-
1
-
-
33750576990
-
The role of serendipity in drug discovery
-
T.A. Ban The role of serendipity in drug discovery Dialogues Clin. Neurosci. 8 2006 335 344 (Pubitemid 44682750)
-
(2006)
Dialogues in Clinical Neuroscience
, vol.8
, Issue.3
, pp. 335-344
-
-
Ban, T.A.1
-
2
-
-
0011496063
-
Étude expérimentale du syndrome d'irritation et application clinique à la maladie post-traumatique
-
(in French)
-
H. Laborit Étude expérimentale du syndrome d'irritation et application clinique à la maladie post-traumatique Thérapie 4 1949 126 139 (in French)
-
(1949)
Thérapie
, vol.4
, pp. 126-139
-
-
Laborit, H.1
-
3
-
-
33750587274
-
Un nouveau stabilisateur végétative (le 4560 RP)
-
H. Laborit Un nouveau stabilisateur végétative (le 4560 RP) Presse Méd. 60 1952 37 348
-
(1952)
Presse Méd.
, vol.60
, pp. 37-348
-
-
Laborit, H.1
-
4
-
-
0016592484
-
Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons
-
P. Seeman, and T. Lee Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons Science 188 1975 1217 1219
-
(1975)
Science
, vol.188
, pp. 1217-1219
-
-
Seeman, P.1
Lee, T.2
-
5
-
-
58049157203
-
Second-generation versus first-generation antipsychotic drugs for schizophrenia: A meta-analysis
-
S. Leucht Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis Lancet 373 2009 31 41
-
(2009)
Lancet
, vol.373
, pp. 31-41
-
-
Leucht, S.1
-
6
-
-
66949133915
-
Cognitive effects of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: A randomized, open-label clinical trial (EUFEST)
-
M. Davidson Cognitive effects of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: a randomized, open-label clinical trial (EUFEST) Am. J. Psychiatry 166 2009 675 682
-
(2009)
Am. J. Psychiatry
, vol.166
, pp. 675-682
-
-
Davidson, M.1
-
7
-
-
0023812652
-
Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
-
J. Kane Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine Arch. Gen. Psychiatry 45 1988 789 796
-
(1988)
Arch. Gen. Psychiatry
, vol.45
, pp. 789-796
-
-
Kane, J.1
-
8
-
-
0035660215
-
2 receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient
-
DOI 10.1016/S0006-3223(01)01251-3, PII S0006322301012513
-
2 receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient Biol. Psychiatry 50 2001 873 883 (Pubitemid 34020700)
-
(2001)
Biological Psychiatry
, vol.50
, Issue.11
, pp. 873-883
-
-
Kapur, S.1
Remington, G.2
-
9
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
-
DOI 10.1038/nm1632, PII NM1632
-
S.T. Patil Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial Nat. Med. 13 2007 1102 1107 (Pubitemid 47517511)
-
(2007)
Nature Medicine
, vol.13
, Issue.9
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
Lowe, S.L.4
Jackson, K.A.5
Andreev, B.V.6
Avedisova, A.S.7
Bardenstein, L.M.8
Gurovich, I.Y.9
Morozova, M.A.10
Mosolov, S.N.11
Neznanov, N.G.12
Reznik, A.M.13
Smulevich, A.B.14
Tochilov, V.A.15
Johnson, B.G.16
Monn, J.A.17
Schoepp, D.D.18
-
10
-
-
64249168387
-
Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia
-
J.W. Young Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia Pharmacol. Ther. 122 2009 150 202
-
(2009)
Pharmacol. Ther.
, vol.122
, pp. 150-202
-
-
Young, J.W.1
-
11
-
-
84855927044
-
Targeting glutamate synapses in schizophrenia
-
J.R. Field Targeting glutamate synapses in schizophrenia Trends Mol. Med. 17 2011 689 698
-
(2011)
Trends Mol. Med.
, vol.17
, pp. 689-698
-
-
Field, J.R.1
-
12
-
-
80053231891
-
Translational neuroscience of schizophrenia: Seeking a meeting of minds between mouse and man
-
M.J. Kas Translational neuroscience of schizophrenia: seeking a meeting of minds between mouse and man Sci. Transl. Med. 3 2011 102mr3
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Kas, M.J.1
-
14
-
-
77954513019
-
Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia
-
M.J. Owen Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia Arch. Gen. Psychiatry 67 2010 667 673
-
(2010)
Arch. Gen. Psychiatry
, vol.67
, pp. 667-673
-
-
Owen, M.J.1
-
15
-
-
75749135692
-
Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: A 30-year study
-
A. Reichenberg Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: a 30-year study Am. J. Psychiatry 167 2010 160 169
-
(2010)
Am. J. Psychiatry
, vol.167
, pp. 160-169
-
-
Reichenberg, A.1
-
17
-
-
0027965383
-
Childhood antecedents of schizophrenia and affective illness: Social adjustment at ages 7 and 11
-
D.J. Done Childhood antecedents of schizophrenia and affective illness: a social adjustment at ages 7 and 11 Br. Med. J. 309 1994 699 703 (Pubitemid 24285221)
-
(1994)
British Medical Journal
, vol.309
, Issue.6956
, pp. 699-703
-
-
Done, D.J.1
Crow, T.J.2
Johnstone, E.C.3
Sacker, A.4
-
18
-
-
12344327212
-
Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
-
DOI 10.1038/sj.mp.4001558
-
P.J. Harrison, and D.R. Weinberger Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence Mol. Psychiatry 10 2005 40 68 (Pubitemid 40139588)
-
(2005)
Molecular Psychiatry
, vol.10
, Issue.1
, pp. 40-68
-
-
Harrison, P.J.1
Weinberger, D.R.2
-
19
-
-
40049102475
-
What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia
-
DOI 10.1093/schbul/sbm168
-
H.E. Hulshoff Pol, and R.S. Kahn What happens after the first episode? A review of progressive brain changes in chronically ill patients with schizophrenia Schizophr. Bull. 34 2008 354 366 (Pubitemid 351323347)
-
(2008)
Schizophrenia Bulletin
, vol.34
, Issue.2
, pp. 354-366
-
-
Hulshoff Pol, H.E.1
Kahn, R.S.2
-
20
-
-
80052528577
-
Changes in cortical thickness during the course of illness in schizophrenia
-
N.E. van Haren Changes in cortical thickness during the course of illness in schizophrenia Arch. Gen. Psychiatry 68 2011 871 880
-
(2011)
Arch. Gen. Psychiatry
, vol.68
, pp. 871-880
-
-
Van Haren, N.E.1
-
21
-
-
57649140590
-
Removing obstacles in neuroscience drug discovery: The future path for animal models
-
A. Markou Removing obstacles in neuroscience drug discovery: the future path for animal models Neuropsychopharmacol. Rev. 34 2009 74 89
-
(2009)
Neuropsychopharmacol. Rev.
, vol.34
, pp. 74-89
-
-
Markou, A.1
-
22
-
-
0034917841
-
Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: A decade in review
-
DOI 10.1007/s002130100811
-
M.A. Geyer Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review Psychopharmacology 156 2001 117 154 (Pubitemid 32702206)
-
(2001)
Psychopharmacology
, vol.156
, Issue.2-3
, pp. 117-154
-
-
Geyer, M.A.1
Krebs-Thomson, K.2
Braff, D.L.3
Swerdlow, N.R.4
-
23
-
-
0021076496
-
Control of behavior by intravenous nicotine injections in human subjects
-
J.E. Henningfield, and S.R. Goldberg Control of behavior by intravenous nicotine injections in human subjects Pharmacol. Biochem. Behav. 19 1983 1021 1026 (Pubitemid 14209528)
-
(1983)
Pharmacology Biochemistry and Behavior
, vol.19
, Issue.6
, pp. 1021-1026
-
-
Henningfield, J.E.1
Goldberg, S.R.2
-
24
-
-
33846858426
-
2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid
-
DOI 10.1016/j.neuropharm.2006.10.016, PII S0028390806003789
-
2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid Neuropharmacology 52 2007 985 994 (Pubitemid 46227486)
-
(2007)
Neuropharmacology
, vol.52
, Issue.3
, pp. 985-994
-
-
Rollema, H.1
Chambers, L.K.2
Coe, J.W.3
Glowa, J.4
Hurst, R.S.5
Lebel, L.A.6
Lu, Y.7
Mansbach, R.S.8
Mather, R.J.9
Rovetti, C.C.10
Sands, S.B.11
Schaeffer, E.12
Schulz, D.W.13
Tingley III, F.D.14
Williams, K.E.15
-
25
-
-
0032495515
-
Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine
-
DOI 10.1038/34413
-
M.R. Picciotto Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine Nature 391 1998 173 177 (Pubitemid 28092475)
-
(1998)
Nature
, vol.391
, Issue.6663
, pp. 173-177
-
-
Picciotto, M.R.1
Zoli, M.2
Rimondini, R.3
Lena, C.4
Marubio, L.M.5
Pich, E.M.6
Fuxe, K.7
Changeux, J.-P.8
-
26
-
-
21844438972
-
Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors
-
DOI 10.1038/nature03694
-
U. Maskos Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors Nature 436 2005 103 107 (Pubitemid 40966193)
-
(2005)
Nature
, vol.436
, Issue.7047
, pp. 103-107
-
-
Maskos, U.1
Molles, B.E.2
Pons, S.3
Besson, M.4
Guiard, B.P.5
Guilloux, J.-P.6
Evrard, A.7
Cazala, P.8
Cormier, A.9
Mameli-Engvall, M.10
Dufour, N.11
Cloez-Tayarani, I.12
Bemelmans, A.-P.13
Mallet, J.14
Gardier, A.M.15
David, V.16
Faure, P.17
Granon, S.18
Changeux, J.-P.19
-
27
-
-
77649238532
-
2 nicotinic acetylcholine- receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in rats
-
2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in rats Psychopharmacology 208 2010 365 376
-
(2010)
Psychopharmacology
, vol.208
, pp. 365-376
-
-
O'Connor, E.C.1
-
28
-
-
34347344890
-
2 nACh receptors for smoking cessation
-
DOI 10.1016/j.tips.2007.05.003, PII S0165614707001277
-
2 nACh receptors for smoking cessation Trends Pharmacol. Sci. 28 2007 316 325 (Pubitemid 47016686)
-
(2007)
Trends in Pharmacological Sciences
, vol.28
, Issue.7
, pp. 316-325
-
-
Rollema, H.1
Coe, J.W.2
Chambers, L.K.3
Hurst, R.S.4
Stahl, S.M.5
Williams, K.E.6
-
29
-
-
78649650201
-
Glutamate receptors in extinction and extinction-based therapies for psychiatric illness
-
K.M. Myers Glutamate receptors in extinction and extinction-based therapies for psychiatric illness Neuropsychopharmacology 36 2011 274 293
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 274-293
-
-
Myers, K.M.1
-
30
-
-
0037088911
-
Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats
-
D.L. Walker Facilitation of conditioned fear extinction by systemic administration of D-cycloserine as assessed with fear-potentiated startle in rats J. Neurosci. 22 2002 2343 2351 (Pubitemid 35386533)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.6
, pp. 2343-2351
-
-
Walker, D.L.1
Ressler, K.J.2
Lu, K.-T.3
Davis, M.4
-
31
-
-
33747083749
-
Effects of D-cycloserine on extinction: Translation from preclinical to clinical work
-
DOI 10.1016/j.biopsych.2006.03.084, PII S0006322306007311
-
M. Davis Effects of D-cycloserine on extinction: translation from preclinical to clinical work Biol. Psychiatry 60 2006 369 375 (Pubitemid 44215855)
-
(2006)
Biological Psychiatry
, vol.60
, Issue.4
, pp. 369-375
-
-
Davis, M.1
Ressler, K.2
Rothbaum, B.O.3
Richardson, R.4
-
32
-
-
79952258566
-
Pharmacological enhancement of behavioral therapy: Focus on posttraumatic stress disorder
-
D.C. Choi Pharmacological enhancement of behavioral therapy: focus on posttraumatic stress disorder Curr. Top. Behav. Neurosci. 2 2009 279 299
-
(2009)
Curr. Top. Behav. Neurosci.
, vol.2
, pp. 279-299
-
-
Choi, D.C.1
-
33
-
-
4644355629
-
Cognitive enhancers as adjuncts to psychotherapy: Use of D-cycloserine in phobic individuals to facilitate extinction of fear
-
DOI 10.1001/archpsyc.61.11.1136
-
K.J. Ressler Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear Arch. Gen. Psychiatry 61 2004 1136 1144 (Pubitemid 39463415)
-
(2004)
Archives of General Psychiatry
, vol.61
, Issue.11
, pp. 1136-1144
-
-
Ressler, K.J.1
Rothbaum, B.O.2
Tannenbaum, L.3
Anderson, P.4
Graap, K.5
Zimand, E.6
Hodges, L.7
Davis, M.8
-
34
-
-
44349151445
-
A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy
-
M.M. Norberg A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy Biol. Psychiatry 63 2008 1118 1126
-
(2008)
Biol. Psychiatry
, vol.63
, pp. 1118-1126
-
-
Norberg, M.M.1
-
36
-
-
79952259518
-
Models of neurodevelopmental abnormalities in schizophrenia
-
S.B. Powell Models of neurodevelopmental abnormalities in schizophrenia Curr. Top. Behav. Neurosci. 4 2010 435 483
-
(2010)
Curr. Top. Behav. Neurosci.
, vol.4
, pp. 435-483
-
-
Powell, S.B.1
-
37
-
-
84857053370
-
The role of the α7 nicotinic receptor in cognitive processing of persons with schizophrenia
-
C.G. AhnAllen The role of the α7 nicotinic receptor in cognitive processing of persons with schizophrenia Curr. Opin. Psychiatry 25 2012 103 108
-
(2012)
Curr. Opin. Psychiatry
, vol.25
, pp. 103-108
-
-
Ahnallen, C.G.1
-
38
-
-
84855979108
-
Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia
-
D. Alberati Glycine reuptake inhibitor RG1678: a pharmacologic characterization of an investigational agent for the treatment of schizophrenia Neuropharmacology 62 2012 1152 1161
-
(2012)
Neuropharmacology
, vol.62
, pp. 1152-1161
-
-
Alberati, D.1
-
39
-
-
77957885222
-
New opportunities in the treatment of cognitive impairments associated with schizophrenia
-
M.A. Geyer New opportunities in the treatment of cognitive impairments associated with schizophrenia Curr. Dir. Psychol. Sci. 19 2010 264 269
-
(2010)
Curr. Dir. Psychol. Sci.
, vol.19
, pp. 264-269
-
-
Geyer, M.A.1
-
40
-
-
26444539074
-
Developing predictive animal models and establishing a preclinical trials network for assessing treatment effects on cognition in schizophrenia
-
DOI 10.1093/schbul/sbi041
-
S. Floresco Developing predictive animal models and establishing a preclinical trials network for assessing treatment effects on cognition in schizophrenia Schizophr. Bull. 31 2005 888 894 (Pubitemid 41437783)
-
(2005)
Schizophrenia Bulletin
, vol.31
, Issue.4
, pp. 888-894
-
-
Floresco, S.B.1
Geyer, M.A.2
Gold, L.H.3
Grace, A.A.4
-
43
-
-
33747066395
-
Contextual and temporal modulation of extinction: Behavioral and biological mechanisms
-
DOI 10.1016/j.biopsych.2005.12.015, PII S0006322306000990
-
M.E. Bouton Contextual and temporal modulation of extinction: behavioral and biological mechanisms Biol. Psychiatry 60 2006 352 360 (Pubitemid 44215847)
-
(2006)
Biological Psychiatry
, vol.60
, Issue.4
, pp. 352-360
-
-
Bouton, M.E.1
Westbrook, R.F.2
Corcoran, K.A.3
Maren, S.4
-
44
-
-
33846478897
-
Mechanisms of fear extinction
-
DOI 10.1038/sj.mp.4001939, PII 4001939
-
K.M. Myers, and M. Davis Mechanisms of fear extinction Mol. Psychiatry 12 2007 120 150 (Pubitemid 46160979)
-
(2007)
Molecular Psychiatry
, vol.12
, Issue.2
, pp. 120-150
-
-
Myers, K.M.1
Davis, M.2
-
45
-
-
80155157843
-
Molecular mechanisms of fear learning and memory
-
J.P. Johansen Molecular mechanisms of fear learning and memory Cell 147 2011 509 524
-
(2011)
Cell
, vol.147
, pp. 509-524
-
-
Johansen, J.P.1
-
46
-
-
82955229598
-
Fear extinction as a model for translational neuroscience: Ten years of progress
-
M.R. Milad, and G.J. Quirk Fear extinction as a model for translational neuroscience: ten years of progress Annu. Rev. Psychol. 63 2012 129 151
-
(2012)
Annu. Rev. Psychol.
, vol.63
, pp. 129-151
-
-
Milad, M.R.1
Quirk, G.J.2
-
47
-
-
26944446159
-
Contributions of the amygdala to emotion processing: From animal models to human behavior
-
DOI 10.1016/j.neuron.2005.09.025, PII S0896627305008238
-
E.A. Phelps, and J.E. LeDoux Contributions of the amygdala to emotion processing: from animal models to human behavior Neuron 48 2005 175 187 (Pubitemid 41476352)
-
(2005)
Neuron
, vol.48
, Issue.2
, pp. 175-187
-
-
Phelps, E.A.1
LeDoux, J.E.2
|