ANG-(1-7) reduces ANG II-induced insulin resistance by enhancing Akt phosphorylation via a Mas receptor-dependent mechanism in rat skeletal muscle

Biochemical and Biophysical Research Communications

Volumn 426, Issue 3, 2012, Pages 369-373

  Prasannarong, Mujalin ^a,b   Santos, Fernando R ^a   Henriksen, Erik J ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b Mahidol University ^*  (Thailand)

Author keywords

A779 peptide; Glucose transport; Insulin signaling; Soleus muscle

Indexed keywords

ANGIOTENSIN II; ANGIOTENSIN[1-7]; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; INSULIN; MAS RECEPTOR; PROTEIN; PROTEIN KINASE B; SERINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ENZYME PHOSPHORYLATION; GLUCOSE TRANSPORT; IN VITRO STUDY; INSULIN RESISTANCE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SOLEUS MUSCLE;

ANGIOTENSIN II; ANIMALS; BIOLOGICAL TRANSPORT; FEMALE; GLUCOSE; INSULIN RESISTANCE; MUSCLE, SKELETAL; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, ZUCKER; RECEPTORS, G-PROTEIN-COUPLED;

MAMMALIA; RATTUS;

EID: 84866893212     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.08.093     Document Type: Article

References (23)

1. Reaven G.M. Role of insulin resistance in human disease (syndrome X): an expanded definition. Annu. Rev. Med. 1993, 44:121-131.
2. Zimmet P., Magliano D., Matsuzawa Y., Alberti G., Shaw J. The metabolic syndrome: a global public health problem and a new definition. J. Atheroscler. Thromb. 2005, 12:295-300.
3. Huang P.L. A comprehensive definition for metabolic syndrome. Dis. Models Mech. 2009, 2:231-237.
4. Eckel R.H., Grundy S.M., Zimmet P.Z. The metabolic syndrome. Lancet 2005, 365:1415-1428.
5. Grundy S.M., Hansen B., Smith S.C., Cleeman J.I., Kahn R.A. Clinical management of metabolic syndrome: report of the American Heart Association/National Heart Lung and Blood Institute/American Diabetes Association conference on scientific issues related to management. Circulation 2004, 109:551-556.
6. Kahn R., Buse J., Ferrannini E., Stern M. The metabolic syndrome: time for a critical appraisal Joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 2005, 48:1684-1699.
7. Santos R.A., Ferreira A.J., Simões E. Silva A.C. Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis. Exp. Physiol. 2008, 93:519-527.
8. Xu P., Sriramula S., Lazartigues E. ACE2/ANG-(1-7)/Mas pathway in the brain the axis of good Am. J. Physiol. Regul. Integr. Comp. Physiol. 2011, 300:R804-R817.
9. Cat A.N., Touyz R.M. A new look at the renin-angiotensin system - focusing on the vascular system. Peptides 2011, 32:2141-2150.
10. Ogihara T., Asano T., Ando K., Chiba Y., Sakoda H., Anai M., Shojima N., Ono H., Onishi Y., Fujishiro M., Katagiri H., Fukushima Y., Kikuchi M., Noguchi N., Aburatani H., Komuro I., Fujita T. Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling. Hypertension 2002, 40:872-879.
11. Muñoz M.C., Giani J.F., Dominici F.P. Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas. Regul. Pept. 2010, 161:1-7.
12. Diamond-Stanic M.K., Henriksen E.J. Direct inhibition by angiotensin II of insulin dependent glucose transport activity in mammalian skeletal muscle involves a ROS-dependent mechanism. Arch. Physiol. Biochem. 2010, 116:88-95.
13. Giani J.F., Mayer M.A., Muñoz M.C., Silberman E.A., Höcht C., Taira C.A., Gironacci M.M., Turyn D., Dominici F.P. Chronic infusion of angiotensin-(1-7) improves insulin resistance and hypertension induced by a high-fructose diet in rats Am. J. Physiol. Endocrinol. Metab. 2009, 296:E262-E271.
14. Henriksen E.J., Diamond-Stanic M.K., Marchionne E.M. Oxidative stress and the etiology of insulin resistance and type 2 diabetes. Free Radic. Biol. Med. 2011, 51:993-999.
15. Santos R.A., Campagnole-Santos M.J., Baracho N.C., Fontes M.A., Silva L.C., Neves L.A., Oliveira D.R., Caligiorne S.M., Rodrigues A.R., Gropen Júnior C., et al. Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors. Brain Res. Bull. 1994, 35:293-298.
16. Henriksen E.J., Bourey R.E., Rodnick K.J., Koranyi L., Permutt M.A., Holloszy J.O. Glucose transporter protein content and glucose transport capacity in rat skeletal muscles. Am. J. Physiol. Endocrinol. Metab. 1990, 259:E593-E598.
17. Henriksen E.J., Halseth A.E. Early alterations in soleus GLUT-4 glucose transport and glycogen in voluntary running rats. J. Appl. Physiol. 1994, 76:1862-1867.
18. Henriksen E.J., Jacob S. Effects of captopril on glucose transport activity in skeletal muscle of obese Zucker rats. Metabolism 1995, 44:267-272.
19. Ferreira A.J., Santos R.A.S., Bradford C.N., Mecca A.P., Sumners C., Katovich M.J., Raizada M.K. Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases. Hypertension 2010, 55:207-213.
20. Henriksen E.J. Improvement of insulin sensitivity by antagonism of the renin-angiotensin system. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2007, 293:R974-R980.
21. Wei Y., Sowers J.R., Nistala R., Gong H., Uptergrove G.M., Clark S.E., Morris E.M., Szary N., Manrique C., Stump C.S. Angiotensin II-induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells. J. Biol. Chem. 2006, 281:35137-35146.
22. Csibi A., Communi D., Müller N., Bottari S.P. Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms. PLoS One 2010, 5:e10070.
23. Griendling K.K., Minieri C.A., Ollerenshaw J.D., Alexander R.W. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ. Res. 1994, 74:1141-1148.