-
1
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006;444:840-846.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
2
-
-
79955977850
-
The impact of obesity on diabetes mellitus and the role of bariatric surgery
-
Gill RS, Sharma AM, Gill SS, et al. The impact of obesity on diabetes mellitus and the role of bariatric surgery. Maturitas, 69:137-140.
-
Maturitas
, vol.69
, pp. 137-140
-
-
Gill, R.S.1
Sharma, A.M.2
Gill, S.S.3
-
3
-
-
79960016921
-
Type 2 diabetes and obesity: Genomics and the clinic
-
Travers ME, McCarthy MI. Type 2 diabetes and obesity: genomics and the clinic. Hum Genet 2011;130:41-58.
-
(2011)
Hum Genet
, vol.130
, pp. 41-58
-
-
Travers, M.E.1
McCarthy, M.I.2
-
4
-
-
84857034781
-
Blockade of kinin B(1) receptor reverses plasma fatty acids composition changes and body and tissue fat gain in a rat model of insulin resistance
-
Dias JP, Couture R. Blockade of kinin B(1) receptor reverses plasma fatty acids composition changes and body and tissue fat gain in a rat model of insulin resistance. Diabetes Obes Metab 2012;14:244-253.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 244-253
-
-
Dias, J.P.1
Couture, R.2
-
5
-
-
0035671709
-
Role of the B(2) receptor of bradykinin in insulin sensitivity
-
Duka I, Shenouda S, Johns C, et al. Role of the B(2) receptor of bradykinin in insulin sensitivity. Hypertension 2001;38:1355-1360.
-
(2001)
Hypertension
, vol.38
, pp. 1355-1360
-
-
Duka, I.1
Shenouda, S.2
Johns, C.3
-
6
-
-
37549045287
-
Swimming training exacerbates pathological cardiac hypertrophy in kinin B2 receptordeficient mice
-
Batista EC, Batista EC, Ramalho JD, et al. Swimming training exacerbates pathological cardiac hypertrophy in kinin B2 receptordeficient mice. Int Immunopharmacol 2008;8:271-275.
-
(2008)
Int Immunopharmacol
, vol.8
, pp. 271-275
-
-
Batista, E.C.1
Batista, E.C.2
Ramalho, J.D.3
-
7
-
-
48249123873
-
Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity
-
Mori MA, Araujo RC, Reis FC, et al. Kinin B1 receptor deficiency leads to leptin hypersensitivity and resistance to obesity. Diabetes 2008; 57:1491-1500.
-
(2008)
Diabetes
, vol.57
, pp. 1491-1500
-
-
Mori, M.A.1
Araujo, R.C.2
Reis, F.C.3
-
8
-
-
0032040381
-
Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway
-
Kishi K, Muromoto N, Nakaya Y, et al. Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway. Diabetes 1998;47:550-558.
-
(1998)
Diabetes
, vol.47
, pp. 550-558
-
-
Kishi, K.1
Muromoto, N.2
Nakaya, Y.3
-
9
-
-
33645760265
-
Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function
-
Araujo RC, Mori MA, Merino VF, et al. Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function. Biol Chem 2006;387:431-436.
-
(2006)
Biol Chem
, vol.387
, pp. 431-436
-
-
Araujo, R.C.1
Mori, M.A.2
Merino, V.F.3
-
10
-
-
9044244913
-
Bradykinin enhances GLUT4 translocation through the increase of insulin receptor tyrosine kinase in primary adipocytes: Evidence that bradykinin stimulates the insulin signalling pathway
-
Isami S, Kishikawa H, Araki E, et al. Bradykinin enhances GLUT4 translocation through the increase of insulin receptor tyrosine kinase in primary adipocytes: evidence that bradykinin stimulates the insulin signalling pathway. Diabetologia 1996;39:412-420.
-
(1996)
Diabetologia
, vol.39
, pp. 412-420
-
-
Isami, S.1
Kishikawa, H.2
Araki, E.3
-
11
-
-
0031958116
-
Bradykinin potentiates insulinstimulated glucose uptake and enhances insulin signal through the bradykinin B2 receptor in dog skeletal muscle and rat L6 myoblasts
-
Miyata T, Taguchi T, Uehara M, et al. Bradykinin potentiates insulinstimulated glucose uptake and enhances insulin signal through the bradykinin B2 receptor in dog skeletal muscle and rat L6 myoblasts. Eur J Endocrinol 1998;138:344-352.
-
(1998)
Eur J Endocrinol
, vol.138
, pp. 344-352
-
-
Miyata, T.1
Taguchi, T.2
Uehara, M.3
-
12
-
-
33750861042
-
Bradykinin augments insulin-stimulated glucose transport in rat adipocytes via endothelial nitric oxide synthase-mediated inhibition of Jun NH2-terminal kinase
-
Beard KM, Lu H, Ho K, et al. Bradykinin augments insulin-stimulated glucose transport in rat adipocytes via endothelial nitric oxide synthase-mediated inhibition of Jun NH2-terminal kinase. Diabetes 2006;55:2678-2687.
-
(2006)
Diabetes
, vol.55
, pp. 2678-2687
-
-
Beard, K.M.1
Lu, H.2
Ho, K.3
-
13
-
-
0035105826
-
Involvement of bradykinin and nitric oxide in leptin-mediated glucose uptake in skeletal muscle
-
Shiuchi T, Nakagami H, Iwai M, et al. Involvement of bradykinin and nitric oxide in leptin-mediated glucose uptake in skeletal muscle. Endocrinology 2001;142:608-612.
-
(2001)
Endocrinology
, vol.142
, pp. 608-612
-
-
Shiuchi, T.1
Nakagami, H.2
Iwai, M.3
-
14
-
-
35348910740
-
Involvement of protein kinase A in nitric oxide stimulating effect on a BK(Ca) channel of human dermal fibroblasts
-
Roh S, Choi S, Lim I. Involvement of protein kinase A in nitric oxide stimulating effect on a BK(Ca) channel of human dermal fibroblasts. J Invest Dermatol 2007;127:2533-2538.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 2533-2538
-
-
Roh, S.1
Choi, S.2
Lim, I.3
-
15
-
-
0036711810
-
ACE inhibitor improves insulin resistance in diabetic mouse via bradykinin and NO
-
Shiuchi T, Cui TX, Wu L, et al. ACE inhibitor improves insulin resistance in diabetic mouse via bradykinin and NO. Hypertension 2002;40: 329-334.
-
(2002)
Hypertension
, vol.40
, pp. 329-334
-
-
Shiuchi, T.1
Cui, T.X.2
Wu, L.3
-
16
-
-
77049099787
-
Altered cardiac bradykinin metabolism in experimental diabetes caused by the variations of angiotensin-converting enzyme and other peptidases
-
Adam A, Leclair P, Montpas N, et al. Altered cardiac bradykinin metabolism in experimental diabetes caused by the variations of angiotensin-converting enzyme and other peptidases. Neuropeptides, 44:69-75.
-
Neuropeptides
, vol.44
, pp. 69-75
-
-
Adam, A.1
Leclair, P.2
Montpas, N.3
-
17
-
-
0031032720
-
Interactions of the kallikreinkinin and renin-angiotensin systems in experimental diabetes
-
Vora JP, Oyama TT, Thompson MM, et al. Interactions of the kallikreinkinin and renin-angiotensin systems in experimental diabetes. Diabetes 1997;46:107-112.
-
(1997)
Diabetes
, vol.46
, pp. 107-112
-
-
Vora, J.P.1
Oyama, T.T.2
Thompson, M.M.3
-
18
-
-
0036195793
-
Multiple interactions between the renin-angiotensin and the kallikrein-kinin systems: Role of ACE inhibition and AT1 receptor blockade
-
Tschope C, Schultheiss HP, Walther T. Multiple interactions between the renin-angiotensin and the kallikrein-kinin systems: role of ACE inhibition and AT1 receptor blockade. J Cardiovasc Pharmacol 2002;39:478-487.
-
(2002)
J Cardiovasc Pharmacol
, vol.39
, pp. 478-487
-
-
Tschope, C.1
Schultheiss, H.P.2
Walther, T.3
-
19
-
-
0030728725
-
Effect of captopril, losartan, and bradykinin on early steps of insulin action
-
Carvalho CR, Thirone AC, Gontijo JA, et al. Effect of captopril, losartan, and bradykinin on early steps of insulin action. Diabetes 1997;46: 1950-1957.
-
(1997)
Diabetes
, vol.46
, pp. 1950-1957
-
-
Carvalho, C.R.1
Thirone, A.C.2
Gontijo, J.A.3
-
20
-
-
79952219329
-
Participation of the liver gluconeogenesis in the glibenclamide-induced hypoglycaemia in rats
-
Geisler SA, Felisberto-Junior AM, Tavoni TM, et al. Participation of the liver gluconeogenesis in the glibenclamide-induced hypoglycaemia in rats. Cell Biochem Funct, 29:81-86.
-
Cell Biochem Funct
, vol.29
, pp. 81-86
-
-
Geisler, S.A.1
Felisberto-Junior, A.M.2
Tavoni, T.M.3
-
21
-
-
79251557845
-
Targeting Forkhead box O1 from the concept to metabolic diseases: Lessons from mouse models
-
Cheng Z, White MF. Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models. Antioxid Redox Signal, 14:649-661.
-
Antioxid Redox Signal
, vol.14
, pp. 649-661
-
-
Cheng, Z.1
White, M.F.2
-
22
-
-
68949163797
-
Efficient method for obtaining Lep(ob)/Lep(ob)-derived animal models using adipose tissue transplantations
-
Barros CC, Almeida SS, Mori MA, et al. Efficient method for obtaining Lep(ob)/Lep(ob)-derived animal models using adipose tissue transplantations. Int J Obes 2009;33:938-944.
-
(2009)
Int J Obes
, vol.33
, pp. 938-944
-
-
Barros, C.C.1
Almeida, S.S.2
Mori, M.A.3
-
23
-
-
3242883440
-
Targeted expression of a dominantnegative N-cadherin in vivo delays peak bone mass and increases adipogenesis
-
Castro CH, Shin CS, Stains JP, et al. Targeted expression of a dominantnegative N-cadherin in vivo delays peak bone mass and increases adipogenesis. J Cell Sci 2004;117(Pt 13):2853-2864.
-
(2004)
J Cell Sci
, vol.117
, Issue.PART 13
, pp. 2853-2864
-
-
Castro, C.H.1
Shin, C.S.2
Stains, J.P.3
-
24
-
-
0031795938
-
Influence of age, hyperglycemia, leptin, and NPY on islet blood flow in obese-hyperglycemic mice
-
Carlsson PO, Andersson A, Jansson L. Influence of age, hyperglycemia, leptin, and NPY on islet blood flow in obese-hyperglycemic mice. Am J Physiol 1998;275(4 Pt 1):E594-E601.
-
(1998)
Am J Physiol
, vol.275
, Issue.4 PART 1
-
-
Carlsson, P.O.1
Andersson, A.2
Jansson, L.3
-
25
-
-
0014291187
-
Development of the obese-hyperglycaemic syndrome in mice
-
Westman S. Development of the obese-hyperglycaemic syndrome in mice. Diabetologia 1968;4:141-149.
-
(1968)
Diabetologia
, vol.4
, pp. 141-149
-
-
Westman, S.1
-
26
-
-
34249799917
-
The physiology of obese-hyperglycemic mice [ob/ob mice]
-
Lindstrom P. The physiology of obese-hyperglycemic mice [ob/ob mice]. ScientificWorldJournal 2007;7:666-685.
-
(2007)
ScientificWorldJournal
, vol.7
, pp. 666-685
-
-
Lindstrom, P.1
-
27
-
-
55849106967
-
Visceral adiposity and its anatomical distribution as predictors of the metabolic syndrome and cardiometabolic risk factor levels
-
Demerath EW, Reed D, Rogers N, et al. Visceral adiposity and its anatomical distribution as predictors of the metabolic syndrome and cardiometabolic risk factor levels. Am J Clin Nutr 2008;88:1263-1271.
-
(2008)
Am J Clin Nutr
, vol.88
, pp. 1263-1271
-
-
Demerath, E.W.1
Reed, D.2
Rogers, N.3
-
28
-
-
61449209861
-
Adipose tissue distribution is different in type 2 diabetes
-
Gallagher D, Kelley DE, Yim JE, et al. Adipose tissue distribution is different in type 2 diabetes. Am J Clin Nutr 2009;89:807-814.
-
(2009)
Am J Clin Nutr
, vol.89
, pp. 807-814
-
-
Gallagher, D.1
Kelley, D.E.2
Yim, J.E.3
-
29
-
-
0141566770
-
Hepatic glucose metabolism in humans-its role in health and disease
-
Roden M, Bernroider E. Hepatic glucose metabolism in humans-its role in health and disease. Best Pract Res Clin Endocrinol Metab 2003;17:365-383.
-
(2003)
Best Pract Res Clin Endocrinol Metab
, vol.17
, pp. 365-383
-
-
Roden, M.1
Bernroider, E.2
-
30
-
-
79956320989
-
Discovery of a novel site regulating glucokinase activity following characterization of a new mutation causing hyperinsulinemic hypoglycemia in humans
-
Beer NL, van de Bunt M, Colclough K, et al. Discovery of a novel site regulating glucokinase activity following characterization of a new mutation causing hyperinsulinemic hypoglycemia in humans. J Biol Chem, 286:19118-19126.
-
J Biol Chem
, vol.286
, pp. 19118-19126
-
-
Beer, N.L.1
Van De Bunt, M.2
Colclough, K.3
-
31
-
-
67749142348
-
Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes
-
Samuel VT, Beddow SA, Iwasaki T, et al. Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes. Proc Natl Acad Sci USA 2009;106:12121-12126.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12121-12126
-
-
Samuel, V.T.1
Beddow, S.A.2
Iwasaki, T.3
-
32
-
-
26644472453
-
Glucocorticoids regulate transcription of the gene for phosphoenolpyruvate carboxykinase in the liver via an extended glucocorticoid regulatory unit
-
Cassuto H, Kochan K, Chakravarty K, et al. Glucocorticoids regulate transcription of the gene for phosphoenolpyruvate carboxykinase in the liver via an extended glucocorticoid regulatory unit. J Biol Chem 2005;280:33873-33884.
-
(2005)
J Biol Chem
, vol.280
, pp. 33873-33884
-
-
Cassuto, H.1
Kochan, K.2
Chakravarty, K.3
-
33
-
-
82255185902
-
Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: Induction of renal and intestinal gluconeogenesis by glucagon
-
Mutel E, Gautier-Stein A, Abdul-Wahed A, et al. Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon. Diabetes, 60:3121-3131.
-
Diabetes
, vol.60
, pp. 3121-3131
-
-
Mutel, E.1
Gautier-Stein, A.2
Abdul-Wahed, A.3
-
34
-
-
79251544870
-
Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1
-
Wei D, Tao R, Zhang Y, et al. Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1. Am J Physiol Endocrinol Metab, 300:E312-E320.
-
Am J Physiol Endocrinol Metab
, vol.300
-
-
Wei, D.1
Tao, R.2
Zhang, Y.3
-
35
-
-
78049292405
-
Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis
-
Yoon YS, Lee MW, Ryu D, et al. Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis. Proc Natl Acad Sci USA, 107:17704-17709.
-
Proc Natl Acad Sci USA
, vol.107
, pp. 17704-17709
-
-
Yoon, Y.S.1
Lee, M.W.2
Ryu, D.3
-
36
-
-
77952599131
-
PGC-1alpha coactivates estrogen-related receptor-alpha to induce the expression of glucokinase
-
Zhu LL, Liu Y, Cui AF, et al. PGC-1alpha coactivates estrogen-related receptor-alpha to induce the expression of glucokinase. Am J Physiol Endocrinol Metab, 298:E1210-E1218.
-
Am J Physiol Endocrinol Metab
, vol.298
-
-
Zhu, L.L.1
Liu, Y.2
Cui, A.F.3
-
37
-
-
69949101448
-
Forkhead box transcription factor O1 inhibits cholesterol 7alpha-hydroxylase in human hepatocytes and in high fat diet-fed mice
-
Li T, Ma H, Park YJ, et al. Forkhead box transcription factor O1 inhibits cholesterol 7alpha-hydroxylase in human hepatocytes and in high fat diet-fed mice. Biochem Biophys Acta 2009;1791:991-996.
-
(2009)
Biochem Biophys Acta
, vol.1791
, pp. 991-996
-
-
Li, T.1
Ma, H.2
Park, Y.J.3
-
38
-
-
41849104205
-
Structure/function relationships underlying regulation of FOXO transcription factors
-
Obsil T, Obsilova V. Structure/function relationships underlying regulation of FOXO transcription factors. Oncogene 2008;27: 2263-2275.
-
(2008)
Oncogene
, vol.27
, pp. 2263-2275
-
-
Obsil, T.1
Obsilova, V.2
-
39
-
-
25444442080
-
Triple layer control: Phosphorylation, acetylation and ubiquitination of FOXO proteins
-
Vogt PK, Jiang H, Aoki M. Triple layer control: phosphorylation, acetylation and ubiquitination of FOXO proteins. Cell Cycle 2005;4: 908-913.
-
(2005)
Cell Cycle
, vol.4
, pp. 908-913
-
-
Vogt, P.K.1
Jiang, H.2
Aoki, M.3
-
40
-
-
39849107173
-
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver
-
Cintra DE, Pauli JR, Araujo EP, et al. Interleukin-10 is a protective factor against diet-induced insulin resistance in liver. J Hepatol 2008;48: 628-637.
-
(2008)
J Hepatol
, vol.48
, pp. 628-637
-
-
Cintra, D.E.1
Pauli, J.R.2
Araujo, E.P.3
-
41
-
-
45549090182
-
Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation
-
Dong XC, Copps KD, Guo S, et al. Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation. Cell Metab 2008;8:65-76.
-
(2008)
Cell Metab
, vol.8
, pp. 65-76
-
-
Dong, X.C.1
Copps, K.D.2
Guo, S.3
-
42
-
-
0141839103
-
Novel concepts in insulin regulation of hepatic gluconeogenesis
-
Barthel A, Schmoll D. Novel concepts in insulin regulation of hepatic gluconeogenesis. Am J Physiol Endocrinol Metab 2003;285:E685-E692.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.285
-
-
Barthel, A.1
Schmoll, D.2
-
43
-
-
33744905787
-
PGC-1alpha: A potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes
-
Soyal S, Krempler F, Oberkofler H, et al. PGC-1alpha: a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes. Diabetologia 2006;49:1477-1488.
-
(2006)
Diabetologia
, vol.49
, pp. 1477-1488
-
-
Soyal, S.1
Krempler, F.2
Oberkofler, H.3
-
45
-
-
77249138841
-
Early hepatic insulin resistance in mice: A metabolomics analysis
-
Li LO, Hu YF, Wang L, et al. Early hepatic insulin resistance in mice: a metabolomics analysis. Mol Endocrinol, 24:657-666.
-
Mol Endocrinol
, vol.24
, pp. 657-666
-
-
Li, L.O.1
Hu, Y.F.2
Wang, L.3
-
46
-
-
0029882234
-
Bradykinin increases intracellular free Ca2 + concentration and promotes insulin secretion in the clonal beta-cell line, HIT-T15
-
Saito Y, Kato M, Kubohara Y, et al. Bradykinin increases intracellular free Ca2 + concentration and promotes insulin secretion in the clonal beta-cell line, HIT-T15. Biochem Biophys Res Commun 1996;221: 577-580.
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 577-580
-
-
Saito, Y.1
Kato, M.2
Kubohara, Y.3
-
47
-
-
0034266033
-
Bradykinin enhances membrane electrical activity of pancreatic beta cells in the presence of low glucose concentrations
-
Moura AS. Bradykinin enhances membrane electrical activity of pancreatic beta cells in the presence of low glucose concentrations. Braz J Med Biol Res 2000;33:1089-1092.
-
(2000)
Braz J Med Biol Res
, vol.33
, pp. 1089-1092
-
-
Moura, A.S.1
-
48
-
-
0030846821
-
The effect of bradykinin on secretion of insulin, glucagon, and somatostatin from the perfused rat pancreas
-
Yang C, Chao J, Hsu WH. The effect of bradykinin on secretion of insulin, glucagon, and somatostatin from the perfused rat pancreas. Metabolism 1997;46:1113-1115.
-
(1997)
Metabolism
, vol.46
, pp. 1113-1115
-
-
Yang, C.1
Chao, J.2
Hsu, W.H.3
-
49
-
-
0030967944
-
Mechanisms of bradykinin-induced insulin secretion in clonal beta cell line RINm5F
-
Yang C, Lee B, Chen TH, et al. Mechanisms of bradykinin-induced insulin secretion in clonal beta cell line RINm5F. J Pharmacol Exp Ther 1997;282:1247-1252.
-
(1997)
J Pharmacol Exp Ther
, vol.282
, pp. 1247-1252
-
-
Yang, C.1
Lee, B.2
Chen, T.H.3
|