Lectin histochemistry to detect altered glycosylation in cells and tissues

Methods in Molecular Biology

Volumn 878, Issue , 2012, Pages 31-50

  Brooks, Susan A ^a   Hall, Debbie M S ^a  

^a OXFORD BROOKES UNIVERSITY   (United Kingdom)

Author keywords

Direct; FFPE tissue; Frozen; Glycan; Histochemistry; Indirect; Lectin

Indexed keywords

CARBOHYDRATE; LECTIN; MONOSACCHARIDE; N ACETYLGLUCOSAMINE; OLIGOSACCHARIDE; PEROXIDASE; PHYTOHEMAGGLUTININ; SIALIC ACID DERIVATIVE; SILANE; PARAFFIN; TRYPSIN;

ARTICLE; BINDING AFFINITY; CARBOHYDRATE ANALYSIS; CELL CULTURE; GLYCOSYLATION; HISTOCHEMISTRY; HUMAN; LECTIN BINDING; METASTASIS; NOMENCLATURE; PRIORITY JOURNAL; SIALYLATION; SYNTHESIS; TISSUE PREPARATION; ANIMAL; CYTOCHEMISTRY; FROZEN SECTION; HEAT; METABOLISM; METHODOLOGY; STAINING; TISSUE FIXATION;

ANIMALS; FROZEN SECTIONS; GLYCOSYLATION; HISTOCYTOCHEMISTRY; HOT TEMPERATURE; HUMANS; LECTINS; PARAFFIN EMBEDDING; PEROXIDASE; STAINING AND LABELING; TISSUE FIXATION; TRYPSIN;

EID: 84867036650     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-854-2_2     Document Type: Article

References (17)

1. Goldstein IJ, Hughes RC, Monsigny M, Osawa T, Sharon N (1980) What should be called a lectin?. Nature 285:66
2. Brooks SA, Carter TM, Royle L, Harvey DJ, Fry SA, Kinch C, Dwek RA, Rudd PM (2008) Altered glycosylation of proteins in cancer: what is the potential for new anti-tumour strategies. Anticancer Agents Med Chem 8:2-21
3. Dwek MV, Brooks SA (2004) Harnessing changes in cellular glycosylation in new cancer treatment strategies. Curr Cancer Drug Targets 4:425-442
4. Hakomori S (2001) Tumor-associated carbohydrate antigens de fi ning tumor malignancy: basis for development of anti-cancer vaccines. Adv Exp Med Biol 491:369-402
5. Maramatsu T (1993) Carbohydrate signals in metastasis and prognosis of human carcinomas. Glycobiology 3:294-296
6. Kanangi R (1997) Carbohydrate mediated cell adhesion involved in hematogenous metastasis of cancer. Glycoconj J 14:577-584
7. Renkonen R, Mattila P, Marja-Leena M, Rabina J, Toppila S, Renkonen J, Hirvas L, Niittymaki J, Turunen JP, Renkonen O, Paavonen T (1997) In vitro experimental studies of sialyl Lewis x and sialyl Lewis a on endothelial and carcinoma cells: crucial glycans on selectin ligands. Glycoconj J 14: 593-600
8. Nakano T, Matsui T, Ota T (1996) Benzylalpha-GalNAc inhibits sialylation of O-glycosidic sugar chains and enhances experimental metastatic capacity in B16BL6 melanoma cells. Anticancer Res 16:3577-3584
9. Yogeeswaren G, Salk PL (1981) Metastatic potential is positively correlated with cell surface sialylation of cultured murine tumor cells. Science 212:1514-1516
10. Dennis JW, Laferte S, Waghorne C, Breitman ML, Kerbel RS (1987) Beta 1-6 branching Asn-linked oligosaccharides is directly associated with metastasis. Science 236:582-585
11. Fernandes B, Sagman U, Auger M, Demetrio M, Dennis JW (1991) Beta 1-6 branched oligosaccharides as a marker of tumor progression in human breast and colon neoplasia. Cancer Res 51:718-723
12. Korczak B, Goss P, Fernandes B, Baker M, Dennis JW (1984) Branching N-linked oligosaccharides in breast cancer. Adv Exp Med Biol 353:95-104
13. Brooks SA, Leathem AJC (1991) Prediction of lymph node involvement in breast cancer by detection of altered glycosylation in the primary tumour. Lancet 338:71-74
14. Schumacher U, Higgs D, Loizidou M, Pickering R, Leathem A, Taylor I (1994) Helix pomatia agglutinin binding is a useful prognostic indicator in colorectal carcinoma. Cancer 74:3104-3107
15. Kakeji Y, Maehara Y, Tsujitani S, Baba H, Ohno S, Watanabe A, Sugimachi K (1994) Helix pomatia agglutinin binding activity and lymph node metastasis in patients with gastric cancer. Semin Surg Oncol 10:130-134
16. Yoshida Y, Okamura T, Shirakusa T (1994) An immunohistochemical study of Helix pomatia agglutinin binding on carcinomas of the esophagus. Surg Gynecol Obstet 177: 299-302
17. Brooks SA, Lymboura M, Schumacher U, Leathem AJC (1996) Helix pomatia lectin binding in breast cancer-methodology makes a difference. J Histochem Cytochem 44: 519-524