Comparing the effect of glucosamine and glucosamine with alendronate in symptomatic relieve of degenerative knee joint disease: A double-blind randomized clinical trial study

Jundishapur Journal of Natural Pharmaceutical Products

Volumn 7, Issue 3, 2012, Pages 87-92

  Arti, Hamid Reza ^a   Azemi, Mohammad Ebrahim ^a  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Alendronate; Clinical trial; Glucosamine; Osteoarthritis

Indexed keywords

ALENDRONIC ACID; GLUCOSAMINE;

ADULT; AGED; ANALGESIA; ARTICLE; BONE DENSITY; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; JOINT STIFFNESS; KNEE OSTEOARTHRITIS; KNEE PAIN; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

EID: 84866776323     PISSN: 17357780     EISSN: 22287876     Source Type: Journal    
DOI: 10.5812/jjnpp.3405     Document Type: Article

References (15)

1. Mankin HJ, Brandt KD. Biochemistry, metabolism and treatment of osteoarthritis. In: Moskowitz RW, editor. Osteoarthritis, diagnosis and management. 4 th ed. Philadelphia: W.B. Saunders; 2007. p. 109-19.
2. Haq SA, Davatchi F. Osteoarthritis of the knees in the COPCORD world. Int J Rheum Dis. 2011;14(2):122-9.
3. Houpt JB, McMillan R, Wein C, Paget-Dellio SD. Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee. J Rheumatol. 1999;26(11):2423-30.
4. Luke R, Bucci F. Nature and treatment optiom of osteoarthritis. ACA J Chirop. 2003;162:251-6.
5. McAlindon T, Formica M, LaValley M, Lehmer M, Kabbara K. Effectiveness of glucosamine for symptoms of knee osteoarthritis: results from an internet-based randomized double-blind controlled trial. Am J Med. 2004;117(9):643-9.
6. Cibere J, Kopec JA, Thorne A, Singer J, Canvin J, Robinson DB, et al. Randomized, double-blind, placebo-controlled glucosamine discontinuation trial in knee osteoarthritis. Arthritis Rheum. 2004;51(5):738-45.
7. Clegg DO, Reda DJ, Harris CL, Klein MA, O'Dell JR, Hooper MM, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med. 2006;354(8):795-808.
8. Qiu GX, Gao SN, Giacovelli G, Rovati L, Setnikar I. Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis. Arzneimittelforschung. 1998;48(5):469-74.
9. Carbone LD, Nevitt MC, Wildy K, Barrow KD, Harris F, Felson D, et al. The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis. Arthritis Rheum. 2004;50(11):3516-25.
10. Hayami T, Pickarski M, Wesolowski GA, McLane J, Bone A, Destefano J, et al. The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. Arthritis Rheum. 2004;50(4):1193-206.
11. Arti HR, Mehdinasab SA. The comparison effects of intra-articular injection of different opioids on postoperative pain relieve after arthroscopic anterior cruciate ligament reconstruction: A randomized clinical trial study. J Res Med Sci. 2011;16(9):1176-1182.
12. Heisel J, Forster KK. [Therapy of osteoarthritis crystalline glucosamine sulphate/a review of the clinical effcacy]. Arzneimittelforschung. 2007;57(4):203-17.
13. Chu SC, Yang SF, Lue KH, Hsieh YS, Lee CY, Chou MC, et al. Glucosamine sulfate suppresses the expressions of urokinase plasminogen activator and inhibitor and gelatinases during the early stage of osteoarthritis. Clin Chim Acta. 2006;372(1-2):167-72.
14. Distler J, Anguelouch A. Evidence-based practice: review of clinical evidence on the efficacy of glucosamine and chondroitin in the treatment of osteoarthritis. J Am Acad Nurse Pract. 2006;18(10):487-93.
15. Moroni A, Faldini C, Hoang-Kim A, Pegreffi F, Giannini S. Alendronate improves screw fixation in osteoporotic bone. J Bone Joint Surg Am. 2007;89(1):96-101.