Differential expression of NMDA receptors in serotonergic and/or GABAergic neurons in the midbrain periaqueductal gray of the mouse

Neuroscience Letters

Volumn 528, Issue 1, 2012, Pages 55-60

  Terashima, Tetsuji ^a   Shirakawa, Kenshu ^a   Maekawa, Masao ^a   Furukawa, Naoki ^a   Yamaguchi, Shigeki ^a   Hori, Yuuichi ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Excitatory postsynaptic current; GABAergic neurons; Midbrain PAG; Neuropathic pain; NMDA receptor; Serotonergic neurons; Single cell real time RT PCR

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROTRANSMITTER;

ANIMAL CELL; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; MESENCEPHALON; MOUSE; NERVE LIGATION; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PERIPHERAL NERVE INJURY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NERVE; SEROTONINERGIC NERVE CELL; SINGLE CELL ANALYSIS; SYNAPTIC TRANSMISSION;

ANIMALS; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; GABAERGIC NEURONS; LIGATION; MALE; MICE; MICE, INBRED ICR; NEURALGIA; ORGAN CULTURE TECHNIQUES; PATCH-CLAMP TECHNIQUES; PERIAQUEDUCTAL GRAY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, N-METHYL-D-ASPARTATE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCIATIC NERVE; SEROTONERGIC NEURONS;

EID: 84866953898     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.08.061     Document Type: Article

References (29)

1. Albin R.L., Makowiec R.L., Hollingsworth Z., Dure L.S.T., Penney J.B., Young A.B. Excitatory amino acid binding sites in the periaqueductal gray of the rat. Neuroscience Letters 1990, 118:112-115.
2. Behbehani M.M. Functional characteristics of the midbrain periaqueductal gray. Progress in Neurobiology 1995, 46:575-605.
3. Beitz A.J., Shepard R.D., Wells W.E. The periaqueductal gray-raphe magnus projection contains somatostatin, neurotensin and serotonin but not cholecystokinin. Brain Research 1983, 261:132-137.
4. Berrino L., Oliva P., Rossi F., Palazzo E., Nobili B., Maione S. Interaction between metabotropic and NMDA glutamate receptors in the periaqueductal grey pain modulatory system. Naunyn-Schmiedeberg's Archives of Pharmacology 2001, 364:437-443.
5. Cull-Candy S., Brickley S., Farrant M. NMDA receptor subunits: diversity, development and disease. Current Opinion in Neurobiology 2001, 11:327-335.
6. D'Amico M., Berrino L., Maione S., Filippelli A., de Novellis V., Rossi F. Endothelin-1 in periaqueductal gray area of mice induces analgesia via glutamatergic receptors. Pain 1996, 65:205-209.
7. Erreger K., Dravid S.M., Banke T.G., Wyllie D.J., Traynelis S.F. Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles. Journal of Physiology 2005, 563:345-358.
8. Finn D.P., Jhaveri M.D., Beckett S.R., Roe C.H., Kendall D.A., Marsden C.A., Chapman V. Effects of direct periaqueductal grey administration of a cannabinoid receptor agonist on nociceptive and aversive responses in rats. Neuropharmacology 2003, 45:594-604.
9. Flint A.C., Maisch U.S., Weishaupt J.H., Kriegstein A.R., Monyer H. NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex. Journal of Neuroscience 1997, 17:2469-2476.
10. Ghelardini C., Galeotti N., Vivoli E., Norcini M., Zhu W., Stefano G.B., Guarna M., Bianchi E. Molecular interaction in the mouse PAG between NMDA and opioid receptors in morphine-induced acute thermal nociception. Journal of Neurochemistry 2008, 105:91-100.
11. Guo W., Robbins M.T., Wei F., Zou S., Dubner R., Ren K. Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation. Journal of Neuroscience 2006, 26:126-137.
12. Hu J., Wang Z., Guo Y.Y., Zhang X.N., Xu Z.H., Liu S.B., Guo H.J., Yang Q., Zhang F.X., Sun X.L., Zhao M.G. A role of periaqueductal grey NR2B-containing NMDA receptor in mediating persistent inflammatory pain. Molecular Pain 2009, 5:71.
13. Irifune M., Shimizu T., Nomoto M., Fukuda T. Ketamine-induced anesthesia involves the N-methyl-d-aspartate receptor-channel complex in mice. Brain Research 1992, 596:1-9.
14. Lichtman A.H., Cook S.A., Martin B.R. Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement. Journal of Pharmacology and Experimental Therapeutics 1996, 276:585-593.
15. Miguel T.T., Nunes-de-Souza R.L. Defensive-like behaviors and antinociception induced by NMDA injection into the periaqueductal gray of mice depend on nitric oxide synthesis. Brain Research 2006, 1076:42-48.
16. Monyer H., Burnashev N., Laurie D.J., Sakmann B., Seeburg P.H. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 1994, 12:529-540.
17. Reichling D.B. GABAergic neuronal circuitry in the periaqueductal gray matter. The Midbrain Periaqueductal Gray Matter 1991, Plenum, New York. A. Depaulis, R. Bandler (Eds.).
18. Renno W.M. Prolonged noxious stimulation increases periaqueductal gray NMDA mRNA expression: a hybridization study using two different rat models for nociception. Irish Journal of Medical Science 1998, 167:181-192.
19. Sah P., Hestrin S., Nicoll R.A. Tonic activation of NMDA receptors by ambient glutamate enhances excitability of neurons. Science 1989, 246:815-818.
20. Seeburg P.H. The TINS/TiPS lecture. The molecular biology of mammalian glutamate receptor channels. Trends in Neurosciences 1993, 16:359-365.
21. Seltzer Z., Dubner R., Shir Y. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 1990, 43:205-218.
22. Steinbusch H.W. Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. Neuroscience 1981, 6:557-618.
23. Strack A.M., Sawyer W.B., Hughes J.H., Platt K.B., Loewy A.D. A general pattern of CNS innervation of the sympathetic outflow demonstrated by transneuronal pseudorabies viral infections. Brain Research 1989, 491:156-162.
24. Tao R., Auerbach S.B. Regulation of serotonin release by GABA and excitatory amino acids. Journal of Psychopharmacology 2000, 14:100-113.
25. Tolle T.R., Berthele A., Zieglgansberger W., Seeburg P.H., Wisden W. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. Journal of Neuroscience 1993, 13:5009-5028.
26. Tsuchiya M., Yamazaki H., Hori Y. Enkephalinergic neurons express 5-HT3 receptors in the spinal cord dorsal horn: single cell RT-PCR analysis. Neuroreport 1999, 10:2749-2753.
27. Vaccarino A.L., Clemmons H.R., Mader G.J., Magnusson J.E. A role of periaqueductal grey NMDA receptors in mediating formalin-induced pain in the rat. Neuroscience Letters 1997, 236:117-119.
28. Yaksh T.L. Pharmacology and mechanisms of opioid analgesic activity. Acta Anaesthesiologica Scandinavica 1997, 41:94-111.
29. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16:109-110.