Implanted electro-acupuncture electric stimulation improves outcome of stem cells' transplantation in spinal cord injury

Artificial Cells, Blood Substitutes, and Biotechnology

Volumn 40, Issue 5, 2012, Pages 331-337

  Liu, Haichun ^a   Yang, Kaiyun ^a   Xin, Tao ^b   Wu, Wenliang ^a   Chen, Yunzhen ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Bone marrow derived mesenchymal cells (BMSCs); Electro acupuncture; Mesenchymal stem cells; Spinal cord injury

Indexed keywords

BENEFICIAL EFFECTS; DIFFERENTIATION RATE; ELECTRIC STIMULATION; ELECTRICAL STIMULATIONS; FUNCTIONAL RECOVERY; INJURED SPINAL CORDS; LOCOMOTOR FUNCTION; MESENCHYMAL CELLS; MESENCHYMAL STEM CELL; MESENCHYMAL STROMAL CELLS; SPINAL CORD INJURIES (SCI); SPINAL CORDS; SURVIVAL RATE; TRANSPLANTED CELLS;

ANIMALS; BONE; CELL CULTURE; ELECTROACUPUNCTURE; ELECTROPHYSIOLOGY; MOLECULAR BIOLOGY; STEM CELLS; STIMULATED EMISSION;

PATIENT REHABILITATION;

ACUPUNCTURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; COMPLICATION; CONTROLLED STUDY; DEATH; ELECTROSTIMULATION; FORELIMB; FUNCTIONAL STATUS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATURIA; HINDLIMB; HISTOLOGY; INFECTION; LIMB SWELLING; LIMB ULCER; LOCOMOTION; MALE; MOLECULAR BIOLOGY; MOTOR COORDINATION; MOTOR PERFORMANCE; NONHUMAN; RAT; SENSORY SYSTEM ELECTROPHYSIOLOGY; SPINAL CORD INJURY; UROSCHESIS;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; ELECTRIC STIMULATION THERAPY; ELECTROACUPUNCTURE; ELECTRODES, IMPLANTED; HUMANS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SPINAL CORD INJURIES;

ANIMALIA;

EID: 84867009868     PISSN: 10731199     EISSN: 15324184     Source Type: Journal    
DOI: 10.3109/10731199.2012.659350     Document Type: Article

References (23)

1. Ariza CA, Fleury AT, Tormos CJ, Petruk V, Chawla S, Oh J, Sakaguchi DS, Mallapragada SK. 2010. Th e infl uence of electric fi elds on hippocampal neural progenitor cells. Stem Cell Rev. 6(4):585-600.
2. Basso DM, Beattie MS, Bresnahan JC. 1995. A sensitive and reliable locomotor rating scale for open fi eld testing in rats. J Neurotrauma. 12(1):1-21.
3. Caplan AI. 2007. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J Cell Physiol. 213:341-347. (Pubitemid 47509711)
4. Choi CB, Cho YK, Prakash KV, Jee BK, Han CW, Paik YK, Kim HY, Lee KH, Chung N, Rha HK. 2006. Analysis of neuron-like diff erentiation of human bone marrow mesenchymal stem cells. Biochem Biophys Res Commun. 350:138-146. (Pubitemid 44466583)
5. Cho JS, Park HW, Park SK, Roh S, Kang SK, Paik KS, Chang MS. 2009. Transplantation of mesenchymal stem cells enhances axonal outgrowth and cell survival in an organotypic spinal cord slice culture. Neurosci Lett. 454:43-48.
6. Ding Y, Yan Q, Ruan JW, Zhang YQ, Li WJ, Zeng X, Huang SF, Zhang YJ, Wang S, Dong H, Zeng YS. 2010. Bone marrow mesenchymal stem cells and electro-acupuncture downregulate the inhibitor molecules and promote the axonal regeneration in the transected spinal cord of rats. Cell Transplant. 20(4):475-491.
7. Ding Y, Yan Q, Ruan JW, Zhang YQ, Li WJ, Zhang YJ, Li Y, Dong H, Zeng YS. 2009. Electro-acupuncture promotes survival, diff erentiation of the bone marrow mesenchymal stem cells as well as functional recovery in the spinal cord-transected rats. BMC Neurosci. 10:35.
8. Dorsher PT, McIntosh PM. 2009. Acupuncture's eff ects in treating the sequelae of acute and chronic spinal cord injuries: A review of allopathic and traditional Chinese medicine literature. Evid Based Complement Alternat Med. 2011: 428108.
9. Fitch MT, Silver J. 2009. CNS injury, glial scars, and infl ammation: Inhibitory extracellular matrices and regeneration failure. Exp Neurol. 209:294-301. (Pubitemid 351174127)
10. Hyodo M, Kitade T. 1979. A guide to silver spike point (SSP) therapy, 2nd ed.; Tokyo: Th e Silver Spike Point Th erapy Study Group.
11. Miller RH, Bai L, Lennon DP, Caplan AI. 2010. Th e potential of mesenchymal stem cells for neural repair. Discov Med. 46:236-242.
12. Parr AM, Tator CH, Keating A. 2007. Bone marrow-derived mesenchymal stromal cells for the repair of central nervous system injury. Bone Marrow Transplant. 40:609-619. (Pubitemid 47456475)
13. Satake K, Lou J, Lenke LG. 2004. Migration of mesenchymal stem cells through cerebrospinal fl uid into injured spinal cord tissue. Spine 29:1971-1979. (Pubitemid 40202267)
14. Shapiro S, Borgens R, Pascuzzi R, Roos K, Groff M, Purvines S, Rodgers RB, Hagy S, Nelson P. 2005. Oscillating fi eld stimulation for complete spinal cord injury in humans: A phase 1 trial. J Neurosurg Spine. 2:3-10.
15. Sundelacruz S, Levin M, Kaplan DL. 2009. Membrane potential controls adipogenic and osteogenic diff erentiation of mesenchymal stem cells. PLoS One. 3:e3737.
16. Sun Z, Li X, Su Z, Zhao Y, Zhang L, Wu M. 2009. Electroacupunctureenhanced diff erentiation of bone marrow stromal cells into neuronal cells. J Sport Rehabil. 18:398-406.
17. Th uret S, Moon LD, Gage FH. 2006. Th erapeutic interventions after spinal cord injury. Nat Rev Neurosci. 7:628-643. (Pubitemid 44106745)
18. Tseng KL, Liu HJ, Tso KY, et al. 2006. A clinical study of acupuncture and SSP (silver spike point) electro-therapy for dry eye syndrome. Am J Chin Med. 34:197-206.
19. Wong AM, Leong CP, Su TY, Yu SW, Tsai WC, Chen CP. 2003. Clinical trial of acupuncture for patients with spinal cord injuries. Am J Phys Med Rehabil. 82(1):21-27. (Pubitemid 36043759)
20. Wright KT, Masri WE, Osman A, Roberts S, Trivedi J, Ashton BA, Johnson WE. 2008. Th e cell culture expansion of bone marrow stromal cells from humans with spinal cord injury: Implications for future cell transplantation therapy. Spinal Cord. 46:811-817.
21. Wu WL, Zhao H, Xie B, Liu HC, Chen YZ, Jiao GJ, Wang HL. 2011. Implanted spike wave electric stimulation promotes survival of the bone marrow mesenchymal stem cells and functional recovery in the spinal cord injured rats. Neurosci Lett. 491 (4):73-78.
22. Yan Q, Ruan JW, Ding Y, Li WJ, Li Y, Zeng YS. 2011. Electroacupuncture promotes diff erentiation of mesenchymal stem cells, regeneration of nerve fi bers and partial functional recovery after spinal cord injury. Exp Toxicol Pathol. 63(1-2):151-156.
23. Yoon SH, Shim YS, Park YH, Chung JK, Nam JH, Kim MO, Park HC, Park SR, Min BH, Kim EY, Choi BH, Park H, Ha Y. 2007. Complete spinal cord injury treatment using autologous bone marrow cell transplantation and bone marrow stimulation with granulocyte macrophage-colony stimulating factor: Phase I/II clinical trial. Stem Cells. 25:2066-2073. (Pubitemid 47258184)