Extraskeletal myxoid chondrosarcoma: A review of 23 patients treated at a single referral center with long-term follow-up

Archives of Orthopaedic and Trauma Surgery

Volumn 132, Issue 10, 2012, Pages 1379-1386

  Ogura, Koichi ^a,b   Fujiwara, Tomohiro ^a   Beppu, Yasuo ^a   Chuman, Hirokazu ^a   Yoshida, Akihiko ^a   Kawano, Hirotaka ^b   Kawai, Akira ^a  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b UNIVERSITY OF TOKYO HOSPITAL   (Japan)

Author keywords

Chemotherapy; Extraskeletal myxoid chondrosarcoma; Radiotherapy; Surgery

Indexed keywords

CISPLATIN; DACARBAZINE; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CANCER SURGERY; CHONDROSARCOMA; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; FOLLOW UP; HUMAN; LOCAL RECURRENCE FREE SURVIVAL; MALE; METASTASIS; METASTASIS FREE SURVIVAL; MYXOID CHONDROSARCOMA; OVERALL SURVIVAL; PRIMARY TUMOR; PRIORITY JOURNAL; PROGNOSIS; RETROSPECTIVE STUDY; SURVIVAL RATE; TUMOR VOLUME;

ADULT; AGED; CHONDROSARCOMA; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM RECURRENCE, LOCAL; RETROSPECTIVE STUDIES; SARCOMA; SURVIVAL ANALYSIS;

EID: 84866984004     PISSN: 09368051     EISSN: 14343916     Source Type: Journal    
DOI: 10.1007/s00402-012-1557-9     Document Type: Article

References (23)

1. Enzinger FM, Shiraki M (1972) Extraskeletal myxoid chondrosarcoma. An analysis of 34 cases. Hum Pathol 3(3):421-435
2. Hisaoka M, Hashimoto H (2005) Extraskeletal myxoid chondrosarcoma: updated clinicopathological and molecular genetic characteristics. Pathol Int 55(8):453-463. doi:10.1111/j.1440- 1827.2005.01853.x
3. Lucas DR, Fletcher CD, Adsay NV, Zalupski MM (1999) Highgrade extraskeletal myxoid chondrosarcoma: a high-grade epithelioid malignancy. Histopathology 35(3):201-208 (pii: his735)
4. Meis-Kindblom JM, Bergh P, Gunterberg B, Kindblom LG (1999) Extraskeletal myxoid chondrosarcoma: a reappraisal of its morphologic spectrum and prognostic factors based on 117 cases. Am J Surg Pathol 23(6):636-650
5. Fletcher CDM, Unni KK, Mertens F (2002) World Health Organization Classification of Tumours. Pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon
6. Drilon AD, Popat S, Bhuchar G, D'Adamo DR, Keohan ML, Fisher C, Antonescu CR, Singer S, Brennan MF, Judson I, Maki RG (2008) Extraskeletal myxoid chondrosarcoma: a retrospective review from 2 referral centers emphasizing long-term outcomes with surgery and chemotherapy. Cancer 113(12):3364-3371. doi: 10.1002/cncr.23978
7. McGrory JE, Rock MG, Nascimento AG, Oliveira AM (2001) Extraskeletal myxoid chondrosarcoma. Clin Orthop Relat Res 382:185-190
8. Oliveira AM, Sebo TJ, McGrory JE, Gaffey TA, Rock MG, Nascimento AG (2000) Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and ploidy analysis of 23 cases. Mod Pathol 13(8):900-908. doi:10.1038/modpathol. 3880161
9. Kawaguchi S, Wada T, Nagoya S, Ikeda T, Isu K, Yamashiro K, Kawai A, Ishii T, Araki N, Myoui A, Matsumoto S, Umeda T, Yoshikawa H, Hasegawa T (2003) Extraskeletal myxoid chondrosarcoma: a Multi-Institutional Study of 42 Cases in Japan. Cancer 97(5):1285-1292. doi:10.1002/cncr.11162
10. Okamoto S, Hisaoka M, Ishida T, Imamura T, Kanda H, Shimajiri S, Hashimoto H (2001) Extraskeletal myxoid chondrosarcoma: a clinicopathologic, immunohistochemical, and molecular analysis of 18 cases. Hum Pathol 32(10):1116-1124. doi:10.1053/hupa.2001.28226
11. Saleh G, Evans HL, Ro JY, Ayala AG (1992) Extraskeletal myxoid chondrosarcoma. A clinicopathologic study of ten patients with long-term follow-up. Cancer 70(12):2827-2830
12. Tsuneyoshi M, Enjoji M, Iwasaki H, Shinohara N (1981) Extraskeletal myxoid chondrosarcoma-a clinicopathologic and electron microscopic study. Acta Pathol Jpn 31(3):439-447
13. Hasegawa T, Yamamoto S, Nojima T, Hirose T, Nikaido T, Yamashiro K, Matsuno Y (2002) Validity and reproducibility of histologic diagnosis and grading for adult soft-tissue sarcomas. Hum Pathol 33(1):111-115 (pii:S0046817702212800)
14. Liu CY, Yen CC, Chen WM, Chen TH, Chen PC, Wu HT, Shiau CY, Wu YC, Liu CL, Tzeng CH (2010) Soft tissue sarcoma of extremities: the prognostic significance of adequate surgical margins in primary operation and reoperation after recurrence. Ann Surg Oncol 17(8):2102-2111. doi:10.1245/s10434-010- 0997-0
15. Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, Dancey J, Arbuck S, Gwyther S, Mooney M, Rubinstein L, Shankar L, Dodd L, Kaplan R, Lacombe D, Verweij J (2009) New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 45(2):228-247. doi: 10.1016/j.ejca.2008.10.026
16. Aigner T, Oliveira AM, Nascimento AG (2004) Extraskeletal myxoid chondrosarcomas do not show a chondrocytic phenotype. Mod Pathol 17(2):214-221. doi:10.1038/modpathol.3800036
17. Downs-Kelly E, Goldblum JR, Patel RM, Weiss SW, Folpe AL, Mertens F, Hartke M, Tubbs RR, Skacel M (2008) The utility of fluorescence in situ hybridization (FISH) in the diagnosis of myxoid soft tissue neoplasms. Am J Surg Pathol 32(1):8-13. doi: 10.1097/PAS.0b013e3181578d5a
18. Maltais A, Filion C, Labelle Y (2002) The AF2 domain of the orphan nuclear receptor TEC is essential for the transcriptional activity of the oncogenic fusion protein EWS/TEC. Cancer Lett 183(1):87-94 (pii: S0304383502001040)
19. Labelle Y, Bussieres J, Courjal F, Goldring MB (1999) The EWS/TEC fusion protein encoded by the t(9;22) chromosomal translocation in human chondrosarcomas is a highly potent transcriptional activator. Oncogene 18(21):3303-3308. doi:10.1038/sj.onc.1202675
20. Ohkura N, Yaguchi H, Tsukada T, Yamaguchi K (2002) The EWS/NOR1 fusion gene product gains a novel activity affecting pre-mRNA splicing. J Biol Chem 277(1):535-543. doi:10.1074/jbc.M109018200
21. Wang WL, Mayordomo E, Czerniak BA, Abruzzo LV, Dal Cin P, Araujo DM, Lev DC, Lopez-Terrada D, Lazar AJ (2008) Fluorescence in situ hybridization is a useful ancillary diagnostic tool for extraskeletal myxoid chondrosarcoma. Mod Pathol 21(11):1303-1310. doi:10.1038/modpathol.2008.114
22. Patel SR, Burgess MA, Papadopoulos NE, Linke KA, Benjamin RS (1995) Extraskeletal myxoid chondrosarcoma. Long-term experience with chemotherapy. Am J Clin Oncol 18(2):161-163
23. Rubinger M, Plenderleith IH, Lertzman M, Worth AJ (1995) Metastatic extraskeletal myxoid chondrosarcoma. Successful therapy with interferon alfa-2b. Chest 108(1):281-282