Profilin1 regulates sternum development and endochondral bone formation

Journal of Biological Chemistry

Volumn 287, Issue 40, 2012, Pages 33545-33553

  Miyajima, Daisuke ^a   Hayata, Tadayoshi ^a   Suzuki, Takafumi ^a   Hemmi, Hiroaki ^a   Nakamoto, Tetsuya ^a   Notomi, Takuya ^a   Amagasa, Teruo ^a   Böttcher, Ralph T ^b   Costell, Mercedes ^c   Fässler, Reinhard ^b   Ezura, Yoichi ^a   Noda, Masaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c UNIVERSITY OF VALENCIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN CYTOSKELETON; ACTIN FIBERS; ACTIN-BINDING PROTEINS; BONE DEVELOPMENT; BONE FORMATION; CELL MIGRATION; CELL MOTILITY; CELLULAR ACTIVITIES; CORTICAL BONE; CRE RECOMBINASE; CYTOSKELETAL REARRANGEMENTS; DYNAMIC PROCESS; GENETIC ABLATION; IN-VITRO; LONG BONE; LONGITUDINAL GROWTH; MESENCHYMAL PROGENITOR CELLS; MICROENVIRONMENTS; MORPHOLOGICAL ADAPTATIONS; OSTEOBLASTIC CELLS; PROGENITOR CELL; SKELETAL DEVELOPMENT; TRABECULAR BONES;

BONE; CYTOLOGY; MUSCULOSKELETAL SYSTEM; STEM CELLS;

PROTEINS;

CRE RECOMBINASE; PROFILIN; PROFILIN I; PROTEIN PRX1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE DEVELOPMENT; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; ENCHONDRAL OSSIFICATION; GENETIC TRANSFECTION; HISTOLOGY; IN VITRO STUDY; LONG BONE; MESENCHYMAL STEM CELL; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NEWBORN; NONHUMAN; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN FUNCTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STERNUM; STERNUM DEFECT; STERNUM DEVELOPMENT; TRABECULAR BONE;

ALLELES; ANIMALS; BONE AND BONES; CARTILAGE; CELL MOVEMENT; CYTOSKELETON; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; MESENCHYMAL STROMAL CELLS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NIH 3T3 CELLS; OSTEOBLASTS; OSTEOGENESIS; PROFILINS; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION; X-RAY MICROTOMOGRAPHY;

MUS;

EID: 84866933279     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.329938     Document Type: Article

References (36)

1. Karsenty, G., and Wagner, E. F. (2002) Reaching a genetic and molecular understanding of skeletal development. Dev. Cell 2, 389-406 (Pubitemid 34436569)
2. Kronenberg, H. M. (2007) The role of the perichondrium in fetal bone development. Ann. N.Y. Acad. Sci. 1116, 59-64
3. Karsenty, G., Kronenberg, H. M., and Settembre, C. (2009) Genetic control of bone formation. Annu. Rev. Cell Dev. Biol. 25, 629-648
4. Maes, C., Kobayashi, T., Selig, M. K., Torrekens, S., Roth, S. I., Mackem, S., Carmeliet, G., and Kronenberg, H. M. (2010) Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels. Dev. Cell 19, 329-344
5. Olson, E. N., and Nordheim, A. (2010) Linking actin dynamics and gene transcription to drive cellular motile functions. Nat. Rev. Mol. Cell Biol. 11, 353-365
6. Witke, W. (2004) The role of profilin complexes in cell motility and other cellular processes. Trends Cell Biol. 14, 461-469
7. Witke, W., Sutherland, J. D., Sharpe, A., Arai, M., and Kwiatkowski, D. J. (2001) Profilin I is essential for cell survival and cell division in early mouse development. Proc. Natl. Acad. Sci. U.S.A. 98, 3832-3836 (Pubitemid 32249857)
8. Böttcher, R. T., Wiesner, S., Braun, A., Wimmer, R., Berna, A., Elad, N., Medalia, O., Pfeifer, A., Aszódi, A., Costell, M., and Fässler, R. (2009) Profilin 1 is required for abscission during late cytokinesis of chondrocytes. EMBO J. 28, 1157-1169
9. Logan, M., Martin, J. F., Nagy, A., Lobe, C., Olson, E. N., and Tabin, C. J. (2002) Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis 33, 77-80 (Pubitemid 34651279)
10. Kawaguchi, J., Wilson, V., and Mee, P. J. (2002) Visualization of wholemount skeletal expression patterns of LacZ reporters using a tissue clearing protocol. Biotechniques 32, 66, 68-70, 72-73
11. McLeod, M. J. (1980) Differential staining of cartilage and bone in whole mouse fetuses by Alcian blue and alizarin red S. Teratology 22, 299-301
12. Hill, T. P., Später, D., Taketo, M. M., Birchmeier, W., and Hartmann, C. (2005) Canonical Wnt/β-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev. Cell 8, 727-738 (Pubitemid 40585295)
13. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival. Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63
14. Liang, C. C., Park, A. Y., and Guan, J. L. (2007) In vitro scratch assay. A convenient and inexpensive method for analysis of cell migration in vitro. Nat. Protoc. 2, 329-333 (Pubitemid 47040047)
15. Soriano, P. (1999) Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70-71
16. Durland, J. L., Sferlazzo, M., Logan, M., and Burke, A. C. (2008) Visualizing the lateral somitic frontier in the Prx1Cre transgenic mouse. J. Anat. 212, 590-602 (Pubitemid 351593964)
17. Xiong, J., Onal, M., Jilka, R. L., Weinstein, R. S., Manolagas, S. C., and O'Brien, C. A. (2011) Matrix-embedded cells control osteoclast formation. Nat. Med. 17, 1235-1241
18. CHEN, J. M. (1952) Studies on the morphogenesis of the mouse sternum. I. Normal embryonic development. J. Anat. 86, 373-386
19. CHEN, J. M. (1952) Studies on the morphogenesis of the mouse sternum. II. Experiments on the origin of the sternum and its capacity for self-differentiation in vitro. J. Anat. 86, 387-401
20. Liu, K. J., Arron, J. R., Stankunas, K., Crabtree, G. R., and Longaker, M. T. (2007) Chemical rescue of cleft palate and midline defects in conditional GSK-3β mice. Nature 446, 79-82 (Pubitemid 46348041)
21. Torre, M., Rapuzzi, G., Carlucci, M., Pio, L., and Jasonni, V. (2012) Phenotypic spectrum and management of sternal cleft: literature review and presentation of a new series. Eur. J. Cardiothorac. Surg. 41, 4-9
22. Kimura, A., Inose, H., Yano, F., Fujita, K., Ikeda, T., Sato, S., Iwasaki, M., Jinno, T., Ae, K., Fukumoto, S., Takeuchi, Y., Itoh, H., Imamura, T., Kawaguchi, H., Chung, U. I., Martin, J. F., Iseki, S., Shinomiya, K., and Takeda, S. (2010) Runx1 and Runx2 cooperate during sternal morphogenesis. Development 137, 1159-1167
23. Hart, A. W., Morgan, J. E., Schneider, J., West, K., McKie, L., Bhattacharya, S., Jackson, I. J., and Cross, S. H. (2006) Cardiac malformations and midline skeletal defects in mice lacking filamin A. Hum. Mol. Genet. 15, 2457-2467 (Pubitemid 44288699)
24. Colnot, C., Lu, C., Hu, D., and Helms, J. A. (2004) Distinguishing the contributions of the perichondrium, cartilage, and vascular endothelium to skeletal development. Dev. Biol. 269, 55-69
25. Galotto, M., Campanile, G., Robino, G., Cancedda, F. D., Bianco, P., and Cancedda, R. (1994) Hypertrophic chondrocytes undergo further differentiation to osteoblast-like cells and participate in the initial bone formation in developing chick embryo. J. Bone Miner. Res. 9, 1239-1249
26. Mödder, U. I., and Khosla, S. (2008) Skeletal stem/osteoprogenitor cells. Current concepts, alternate hypotheses, and relationship to the bone remodeling compartment. J. Cell Biochem. 103, 393-400 (Pubitemid 351171911)
27. Roach, H. I., and Erenpreisa, J. (1996) The phenotypic switch from chondrocytes to bone-forming cells involves asymmetric cell division and apoptosis. Connect. Tissue Res. 35, 85-91 (Pubitemid 27118840)
28. Maes, C., Carmeliet, P., Moermans, K., Stockmans, I., Smets, N., Collen, D., Bouillon, R., and Carmeliet, G. (2002) Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Mech. Dev. 111, 61-73 (Pubitemid 34136979)
29. Dy, P., Wang, W., Bhattaram, P., Wang, Q., Wang, L., Ballock, R. T., and Lefebvre, V. (2012) Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes. Dev. Cell 22, 597-609
30. Komori, T., Yagi, H., Nomura, S., Yamaguchi, A., Sasaki, K., Deguchi, K., Shimizu, Y., Bronson, R. T., Gao, Y. H., Inada, M., Sato, M., Okamoto, R., Kitamura, Y., Yoshiki, S., and Kishimoto, T. (1997) Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89, 755-764 (Pubitemid 27516178)
31. Otto, F., Thornell, A. P., Crompton, T., Denzel, A., Gilmour, K. C., Rosewell, I. R., Stamp, G. W., Beddington, R. S., Mundlos, S., Olsen, B. R., Selby, P. B., and Owen, M. J. (1997) Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89, 765-771 (Pubitemid 27516179)
32. Colnot, C., de la Fuente, L., Huang, S., Hu, D., Lu, C., St-Jacques, B., and Helms, J. A. (2005) Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development 132, 1057-1067 (Pubitemid 40484939)
33. St-Jacques, B., Hammerschmidt, M., and McMahon, A. P. (1999) Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 13, 2072-2086 (Pubitemid 29407348)
34. Nakashima, K., Zhou, X., Kunkel, G., Zhang, Z., Deng, J. M., Behringer, R. R., and de Crombrugghe, B. (2002) The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108, 17-29 (Pubitemid 34137009)
35. Yang, F., Schwartz, Z., Swain, L. D., Lee, C. C., Bowman, B. H., Boyan, B. D. (1991) Alpha 2-HS-glycoprotein. Expression in chondrocytes and augmentation of alkaline phosphatase and phospholipase A2 activity. Bone 12, 7-15
36. Aizawa, T., Kon, T., Einhorn, T. A., Gerstenfeld, L. C. (2001) Induction of apoptosis in chondrocytes by tumor necrosis factor α. J. Orthop. Res. 19, 785-796 (Pubitemid 32799063)