SFC Instrument modification to allow greater flexibility in method development by generating mixtures of solvents and modifiers on-line for mobile phase B optimization

Chromatographia

Volumn 75, Issue 19-20, 2012, Pages 1185-1190

  Alexander, Anthony J ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Pharmaceutical impurity profiling; SFC; SFC instrument modification; Supercritical fluid chromatography

Indexed keywords

ARIPIPRAZOLE; METHANOL;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL REACTION KINETICS; DRUG IMPURITY; FLOW KINETICS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SEPARATION TECHNIQUE; SOLVENT EFFECT; SUPERCRITICAL FLUID CHROMATOGRAPHY;

EID: 84866914954     PISSN: 00095893     EISSN: 16121112     Source Type: Journal    
DOI: 10.1007/s10337-012-2291-8     Document Type: Article

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