Nano-hydroxyapatite/fibrin glue/recombinant human osteogenic protein-1 artificial bone for repair of bone defect in an animal model

Micro and Nano Letters

Volumn 7, Issue 5, 2012, Pages 467-471

  Zhu, Weimin ^a   Lu, Wei ^a   Zhang, Xiaojun ^b   Cai, Zhimin ^a   Liu, Haifeng ^a   Peng, Liangquan ^a   Li, Hao ^a   Han, Yun ^a   Fen, Wenzhe ^a   Wang, Daping ^a   Zeng, Yanjun ^b  

^a THE FIRST AFFILIATED HOSPITAL OF SHENZHEN UNIVERSITY   (China)

^b BEIJING UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; ARTIFICIAL BONES; BIOACTIVE MATERIAL; BIOMECHANICAL ANALYSIS; BIOMECHANICAL PROPERTIES; BONE DEFECT; BONE FORMATION; BONE IMAGING; BONE INDUCTION; CONTROL GROUPS; DEFECT SITES; ELECTRONIC MICROSCOPES; HUMAN BONES; NANO-HA; NANO-HYDROXYAPATITE; NEW ZEALAND WHITE RABBIT; OSTEOGENIC;

BIOMECHANICS; BONE CEMENT; DEFECTS; NANOCOMPOSITES; PROTEINS; RADIOISOTOPES; REPAIR; TISSUE;

BONE;

FIBRIN GLUE; HYDROXYAPATITE; MEDRONATE TECHNETIUM TC 99M; RADIOISOTOPE; RECOMBINANT OSTEOGENIC PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL ORGAN; BIOCOMPATIBILITY; BONE CONDUCTION; BONE DEFECT; BONE REMODELING; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; EXPERIMENTAL RABBIT; MESENCHYME CELL; NONHUMAN; OSSIFICATION; RADIOGRAPHY; SCANNING ELECTRON MICROSCOPY; X RAY;

EID: 84866870137     PISSN: None     EISSN: 17500443     Source Type: Journal    
DOI: 10.1049/mnl.2012.0090     Document Type: Article

References (18)

1. Yoshikawa, M., and Toda, T.: ' Reconstruction of alveolar bone defect by calcium phosphate compounds ', J. Biomed. Mater. Res., 2000, 53, (4), p. 430-437 10.1002/1097-4636(2000)53:4<430::AID-JBM18>3.0.CO;2-E
2. Yuan J.M.: Chinese Patent ZL91106753.1, January 2000
3. Zhu, W., Zhang, X., and Wang, D.: et al. ' Experimental study on the conduction function f nano-hydroxyapatite artificial bone ', Micro Nano Lett., 2010, 1, (5), p. 19-27 10.1049/mnl.2009.0049
4. Zhu, W., Wang, D., and Zhang, X.: et al. ' An experimental study on the application of radionuclide imaging in repair of the bone defect ', Bosnian J. Basic Med. Sci., 2011, 11, (3), p. 143-148
5. Dai, L.S., Dang, Q.K., and Zheng, Z.G.: ' Experimental study of repairing the defects of articular cartilage with bone marrow stromal cells ', Zhongguo Linchuang Kangfu (Chin. J. Clin. Rehabil.), 2000, 4, p. 1508-1509
6. Tsai, C.H., Lin, R.M., and Ju, C.P.: et al. ' Bioresorption behavior of tetracalcium phosphate-derived calcium phosphate cement implanted in femur of rabbits ', Biomaterials, 2008, 29, (8), p. 984-993 10.1016/j.biomaterials.2007. 10.014 0142-9612
7. Goldberg, V.M., Stevenson, S., and Shaffer, J.W.: ' Biology of autografts and allografts ', Geds, F., Bone and cartilage allografts, (American Academy of Orthopaedic Surgeons, ParkRidge, IL, 1991), 1, p. 3-13
8. Jouve, J.L., Mottet, V., Cottalorda, J., Frayssinet, P., and Bollini, G.: ' Reimplantation of growth plate chondrocyte cultures in central growth plate defects: part 1. Characterization of cultures ', J. Pediatr. Orthop. B, 1998, 7, p. 167-173 10.1097/01202412-199804000-00016
9. Azami, M., Samadikuchaksaraei, A., and Poursamar, S.A.: et al. ' Synthesis and characterization of a laminated hydroxyapatite/gelatin nanocomposite scaffold with controlled pore structure for bone tissue engineering[J] ', Int. J. Artif. Organs, 2010, 33, (2), p. 86-95
10. Wang, D., Hu, Y.Y., and Zheng, C.Q.: et al. ' Healing of segmental bone defects byp-TCP/rhOP-1 composites with different degradation rate ', Chin. J. Orthop., 2001, 21, (7), p. 421-427
11. Zhu, W.M., Xiao, J.D., and Wang, D.P.: et al. ' Experimental study of nano-HA artificial bone with different pore sizes for repairing the radial defect ', Int. Orthop., 2008, 33, (2), p. 567-571 10.1007/s00264-008-0572-5
12. Wang, M., and Han, J.Q.: ' Histological evaluation of double osteogenic roles of rhBMP-7 combined with DBM ', Lett. Biotechnol., 2004, 15, (2), p. 146-147
13. Lu, J.X., Flautre, B., and Anselme, K.: et al. ' Role of interconnections in porous bioceramics on bone recolonization in vitro and in vivo ', J. Mater. Sci. Mater. Med., 1999, 10, p. 111 10.1023/A:1008973120918
14. Yamada, Y., Boo, J.S., and Ozawa, R.: et al. ' Bone regeneration following injection of mesenchymal stem cells and fibrin glue with a biodegradable scafold ', J. Craniomaxillofac. Surg., 2003, 31, (1), p. 27-33 10.1016/S1010-5182(02)00143-9
15. Zhu, W., Wang, D., and Zhang, X.: et al. ' Experimental study of nano-hydroxyapatite/recombinant human bone morphogenetic protein-2 composite artificial bone ', Artif. Cells Blood Substit. Biotechnol., 2010, 38, p. 150-156 10.3109/10731191003712756
16. Zhu, W., Wang, D., and Xiong, J.-Y.: et al. ' Revascularization study of the nano-hydroxyapatite artificial bone in repairing the bone defect ', J. Chinese Microcirculation, 2006, 10, (5), p. 344-348
17. Zhu, W., Wang, D., and Zhang, X.: et al. ' Experimental study of nano-hydroxyapatite/recombinant human bone morphogenetic protein-2 composite artifi cial bone ', Artif. Cells Blood Substit. Biotechnol., 2010, 38, p. 150-156 10.3109/10731191003712756
18. Wang, X., and Ye, J.: ' Variation of crystal structure of hydroxyapatite in calcium phosphate cement by the substitution of strontium ions ', J. Mater. Sci. Mater. Med., 2008, 19, (3), p. 1183-1186 10.1007/s10856-007-3209-0