Liquid-liquid slug flow separation in a slit shaped micro device

Chemical Engineering Journal

Volumn 207-208, Issue , 2012, Pages 440-444

  Gaakeer, W A ^a   de Croon, M H J M ^a   van der Schaaf, J ^a   Schouten, J C ^a  

^a EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

Capillary pressure; Micro separation device; Slug flow separation

Indexed keywords

CAPILLARY FORCE; HYDRAULIC PRESSURE; HYDROPHOBIC AND HYDROPHILIC; LIQUID-LIQUID SLUG FLOW; MICRO DEVICES; MICRO REACTOR; MICRO-SEPARATION; MICRO-SEPARATORS; SEPARATION EFFICIENCY; SLUG FLOW;

CAPILLARY TUBES; FLOW RATE; FLOW SEPARATION; HYDRAULIC FLUIDS; SEPARATION; SEPARATORS;

CAPILLARITY;

EID: 84866865953     PISSN: 13858947     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cej.2012.06.148     Document Type: Article

References (20)

1. Angelescu D.E., Mercier B., Siess D., Schroeder R. Microfluidic capillary separation and real-time spectroscopic analysis of specific components from multiphase mixtures. Anal. Chem. 2010, 82:2412-2420.
2. Arora A., Simone G., Salieb-Beugelaar G.B., Kim J.T., Manz A. Latest developments in micro total analysis systems. Anal. Chem. 2010, 82:4830-4847.
3. Barrow D.A., Castell O.K., Sykes N., Myers P., Ritchie H. A microfabricated graphitic carbon column for high performance liquid chromatography. J. Chromatogr. A. 2011, 1218:1983-1987.
4. Mawatari K., Kazoe Y., Aota A., Tsukahara T., Sato K., Kitamori T. Microflow systems for chemical synthesis and analysis: approaches to full integration of chemical process. J. Flow Chem. 2011, 1:3-12.
5. Ziogas A., Cominos V., Kolb G., Kost H.J., Werner B., Hessel V. Development of a microrectification apparatus for analytical and preparative applications. Chem. Eng. Technol. 2012, 35:58-71.
6. Calabrese G.S., Pissavini S. From batch to continuous flow processing in chemicals manufacturing. AIChE J. 2011, 57:828-834.
7. Hartman R.L., Jensen K.F. Microchemical systems for continuous-flow synthesis. Lab. Chip 2009, 9:2495-2507.
8. V. Hessel, P. Löb, U. Krtschil, H. Löwe, Microstructured reactors for development and production in pharmaceutical and fine chemistry, in: Ernst Schering Foundation Symp., vol. 3, Berlin, 2007, pp. 205-240.
9. Kockmann N., Gottsponer M., Roberge D.M. Scale-up concept of single-channel microreactors from process development to industrial production. Chem. Eng. J. 2011, 167:718-726.
10. Kuhn S., Noel T., Gu L., Heider P.L., Jensen K.F. A Teflon microreactor with integrated piezoelectric actuator to handle solid forming reactions. Lab. Chip 2011, 11:2488-2492.
11. Roberge D.M., Zimmermann B., Rainone F., Gottsponer M., Eyholzer M., Kockmann N. Microreactor technology and continuous processes in the fine chemical and pharmaceutical industry: Is the revolution underway?. Org. Process Res. Dev. 2008, 12:905-910.
12. Aota A., Hibara A., Kitamori T. Pressure balance at the liquid-liquid interface of micro countercurrent flows in microchips. Anal. Chem. 2007, 79:3919-3924.
13. Tesfai J.T., Perry R.N., Jablonski E.L. Water-in-oil emulsion separation within a milli-fluidic device. J. Colloid Interf. Sci. 2011, 354:895-899.
14. Kralj J.G., Sahoo H.R., Jensen K.F. Integrated continuous microfluidic liquid-liquid extraction. Lab. Chip 2007, 7:256-263.
15. Assmann N., von Rohr P.R. Extraction in microreactors: intensification by adding an inert gas phase. Chem. Eng. Proc. 2011, 50:822-827.
16. Scheiff F., Mendorf M., Agar D., Reis N., Mackley M. The separation of immiscible liquid slugs within plastic microchannels using a metallic hydrophilic sidestream. Lab. Chip 2011, 11:1022-1029.
17. Kashid M.N., Harshe Y.M., Agar D.W. Liquid-liquid slug flow in a capillary: an alternative to suspended drop or film contactors. Ind. Eng. Chem. Res. 2007, 46:8420-8430.
18. Visscher F., Gaakeer W.A., Granados Mendoza P., de Croon M.H.J.M., Van der Schaaf J., Schouten J.C. Liquid-liquid extraction systems of benzoic acid in water and heptane, methylbenzene or trichloroethylene as cosolvent. J. Chem. Eng. Data 2011, 56:3630-3636.
19. Shukla R.K., Kumar A., Shukla A., Srivastava K. Density, ultrasonic velocity, surface tension, excess volume and viscosity of quaternary fluid solutions. J. Mol. Liq. 2008, 140:117-122.
20. Shah R.K., London A.L. Laminar Flow Forced Convection in Ducts 1978, Academic Press, New York.