: 16297-16307, 2011.
-
(2011)
Biol Chem
, vol.286
, pp. 16297-16307
-
-
Tolino, L.A.1
Okumura, S.2
Kashlan, O.B.3
Carattino, M.D.4
-
124
-
-
79551700814
-
Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model
-
Vergo S, Craner MJ, Etzensperger R, Attfield K, Friese MA, New-combe J, Esiri M, Fugger L. Acid-sensing ion channel 1 is involved in both axonal injury and demyelination in multiple sclerosis and its animal model. Brain 134: 571-584, 2011.
-
(2011)
Brain
, vol.134
, pp. 571-584
-
-
Vergo, S.1
Craner, M.J.2
Etzensperger, R.3
Attfield, K.4
Friese, M.A.5
New-Combe, J.6
Esiri, M.7
Fugger, L.8
-
125
-
-
33644861783
-
Trypsin cleaves acid-sensing ion channel la in a domain that is critical for channel gating
-
Vukicevic M, Weder G, Boillat A, Boesch A, Kellenberger S. Trypsin cleaves acid-sensing ion channel la in a domain that is critical for channel gating. J Biol Chem 281: 714-722, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 714-722
-
-
Vukicevic, M.1
Weder, G.2
Boillat, A.3
Boesch, A.4
Kellenberger, S.5
-
127
-
-
0030946297
-
A proton-gated cation channel involved in acid-sensing
-
Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M. A proton-gated cation channel involved in acid-sensing. Nature 386: 173-177, 1997.
-
(1997)
Nature
, vol.386
, pp. 173-177
-
-
Waldmann, R.1
Champigny, G.2
Bassilana, F.3
Heurteaux, C.4
Lazdunski, M.5
-
128
-
-
15844415068
-
The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans
-
Waldmann R, Champigny G, Voilley N, Lauritzen I, Lazdunski M. The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans. J Biol Chem 271: 10433-10436, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 10433-10436
-
-
Waldmann, R.1
Champigny, G.2
Voilley, N.3
Lauritzen, I.4
Lazdunski, M.5
-
130
-
-
0038384013
-
Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning
-
Wemmie JA, Askwith CC, Lamani E, Cassell MD, Freeman JH Jr, Welsh MJ. Acid-sensing ion channel 1 is localized in brain regions with high synaptic density and contributes to fear conditioning. J Neurosci 23: 5496-5502, 2003.
-
(2003)
J Neurosci
, vol.23
, pp. 5496-5502
-
-
Wemmie, J.A.1
Askwith, C.C.2
Lamani, E.3
Cassell, M.D.4
Freeman Jr., J.H.5
Welsh, M.J.6
-
131
-
-
1542723399
-
Overexpression of acid-sensing ion channel la in transgenic mice increases acquired fear-related behavior
-
Wemmie JA, Coryell MW, Askwith CC, Lamani E, Leonard AS, Sigmund CD, Welsh MJ. Overexpression of acid-sensing ion channel la in transgenic mice increases acquired fear-related behavior. Proc Natl Acad Sci USA 101: 3621-3626, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3621-3626
-
-
Wemmie, J.A.1
Coryell, M.W.2
Askwith, C.C.3
Lamani, E.4
Leonard, A.S.5
Sigmund, C.D.6
Welsh, M.J.7
-
132
-
-
33748797928
-
Acid-sensing ion channels: Advances, questions and therapeutic opportunities
-
Wemmie JA, Price MP, Welsh MJ. Acid-sensing ion channels: advances, questions and therapeutic opportunities. Trends Neurosci 29: 578-586, 2006.
-
(2006)
Trends Neurosci
, vol.29
, pp. 578-586
-
-
Wemmie, J.A.1
Price, M.P.2
Welsh, M.J.3
-
134
-
-
33646552708
-
2+-permeable acid-sensing ion channels and ischemic brain injury
-
2+-permeable acid-sensing ion channels and ischemic brain injury. J Membr Biol 209: 59-68, 2006.
-
(2006)
J Membr Biol
, vol.209
, pp. 59-68
-
-
Xiong, Z.G.1
Chu, X.P.2
Simon, R.P.3
-
135
-
-
38649129918
-
Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases
-
Xiong ZG, Pignataro G, Li M, Chang SY, Simon RP. Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases. Curr Opin Pharmacol 8: 25-32, 2008.
-
(2008)
Curr Opin Pharmacol
, vol.8
, pp. 25-32
-
-
Xiong, Z.G.1
Pignataro, G.2
Li, M.3
Chang, S.Y.4
Simon, R.P.5
-
136
-
-
4544230902
-
Neuroprotec-tion in ischemia: Blocking calcium-permeable acid-sensing ion channels
-
Xiong ZG, Zhu XM, Chu XP, Minami M, Hey J, Wei WL, MacDon-ald JF, Wemmie JA, Price MP, Welsh MJ, Simon RP. Neuroprotec-tion in ischemia: blocking calcium-permeable acid-sensing ion channels. Cell 118: 687-698, 2004.
-
(2004)
Cell
, vol.118
, pp. 687-698
-
-
Xiong, Z.G.1
Zhu, X.M.2
Chu, X.P.3
Minami, M.4
Hey, J.5
Wei, W.L.6
Macdon-Ald, J.F.7
Wemmie, J.A.8
Price, M.P.9
Welsh, M.J.10
Simon, R.P.11
-
137
-
-
68749103490
-
Conformational sampling on acid-sensing ion channel 1 (ASIC1): Implication for a symmetric conformation
-
Yang H, Yu Y, Li WG, Xu TL, Jiang H. Conformational sampling on acid-sensing ion channel 1 (ASIC1): implication for a symmetric conformation. Cell Res 19: 1035-1037, 2009.
-
(2009)
Cell Res
, vol.19
, pp. 1035-1037
-
-
Yang, H.1
Yu, Y.2
Li, W.G.3
Xu, T.L.4
Jiang, H.5
-
138
-
-
68049145097
-
Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism
-
Yang H, Yu Y, Li WG, Yu F, Cao H, Xu TL, Jiang H. Inherent dynamics of the acid-sensing ion channel 1 correlates with the gating mechanism. PLoS Biol 7: el000151, 2009.
-
(2009)
PLoS Biol
, vol.7
-
-
Yang, H.1
Yu, Y.2
Li, W.G.3
Yu, F.4
Cao, H.5
Xu, T.L.6
Jiang, H.7
-
139
-
-
84860352363
-
Highly conserved salt bridge stabilizes rigid signal patch at extracellular loop critical for surface expression of acid-sensing ion channels
-
Yang Y, Yu Y, Cheng J, Liu Y, Liu DS, Wang J, Zhu MX, Wang R, Xu TL. Highly conserved salt bridge stabilizes rigid signal patch at extracellular loop critical for surface expression of acid-sensing ion channels. J Biol Chem 287: 14443-14455, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 14443-14455
-
-
Yang, Y.1
Yu, Y.2
Cheng, J.3
Liu, Y.4
Liu, D.S.5
Wang, J.6
Zhu, M.X.7
Wang, R.8
Xu, T.L.9
-
140
-
-
77954176463
-
Acid-sensing ion channel (ASIC) la undergoes a height transition in response to acidification
-
Yokokawa M, Carnally SM, Henderson RM, Takeyasu K, Edward-son JM. Acid-sensing ion channel (ASIC) la undergoes a height transition in response to acidification. FEBS Lett 584: 3107-3110, 2010.
-
(2010)
FEBS Lett
, vol.584
, pp. 3107-3110
-
-
Yokokawa, M.1
Carnally, S.M.2
Henderson, R.M.3
Takeyasu, K.4
Edward-Son, J.M.5
-
141
-
-
77957293978
-
A nonproton ligand sensor in the acid-sensing ion channel
-
Yu Y, Chen Z, Li WG, Cao H, Feng EG, Yu F, Liu H, Jiang H, Xu TL. A nonproton ligand sensor in the acid-sensing ion channel. Neuron 68: 61-72, 2010.
-
(2010)
Neuron
, vol.68
, pp. 61-72
-
-
Yu, Y.1
Chen, Z.2
Li, W.G.3
Cao, H.4
Feng, E.G.5
Yu, F.6
Liu, H.7
Jiang, H.8
Xu, T.L.9
-
142
-
-
79960127490
-
Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels
-
Yu Y, Li WG, Chen Z, Cao H, Yang H, Jiang H, Xu TL. Atomic level characterization of the nonproton ligand-sensing domain of ASIC3 channels. J Biol Chem 286: 24996-25006, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 24996-25006
-
-
Yu, Y.1
Li, W.G.2
Chen, Z.3
Cao, H.4
Yang, H.5
Jiang, H.6
Xu, T.L.7
-
144
-
-
70449753801
-
The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior
-
Ziemann AE, Allen JE, Dahdaleh NS, Drebot II, Coryell MW, Wunsch AM, Lynch CM, Faraci FM, Howard MA 3rd, Welsh MJ, Wemmie JA. The amygdala is a chemosensor that detects carbon dioxide and acidosis to elicit fear behavior. Cell 139: 1012-1021, 2009.
-
(2009)
Cell
, vol.139
, pp. 1012-1021
-
-
Ziemann, A.E.1
Allen, J.E.2
Dahdaleh, N.S.3
Drebot, I.I.4
Coryell, M.W.5
Wunsch, A.M.6
Lynch, C.M.7
Faraci, F.M.8
Howard III, M.A.9
Welsh, M.J.10
Wemmie, J.A.11
-
145
-
-
46049117310
-
Seizure termination by acidosis depends on ASICla
-
Ziemann AE, Schnizler MK, Albert GW, Severson MA, Howard MA 3rd, Welsh MJ, Wemmie JA. Seizure termination by acidosis depends on ASICla. Nat Neurosci 11: 816-822, 2008.
-
(2008)
Nat Neurosci
, vol.11
, pp. 816-822
-
-
Ziemann, A.E.1
Schnizler, M.K.2
Albert, G.W.3
Severson, M.A.4
Howard III, M.A.5
Welsh, M.J.6
Wemmie, J.A.7
|