Intrinsically superparamagnetic Fe-hydroxyapatite nanoparticles positively influence osteoblast-like cell behaviour

Journal of Nanobiotechnology

Volumn 10, Issue , 2012, Pages

  Panseri, Silvia ^a,b   Cunha, Carla ^a,b   D'Alessandro, Teresa ^b   Sandri, Monica ^b   Giavaresi, Gianluca ^a   Marcacci, Maurilio ^a   Hung, Clark T ^c   Tampieri, Anna ^b  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b INSTITUTE OF SCIENCE AND TECHNOLOGY FOR CERAMICS   (Italy)

^c Department of Earth and Environmental Sciences   (United States)

Author keywords

Hydroxyapatite; Nanoparticles; Orthopaedic applications; Static magnetic field; Superparamagnetism

Indexed keywords

BIOMEDICAL APPLICATIONS; BONE REMODELLING; BONE REPLACEMENT; BONE TISSUE ENGINEERING; BONE TISSUE REGENERATION; CLINICAL SETTINGS; CONTRAST AGENT; CRITICAL SIZE; DIAGNOSTIC IMAGING; FE-IONS; HUMAN OSTEOBLAST-LIKE CELLS; IN-VITRO; MAGNETIC DRUG DELIVERY; ORTHOPAEDIC APPLICATIONS; OSTEOBLAST-LIKE CELLS; STATIC MAGNETIC FIELDS; SUPERPARAMAGNETIC MATERIALS; SUPERPARAMAGNETIC NANOPARTICLES; SUPERPARAMAGNETICS; TISSUE ENGINEERING APPLICATIONS;

BIOCOMPATIBILITY; BONE; CELL PROLIFERATION; DRUG DELIVERY; HYDROXYAPATITE; IRON COMPOUNDS; MAGNETITE NANOPARTICLES; MEDICAL APPLICATIONS; NANOPARTICLES; SUPERPARAMAGNETISM; TISSUE; TISSUE ENGINEERING;

NANOMAGNETICS;

FERRIC ION; FERROUS ASCORBATE; FERROUS ION; HYDROXYAPATITE; NANOPARTICLE; SUPERPARAMAGNETIC IRON OXIDE;

ARTICLE; BIOCOMPATIBILITY; BONE LESION; BONE TISSUE; CELL CULTURE; CELL FUNCTION; CELL PROLIFERATION; CELL STRAIN; CELL STRUCTURE; CELL VIABILITY; DIAGNOSTIC IMAGING; DOPING; DRUG DELIVERY SYSTEM; EXPERIMENTAL RABBIT; HUMAN; HUMAN CELL; IN VIVO STUDY; MAGNETIC FIELD; OSTEOBLAST; TISSUE ENGINEERING;

ALKALINE PHOSPHATASE; ANIMALS; CELL PROLIFERATION; CELL SHAPE; DURAPATITE; FERRIC COMPOUNDS; FERROUS COMPOUNDS; HUMANS; MAGNETICS; NANOPARTICLES; OSTEOBLASTS; PILOT PROJECTS; RABBITS;

ORYCTOLAGUS CUNICULUS;

EID: 84866772738     PISSN: None     EISSN: 14773155     Source Type: Journal    
DOI: 10.1186/1477-3155-10-32     Document Type: Article

References (32)

1. Stevens MM. Biomaterials for bone tissue engineering. Materials Today 2008, 11:18-25.
2. Jones JR. New trends in bioactive scaffolds: The importance of nanostructure. J Eur Ceram Soc 2009, 29:1275-1281.
3. Petite H, Viateau V, Bensaid W, Meunier A, de Pollak C, Bourguignon M, Oudina K, Sedel L, Guillemin G. Tissue-engineered bone regeneration. Nat Biotechnol 2000, 18:959-963. 10.1038/79449, 10973216.
4. Tran N, Webster TJ. Nanotechnology for bone materials. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2009, 1:336-351. 10.1002/wnan.23, 20049801.
5. Dvir T, Timko BP, Kohane DS, Langer R. Nanotechnological strategies for engineering complex tissues. Nat Nanotechnol 2011, 6:13-22.
6. Zhang L, Webster TJ. Nanotechnology and nanomaterials: Promises for improved tissue regeneration. Nano Today 2009, 4:66-80.
7. Jain TK, Reddy MK, Morales MA, Leslie-Pelecky DL, Labhasetwar V. Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats. Mol Pharm 2008, 5:316-327. 10.1021/mp7001285, 18217714.
8. Prijic S, Scancar J, Romih R, Cemazar M, Bregar VB, Znidarsic A, Sersa G. Increased cellular uptake of biocompatible superparamagnetic iron oxide nanoparticles into malignant cells by an external magnetic field. J Membr Biol 2010, 236:167-179. 10.1007/s00232-010-9271-4, 2914263, 20602230.
9. Sun C, Du K, Fang C, Bhattarai N, Veiseh O, Kievit F, Stephen Z, Lee D, Ellenbogen RG, Ratner B, Zhang M. PEG-mediated synthesis of highly dispersive multifunctional superparamagnetic nanoparticles: their physicochemical properties and function in vivo. ACS nano 2010, 4:2402-2410. 10.1021/nn100190v, 2860962, 20232826.
10. Amirfazli A. Nanomedicine: magnetic nanoparticles hit the target. Nat Nanotechnol 2007, 2:467-468. 10.1038/nnano.2007.234, 18654342.
11. Glossop JR, Cartmell SH. Tensile strain and magnetic particle force application do not induce MAP3K8 and IL-1B differential gene expression in a similar manner to fluid shear stress in human mesenchymal stem cells. J Tissue Eng Regen Med 2010, 4:577-579. 10.1002/term.293, 20603871.
12. Gould P. Nanomagnetism Shows in Vivo Potential. Nano Today 2006, 1:34-39.
13. Arruebo M, Fernandez Pacheco R, Ibarra MR, Santamaria J. Magnetic Nanoparticles for Drug Delivery. Nano Today 2007, 2:22-32.
14. Kanczler JM, Sura HS, Magnay J, Green D, Oreffo RO, Dobson JP, El Haj AJ. Controlled differentiation of human bone marrow stromal cells using magnetic nanoparticle technology. Tissue Eng Part A 2010, 16:3241-3250. 10.1089/ten.tea.2009.0638, 20504072.
15. Buyukhatipoglu K, Chang R, Sun W, Clyne AM. Bioprinted nanoparticles for tissue engineering applications. Tissue Eng Part C Methods 2010, 16:631-642. 10.1089/ten.tec.2009.0280, 19769526.
16. Kim K, Fisher JP. Nanoparticle technology in bone tissue engineering. J Drug Target 2007, 15:241-252. 10.1080/10611860701289818, 17487693.
17. Abraham R, Walton J, Russell L, Wolman R, Wardley-Smith B, Green JR, Mitchell A, Reeve J. Dietary determinants of post-menopausal bone loss at the lumbar spine: a possible beneficial effect of iron. Osteoporos Int 2006, 17:1165-1173. 10.1007/s00198-005-0033-6, 16758136.
18. Harris MM, Houtkooper LB, Stanford VA, Parkhill C, Weber JL, Flint-Wagner H, Weiss L, Going SB, Lohman TG. Dietary iron is associated with bone mineral density in healthy postmenopausal women. J Nutr 2003, 133:3598-3602.
19. Le NT, Richardson DR. Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation. Blood 2004, 104:2967-2975. 10.1182/blood-2004-05-1866, 15251988.
20. Parelman M, Stoecker B, Baker A, Medeiros D. Iron restriction negatively affects bone in female rats and mineralization of hFOB osteoblast cells. Exp Biol Med (Maywood) 2006, 231:378-386.
21. Pareta RA, Taylor E, Webster TJ. Increased osteoblast density in the presence of novel calcium phosphate coated magnetic nanoparticles. Nanotechnology 2008, 19:265101. 10.1088/0957-4484/19/26/265101, 21828670.
22. Tampieri A, D'Alessandro T, Sandri M, Sprio S, Landi E, Bertinetti L, Panseri S, Pepponi G, Goettlicher J, Banobre-Lopez M, Rivas J. Intrinsic magnetism and hyperthermia in bioactive Fe-doped hydroxyapatite. Acta Biomater 2012, 8:843-851. 10.1016/j.actbio.2011.09.032, 22005331.
23. Yambe T, Inoue A, Sekine K, Shiraishi Y, Watanabe M, Yamaguchi T, Shibata M, Maruyama M, Konno S, Nitta S. Effect of the alternative magnetic stimulation on peripheral circulation for regenerative medicine. Biomed Pharmacother 2005, 59(Suppl 1):S174-S176.
24. Mayer-Wagner S, Passberger A, Sievers B, Aigner J, Summer B, Schiergens TS, Jansson V, Muller PE. Effects of low frequency electromagnetic fields on the chondrogenic differentiation of human mesenchymal stem cells. Bioelectromagnetics 2011, 32:283-290. 10.1002/bem.20633, 21452358.
25. Kasten A, Muller P, Bulnheim U, Groll J, Bruellhoff K, Beck U, Steinhoff G, Moller M, Rychly J. Mechanical integrin stress and magnetic forces induce biological responses in mesenchymal stem cells which depend on environmental factors. J Cell Biochem 2010, 111:1586-1597. 10.1002/jcb.22890, 21053275.
26. Jiang M, Terra J, Rossi AM, Morales MA, Saitovitch EMB, Ellis DE. Fe2+/Fe3+ substitution in hydroxyapatite: Theory and experiment. Phys Rev B 2002, 66:224107-224115.
27. Ramesh V, Ravichandran P, Copeland CL, Gopikrishnan R, Biradar S, Goornavar V, Ramesh GT, Hall JC. Magnetite induces oxidative stress and apoptosis in lung epithelial cells. Mol Cell Biochem 2012, 363:225-234. 10.1007/s11010-011-1174-x, 22147200.
28. Wu HC, Wang TW, Sun JS, Wang WH, Lin FH. A novel biomagnetic nanoparticle based on hydroxyapatite. Nanotechnology 2007, 18:1-9.
29. Wu Y, Jiang W, Wen X, He B, Zeng X, Wang G, Gu Z. A novel calcium phosphate ceramic-magnetic nanoparticle composite as a potential bone substitute. Biomed Mater 2010, 5:15001. 10.1088/1748-6041/5/1/015001, 20057017.
30. Miyakoshi J. Effects of static magnetic fields at the cellular level. Prog Biophys Mol Biol 2005, 87:213-223. 10.1016/j.pbiomolbio.2004.08.008, 15556660.
31. Kim YJ, Sah RL, Doong JY, Grodzinsky AJ. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem 1988, 174:168-176. 10.1016/0003-2697(88)90532-5, 2464289.
32. Teixeira CC, Hatori M, Leboy PS, Pacifici M, Shapiro IM. A rapid and ultrasensitive method for measurement of DNA, calcium and protein content, and alkaline phosphatase activity of chondrocyte cultures. Calcif Tissue Int 1995, 56:252-256. 10.1007/BF00298620, 7538446.