Effect of trigonelline and ethanol extract of Iraqi Fenugreek seeds on oxidative stress in alloxan diabetic rabbits

Journal of the Association of Arab Universities for Basic and Applied Sciences

Volumn 12, Issue 1, 2012, Pages 23-26

  Hamadi, Salim A ^a  

^a Petra University   (Jordan)

Author keywords

Antioxidant; Fenugreek seeds; Trigonelline

Indexed keywords

EID: 84866746804     PISSN: 18153852     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaubas.2012.02.003     Document Type: Article

References (22)

1. Adeeb, A.N., Hamadi, S.A., Al-Khateeb, E., 2002. Isolation of trigonelline from Iraqi fenugreek seeds and studying its effects on blood glucose & lipid profile in normal and alloxan-diabetic rabbits. A master thesis, College of Pharmacy/University of Baghdad.
2. Aisling M.A., Janet E.C., Gormley M.J., Ian S.Y. The effect of dietary treatment on lipid peroxidation and antioxidant status in newly diagnosed noninsulin dependent diabetes. Free Radical Biology and Medicine 1996, 21(5):719-726.
3. Ali L., Azad-Khan Hassan A.K. Characterization of the hypoglycemic effect of Trigonella-graceum seeds. Planta Medica 1995, 61(4):354-360.
4. Anuradha C., Ravikumar P. Anti-lipid activity of seeds of fenugreek (Trigonellina foenum-graecum). Medical Science Research 1998, 26:317-321.
5. Barham D., Trindoer P. An improved colour reagent from the determination of blood glucose by the oxidative system. Analyst 1972, 97:142-145.
6. Bordia A., Erma S.K., Srivastavam K.C. Effect of ginger and fenugreek on blood lipid, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 1997, 56:379-384.
7. Ghosal S., Srivastava R.S., Chatterjec D.C. Fenugreek a new steroidal sapnogenic-peptide ester of Trigonellina foenum-graecum. Phytochemistry 1974, 13:2247-2252.
8. Gilbert H.S., Stamp D.D., Roth E.F. A method to correct for errors caused by generation of interfering compounds during lipid peroxidation. Analytical Biochemistry 1984, 137:282-286.
9. Goldin D.V., Wohaib S.A., Garnett M.E. Antioxidant enzyme alteration in experimental and clinical diabetes. Molecular and Cellular Biochemistry 1988, 84:223-231.
10. Guerrero J.A., Navarro-Nunez L., Lozano M.L., Martinez C., Vicente V., Gibbins J.M., Rivera J. Flavonoids inhibit the platelets TxA2 signaling pathway & antagonize TxA2 receptors (TP) in platelets and smooth muscle cells. British Journal of Clinical Pharmacology 2007, 64(2):133-144.
11. Hettiarachchy N.S., Glenn K.C., Gnanasambandam R., Johnson M.G. Natural antioxidant from fenugreek. Journal of Food Science 1996, 61(3):516-519.
12. Kelly F.J. Use of antioxidants in the prevention and treatment of disease. Journal of International Federation of Clinical Chemistry 1998, 10(1):21-23.
13. Manson J.E., Gaziano J.M., Hennekens C.H. Antioxidants and cardiovascular disease: a review. Journal of American College of Nutrition 1993, 12(4):426-432.
14. Maxwell S.R. Prospects for the use of antioxidant therapies. Drugs 1995, 49(3):345-361.
15. Newall C.A., Anderson L.A., Phillipson J.D. Herbal medicine, A Guider for Health Care Professional 1996, The Pharmaceutical Press, London, pp. 117-118.
16. Rahimi R., Nikfar S.h., Larijani B., Adollahi M. A review on the role of antioxidant in the management of diabetes and its complications. Biomedicine & Pharmacotherapy 2005, 59(7):365-373.
17. Shah N., Bodhankar S.L., Badole S.l., Kamble H.V., Mohan V. Effect of trigonelline: an active compound from Trigonelline Foenumgraecumlinn in alloxan. Journal of Cell and Tissue Research 2006, 6(1):585-590.
18. Stocks S., Dormandy T.C. The auto oxidation of human red cell lipid induced by hydrogen peroxide. British Journal of Hematology 1971, 20:95-111.
19. Syeda Birjees Bukhari, Muhammad qba Banger., Shahabuddin Memon Antioxidative activity of extract from Fenugreek seeds (Trigonella Foenum-graecum). Pakistan Journal of Analytical and Environmental Chemistry 2008, 9(2).
20. Toppo F.A., Akhand R., Pathak A.K. Pharmacological actions and potential uses of Trigonella Foenum-Graecum: a review articl. Asian Journal of Pharmaceutical and Clinical Research 2009, 2(4):29-38.
21. Velikii N.N., Obrosova I.G., Efimoy A.S. Nicotinamide coenzyme in the regulation of cellular metabolism in various types of diabetes. Vopr Med Khim 1992, 38(4):45-52.
22. Young I.S., Woodside J.V. Antioxidants in health and disease. Journal of Clinical Pathology 2001, 54:176-186.