Immunohistochemical expression of DCUN1D1 in non-small cell lung carcinoma: Its relation to brain metastasis

Cancer Research and Treatment

Volumn 44, Issue 1, 2012, Pages 57-62

  Yoo, Jinyoung ^a   Lee, Seong Hak ^b   Lym, Kwang Il ^b   Park, Sonya Youngju ^b   Yang, Seung Ho ^a   Yoo, Chang Young ^a   Jung, Ji Han ^a   Kang, Seok Jin ^a   Kang, Chang Suk ^c  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

^c The Catholic University of Korea   (South Korea)

Author keywords

DCUN1D1 protein; Neoplasm metastasis; Non small cell lung carcinoma

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN METASTASIS; CANCER CLASSIFICATION; CANCER RISK; CANCER STAGING; CORRELATION ANALYSIS; DCUN1D1 GENE; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; ONCOGENE; PRIMARY TUMOR; STATISTICAL SIGNIFICANCE;

EID: 84866930450     PISSN: 15982998     EISSN: 20059256     Source Type: Journal    
DOI: 10.4143/crt.2012.44.1.57     Document Type: Article

References (15)

1. Schuette W. Treatment of brain metastases from lung cancer: chemotherapy. Lung Cancer. 2004;45 Suppl 2:S253-7.
2. Palmieri D, Chambers AF, Felding-Habermann B, Huang S, Steeg PS. The biology of metastasis to a sanctuary site. Clin Cancer Res. 2007;13:1656-62.
3. Saad AG, Yeap BY, Thunnissen FB, Pinkus GS, Pinkus JL, Loda M, et al. Immunohistochemical markers associated with brain metastases in patients with nonsmall cell lung carcinoma. Cancer. 2008;113:2129-38.
4. Arnold SM, Young AB, Munn RK, Patchell RA, Nanayakkara N, Markesbery WR. Expression of p53, bcl-2, E-cadherin, matrix metalloproteinase-9, and tissue inhibitor of metalloproteinases-1 in paired primary tumors and brain metastasis. Clin Cancer Res. 1999;5:4028-33.
5. Shabani HK, Kitange G, Tsunoda K, Anda T, Tokunaga Y, Shibata S, et al. Immunohistochemical expression of E-cadherin in metastatic brain tumors. Brain Tumor Pathol. 2003;20:7-12.
6. Grinberg-Rashi H, Ofek E, Perelman M, Skarda J, Yaron P, Hajdúch M, et al. The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain. Clin Cancer Res. 2009;15:1755-61.
7. Singh B, Gogineni SK, Sacks PG, Shaha AR, Shah JP, Stoffel A, et al. Molecular cytogenetic characterization of head and neck squamous cell carcinoma and refinement of 3q amplification. Cancer Res. 2001;61:4506-13.
8. Sarkaria I, O-charoenrat P, Talbot SG, Reddy PG, Ngai I, Maghami E, et al. Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas. Cancer Res. 2006;66:9437-44.
9. Broderick SR, Golas BJ, Pham D, Towe CW, Talbot SG, Kaufman A, et al. SCCRO promotes glioma formation and malignant progression in mice. Neoplasia. 2010;12:476-84.
10. Sarkaria IS, Pham D, Ghossein RA, Talbot SG, Hezel M, Dudas ME, et al. SCCRO expression correlates with invasive progression in bronchioloalveolar carcinoma. Ann Thorac Surg. 2004;78:1734-41.
11. O-charoenrat P, Sarkaria I, Talbot SG, Reddy P, Dao S, Ngai I, et al. SCCRO (DCUN1D1) induces extracellular matrix invasion by activating matrix metalloproteinase 2. Clin Cancer Res. 2008;14:6780-9.
12. Kim AY, Bommeljé CC, Lee BE, Yonekawa Y, Choi L, Morris LG, et al. SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation. J Biol Chem. 2008;283:33211-20.
13. Talbot SG, O-charoenrat P, Sarkaria IS, Ghossein R, Reddy P, Ngai I, et al. Squamous cell carcinoma related oncogene regulates angiogenesis through vascular endothelial growth factor-A. Ann Surg Oncol. 2004;11:530-4.
14. Yoo J, Jung JH, Lee MA, Seo KJ, Shim BY, Kim SH, et al. Immunohistochemical analysis of non-small cell lung cancer: correlation with clinical parameters and prognosis. J Korean Med Sci. 2007;22:318-25.
15. Singh B, Stoffel A, Gogineni S, Poluri A, Pfister DG, Shaha AR, et al. Amplification of the 3q26.3 locus is associated with progression to invasive cancer and is a negative prognostic factor in head and neck squamous cell carcinomas. Am J Pathol. 2002;161:365-71.