Functional brain basis of hypnotizability

Archives of General Psychiatry

Volumn 69, Issue 10, 2012, Pages 1064-1072

  Hoeft, Fumiko ^a,b   Gabrieli, John D E ^c   Whitfield Gabrieli, Susan ^c   Haas, Brian W ^a   Bammer, Roland ^a   Menon, Vinod ^a   Spiegel, David ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ANTERIOR CINGULATE; ANTERIOR INSULA; ARTICLE; CORPUS STRIATUM; FEMALE; FUNCTIONAL ANATOMY; HUMAN; HUMAN EXPERIMENT; HYPNOTIC SUSCEPTIBILITY; MALE; NERVE CELL NETWORK; NEUROANATOMY; NORMAL HUMAN; PREFRONTAL CORTEX;

ADULT; BRAIN MAPPING; CEREBRAL CORTEX; CROSS-SECTIONAL STUDIES; DIFFUSION TENSOR IMAGING; EXECUTIVE FUNCTION; FEMALE; GYRUS CINGULI; HUMANS; HYPNOSIS; MAGNETIC RESONANCE IMAGING; MALE; NERVE NET; PREFRONTAL CORTEX; YOUNG ADULT;

EID: 84867036758     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archgenpsychiatry.2011.2190     Document Type: Article

References (82)

1. Lang EV, Berbaum KS, Faintuch S, Hatsiopoulou O, Halsey N, Li X, Berbaum ML, Laser E, Baum J. Adjunctive self-hypnotic relaxation for outpatient medical procedures: a prospective randomized trial with women undergoing large core breast biopsy. Pain. 2006;126(1-3):155-164. (Pubitemid 44781354)
2. Lang EV, Benotsch EG, Fick LJ, Lutgendorf S, Berbaum ML, Berbaum KS, Logan H, Spiegel D. Adjunctive non-pharmacological analgesia for invasive medical procedures: a randomised trial. Lancet. 2000;355(9214):1486-1490. (Pubitemid 30237354)
3. Montgomery GH, Bovbjerg DH, Schnur JB, David D, Goldfarb A, Weltz CR, Schechter C, Graff-Zivin J, Tatrow K, Price DD, Silverstein JH. A randomized clinical trial of a brief hypnosis intervention to control side effects in breast surgery patients. J Natl Cancer Inst. 2007;99(17):1304-1312. (Pubitemid 47394169)
4. Lee JS, Spiegel D, Kim SB, Lee JH, Kim SI, Yang BH, Choi JH, Kho YC, Nam JH. Fractal analysis of EEG in hypnosis and its relationship with hypnotizability. Int J Clin Exp Hypn. 2007;55(1):14-31. (Pubitemid 44885066)
5. Colgan SM, Faragher EB, Whorwell PJ. Controlled trial of hypnotherapy in relapse prevention of duodenal ulceration. Lancet. 1988;1(8598):1299-1300.
6. Spiegel D, Bierre P, Rootenberg J. Hypnotic alteration of somatosensory perception. Am J Psychiatry. 1989;146(6):749-754. (Pubitemid 19149586)
7. Rainville P, Hofbauer RK, Paus T, Duncan GH, Bushnell MC, Price DD. Cerebral mechanisms of hypnotic induction and suggestion. J Cogn Neurosci. 1999;11(1):110-125. (Pubitemid 29224573)
8. Faymonville ME, Laureys S, Degueldre C, DelFiore G, Luxen A, Franck G, Lamy M, Maquet P. Neural mechanisms of antinociceptive effects of hypnosis. Anesthesiology. 2000;92(5):1257-1267. (Pubitemid 30257184)
9. Rainville P, Hofbauer RK, Bushnell MC, Duncan GH, Price DD. Hypnosis modulates activity in brain structures involved in the regulation of consciousness. J Cogn Neurosci. 2002;14(6):887-901.
10. Kosslyn SM, Thompson WL, Costantini-Ferrando MF, Alpert NM, Spiegel D. Hypnotic visual illusion alters color processing in the brain. Am J Psychiatry. 2000;157(8):1279-1284. (Pubitemid 30659811)
11. Raz A. Attention and hypnosis: neural substrates and genetic associations of two converging processes. Int J Clin Exp Hypn. 2005;53(3):237-258. (Pubitemid 40967274)
12. Raz A, Fan J, Posner MI. Hypnotic suggestion reduces conflict in the human brain. Proc Natl Acad Sci U S A. 2005;102(28):9978-9983. (Pubitemid 40993678)
13. Raz A, Shapiro T, Fan J, Posner MI. Hypnotic suggestion and the modulation of Stroop interference. Arch Gen Psychiatry. 2002;59(12):1155-1161. (Pubitemid 35424026)
14. Morishima Y, Okuda J, Sakai K. Reactive mechanism of cognitive control system. Cereb Cortex. 2010;20(11):2675-2683.
15. Iani C, Ricci F, Baroni G, Rubichi S. Attention control and susceptibility to hypnosis. Conscious Cogn. 2009;18(4):856-863.
16. Piccione C, Hilgard ER, Zimbardo PG. On the degree of stability of measured hypnotizability over a 25-year period. J Pers Soc Psychol. 1989;56(2):289-295.
17. Tellegen A, Atkinson G. Openness to absorbing and self-altering experiences ("absorption"), a trait related to hypnotic susceptibility. J Abnorm Psychol. 1974;83(3):268-277.
18. Lichtenberg P, Bachner-Melman R, Ebstein RP, Crawford HJ. Hypnotic susceptibility: multidimensional relationships with Cloninger's Tridimensional Personality Questionnaire, COMT polymorphisms, absorption, and attentional characteristics. Int J Clin Exp Hypn. 2004;52(1):47-72. (Pubitemid 38116728)
19. Karlin RA. Hypnotizability and attention. J Abnorm Psychol. 1979;88(1):92-95. (Pubitemid 9131524)
20. Pochon JB, Riis J, Sanfey AG, Nystrom LE, Cohen JD. Functional imaging of decision conflict. J Neurosci. 2008;28(13):3468-3473. (Pubitemid 351469327)
21. Spiegel D, King R. Hypnotizability and CSF HVA levels among psychiatric patients. Biol Psychiatry. 1992;31(1):95-98.
22. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9(1):97-113.
23. Szechtman H, Woody E, Bowers KS, Nahmias C. Where the imaginal appears real: a positron emission tomography study of auditory hallucinations. Proc Natl Acad Sci U S A. 1998;95(4):1956-1960. (Pubitemid 28103501)
24. Maquet P, Faymonville ME, Degueldre C, Delfiore G, Franck G, Luxen A, Lamy M. Functional neuroanatomy of hypnotic state. Biol Psychiatry. 1999;45(3):327-333. (Pubitemid 29100039)
25. Derbyshire SW, Whalley MG, Stenger VA, Oakley DA. Cerebral activation during hypnotically induced and imagined pain. Neuroimage. 2004;23(1):392-401. (Pubitemid 39119470)
26. Schulz-Stübner S, Krings T, Meister IG, Rex S, Thron A, Rossaint R. Clinical hypnosis modulates functional magnetic resonance imaging signal intensities and pain perception in a thermal stimulation paradigm. Reg Anesth Pain Med. 2004;29(6):549-556. (Pubitemid 40039992)
27. Egner T, Jamieson G, Gruzelier J. Hypnosis decouples cognitive control from conflict monitoring processes of the frontal lobe. Neuroimage. 2005;27(4):969-978. (Pubitemid 41317264)
28. Raij TT, Numminen J, Närvänen S, Hiltunen J, Hari R. Brain correlates of subjective reality of physically and psychologically induced pain. Proc Natl Acad Sci U S A. 2005;102(6):2147-2151. (Pubitemid 40262026)
29. McGeown WJ, Mazzoni G, Venneri A, Kirsch I. Hypnotic induction decreases anterior default mode activity. Conscious Cogn. 2009;18(4):848-855.
30. Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe S, Dogonowski AM, Ernst M, Fair D, Hampson M, Hoptman MJ, Hyde JS, Kiviniemi VJ, Kotter R, Li SJ, Lin CP, Lowe MJ, Mackay C, Madden DJ, Madsen KH, Margulies DS, Mayberg HS, McMahon K, Monk CS, Mostofsky SH, Nagel BJ, Pekar JJ, Peltier SJ, Petersen SE, Riedl V, Rombouts SA, Rypma B, Schlaggar BL, Schmidt S, Seidler RD, Siegle GJ, Sorg C, Teng GJ, Veijola J, Villringer A, Walter M, Wang L, Weng XC, Whitfield-Gabrieli S, Williamson P, Windischberger C, Zang YF, Zhang HY, Castellanos FX, Milham MP. Toward discovery science of human brain function. Proc Natl Acad Sci U S A. 2010;107(10):4734- 4739.
31. Van Dijk KR, Hedden T, Venkataraman A, Evans KC, Lazar SW, Buckner RL. Intrinsic functional connectivity as a tool for human conectomics: theory, properties, and optimization. J Neurophysiol. 2010;103(1):297-321.
32. Fox MD, Raichle ME. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci. 2007;8(9):700-711. (Pubitemid 47283145)
33. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL. A default mode of brain function. Proc Natl Acad Sci U S A. 2001;98(2):676-682. (Pubitemid 32105102)
34. Raichle ME. The brain's dark energy. Sci Am. 2010;302(3):44-49.
35. Greicius MD, Srivastava G, Reiss AL, Menon V. Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRI. Proc Natl Acad Sci U S A. 2004;101(13):4637-4642. (Pubitemid 38437463)
36. Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD. Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci. 2007;27(9):2349-2356. (Pubitemid 46340968)
37. Sridharan D, Levitin DJ, Menon V. A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks. Proc Natl Acad Sci U S A. 2008;105(34):12569-12574.
38. Greicius MD, Krasnow B, Reiss AL, Menon V. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci U S A. 2003;100(1):253-258. (Pubitemid 36078061)
39. Buckner RL, Snyder AZ, Shannon BJ, LaRossa G, Sachs R, Fotenos AF, Sheline YI, Klunk WE, Mathis CA, Morris JC, Mintun MA. Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory. J Neurosci. 2005;25(34):7709-7717. (Pubitemid 41208641)
40. Habas C, Kamdar N, Nguyen D, Prater K, Beckmann CF, Menon V, Greicius MD. Distinct cerebellar contributions to intrinsic connectivity networks. J Neurosci. 2009;29(26):8586-8594.
41. Spiegel H, Spiegel D. Trance and Treatment: Clinical Uses of Hypnosis. Washington, DC: American Psychiatric Publishing; 2004.
42. Glover GH, Lai S. Self-navigated spiral fMRI: interleaved versus single-shot. Magn Reson Med. 1998;39(3):361-368. (Pubitemid 28128378)
43. Poline JB, Worsley KJ, Evans AC, Friston KJ. Combining spatial extent and peak intensity to test for activations in functional imaging. Neuroimage. 1997;5(2):83-96. (Pubitemid 27481515)
44. Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed. Hillsdale, NJ: Erlbaum; 1988.
45. Talairach J, Tournoux P. Co-planar Stereotaxic Atlas of the Human Brain. New York, NY: Thieme; 1988.
46. Whitfield-Gabrieli S, Thermenos HW, Milanovic S, Tsuang MT, Faraone SV, McCarley RW, Shenton ME, Green AI, Nieto-Castanon A, LaViolette P, Wojcik J, Gabrieli JD, Seidman LJ. Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc Natl Acad Sci U S A. 2009;106(4):1279-1284.
47. Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage. 2001;14(1, pt 1):21-36. (Pubitemid 32552740)
48. Basser PJ, Mattiello J, LeBihan D. MR diffusion tensor spectroscopy and imaging. Biophys J. 1994;66(1):259-267. (Pubitemid 24016507)
49. Woods RP, Grafton ST, Watson JD, Sicotte NL, Mazziotta JC. Automated image registration, II: intersubject validation of linear and nonlinear models. J Comput Assist Tomogr. 1998;22(1):153-165. (Pubitemid 28087338)
50. Jiang H, van Zijl PC, Kim J, Pearlson GD, Mori S. DtiStudio: resource program for diffusion tensor computation and fiber bundle tracking. Comput Methods Programs Biomed. 2006;81(2):106-116. (Pubitemid 43144442)
51. Mori S, Kaufmann WE, Davatzikos C, Stieltjes B, Amodei L, Fredericksen K, Pearlson GD, Melhem ER, Solaiyappan M, Raymond GV, Moser HW, van Zijl PC. Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking. Magn Reson Med. 2002;47(2):215-223. (Pubitemid 34116788)
52. Mori S, Crain BJ, Chacko VP, van Zijl PC. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol. 1999;45(2):265-269. (Pubitemid 29072377)
53. Williamson JW, McColl R, Mathews D, Mitchell JH, Raven PB, Morgan WP. Brain activation by central command during actual and imagined handgrip under hypnosis. J Appl Physiol. 2002;92(3):1317-1324. (Pubitemid 34670994)
54. Rainville P, Duncan GH, Price DD, Carrier B, Bushnell MC. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science. 1997;277(5328):968-971. (Pubitemid 27366684)
55. Vanhaudenhuyse A, Boly M, Balteau E, Schnakers C, Moonen G, Luxen A, Lamy M, Degueldre C, Brichant JF, Maquet P, Laureys S, Faymonville ME. Pain and non-pain processing during hypnosis: a thulium-YAG event-related fMRI study. Neuroimage. 2009;47(3):1047-1054.
56. Posner MI, Petersen SE. The attention system of the human brain. Annu Rev Neurosci. 1990;13:25-42. (Pubitemid 20100639)
57. Frischholz EJ, Spiegel D, Trentalange MJ, Spiegel H. The Hypnotic Induction Profile and absorption. Am J Clin Hypn. 1987;30(2):87-93.
58. Kihlstrom JF, Register PA, Hoyt IP, Albright JS, Grigorian EM, Heindel WC, Morrison CR. Dispositional correlates of hypnosis: a phenomenological approach. Int J Clin Exp Hypn. 1989;37(3):249-263. (Pubitemid 19182797)
59. Bowers P. Hypnotizability, creativity and the role of effortless experiencing. Int J Clin Exp Hypn. 1978;26(3):184-202. (Pubitemid 9017634)
60. Goldberg TE, Weinberger DR. Genes and the parsing of cognitive processes. Trends Cogn Sci. 2004;8(7):325-335. (Pubitemid 38887449)
61. Lichtenberg P, Bachner-Melman R, Gritsenko I, Ebstein RP. Exploratory association study between catechol-O-methyltransferase (COMT) high/low enzyme activity polymorphism and hypnotizability. Am J Med Genet. 2000;96(6):771-774.
62. Szekely A, Kovacs-Nagy R, Bányai EI, Gosi-Greguss AC, Varga K, Halmai Z, Ronai Z, Sasvari-Szekely M. Association between hypnotizability and the catechol-O-methyltransferase (COMT) polymorphism. Int J Clin Exp Hypn. 2010;58(3):301-315.
63. Spiegel D. Intelligent design or designed intelligence? Hypnotizability as neurobiological adaptation. In: Nash MR, Barnier AJ, eds. The Oxford Handbook of Hypnosis: Theory, Research and Practice. New York, NY: Oxford University Press; 2008:179-199.
64. Spiegel H, Aronson M, Fleiss JL, Haber J. Psychometric analysis of the Hypnotic Induction Profile. Int J Clin Exp Hypn. 1976;24(3):300-315.
65. Stern DB, Spiegel H, Nee JC. The Hypnotic Induction Profile: normative observations, reliability and validity. Am J Clin Hypn. 1978;21(2-3):109-133.
66. Spiegel D, Detrick D, Frischholz E. Hypnotizability and psychopathology. Am J Psychiatry. 1982;139(4):431-437. (Pubitemid 12141034)
67. Orne MT, Hilgard ER, Spiegel H, Spiegel D, Crawford HJ, Evans FJ, Orne EC, Frischholz EJ. The relation between the Hypnotic Induction Profile and the Stanford Hypnotic Susceptibility Scales, forms A and C. Int J Clin Exp Hypn. 1979;27(2):85-102. (Pubitemid 9230368)
68. Frischholz EJ, Tryon WW, Fisher S, Maruffi BL, Vellios AT, Spiegel H. The relationship between the Hypnotic Induction Profile and the Stanford Hypnotic Susceptibility Scale, Form C: a replication. Am J Clin Hypn. 1980;22(4):185-196. (Pubitemid 11252427)
69. Frishholz EJ, Spiegel H, Tryon WW, Fisher S. The relationship between the Hypnotic Induction Profile and the Stanford Hypnotic Susceptibility Scale, Form C: revisited. Am J Clin Hypn. 1981;24(2):98-105. (Pubitemid 12121137)
70. Du Hamel KN, Difede J, Foley F, Greenleaf M. Hypnotizability and trauma symptoms after burn injury. Int J Clin Exp Hypn. 2002;50(1):33-50. (Pubitemid 33152123)
71. Keuroghlian AS, Butler LD, Neri E, Spiegel D. Hypnotizability, posttraumatic stress, and depressive symptoms in metastatic breast cancer. Int J Clin Exp Hypn. 2010;58(1):39-52.
72. Spiegel D, Hunt T, Dondershine HE. Dissociation and hypnotizability in posttraumatic stress disorder. Am J Psychiatry. 1988;145(3):301-305. (Pubitemid 18078308)
73. Barry JJ, Atzman O, Morrell MJ. Discriminating between epileptic and nonepileptic events: the utility of hypnotic seizure induction. Epilepsia. 2000;41(1):81-84. (Pubitemid 30036859)
74. Pettinati HM, Kogan LG, Evans FJ, Wade JH, Horne RL, Staats JM. Hypnotizability of psychiatric inpatients according to two different scales. Am J Psychiatry. 1990;147(1):69-75. (Pubitemid 20025509)
75. Frischholz EJ, Lipman LS, Braun BG, Sachs RG. Psychopathology, hypnotizability, and dissociation. Am J Psychiatry. 1992;149(11):1521-1525.
76. Spiegel D, Frischholz EJ, Fleiss JL, Spiegel H. Predictors of smoking abstinence following a single-session restructuring intervention with self-hypnosis. Am J Psychiatry. 1993;150(7):1090-1097. (Pubitemid 23198630)
77. Spiegel D, Frischholz EJ, Maruffi B, Spiegel H. Hypnotic responsitivity and the treatment of flying phobia. Am J Clin Hypn. 1981;23(4):239-247. (Pubitemid 12246360)
78. Kosslyn SM, Cacioppo JT, Davidson RJ, Hugdahl K, Lovallo WR, Spiegel D, Rose R. Bridging psychology and biology: the analysis of individuals in groups. Am Psychol. 2002;57(5):341-351.
79. Ersche KD, Turton AJ, Pradhan S, Bullmore ET, Robbins TW. Drug addiction endophenotypes: impulsive versus sensation-seeking personality traits. Biol Psychiatry. 2010;68(8):770-773.
80. Canli T, Sivers H, Whitfield SL, Gotlib IH, Gabrieli JD. Amygdala response to happy faces as a function of extraversion. Science. 2002;296(5576):2191. doi:10.1126/science.1068749. (Pubitemid 34680296)
81. Davidson RJ. Empirical explorations of mindfulness: conceptual and methodological conundrums. Emotion. 2010;10(1):8-11.
82. Davidson RJ, Kabat-Zinn J, Schumacher J, Rosenkranz M, Muller D, Santorelli SF, Urbanowski F, Harrington A, Bonus K, Sheridan JF. Alterations in brain and immune function produced by mindfulness meditation. Psychosom Med. 2003;65(4):564-570. (Pubitemid 36900251)