Stabilization of Functional Recombinant Cannabinoid Receptor CB2 in Detergent Micelles and Lipid Bilayers

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Vukoti, Krishna ^a,b   Kimura, Tomohiro ^a   Macke, Laura ^a   Gawrisch, Klaus ^a   Yeliseev, Alexei ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [(3 CHOLAMIDOPROPYL)DIMETHYLAMMONIO] 1 PROPANESULFONIC ACID; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 5 (4 CHLORO 3 METHYLPHENYL) 1 (4 METHYLBENZYL) N (1,3,3 TRIMETHYLBICYCLO[2.2.1]HEPTAN 2 YL) 3 PYRAZOLECARBOXAMIDE; ANION; CANNABINOID; CANNABINOID 2 RECEPTOR; CHOLESTEROL HYDROGEN SUCCINATE; DETERGENT; DEUTERIUM; DODECYL MALTOSIDE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; LIPID; LIPOSOME; PHOSPHOLIPID; RECOMBINANT CANNABINOID 2 RECEPTOR; RECOMBINANT PROTEIN; SERINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ESCHERICHIA COLI; LIGAND BINDING; LIPID BILAYER; MICELLE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LIPID INTERACTION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; RECEPTOR BINDING; SOLID STATE;

DETERGENTS; ESCHERICHIA COLI; LIGANDS; LIPID BILAYERS; MICELLES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHOLIPIDS; RECEPTOR, CANNABINOID, CB2; RECOMBINANT PROTEINS; SOLUBILITY;

ESCHERICHIA COLI;

EID: 84867037561     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046290     Document Type: Article

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